| Year |
Title |
Altmetric |
| 2020
|
Nuclear receptor binding factor 2 (NRBF2) is required for learning and memory.
Laboratory Investigation.
100:1238-1251.
2020
|
|
| 2020
|
Role of O-Linked N-acetylglucosamine (O-GlcNAc) Protein Modification in Cellular (Patho)Physiology..
Physiological Reviews.
2020
|
|
| 2020
|
Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia
2020
|
|
| 2020
|
Differential effects of REV-ERB/ agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption
2020
|
|
| 2020
|
Role and Mechanisms of Mitophagy in Liver Diseases..
Cells.
9.
2020
|
|
| 2020
|
MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure
2020
|
|
| 2020
|
Autophagy-related protein PIK3C3/VPS34 controls T cell metabolism and function: PIK3C3/VPS34 in T cell metabolism and function.
Autophagy.
2020
|
|
| 2020
|
Circadian Regulation of Cardiac Physiology: Rhythms That Keep the Heart Beating.
Annual Review of Physiology.
82:79-101.
2020
|
|
| 2020
|
Pik3c3 deficiency in myeloid cells imparts partial resistance to experimental autoimmune encephalomyelitis associated with reduced IL-1β production.
Cellular and Molecular Immunology.
2020
|
|
| 2020
|
Restoration of CTSD (cathepsin D) and lysosomal function in stroke is neuroprotective.
Autophagy.
2020
|
|
| 2019
|
Acute increases in O-glcNAc indirectly impair mitochondrial bioenergetics through dysregulation of lonp1-mediated mitochondrial protein complex turnover
2019
|
|
| 2019
|
Bioenergetics and translational metabolism: Implications for genetics, physiology and precision medicine
2019
|
|
| 2018
|
Exosomal transfer of mitochondria from airway myeloid-derived regulatory cells to T cells.
Redox Biology.
18:54-64.
2018
|
|
| 2018
|
Identification of Compounds That Decrease Glioblastoma Growth and Glucose Uptake in Vitro.
ACS Chemical Biology.
13:2048-2057.
2018
|
|
| 2018
|
Methods for assessing mitochondrial quality control mechanisms and cellular consequences in cell culture.
Redox Biology.
17:59-69.
2018
|
|
| 2018
|
Temporal partitioning of adaptive responses of the murine heart to fasting.
Life Sciences.
197:30-39.
2018
|
|
| 2018
|
Mitochondrial function and autophagy: integrating proteotoxic, redox, and metabolic stress in Parkinson's disease.
Journal of Neurochemistry.
144:691-709.
2018
|
|
| 2018
|
The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson's disease brain in association with the pathologic accumulation of alpha-synuclein.
Neurobiology of Disease.
110:68-81.
2018
|
|
| 2018
|
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation.
Journal of Biological Chemistry.
293:1218-1228.
2018
|
|
| 2018
|
Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activation..
Journal of Biological Chemistry.
293:1218-1228.
2018
|
|
| 2017
|
Regulation of autophagy, mitochondrial dynamics, and cellular bioenergetics by 4-hydroxynonenal in primary neurons.
Autophagy.
13:1828-1840.
2017
|
|
| 2017
|
Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.
Journal of Molecular and Cellular Cardiology.
110:80-95.
2017
|
|
| 2017
|
Autophagy-related protein Vps34 controls the homeostasis and function of antigen cross-presenting CD8α+ dendritic cells
2017
|
|
| 2017
|
O-GlcNAc regulation of autophagy and α-synuclein homeostasis; Implications for Parkinson's disease.
Molecular Brain.
10.
2017
|
|
| 2017
|
Haplodeficiency of Cathepsin D does not affect cerebral amyloidosis and autophagy in APP/PS1 transgenic mice.
Journal of Neurochemistry.
142:297-304.
2017
|
|
| 2017
|
Myocardial Upregulation of Cathepsin D by Ischemic Heart Disease Promotes Autophagic Flux and Protects Against Cardiac Remodeling and Heart Failure.
Circulation: Heart Failure.
10.
2017
|
|
| 2017
|
O-GlcNAcylation and neurodegeneration.
Brain Research Bulletin.
133:80-87.
2017
|
|
| 2017
|
Oxidative stress and neurodegeneration.
Brain Research Bulletin.
133:1-3.
2017
|
|
| 2017
|
Autophagy and the redox connection: Virtual collection Vol 2.
Redox Biology.
11:620-621.
2017
|
|
| 2017
|
Inhibition of autophagy with bafilomycin and chloroquine decreases mitochondrial quality and bioenergetic function in primary neurons.
Redox Biology.
11:73-81.
2017
|
|
| 2017
|
Trehalose does not improve neuronal survival on exposure to alpha-synuclein pre-formed fibrils.
Redox Biology.
11:429-437.
2017
|
|
| 2017
|
NADPH Oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway.
Journal of Biological Chemistry.
292:3029-3038.
2017
|
|
| 2016
|
Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism.
Free Radical Biology and Medicine.
100:94-107.
2016
|
|
| 2016
|
Differential regulation of autophagy and mitophagy in pulmonary diseases
2016
|
|
| 2016
|
Abrogation of Nrf2 impairs antioxidant signaling and promotes atrial hypertrophy in response to high-intensity exercise stress.
Journal of Translational Medicine.
14.
2016
|
|
| 2016
|
Metabolic, autophagic, and mitophagic activities in cancer initiation and progression.
Biomedical Journal.
39:98-106.
2016
|
|
| 2016
|
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy.
12:1-222.
2016
|
|
| 2016
|
Linking genomic reorganization to tumor initiation via the giant cell cycle.
Oncogenesis.
5.
2016
|
|
| 2016
|
Novel mechanisms for the antifibrotic action of nintedanib.
American Journal of Respiratory Cell and Molecular Biology.
54:51-59.
2016
|
|
| 2016
|
The role of autophagy, mitophagy and lysosomal functions in modulating bioenergetics and survival in the context of redox and proteotoxic damage: Implications for neurodegenerative diseases.
Aging and Disease.
7:150-162.
2016
|
|
| 2015
|
Erratum: KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity (Biochemical Journal (2015) 469 (347-355)).
Biochemical Journal.
471:431.
2015
|
|
| 2015
|
KEAP1-NRF2 signalling and autophagy in protection against oxidative and reductive proteotoxicity.
Biochemical Journal.
469:347-355.
2015
|
|
| 2015
|
Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation.
Free Radical Biology and Medicine.
85:83-94.
2015
|
|
| 2015
|
Teaching the basics of autophagy and mitophagy to redox biologists-Mechanisms and experimental approaches.
Redox Biology.
4:242-259.
2015
|
|
| 2015
|
Regulation of autophagy by protein post-translational modification.
Laboratory Investigation.
95:14-25.
2015
|
|
| 2014
|
SCCA1/SERPINB3 promotes oncogenesis and epithelial-mesenchymal transition via the unfolded protein response and IL6 signaling.
Cancer Research.
74:6318-6329.
2014
|
|
| 2014
|
Aging and energetics' 'Top 40' future research opportunities 2010-2013.
F1000Research.
3.
2014
|
|
| 2014
|
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease.
Redox Biology.
2:82-90.
2014
|
|
| 2014
|
Bioenergetic adaptation in response to autophagy regulators during rotenone exposure.
Journal of Neurochemistry.
131:625-633.
2014
|
|
| 2014
|
Mitophagy mechanisms and role in human diseases
2014
|
|
| 2014
|
Over-expression of an inactive mutant cathepsin D increases endogenous alpha-synuclein and cathepsin B activity in SH-SY5Y cells.
Journal of Neurochemistry.
128:950-961.
2014
|
|
| 2014
|
Redox regulation of antioxidants, autophagy, and the response to stress: Implications for electrophile therapeutics.
Free Radical Biology and Medicine.
71:196-207.
2014
|
|
| 2014
|
The Bioenergetic Health Index: a new concept in mitochondrial translational research..
Clinical Science.
127:367-373.
2014
|
|
| 2014
|
The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.
Autophagy.
10:986-1003.
2014
|
|
| 2013
|
Inhibition of glycolysis attenuates 4-hydroxynonenal-dependent autophagy and exacerbates apoptosis in differentiated SH-SY5Y neuroblastoma cells.
Autophagy.
9:1996-2008.
2013
|
|
| 2013
|
Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived β-cells
2013
|
|
| 2013
|
Bioenergetic and autophagic control by Sirt3 in response to nutrient deprivation in mouse embryonic fibroblasts.
Biochemical Journal.
454:249-257.
2013
|
|
| 2013
|
Impaired autophagy, defective t cell homeostasis, and a wasting syndrome in mice with a t cell-specific deletion of Vps34.
Journal of Immunology.
190:5086-5101.
2013
|
|
| 2013
|
Specific Distribution of the Autophagic Protein GABARAPL1/GEC1 in the Developing and Adult Mouse Brain and Identification of Neuronal Populations Expressing GABARAPL1/GEC1.
PLoS ONE.
8.
2013
|
|
| 2013
|
Dopamine and its metabolites in cathepsin D heterozygous mice before and after MPTP administration.
Neuroscience Letters.
538:3-8.
2013
|
|
| 2013
|
ICAD Deficiency in Human Colon Cancer and Predisposition to Colon Tumorigenesis: Linkage to Apoptosis Resistance and Genomic Instability.
PLoS ONE.
8.
2013
|
|
| 2013
|
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly(ADP-ribose) polymerase-regulated DNAS1L3, an endoplasmic reticulum-localized endonucleasethat translocates to the nucleus during apoptosis.
Journal of Biological Chemistry.
288:3460-3468.
2013
|
|
| 2013
|
Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: Implications for mitochondrial therapeutics.
Biochemical Society Transactions.
41:127-133.
2013
|
|
| 2013
|
Apoptotic DNA fragmentation may be a cooperative activity between caspase-activated deoxyribonuclease and the poly (ADP-ribose) polymerase-regulated DNAS1....
Journal of Biological Chemistry.
288:3460-3468.
2013
|
|
| 2013
|
Autophagy and mitophagy in cellular damage control.
Redox Biology.
1:19-23.
2013
|
|
| 2013
|
Autophagy and mitophagy in cellular damage control.
Redox Biology.
1:19-23.
2013
|
|
| 2013
|
Autophagy as an essential cellular antioxidant pathway in neurodegenerative disease, Redox Biology 2 (2014) 82–90
2013
|
|
| 2013
|
Cellular metabolic and autophagic pathways: Traffic control by redox signaling.
Free Radical Biology and Medicine.
63:207-221.
2013
|
|
| 2013
|
Dysfunctional mitochondrial bioenergetics and oxidative stress in Akita+/Ins2-derived β-cells.
American Journal of Physiology-Endocrinology and Metabolism 305 (5), E585-.
599.
2013
|
|
| 2013
|
Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons.
Free Radical Biology and Medicine.
65:1215-1228.
2013
|
|
| 2013
|
Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.
Free Radical Biology and Medicine.
59:56-68.
2013
|
|
| 2012
|
Integration of cellular bioenergetics with mitochondrial quality control and autophagy
2012
|
|
| 2012
|
Distinct Effects of Rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on Cellular Bioenergetics and Cell Death.
PLoS ONE.
7.
2012
|
|
| 2012
|
Genetically engineered mouse models of Parkinson's disease.
Brain Research Bulletin.
88:13-32.
2012
|
|
| 2012
|
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy.
8:445-544.
2012
|
|
| 2012
|
Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: The protective role of autophagy
2012
|
|
| 2012
|
Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function
2012
|
|
| 2012
|
Autophagy, mitochondria and oxidative stress: Cross-talk and redox signalling.
Biochemical Journal.
441:523-540.
2012
|
|
| 2012
|
Mammalian PIK3C3/VPS34: The key to autophagic processing in liver and heart.
Autophagy.
8:707-708.
2012
|
|
| 2011
|
Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress.
Free Radical Biology and Medicine.
51:2007-2017.
2011
|
|
| 2011
|
Assessing bioenergetic function in response to oxidative stress by metabolic profiling.
Free Radical Biology and Medicine.
51:1621-1635.
2011
|
|
| 2011
|
Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons.
Molecular Neurodegeneration.
6.
2011
|
|
| 2011
|
Systems biology of the autophagy-lysosomal pathway.
Autophagy.
7:477-489.
2011
|
|
| 2010
|
Lysosomal function in macromolecular homeostasis and bioenergetics in Parkinson's disease.
Molecular Neurodegeneration.
5.
2010
|
|
| 2010
|
Lysosome dysfunction triggers Atg7-dependent neural apoptosis.
Journal of Biological Chemistry.
285:10497-10507.
2010
|
|
| 2009
|
Inhibition of lysosomal functions reduces proteasomal activity.
Neuroscience Letters.
456:15-19.
2009
|
|
| 2008
|
Fos regulates neuronal activity in the nucleus accumbens.
Neuroscience Letters.
448:157-160.
2008
|
|
| 2008
|
The autophagy-lysosomal degradation pathway: Role in neurodegenerative disease and therapy.
Frontiers in Bioscience.
13:718-736.
2008
|
|
| 2008
|
Differential activation of c-Fos and caspase-3 in hippocampal neuron subpopulations following neonatal hypoxia-ischemia.
Journal of Neuroscience Research.
86:1115-1124.
2008
|
|
| 2008
|
A neuroprotective role of lysosomal enzyme cathepsin D against a-synuclein pathogenesis.
Movement Disorders 23 (1), S8-S.
8.
2008
|
|
| 2008
|
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity..
Molecular Brain.
1:17.
2008
|
|
| 2007
|
Lack of self-administration of cocaine in dopamine D1 receptor knock-out mice
2007
|
|
| 2007
|
Dopamine D1 and D3 receptors oppositely regulate NMDA- and cocaine-induced MAPK signaling via NMDA receptor phosphorylation.
Journal of Neurochemistry.
103:840-848.
2007
|
|
| 2007
|
Deficiency of DNA fragmentation factor 45 results in reduced oocyte apoptosis in response to doxorubicin.
Cell Research.
17:735-736.
2007
|
|
| 2007
|
The dopamine D3 receptor antagonist NGB 2904 increases spontaneous and amphetamine-stimulated locomotion
2007
|
|
| 2007
|
Kainic acid induces early and transient autophagic stress in mouse hippocampus.
Neuroscience Letters.
414:57-60.
2007
|
|
| 2007
|
The Aedes albopictus inhibitor of apoptosis 1 gene protects vertebrate cells from bluetongue virus-induced apoptosis.
Insect Molecular Biology.
16:93-105.
2007
|
|
| 2007
|
Effects of acute "binge" cocaine on mRNA levels of μ opioid receptor and neuropeptides in dopamine D1 or D3 receptor knockout mice
2007
|
|
| 2006
|
c-Fos facilitates the acquisition and extinction of cocaine-induced persistent changes
2006
|
|
| 2006
|
Dose-response analysis of locomotor activity and stereotypy in dopamine D3 receptor mutant mice following acute amphetamine
2006
|
|
| 2006
|
Deficient hippocampal c-fos expression results in reduced anxiety and altered response to chronic stress in female mice.
Neuroscience Letters.
403:125-130.
2006
|
|
| 2006
|
c-fos modulates brain-derived neurotrophic factor mRNA expression in mouse hippocampal CA3 and dentate gyrus neurons.
Neuroscience Letters.
400:177-180.
2006
|
|
| 2006
|
Deficient hippocampal c-fos expression results in reduced anxiety and altered response to chronic stress in female mice.
Neuroscience Letters.
403:125-130.
2006
|
|
| 2006
|
Opposite regulation of cocaine-induced intracellular signaling and gene expression by dopamine D1 and D3 receptors.
Annals of the New York Academy of Sciences.
1074:1-12.
2006
|
|
| 2006
|
c-fos modulates brain-derived neurotrophic factor mRNA expression in mouse hippocampal CA3 and dentate gyrus neurons.
Neuroscience Letters.
400:177-180.
2006
|
|
| 2005
|
Repeated cocaine administration induces gene expression changes through the dopamine D1 receptors.
Neuropsychopharmacology.
30:1443-1454.
2005
|
|
| 2005
|
Erythropoietin prevents the acute myocardial inflammatory response induced by ischemia/reperfusion via induction of AP-1.
Cardiovascular Research.
65:719-727.
2005
|
|
| 2005
|
Gene expression changes induced by repeated cocaine administration through the dopamine D1 receptors.
Neuropsychopharmacology.
30:1443-1454.
2005
|
|
| 2004
|
Neural system-enriched gene expression: Relationship to biological pathways and neurological diseases.
Physiological Genomics.
18:167-183.
2004
|
|
| 2004
|
Molecular genetic probing of dopamine receptors in drug addiction.
Current Opinion in Drug Discovery and Development.
7:703-708.
2004
|
|
| 2004
|
Role of endonuclease G in neuronal excitotoxicity in mice.
Neuroscience Letters.
364:203-207.
2004
|
|
| 2004
|
c-fos regulates neuropeptide Y expression in mouse dentate gyrus.
Neuroscience Letters.
363:6-10.
2004
|
|
| 2004
|
Cocaine-Induced Intracellular Signaling and Gene Expression Are Oppositely Regulated by the Dopamine D1 and D3 Receptors
2004
|
|
| 2004
|
Bioconductor: open software development for computational biology and bioinformatics..
Genome Biology.
5.
2004
|
|
| 2003
|
Endonuclease G is required for early embryogenesis and normal apoptosis in mice
2003
|
|
| 2003
|
Function of γ-Aminobutyric Acid Receptor/Channel ρ1 Subunits in Spinal Cord.
Journal of Biological Chemistry.
278:48321-48329.
2003
|
|
| 2003
|
7-OH-DPAT and PD 128907 selectively activate the D3 dopamine receptor in a novel environment.
Neuropsychopharmacology.
28:100-107.
2003
|
|
| 2003
|
DNA Fragmentation in Mammalian Apoptosis and Tissue Homeostasis.
Molecular Mechanisms of Programmed Cell Death.
171-183.
2003
|
|
| 2003
|
Generating gene knockout mice for studying mechanisms underlying drug addiction..
Methods in Molecular Medicine.
79:351-363.
2003
|
|
| 2002
|
Hippocampal expression of c-fos is not essential for spatial learning
2002
|
|
| 2002
|
c-fos-deficient mouse hippocampal CA3 pyramidal neurons exhibit both enhanced basal and kainic acid-induced excitability.
Neuroscience Letters.
331:151-154.
2002
|
|
| 2002
|
Expression profiles of 109 apoptosis pathway-related genes in 82 mouse tissues and experimental conditions.
Biochemical and Biophysical Research Communications.
297:537-544.
2002
|
|
| 2002
|
The dopamine D1 receptor is a critical mediator for cocaine-induced gene expression.
Journal of Neurochemistry.
82:1453-1464.
2002
|
|
| 2002
|
DNA fragmentation factor 45 knockout mice exhibit longer memory retention in the novel object recognition task compared to wild-type mice.
Physiology and Behavior.
76:315-320.
2002
|
|
| 2002
|
Apoptotic DNA fragmentation and tissue homeostasis.
Trends in Cell Biology.
12:84-89.
2002
|
|
| 2002
|
Identification of chronic cocaine-induced gene expression through dopamine D1 receptors by using cDNA microarrays.
Annals of the New York Academy of Sciences.
965:1-9.
2002
|
|
| 2002
|
c-fos regulates neuronal excitability and survival.
Nature Genetics.
30:416-420.
2002
|
|
| 2001
|
Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus.
Journal of Virology.
75:10746-10754.
2001
|
|
| 2001
|
Toward a molecular understanding of psychostimulant actions using genetically engineered dopamine receptor knockout mice as model systems.
Journal of Addictive Diseases.
20:7-18.
2001
|
|
| 2001
|
DNA fragmentation factor 45 mutant mice exhibit resistance to kainic acid-induced neuronal cell death.
Biochemical and Biophysical Research Communications.
285:1143-1149.
2001
|
|
| 2001
|
Presence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury.
Molecular Medicine.
7:205-216.
2001
|
|
| 2000
|
Lack of obvious 50 kilobase pair DNA fragments in DNA fragmentation factor 45-deficient thymocytes upon activation of apoptosis.
Biochemical and Biophysical Research Communications.
274:225-229.
2000
|
|
| 2000
|
DNA fragmentation factor 45 deficient mice exhibit enhanced spatial learning and memory compared to wild-type control mice.
Brain Research.
867:70-79.
2000
|
|
| 2000
|
Behavioral responses to cocaine and amphetamine administration in mice lacking the dopamine D1 receptor.
Brain Research.
852:198-207.
2000
|
|
| 2000
|
DNA fragmentation in apoptosis.
Cell Research.
10:205-211.
2000
|
|
| 2000
|
Probing the role of the dopamine D1 receptor in psychostimulant addiction.
Annals of the New York Academy of Sciences.
914:13-21.
2000
|
|
| 1999
|
DNA fragmentation factor 45-deficient cells are more resistant to apoptosis and exhibit different dying morphology than wild-type control cells.
Journal of Biological Chemistry.
274:37450-37454.
1999
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| 1998
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Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45
1998
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| 1996
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Intrinsic tryptophans of CRABPI as probes of structure and folding.
Protein Science.
5:1108-1117.
1996
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| 1995
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Association of an activator with an RNA polymerase II holoenzyme.
Genes and Development.
9.
1995
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| 1995
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A kinase–cyclin pair in the RNA polymerase II holoenzyme.
Nature.
374:193-196.
1995
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| 1995
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Association of an activator with an RNA polymerase II holoenzyme.
Genes and Development.
9:897-910.
1995
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| 1992
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Mutating the charged residues in the binding pocket of cellular retinoic acid‐binding protein simultaneously reduces its binding affinity to retinoic acid and increases its thermostability
1992
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