Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 TBCRC 002: A phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancer 2020
2020 miR-639 Expression Is Silenced by DNMT3A-Mediated Hypermethylation and Functions as a Tumor Suppressor in Liver Cancer Cells 2020
2020 Portable Perfusion Phantom Offers Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Accurate Prostate Cancer Grade Stratification: A Pilot Study 2020
2019 Medicaid Expansion and Hospitalization for Ambulatory Care-Sensitive Conditions among Nonelderly Adults with Diabetes 2019
2019 Lay navigation across the cancer continuum for older cancer survivors: Equally beneficial for Black and White survivors? 2019
2019 Survival Outcomes of Very Small Drug-Eluting Beads Used in Chemoembolization of Unresectable Hepatocellular Carcinoma 2019
2019 JMJD6 regulates histone H2A.X phosphorylation and promotes autophagy in triple-negative breast cancer cells via a novel tyrosine kinase activity 2019
2019 Accurate Therapeutic Response Assessment of Pancreatic Ductal Adenocarcinoma Using Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Imaging with a Point-of-Care Perfusion Phantom: A Pilot Study 2019
2019 Infection of small-bore tunneled central venous catheters 2019
2019 Lack of efficacy of high-titered immunoglobulin in patients with West Nile virus central nervous system disease 2019
2019 Urgent-start peritoneal dialysis catheter placement: Comparative study between percutaneous image-guided versus laparoscopic techniques 2019
2018 An analysis of potential predictors of tunneled hemodialysis catheter infection or dysfunction 2018
2018 An Exploration of Multilevel Physical Activity Correlates among Low-Income African Americans in Alabama and Mississippi 2018
2018 Diffusion-weighted MRI as a screening tool for hepatocellular carcinoma in cirrhotic livers: correlation with explant data—a pilot study 2018
2018 The anti-tumor effects of Mfn2 in breast cancer are dependent on promoter DNA methylation, the P21Ras motif and PKA phosphorylation site 2018
2018 Assessment of the nutrition environment in rural counties in the Deep South 2018
2017 Policy, system and environmental correlates of fruit and vegetable consumption in a low-income African American population in the southeast 2017
2017 Weight loss and improved metabolic outcomes amongst rural African American women in the Deep South: six-month outcomes from a community-based randomized trial 2017
2017 Resource use and medicare costs during lay navigation for geriatric patients with cancer 2017
2017 Implementation and Impact of Patient Lay Navigator-Led Advance Care Planning Conversations 2017
2017 MiR-10a suppresses colorectal cancer metastasis by modulating the epithelial-To-mesenchymal transition and anoikis 2017
2017 MicroRNA-20a contributes to cisplatin-resistance and migration of OVCAR3 ovarian cancer cell line 2017
2016 Phosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression 2016
2016 Mitofusin-2 is required for mouse oocyte meiotic maturation 2016
2016 KRASG12 mutant induces the release of the WSTF/NRG3 complex, and contributes to an oncogenic paracrine signaling pathway 2016
2016 The patient care connect program: Transforming health care through lay navigation 2016
2016 Inhibition of the JAK/STAT pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration 2016
2016 Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes. 2016
2016 Guiding lay navigation in geriatric patients with cancer using a distress assessment tool 2016
2016 Prognostic factors in advanced breast cancer: Race and receptor status are significant after development of metastasis 2016
2016 Uterine angiosarcoma: A case report and literature review 2016
2016 Williams syndrome transcription factor is a target of pro-oncogenic Ser158 phosphorylation mediated by Ras-MAPK pathway in human breast cancer 2016
2015 Significance of circulating tumor cells in metastatic triple-negative breast cancer patients within a randomized, phase II trial: TBCRC 019 2015
2015 TBCRC 019: A phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with triple-negative breast cancer 2015
2015 PARP1 and phospho-p65 protein expression is increased in human HER2-positive breast cancers 2015
2015 Combined therapy against recurrent and intracranial invasion of sinonasal hemangiopericytoma: A case report 2015
2015 SEMA6D expression and patient survival in breast invasive carcinoma 2015
2014 Pazopanib combined with radiation: In vivo model of interaction 2014
2014 West Nile virus neuroinvasive disease: Neurological manifestations and prospective longitudinal outcomes 2014
2014 A community-based, culturally relevant intervention to promote healthy eating and physical activity among middle-aged African American women in rural Alabama: Findings from a group randomized controlled trial 2014
2014 Assessing environmental support for better health: Active living opportunity audits in rural communities in the southern United States 2014
2014 MDM2-MOF-H4K16ac axis contributes to tumorigenesis induced by Notch 2014
2014 Predicting response and survival in chemotherapy-treated triple-negative breast cancer 2014
2014 Prognostic factors in patients with metastatic breast cancer at the time of diagnosis 2014
2014 Secretory breast carcinoma in a 12-year-old girl: A case report 2014
2014 The Impact of Breast Irradiation and Concurrent Trastuzumab on the Development of Early Cardiac Events: a Dosimetric Analysis 2014
2013 Validation of the Risk Model: High-Risk Classification and Tumor Pattern of Invasion Predict Outcome for Patients with Low-Stage Oral Cavity Squamous Cell Carcinoma 2013
2013 A phase II, randomized, open label trial of preoperative letrozole versus letrozole (LET) in combination with bevacizumab (BEV) in post-menopausal women with newly diagnosed stage II/III breast cancer 2013
2013 An open label, randomized, phase II trial of nanoparticle albumin-bound paclitaxel (nab-PAC) with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with metastatic triple negative breast cancer 2013
2013 KM method in estimation of Tumor Doubling time in Animal experiment 2013
2012 Human Papillomavirus in Non-Oropharyngeal Head and Neck Cancers: A Systematic Literature Review 2012
2012 Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity 2012
2012 Effect of anti-DR5 and chemotherapy on basal-like breast cancer 2012
2012 Hormone receptor expression and risk of recurrence in patients with high-risk endometrial carcinoma treated with chemotherapy 2012
2011 Identification of three immunologic correlates for HIV type 1 pathogenesis in Youth 2011
2011 Long-term follow-up of dose-dense neoadjuvant chemotherapy in patients with stage II/III breast cancer. 2011
2011 Breast carcinomas with isolated bone metastases have different hormone receptor expression profiles than those with metastases to other sites or multiple organs 2011
2011 Mechanisms of drug sensitization to TRA-8, an agonistic death receptor 5 antibody, involve modulation of the intrinsic apoptotic pathway in human breast cancer cells 2011
2011 Combined modality therapy with TRAIL or agonistic death receptor antibodies 2011
2011 Evaluation of the Effectiveness of Two Drugs Combination Therapy in Vitro Cytotoxicity Study 2011
2010 Clotrimazole induces a late G1 cell cycle arrest and sensitizes glioblastoma cells to radiation in vitro 2010
2010 Pilot trial of preoperative (Neoadjuvant) letrozole in combination with bevacizumab in postmenopausal women with newly diagnosed estrogen receptor-or progesterone receptor-positive breast cancer 2010
2010 Nuclear grade and survival in invasive lobular carcinoma: A case series with long-term follow-up 2010
2010 High-dimensional ROC analysis can improve the correlation between histological grade and oncotype-Dx recurrence risk in breast cancer 2010
2009 Genetic epidemiology of glioblastoma multiforme: Confirmatory and new findings from analyses of human leukocyte antigen alleles and motifs 2009
2009 Clear and independent associations of several HLA-DRB1 alleles with diVerential antibody responses to hepatitis B vaccination in youth 2009
2009 Racial disparities on glycemic control and lipid profiles in children with type 1 diabetes 2009
2008 A guided approach for personalized information search and visualization 2008
2008 FCRL2 expression predicts IGHV mutation status and clinical progression in chronic lymphocytic leukemia 2008
2007 CCL3L1 and CCL4L1: Variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection 2007
2007 Randomized controlled multicenter trial of aerosolized ribavirin for respiratory syncytial virus upper respiratory tract infection in hematopoietic cell transplant recipients 2007
2007 A Comparative Study of Diffuse Large B-Cell Lymphoma (DLBCL) between African Americans and Caucasians: Single-Center Experience at the University of Alabama at Birmingham (UAB). 2007
2007 Bayesian Statistical Power in Randomized Small Clinical Trial 2007
2007 Challenges faced by minority children in obtaining dental care 2007
2007 FCRL2 expression is predictive of IgVH mutation status and clinical progression in chronic lymphocytic leukemia 2007
2007 FCRL2 is a Novel Prognostic Marker in B Cell Chronic Lymphocytic Leukemia 2007
2007 Factors influencing lipid profiles in children with type 1 diabetes mellitus:294 2007
2006 Immune response in humans to a nasal boost with Streptococcus mutans antigens 2006
2006 Comparison of parent and student responses to asthma surveys: Students grades 1-4 and their parents from an urban public school setting 2006
2006 Regulatory challenges: Lessons from recent West Nile virus trials in the United States 2006
2006 Interleukin 18 and human immunodeficiency virus type I infection in adolescents and adults 2006
2006 Clinical Trial Design to Study Rare Infection Diseases 2006
2005 A randomized, open-label study to evaluate the safety and pharmacokinetics of human hepatitis C immune globulin (Civacir) in liver transplant recipients 2005
2005 Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiforme 2005
2004 Parameter Estimation for a proposed Joint Distribution of Correlated Bernoulli Trials 2004
2003 Restorative cost savings related to dental sealants in Alabama Medicaid children 2003
2003 Intranasal Immunization with Streptococcus Mutans Antigens: Low dose differentiates responses to soluble versus liposomal antigens 2003
2002 Disparities in dental service utilization among Alabama Medicaid children 2002
2002 Intranasal immunization with Streptococcus mutans antigens in humans with liposome as adjuvant. 2002
2001 Utilization of dental sealants by Alabama Medicaid children: barriers in meeting the year 2010 objectives. 2001
2000 Advance directives in cardiac and pulmonary rehabilitation patients 2000
1998 Preclinical pharmacology of the natural product anticancer agent 10-hydroxycamptothecin, an inhibitor of topoisomerase I 1998
1998 Intracellular Nucleotides of (-2’, 3’-deoxy-3’-thiacytidine in Peripheral Blood Mononuclear Cells of a Patient Infected with Human Immunodeficiency Virus 1998
1997 Antitumor activity and pharmacokinetics following oral administration of natural product DNA topoisomerase I inhibitors 10-hydroxycamptothecin and camptothecin in SCID mice bearing human breast cancer xenografts 1997
1996 Reversed-phase high-performance liquid chromatography method for the simultaneous quantitation of the lactone and carboxylate forms of the novel natural product anticancer agent 10-hydroxycamptothecin in biological fluids and tissues 1996
1996 Indoor and outdoor air pollution in Tokyo and Beijing supercities 1996
1993 Relationship between Trace Elements and Fluoride in Indoor Air in Endemic Fluorosis Areas 1993
1990 Research of Physical and Chemical Characteristics of Airborne Particles in Five Big Cities of China 1990
1990 Studies on Environmental Problems at the Areas of High Incidence of Lung Cancer at Xuanwei County, Yunnan Province 1990
1989 Distributions of Inorganic Anions in Different Size Airborne Particles 1989
1989 Spectrophotometer of Determination of Sulfur Dioxide with Morpholine Absorbent 1989
1988 Latest development of Liquid Chromatography (A Review) 1988

Research Overview

  • -Clinical Trials Design, Conduct and Management
    -Bayesian Method in Clinical Trial Design and Data Analysis
    -Multivariate Analysis and Statistical Modeling
    -Statistical Methods in Genome-Wide Association (GWAS) Studies
  • Principal Investigator On

    Investigator On

  • Private Grant  awarded by PROTEOGENOMICS RESEARCH INSTITUTE FOR SYSTEMS MEDICINE 2019 - 2024
  • Personalizing Immunotherapy in HER2+ Breast Cancer through Quantitative Imaging  awarded by National Cancer Institute/NIH/DHHS 2020 - 2024
  • Quantitative Imaging To Personalize Therapy in Her2 Breast Cancer  awarded by American Cancer Society, Inc. 2019 - 2022
  • Quantitative CT Biomarkers to Predict Metastatic RCC Response to Anti-Angiogenic Therapy  awarded by DOD - Department of Defense 2019 - 2021
  • 3/3 Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Morehouse School of Medicine/Tuskegee University/University of Alabama Cancer Center Partnership: Biostatistics/Bioinformatics Shared Resource  awarded by National Cancer Institute/NIH/DHHS 2016 - 2021
  • Disposable Perfusion Phantom for Accurate DCE-MRI Measurement of Pancreatic Cancer Therapy Response  awarded by National Cancer Institute/NIH/DHHS 2019 - 2021
  • The Alabama Care Plan: Assessing the Impact of Regional Care Organizations on Diabetes Outcomes in a Sample of Alabama Medicaid Recipients  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2016 - 2021
  • Private Grant  awarded by TECHNOLOGY COMMERCIALIZATION PARTNERS 2019 - 2020
  • Self-Sampling for HPV Testing in African American Women - Mississippi Delta  awarded by American Cancer Society, Inc. 2017 - 2019
  • FET-PET/MRI for Surgical Assessment of Pediatric Brain Tumors  awarded by St. Baldrick's Foundation 2017 - 2019
  • Exploiting TNBC Vulnerabilities Via Rationally Combined Therapies  awarded by American Association for Cancer Research 2015 - 2019
  • Promoting Weight-Loss in African American Cancer Survivors in the Deep South  awarded by National Cancer Institute/NIH/DHHS 2012 - 2018
  • Deep South Network for Cancer Control  awarded by National Cancer Institute/NIH/DHHS 2010 - 2017
  • UAB / UMN SPORE in Pancreatic Cancer  awarded by National Cancer Institute/NIH/DHHS 2010 - 2017
  • Private Grant  awarded by PACKHEALTH 2014 - 2016
  • Molecular Predictors of Post-Mastectomy Breast Cancer Loco-Regional Recurrence  awarded by National Cancer Institute/NIH/DHHS 2012 - 2016
  • Gulf States Collaborative Center for Health Policy Research (Gulf States CC)  awarded by BAYOU LA BATRE CLINIC 2013 - 2016
  • UAB / UMN SPORE in Pancreatic Cancer - Core C  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Active - Biostatistics and Bioinformatics - Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2013 - 2016
  • Comprehensive Cancer Center Core Support Grant  awarded by National Cancer Institute/NIH/DHHS 2011 - 2016
  • Engineered HSV for the Treatment of Malignant Glioma  awarded by National Cancer Institute/NIH/DHHS 2009 - 2015
  • Engineered HSV for the Treatment of Malignant Glioma - Core A. Administrative Core  awarded by National Cancer Institute/NIH/DHHS 2009 - 2015
  • Elevated NF-kB Signaling in Breast Cancers of African American Women  awarded by H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE 2013
  • SPORE in Breast Cancer  awarded by National Cancer Institute/NIH/DHHS 2007 - 2013
  • Death Receptor-Mediated Apoptosis and Therapy Strategies in Ovarian Cancer  awarded by National Cancer Institute/NIH/DHHS 2007 - 2013
  • Education And Training

  • Doctor of Philosophy in Biostatistics, University of Alabama at Birmingham 2003
  • Master of Science in Biostatistics, University of Alabama at Birmingham 2000
  • Master of Sciences or Mathematics in Biomedical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College 1988
  • Bachelor of Science or Mathematics in Chemistry, Nankai University 1983
  • Full Name

  • Yufeng Li
  • Fax

  • 205-934-4262