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Yuhua Song Ph.D.
Professor
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E-mail
yhsong@uab.edu
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Co-investigator Network
Yuhua Song Ph.D.
Professor
Positions
Scientist (C)
,
Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC)
,
School of Medicine
Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
Scientist
,
Cancer Cell Biology
,
O'Neal Comprehensive Cancer Center
Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
Scientist (C)
,
Neurodegeneration and Experimental Therapeutics (CNET)
,
Neurology
Professor (P)
,
Biomedical Engineering
,
School of Engineering
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
Filter
Year
Title
Altmetric
2022
Molecular and structural basis of interactions of vitamin D3 hydroxyderivatives with aryl hydrocarbon receptor (AhR): An integrated experimental and computational study
.
International Journal of Biological Macromolecules
. 209:1111-1123.
2022
2021
Vitamin D and lumisterol derivatives can act on liver X receptors (LXRs)
.
Scientific Reports
. 11.
2021
2021
In silico identification of available drugs targeting cell surface BiP to disrupt SARS-CoV-2 binding and replication: Drug repurposing approach
.
European Journal of Pharmaceutical Sciences
. 160.
2021
2020
Molecular insight for the role of key residues of calreticulin in its binding activities: A computational study
.
Computational Biology and Chemistry
. 85.
2020
2020
Molecular insights into the effect of an apoptotic raft-like bilayer on the conformation and dynamics of calreticulin
2020
2018
Calmodulin antagonist enhances DR5-mediated apoptotic signaling in TRA-8 resistant triple negative breast cancer cells
.
Journal of Cellular Biochemistry
. 119:6216-6230.
2018
2017
Activation mechanisms of αVβ3 integrin by binding to fibronectin: A computational study
.
Protein Science
. 26:1124-1137.
2017
2016
Characterization of the interactions between calmodulin and death receptor 5 in triple-negative and estrogen receptor-positive breast cancer cells: An integrated experimental and computational study
.
Journal of Biological Chemistry
. 291:12862-12870.
2016
2016
Structural Insight for Roles of DR5 Death Domain Mutations on Oligomerization of DR5 Death Domain–FADD Complex in the Death-Inducing Signaling Complex Formation: A Computational Study
.
Journal of Molecular Modeling
. 22.
2016
2014
Molecular insight into the effect of lipid bilayer environments on thrombospondin-1 and calreticulin interactions
.
Biochemistry
. 53:6309-6322.
2014
2014
Characterization of calmodulin-fas death domain interaction: An integrated experimental and computational study
.
Biochemistry
. 53:2680-2688.
2014
2013
Structural insight for the roles of fas death domain binding to fadd and oligomerization degree of the fas-fadd complex in the death-inducing signaling complex formation: A computational study
2013
2011
Effects of altered restraints in β1 integrin on the force-regulated interaction between the glycosylated I-like domain of β1 integrin and fibronectin iii
9-10
: A steered molecular dynamic study
2011
2011
Trifluoperazine regulation of calmodulin binding to Fas: A computational study
2011
2011
Cell surface engineering with polyelectrolyte multilayer thin films
.
Journal of the American Chemical Society
. 133:7054-7064.
2011
2011
Molecular and structural insight into the role of key residues of thrombospondin-1 and calreticulin in thrombospondin-1-calreticulin binding
.
Biochemistry
. 50:566-573.
2011
2010
Role of altered sialylation of the i-like domain of β1 integrin in the binding of fibronectin to β1 integrin: Thermodynamics and conformational analyses
.
Biophysical Journal
. 99:208-217.
2010
2010
Structural insight into the role of thrombospondin-1 binding to calreticulin in calreticulin-induced focal adhesion disassembly
.
Biochemistry
. 49:3685-3694.
2010
2010
Amiloride docking to acid-sensing ion channel-1
.
Journal of Biological Chemistry
. 285:9627-9635.
2010
2009
Psalmotoxin-1 docking to human acid-sensing ion channel-1
.
Journal of Biological Chemistry
. 284:17625-17633.
2009
2008
Conformation and free energy analyses of the complex of calcium-bound calmodulin and the Fas death domain
.
Biophysical Journal
. 95:5913-5921.
2008
2008
Effect of altered glycosylation on the structure of the I-like domain of β1 integrin: A molecular dynamics study
2008
2008
Molecular dynamics simulations of asymmetric NaCI and KCl solutions separated by phosphatidylcholine bilayers: Potential drops and structural changes induced by strong Na
+
-lipid interactions and finite size effects
.
Biophysical Journal
. 94:3565-3576.
2008
2007
D-periodic collagen-mimetic microfibers
.
Journal of the American Chemical Society
. 129:14780-14787.
2007
2005
Molecular dynamics simulations of salicylate effects on the micro- and mesoscopic properties of a dipalmitoylphosphatidylcholine bilayer.
.
Biochemistry
. 44:13425-13438.
2005
2004
Finite element analysis of the prestress wire-winding press
.
Journal of Materials Processing Technology
. 151:255-257.
2004
2004
A three-dimensional finite element model of the human anterior cruciate ligament: A computational analysis with experimental validation
.
Journal of Biomechanics
. 37:383-390.
2004
2004
Continuum diffusion reaction rate calculations of wild-type and mutant mouse acetylcholinesterase: Adaptive finite element analysis
.
Biophysical Journal
. 87:1558-1566.
2004
2004
Finite Element Solution of the Steady-State Smoluchowski Equation for Rate Constant Calculations
.
Biophysical Journal
. 86:2017-2029.
2004
2002
Boundary model between casting and mould and its influence on the dimensional accuracy analysis of precision castings
2002
2001
Influence of boundary model between casting and mold on the accuracy of numerical simulation of rapid tooling
2001
2001
Three dimensional non-linear coupled thermo-mechanical FEM analysis of the dimensional accuracy for casting dies in rapid tooling
.
Finite Elements in Analysis and Design
. 38:79-91.
2001
2000
Coupled thermo-mechanical analysis for plastic thermoforming
.
Polymer Engineering and Science
. 40:1736-1746.
2000
Research
Principal Investigator On
Protein Interactions Underlying Fas-Mediated DISC in Cholangiocarcinoma
awarded by
National Cancer Institute/NIH/DHHS
TREM2-Endogenous Ligand Interactions in Alzheimer Disease
awarded by
National Institute on Aging/NIH/DHHS
Thrombospondin-1/Calreticulin Binding in Regulating Cell Intermediate Adhesion and Collagen Expression
awarded by
NSF - National Science Foundation
Investigator On
E2F2 and Vascular Function
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
E2F2 and Vascular Function
awarded by
National Heart, Lung, and Blood Institute/NIH/DHHS
Human Cytosolic Sulfotransferases
awarded by
National Institute of General Medical Sciences/NIH/DHHS
Toward Therapeutic Approaches to TREM2-R47H in Alzheimer's Disease
awarded by
Alzheimer's Drug Discovery Foundation
Teaching
Teaching Activities
BME150 - Computer Meth in EGR (Fall Term 2013)
BME333 - Biomechanics of Solids (Spring Term 2008)
BME333 - Biomechanics of Solids (Spring Term 2009)
BME333 - Biomechanics of Solids (Spring Term 2010)
BME333 - Biomechanics of Solids (Spring Term 2011)
BME333 - Biomechanics of Solids (Spring Term 2012)
BME333 - Biomechanics of Solids (Spring Term 2013)
BME333 - Biomechanics of Solids (Spring Term 2014)
BME333 - Biomechanics of Solids (Spring Term 2015)
BME333 - Biomechanics of Solids (Spring Term 2016)
BME333 - Biomechanics of Solids (Spring Term 2017)
BME333 - Biomechanics of Solids (Spring Term 2018)
BME333 - Biomechanics of Solids (Spring Term 2019)
BME333 - Biomechanics of Solids (Spring Term 2020)
BME333 - Biomechanics of Solids (Spring Term 2021)
BME333 - Biomechanics of Solids (Spring Term 2022)
BME480 - Biomolecular Modelling (Fall Term 2007)
BME490 - Special Topic in BME (Spring Term 2011)
BME580 - Biomolecular Modelling (Fall Term 2007)
BME580 - Biomolecular Modelling (Fall Term 2009)
BME690 - Special Topics in (Area) (Fall Term 2015)
BME690 - Special Topics in (Area) (Fall Term 2016)
BME698 - Non-Thesis Research (Fall Term 2007)
BME698 - Non-Thesis Research (Fall Term 2008)
BME698 - Non-Thesis Research (Fall Term 2009)
BME698 - Non-Thesis Research (Fall Term 2010)
BME698 - Non-Thesis Research (Fall Term 2011)
BME698 - Non-Thesis Research (Fall Term 2012)
BME698 - Non-Thesis Research (Spring Term 2008)
BME698 - Non-Thesis Research (Spring Term 2009)
BME698 - Non-Thesis Research (Spring Term 2010)
BME698 - Non-Thesis Research (Spring Term 2011)
BME698 - Non-Thesis Research (Spring Term 2012)
BME698 - Non-Thesis Research (Spring Term 2020)
BME698 - Non-Thesis Research (Summer Term 2008)
BME698 - Non-Thesis Research (Summer Term 2009)
BME698 - Non-Thesis Research (Summer Term 2010)
BME698 - Non-Thesis Research (Summer Term 2011)
BME698 - Non-Thesis Research (Summer Term 2012)
BME698 - Non-Thesis Research (Summer Term 2020)
BME699 - Masters Thesis Research (Fall Term 2012)
BME699 - Masters Thesis Research (Spring Term 2013)
BME699 - Masters Thesis Research (Summer Term 2009)
BME699 - Masters Thesis Research (Summer Term 2013)
BME773 - Lab Rotation (Fall Term 2021)
BME780 - Biomolecular Modeling (Fall Term 2017)
BME780 - Biomolecular Modeling (Fall Term 2018)
BME780 - Biomolecular Modeling (Fall Term 2019)
BME780 - Biomolecular Modeling (Fall Term 2020)
BME780 - Biomolecular Modeling (Fall Term 2021)
BME780 - Biomolecular Modeling (Fall Term 2022)
BME790 - Special Topics in (Area) (Fall Term 2016)
BME793 - Internship in Biomedical Engin (Summer Term 2022)
BME798 - Non-Dissertation Research (Fall Term 2013)
BME798 - Non-Dissertation Research (Fall Term 2014)
BME798 - Non-Dissertation Research (Fall Term 2015)
BME798 - Non-Dissertation Research (Fall Term 2016)
BME798 - Non-Dissertation Research (Fall Term 2017)
BME798 - Non-Dissertation Research (Fall Term 2020)
BME798 - Non-Dissertation Research (Fall Term 2021)
BME798 - Non-Dissertation Research (Fall Term 2022)
BME798 - Non-Dissertation Research (Spring Term 2014)
BME798 - Non-Dissertation Research (Spring Term 2015)
BME798 - Non-Dissertation Research (Spring Term 2017)
BME798 - Non-Dissertation Research (Spring Term 2021)
BME798 - Non-Dissertation Research (Spring Term 2022)
BME798 - Non-Dissertation Research (Summer Term 2014)
BME798 - Non-Dissertation Research (Summer Term 2015)
BME798 - Non-Dissertation Research (Summer Term 2018)
BME798 - Non-Dissertation Research (Summer Term 2021)
BME798 - Non-Dissertation Research (Summer Term 2022)
BME799 - Dissertation Research (Fall Term 2016)
BME799 - Dissertation Research (Fall Term 2017)
BME799 - Dissertation Research (Fall Term 2022)
BME799 - Dissertation Research (Spring Term 2016)
BME799 - Dissertation Research (Spring Term 2017)
BME799 - Dissertation Research (Spring Term 2022)
BME799 - Dissertation Research (Summer Term 2016)
BME799 - Dissertation Research (Summer Term 2017)
BME799 - Dissertation Research (Summer Term 2022)
Background
Education And Training
Doctor of Philosophy in Materials Engineering,
Harbin Institute of Technology
1998
Master of Science in Materials Engineering,
Harbin University of Science and Technology
1996
Bachelor of Science or Mathematics in Materials Engineering,
Jilin University
1989
Contact
Full Name
Yuhua
Song