Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 New Clue: Prediction from Cell-Free DNA.Journal of Clinical Medicine.  9. 2020
2020 MeCP2 epigenetically regulates alpha-smooth muscle actin in human lung fibroblastsJournal of Cellular Biochemistry.  121:3616-3625. 2020
2020 Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged miceJCI insight.  5. 2020
2019 Inhibition of glutaminase 1 attenuates experimental pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  61:492-500. 2019
2019 Betting on novel treatments for asthma: Bromodomain 4 inhibitorsAmerican Journal of Respiratory Cell and Molecular Biology.  60:7-8. 2019
2019 Glutaminolysis epigenetically regulates antiapoptotic gene expression in idiopathic pulmonary fibrosis fibroblastsAmerican Journal of Respiratory Cell and Molecular Biology.  60:49-57. 2019
2019 HDAC inhibitors as antifibrotic drugs in cardiac and pulmonary fibrosisTherapeutic Advances in Chronic Disease.  10. 2019
2018 Glutaminolysis is required for transforming growth factor-β1-induced myofibroblast differentiation and activationJournal of Biological Chemistry.  293:1218-1228. 2018
2017 DNA methylation regulated gene expression in organ fibrosis 2017
2017 Epigenetic regulation of caveolin-1 gene expression in lung fibroblastsAmerican Journal of Respiratory Cell and Molecular Biology.  56:50-61. 2017
2016 Novel mechanisms for the antifibrotic action of nintedanibAmerican Journal of Respiratory Cell and Molecular Biology.  54:51-59. 2016
2015 SMAD-independent down-regulation of caveolin-1 by TGF-β: Effects on proliferation and survival of myofibroblastsPLoS ONE.  10. 2015
2015 Epigenetic mechanisms regulate NADPH oxidase-4 expression in cellular senescenceFree Radical Biology and Medicine.  79:197-205. 2015
2014 TGF-beta downregulation of distinct chloride channels in cystic fibrosis-affected epitheliaPLoS ONE.  9. 2014
2014 Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in miceEuropean Respiratory Journal.  43:1448-1458. 2014
2014 Reversal of persistent fibrosis in aging by targeting Nox4-Nrf2 redox imbalanceScience Translational Medicine.  6. 2014
2013 Histone deacetylase inhibition downregulates collagen 3A1 in fibrotic lung fibroblastsInternational Journal of Molecular Sciences.  14:19605-19617. 2013
2013 Histone modifications in senescence-associated resistance to apoptosis by oxidative stressRedox Biology.  1:8-16. 2013
2012 Altered DNA methylation profile in idiopathic pulmonary fibrosisAmerican Journal of Respiratory and Critical Care Medicine.  186:525-535. 2012
2012 Participation of miR-200 in pulmonary fibrosisAmerican Journal of Pathology.  180:484-493. 2012
2011 Absence of Thy-1 results in TGF-Β induced MMP-9 expression and confers a profibrotic phenotype to human lung fibroblastsLaboratory Investigation.  91:1206-1218. 2011
2011 Epigenetic regulation of Thy-1 by histone deacetylase inhibitor in rat lung fibroblastsAmerican Journal of Respiratory Cell and Molecular Biology.  45:16-23. 2011
2008 Thy-1 promoter hypermethylation: A novel epigenetic pathogenic mechanism in pulmonary fibrosisAmerican Journal of Respiratory Cell and Molecular Biology.  39:610-618. 2008
2007 Enhanced myofibroblastic differentiation and survival in thy-1(-) lung fibroblastsAmerican Journal of Respiratory Cell and Molecular Biology.  36:226-235. 2007
2002 Increased expression of heterogeneous nuclear ribonucleoprotein A2/B1 (hnRNP) in pancreatic tissue from smokers and pancreatic tumor cells.Cancer Letters.  183:215-220. 2002
2001 Specific site methylation in the 5'-flanking region of CYP1A2 interindividual differences in human livers.Life Sciences.  69:839-845. 2001

Chapter

Year Title Altmetric
2014 Signaling Networks Controlling Cellular Senescence.  67-83. 2014

Education And Training

  • Doctor of Medicine in Pediatrics Residency Program, Central South University 1992
  • Full Name

  • Yan Sanders