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Hui Xu Ph.D.
Professor
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E-mail
xuhui@uab.edu
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Hui Xu Ph.D.
Professor
Positions
Senior Scientist (C)
,
Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC)
,
School of Medicine
Senior Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
Professor (P)
,
Dermatology
,
School of Medicine
Assistant Professor - Research (S)
,
Pathology
,
Academic Joint Departments
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
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2020
Expert consensus workshop report: Guidelines for thermal ablation of thyroid tumors (2019 edition)
.
Journal of Cancer Research and Therapeutics
. 16:960-966.
2020
2020
PDX regulates inflammatory cell infiltration via resident macrophage in LPS-induced lung injury
.
Journal of Cellular and Molecular Medicine
. 24:10604-10614.
2020
2019
CD5 on dendritic cells regulates CD4+ and CD8+ T cell activation and induction of immune responses
.
PLoS ONE
. 14.
2019
2018
Differential and overlapping effects of 20,23(OH)
2
D3 and 1,25(OH)
2
D3 on gene expression in human epidermal keratinocytes: Identification of AHR as an alternative receptor for 20,23(OH)
2
D3
.
International Journal of Molecular Sciences
. 19.
2018
2018
Identifying potential quality markers of Xin-Su-Ning capsules acting on arrhythmia by integrating UHPLC-LTQ-Orbitrap, ADME prediction and network target analysis.
.
Phytomedicine
. 44:117-128.
2018
2017
Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1
+/−
/SKH-1 Hairless Mice
.
Photochemistry and Photobiology
. 93:1016-1024.
2017
2015
In vivo suppression of heat shock protein (HSP)27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemical
.
Journal of Immunology
. 194:4796-4803.
2015
2015
Interleukin-17 mediated inflammatory responses are required for ultraviolet radiation-induced immune suppression
.
Photochemistry and Photobiology
. 91:235-241.
2015
2013
Interleukin-3 plays dual roles in osteoclastogenesis by promoting the development of osteoclast progenitors but inhibiting the osteoclastogenic process
.
Biochemical and Biophysical Research Communications
. 440:545-550.
2013
2013
Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cells
.
Biochemical Pharmacology
. 85:1066-1076.
2013
2013
Bioactive grape proanthocyanidins enhance immune reactivity in UV-irradiated skin through functional activation of dendritic cells in mice
.
Cancer Prevention Research
. 6:242-252.
2013
2012
IL-17 mediated inflammation promotes tumor growth and progression in the skin
.
PLoS ONE
. 7.
2012
2012
UVB immunosuppression: Vitamin D or not vitamin D? That is the question
.
Journal of Investigative Dermatology
. 132:2676-2678.
2012
2011
Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by Toll-like receptor-4
.
Archives of Biochemistry and Biophysics
. 508:171-177.
2011
2011
Proanthocyanidins inhibit UV-induced immunosuppression through IL-12-dependent stimulation of CD8
+
effector T cells and inactivation of CD4
+
T cells
.
Cancer Prevention Research
. 4:238-247.
2011
2009
IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammation
.
Carcinogenesis
. 30:1970-1977.
2009
2009
IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responses
.
Journal of Immunology
. 183:1463-1470.
2009
2008
Antagonistic roles of CD4
+
and CD8
+
T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis
.
Cancer Research
. 68:3924-3930.
2008
2008
Protective role of toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis
.
Cancer Research
. 68:615-622.
2008
2008
Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinoma
.
Neoplasia
. 10:1411-1420.
2008
2007
Acquired and innate immunity to polyaromatic hydrocarbons
.
Toxicology and Applied Pharmacology
. 224:308-312.
2007
2006
CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses.
.
Journal of Immunology
. 177:6852-6858.
2006
2004
Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4
+
and CD8
+
T lymphocytes
.
International Immunology
. 16:345-351.
2004
2003
Neuronal Repellent Slit2 Inhibits Dendritic Cell Migration and the Development of Immune Responses
.
Journal of Immunology
. 171:6519-6526.
2003
2001
Host defense mechanisms in polyaromatic hydrocarbon carcinogenesis
.
Skin Pharmacology and Applied Skin Physiology
. 14:386-392.
2001
2001
The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node
.
European Journal of Immunology
. 31:3085-3093.
2001
2001
The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node.
.
European Journal of Immunology
. 31:3085-3093.
2001
2000
Negative regulation of CD8
+
T cell function by the IFN-induced and double-stranded RNA-activated kinase PKR
.
Journal of Immunology
. 165:6896-6901.
2000
2000
Sensitization versus elicitation in allergic contact dermatitis: Potential differences at cellular and molecular levels
.
Dermatitis
. 11:228-234.
2000
1999
Immunosuppressive effects of silicon phthalocyanine photodynamic therapy
.
Photochemistry and Photobiology
. 70:72-77.
1999
1998
Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complex
1998
1996
Diversion of CD4
+
T cell development from regulatory T helper to effector T helper cells alters the contact hypersensitivity response
.
European Journal of Immunology
. 26:2606-2612.
1996
1996
Interferon-γ inducible protein (IP-10) expression is mediated by CD8
+
T cells and is regulated by CD4
+
T cells during the elicitation of contact hypersensitivity
.
Journal of Investigative Dermatology
. 107:360-366.
1996
Chapter
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Year
Title
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2013
Host defenses in the skin
. 228-238.
2013
Research
Principal Investigator On
Allergic Contact Dermatitis: Mechanisms of Elicitation
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
Collaboration Agreement (Research application of the B6.Cg-Il17atm1.1(EYFP/cre)Ehs Gt(ROSA) 26Sortm9(CAG-tdTomato)Hze Tg(TcraTcrb)425Cbn mice)
awarded by
NIH - National Institutes of Health/DHHS
Mechanism of Ultraviolet Radiation Induced Immune Tolerance
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
Mechanisms of Ultraviolet Radiation Induced Immune Suppression
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
The Role of CD5 in Dendritic Cell Mediated Immune Suppression
awarded by
National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS
The Role of IL-17 Producing T Lymphocytes in Allergic Contact Dermatitis
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Investigator On
Blocking Arsenicals-Induced Cutaneous Injury
awarded by
National Institute of Neurological Disorders and Stroke/NIH/DHHS
Prevention of UV-Carcinogenesis through DNA Repair-Dependent Immunomodulation
awarded by
National Cancer Institute/NIH/DHHS
Role of Trem1 in Ultraviolet Radiation-Induced Immune Suppression
awarded by
National Institute of Allergy and Infectious Diseases/NIH/DHHS
Background
Education And Training
Doctor of Philosophy Level Degree in Immunology,
1992
Master of Science in Immunology,
Tongji University
1986
Bachelor of Science or Mathematics in Medicine,
Wuhan University of Science and Technology
1980
Awards And Honors
Visiting Scholarship
,
1988
Contact
Full Name
Hui
Xu