Selected Publications

Academic Article

Year Title Altmetric
2019 CD5 on dendritic cells regulates CD4+ and CD8+ T cell activation and induction of immune responsesPLoS ONE.  14. 2019
2018 Differential and overlapping effects of 20,23(OH)2 D3 and 1,25(OH)2 D3 on gene expression in human epidermal keratinocytes: Identification of AHR as an alternative receptor for 20,23(OH)2 D3International Journal of Molecular Sciences.  19. 2018
2017 Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1+/−/SKH-1 Hairless MicePhotochemistry and Photobiology.  93:1016-1024. 2017
2015 In vivo suppression of heat shock protein (HSP)27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemicalJournal of Immunology.  194:4796-4803. 2015
2015 Interleukin-17 mediated inflammatory responses are required for ultraviolet radiation-induced immune suppressionPhotochemistry and Photobiology.  91:235-241. 2015
2013 Interleukin-3 plays dual roles in osteoclastogenesis by promoting the development of osteoclast progenitors but inhibiting the osteoclastogenic processJournal of Healthcare Leadership.  440:545-550. 2013
2013 Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cellsInformation, Communication and Society.  85:1066-1076. 2013
2013 Bioactive grape proanthocyanidins enhance immune reactivity in UV-irradiated skin through functional activation of dendritic cells in miceJournal of Public Health Management & Practice.  6:242-252. 2013
2012 IL-17 mediated inflammation promotes tumor growth and progression in the skinPLoS ONE.  7. 2012
2012 UVB immunosuppression: Vitamin D or not vitamin D? That is the questionJournal of Investigative Dermatology.  132:2676-2678. 2012
2011 Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by Toll-like receptor-4Heliyon.  508:171-177. 2011
2011 Proanthocyanidins inhibit UV-induced immunosuppression through IL-12-dependent stimulation of CD8 + effector T cells and inactivation of CD4 + T cellsJournal of Public Health Management & Practice.  4:238-247. 2011
2009 IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammationJournal of Autoimmunity.  30:1970-1977. 2009
2009 IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responsesJournal of Immunology.  183:1463-1470. 2009
2008 Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesisCurrent Protocols in Toxicology.  68:3924-3930. 2008
2008 Protective role of toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesisCurrent Protocols in Toxicology.  68:615-622. 2008
2008 Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinomaNeoplasia : An International Journal for Oncology Research.  10:1411-1420. 2008
2007 Acquired and innate immunity to polyaromatic hydrocarbonsToxicology and Applied Pharmacology.  224:308-312. 2007
2006 CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses.Journal of Immunology.  177:6852-6858. 2006
2004 Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytesInternational Immunology.  16:345-351. 2004
2003 Neuronal Repellent Slit2 Inhibits Dendritic Cell Migration and the Development of Immune ResponsesJournal of Immunology.  171:6519-6526. 2003
2001 Host defense mechanisms in polyaromatic hydrocarbon carcinogenesisSkin Pharmacology and Applied Skin Physiology.  14:386-392. 2001
2001 The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph nodeEuropean Journal of Immunology.  31:3085-3093. 2001
2001 The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node.European Journal of Immunology.  31:3085-3093. 2001
2000 Sensitization versus elicitation in allergic contact dermatitis: Potential differences at cellular and molecular levelsTexas Public Health Association Journal.  11:228-234. 2000
1999 Immunosuppressive effects of silicon phthalocyanine photodynamic therapyPhotochemistry and Photobiology.  70:72-77. 1999
1998 Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complexProceedings of the National Academy of Sciences.  95:14915-14919. 1998


Year Title Altmetric
2013 Host defenses in the skin.  228-238. 2013

Education And Training

  • Doctor of Philosophy Level Degree in Immunology, 1992
  • Master of Science in Immunology, Tongji University 1986
  • Bachelor of Science or Mathematics in Medicine, Wuhan University of Science and Technology 1980
  • Awards And Honors

    Full Name

  • Hui Xu