Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 CD5 on dendritic cells regulates CD4+ and CD8+ T cell activation and induction of immune responsesPLoS ONE.  14. 2019
2018 Differential and overlapping effects of 20,23(OH)2 D3 and 1,25(OH)2 D3 on gene expression in human epidermal keratinocytes: Identification of AHR as an alternative receptor for 20,23(OH)2 D3International Journal of Molecular Sciences.  19. 2018
2017 Naproxen Inhibits UVB-induced Basal Cell and Squamous Cell Carcinoma Development in Ptch1+/−/SKH-1 Hairless MicePhotochemistry and Photobiology.  93:1016-1024. 2017
2015 In vivo suppression of heat shock protein (HSP)27 and HSP70 accelerates DMBA-induced skin carcinogenesis by inducing antigenic unresponsiveness to the initiating carcinogenic chemicalJournal of Immunology.  194:4796-4803. 2015
2015 Interleukin-17 mediated inflammatory responses are required for ultraviolet radiation-induced immune suppressionPhotochemistry and Photobiology.  91:235-241. 2015
2013 Interleukin-3 plays dual roles in osteoclastogenesis by promoting the development of osteoclast progenitors but inhibiting the osteoclastogenic processBiochemical and Biophysical Research Communications.  440:545-550. 2013
2013 Silymarin inhibits ultraviolet radiation-induced immune suppression through DNA repair-dependent activation of dendritic cells and stimulation of effector T cellsBiochemical Pharmacology.  85:1066-1076. 2013
2013 Bioactive grape proanthocyanidins enhance immune reactivity in UV-irradiated skin through functional activation of dendritic cells in miceCancer Prevention Research.  6:242-252. 2013
2012 IL-17 mediated inflammation promotes tumor growth and progression in the skinPLoS ONE.  7. 2012
2012 UVB immunosuppression: Vitamin D or not vitamin D? That is the questionJournal of Investigative Dermatology.  132:2676-2678. 2012
2011 Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by Toll-like receptor-4Archives of Biochemistry and Biophysics.  508:171-177. 2011
2011 Proanthocyanidins inhibit UV-induced immunosuppression through IL-12-dependent stimulation of CD8 + effector T cells and inactivation of CD4 + T cellsCancer Prevention Research.  4:238-247. 2011
2009 IL-12 deficiency suppresses 12-O-tetradecanoylphorbol-13-acetate-induced skin tumor development in 7,12-dimethylbenz(a)anthracene-initiated mouse skin through inhibition of inflammationCarcinogenesis.  30:1970-1977. 2009
2009 IL-17 and IFN-γ mediate the elicitation of contact hypersensitivity responses by different mechanisms and both are required for optimal responsesJournal of Immunology.  183:1463-1470. 2009
2008 Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesisCancer Research.  68:3924-3930. 2008
2008 Protective role of toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesisCancer Research.  68:615-622. 2008
2008 Slit2 inhibits growth and metastasis of fibrosarcoma and squamous cell carcinomaNeoplasia.  10:1411-1420. 2008
2007 Acquired and innate immunity to polyaromatic hydrocarbonsToxicology and Applied Pharmacology.  224:308-312. 2007
2006 CD8+ IL-17-producing T cells are important in effector functions for the elicitation of contact hypersensitivity responses.Journal of Immunology.  177:6852-6858. 2006
2004 Development of dermatitis in CD18-deficient PL/J mice is not dependent on bacterial flora, and requires both CD4+ and CD8+ T lymphocytesInternational Immunology.  16:345-351. 2004
2003 Neuronal Repellent Slit2 Inhibits Dendritic Cell Migration and the Development of Immune ResponsesJournal of Immunology.  171:6519-6526. 2003
2001 Host defense mechanisms in polyaromatic hydrocarbon carcinogenesisSkin Pharmacology and Applied Skin Physiology.  14:386-392. 2001
2001 The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph nodeEuropean Journal of Immunology.  31:3085-3093. 2001
2001 The role of ICAM-1 molecule in the migration of Langerhans cells in the skin and regional lymph node.European Journal of Immunology.  31:3085-3093. 2001
2000 Sensitization versus elicitation in allergic contact dermatitis: Potential differences at cellular and molecular levelsDermatitis.  11:228-234. 2000
1999 Immunosuppressive effects of silicon phthalocyanine photodynamic therapyPhotochemistry and Photobiology.  70:72-77. 1999
1998 Susceptibility to the biological effects of polyaromatic hydrocarbons is influenced by genes of the major histocompatibility complex 1998

Chapter

Year Title Altmetric
2013 Host defenses in the skin.  228-238. 2013

Education And Training

  • Doctor of Philosophy Level Degree in Immunology, 1992
  • Master of Science in Immunology, Tongji University 1986
  • Bachelor of Science or Mathematics in Medicine, Wuhan University of Science and Technology 1980
  • Awards And Honors

    Full Name

  • Hui Xu