Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis.  Journal of Neuro-Oncology.  141:289-301. 2019
2018 Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression.  Scientific Reports.  8. 2018
2017 Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells.  Stem Cell Reports.  9:1604-1617. 2017
2017 Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells 2017
2017 Recovery of methotrexate-induced anuric acute kidney injury after glucarpidase therapy..  SAGE Open Medical Case Reports.  5:2050313X17705050. 2017
2016 A randomized phase II trial of standard dose bevacizumab versus low dose bevacizumab plus lomustine (CCNU) in adults with recurrent glioblastoma.  Journal of Neuro-Oncology.  129:487-494. 2016
2016 Neuronal Wiskott-Aldrich syndrome protein regulates TGF-β1-mediated lung vascular permeability.  The FASEB Journal.  30:2557-2569. 2016
2016 Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis..  Neuro-Oncology.  18:830-839. 2016
2016 Acute disseminated encephalomyelitis presenting as a brainstem encephalitis.  Clinical Neurology and Neurosurgery.  143:76-79. 2016
2016 Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses.  Neuro-Oncology.  18:227-235. 2016
2015 Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomas.  Journal of Neuro-Oncology.  122:585-593. 2015
2014 Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro.  Journal of Neuro-Oncology.  118:61-72. 2014
2014 The role of Src family kinases in growth and migration of glioma stem cells.  International Journal of Oncology.  45:302-310. 2014
2014 Transcription start site sequence and spacing between the -10 region and the start site affect reiterative transcription-mediated regulation of gene expression in Escherichia coli.  Journal of Bacteriology.  196:2912-2920. 2014
2003 The genomic sequence of ectromelia virus, the causative agent of mousepox.  Virology.  317:165-186. 2003
2002 Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: Differences in integrin signaling during cell adhesion to osteopontin versus vitronectin.  Cancer Research.  62:5336-5343. 2002

Research Overview

  • Glioblastoma
    Low Grade Glioma
    Oligodendroglioma
    Astrocytome

    • Education And Training

  • Doctor of Philosophy in Medical Microbiology, University of Alabama at Birmingham 1998
  • Doctor of Medicine, 1987
  • UAB Hospital, Internship 2005
  • UAB Hospital, Residency 2008
  • MD Anderson Cancer Center, Postdoctoral Fellowship 2009

    • Full Name

  • Xiaosi Han