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Xiaosi Han
Associate Professor
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xhan@uab.edu
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Xiaosi Han
Associate Professor
Positions
Scientist
,
Neuro-Oncology
,
O'Neal Comprehensive Cancer Center
Associate Professor (P)
,
Neurology
,
School of Medicine
2009 -
Associate Scientist (C)
,
Center for Clinical and Translational Science (CCTS)
,
General Clinical Research Center
2009 -
Associate Scientist (C)
,
Comprehensive Neuroscience Center
,
General Clinical Research Center
2011 -
Scientist (C)
,
O'Neal Comprehensive Cancer Center
,
School of Medicine
2019 -
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
Altmetric
2019
Characterization of iPSCs derived from low grade gliomas revealed early regional chromosomal amplifications during gliomagenesis
.
Journal of Neuro-Oncology
. 141:289-301.
2019
2018
Enhanced Sensitivity of Patient-Derived Pediatric High-Grade Brain Tumor Xenografts to Oncolytic HSV-1 Virotherapy Correlates with Nectin-1 Expression
.
Scientific Reports
. 8.
2018
2017
Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells
.
Stem Cell Reports
. 9:1604-1617.
2017
2017
Canonical microRNAs Enable Differentiation, Protect Against DNA Damage, and Promote Cholesterol Biosynthesis in Neural Stem Cells
2017
2017
Recovery of methotrexate-induced anuric acute kidney injury after glucarpidase therapy.
.
SAGE Open Medical Case Reports
. 5:2050313X17705050.
2017
2016
A randomized phase II trial of standard dose bevacizumab versus low dose bevacizumab plus lomustine (CCNU) in adults with recurrent glioblastoma
.
Journal of Neuro-Oncology
. 129:487-494.
2016
2016
Neuronal Wiskott-Aldrich syndrome protein regulates TGF-β1-mediated lung vascular permeability
.
The FASEB Journal
. 30:2557-2569.
2016
2016
Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis.
.
Neuro-Oncology
. 18:830-839.
2016
2016
Acute disseminated encephalomyelitis presenting as a brainstem encephalitis
.
Clinical Neurology and Neurosurgery
. 143:76-79.
2016
2016
Pediatric medulloblastoma xenografts including molecular subgroup 3 and CD133+ and CD15+ cells are sensitive to killing by oncolytic herpes simplex viruses
.
Neuro-Oncology
. 18:227-235.
2016
2015
Prolonged treatment with bevacizumab is associated with brain atrophy: a pilot study in patients with high-grade gliomas
.
Journal of Neuro-Oncology
. 122:585-593.
2015
2014
Expression of PRMT5 correlates with malignant grade in gliomas and plays a pivotal role in tumor growth in vitro
.
Journal of Neuro-Oncology
. 118:61-72.
2014
2014
The role of Src family kinases in growth and migration of glioma stem cells
.
International Journal of Oncology
. 45:302-310.
2014
2014
Transcription start site sequence and spacing between the -10 region and the start site affect reiterative transcription-mediated regulation of gene expression in Escherichia coli
.
Journal of Bacteriology
. 196:2912-2920.
2014
2003
The genomic sequence of ectromelia virus, the causative agent of mousepox
.
Virology
. 317:165-186.
2003
2002
Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: Differences in integrin signaling during cell adhesion to osteopontin versus vitronectin
.
Cancer Research
. 62:5336-5343.
2002
Research
Research Overview
Glioblastoma
Low Grade Glioma
Oligodendroglioma
Astrocytome
Background
Education And Training
Doctor of Philosophy in Medical Microbiology,
University of Alabama at Birmingham
1998
Doctor of Medicine,
1987
UAB Hospital, Internship
2005
UAB Hospital, Residency
2008
MD Anderson Cancer Center, Postdoctoral Fellowship
2009
Contact
Full Name
Xiaosi
Han