Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Avian erythroblastosis virus E26 oncogene homolog-1 (ETS-1) plays a role in renal microvascular pathophysiology in the Dahl salt-sensitive ratKidney International.  97:528-537. 2020
2020 COX-2-derived prostaglandins as mediators of the deleterious effects of nicotine in chronic kidney disease 2020
2019 Ferritin light chain confers protection against sepsis-induced inflammation and organ injuryFrontiers in Immunology.  10. 2019
2019 Immunoglobulin light chains generate proinflammatory and profibrotic kidney injuryJournal of Clinical Investigation.  129:2792-2806. 2019
2019 Induced pluripotent stem cell-derived endothelial cells attenuate lipopolysaccharide-induced acute lung injury 2019
2018 Cutaneous exposure to lewisite causes acute kidney injury by invoking dna damage and autophagic response 2018
2017 Haploinsufficiency of the Transcription Factor Ets-1 Is renoprotective in dahl salt-sensitive ratsJournal of the American Society of Nephrology.  28:3239-3250. 2017
2017 Novel paradigms of salt and hypertensionJournal of the American Society of Nephrology.  28:1362-1369. 2017
2015 Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake 2015
2015 Transcription factor avian erythroblastosis virus E26 oncogen homolog-1 is a novel mediator of renal injury in salt-sensitive hypertensionHypertension.  65:813-820. 2015
2014 The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistulaJournal of the American Society of Nephrology.  25:475-487. 2014
2012 Role of the transcription factor erythroblastosis virus E26 oncogen homolog-1 (ETS-1) as mediator of the renal proinflammatory and profibrotic effects of angiotensin IIHypertension.  60:1226-1233. 2012
2012 Nicotine exposure and the progression of chronic kidney disease: Role of the α7-nicotinic acetylcholine receptor 2012
2012 Estrogen modulates NFκB signaling by enhancing IκBα levels and blocking p65 binding at the promoters of inflammatory genes via estrogen receptor-βPLoS ONE.  7. 2012
2012 The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells 2012
2012 Cardiomyopathy and response to enzyme replacement therapy in a male mouse model for fabry diseasePLoS ONE.  7. 2012
2011 O-GlcNAc modification of nfκb p65 inhibits tnf-α-induced inflammatory mediator expression in rat aortic smooth muscle cellsPLoS ONE.  6. 2011
2011 Environmental tobacco smoke furthers progression of diabetic nephropathyAmerican Journal of the Medical Sciences.  341:126-130. 2011
2010 Nicotine worsens the severity of nephropathy in diabetic mice: Implications for the progression of kidney disease in smokers 2010
2010 The transcription factor ETS-1 mediates proinflammatory responses and neointima formation in carotid artery endoluminal vascular injuryHypertension.  55:1381-1388. 2010
2008 Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury 2008
2008 Aging leads to increased levels of protein O-linked N-acetylglucosamine in heart, aorta, brain and skeletal muscle in Brown-Norway ratsBiogerontology.  9:139-151. 2008
2008 Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (FcγRI)-dependentAmerican Journal of Pathology.  172:22-30. 2008
2007 Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation 2007
2007 Aged rats lose vasoprotective and anti-inflammatory actions of estrogen in injured arteries 2007
2005 Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice 2005
2005 Cholangiocyte endothelin 1 and transforming growth factor β1 production in rat experimental hepatopulmonary syndromeGastroenterology.  129:682-695. 2005
2004 Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells 2004
2004 Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteriesCirculation.  110:1664-1669. 2004
2003 Hormone replacement therapy and inflammation: Interactions in cardiovascular diseaseHypertension.  42:657-663. 2003

Research Overview

  • Mechanisms of Hypertensive Nephrolpathy
  • Education And Training

  • Doctor of Philosophy in Physiology, Pathology and Related Sciences, 1996
  • Doctor of Medicine, 1989
  • Full Name

  • Wenguang Feng