Positions

Overview

  • William W. Andrews, PhD, MD, is from Dale County, Alabama. He received his undergraduate degree from Auburn University, 1974, and completed his PhD in Physiology, 1980, (Reproductive Neuroendocrinology) from The Graduate School of Biomedical Sciences, Southwestern Medical Center. Dr. Andrews received his MD degree, cum laude, from University of Alabama School of Medicine, 1984. He obtained his residency training at University Hospital, 1988, where he received Best Senior Resident Research Presentation Award and Best Teaching Chief Resident Award. He then moved to Dallas, Texas where he completed fellowship training in Maternal-Fetal Medicine before returning to the UASOM Department of Obstetrics and Gynecology as an Assistant Professor in 1990. He has held the Charles E. Flowers, Jr. Endowed Chair in OB/GYN since September of 2009.

    Following these accomplishments, Dr. Andrews established a Maternal-Fetal Cohort of Preterm Infants, and the ability to evaluate the impact of the profound preterm state on long-term neurodevelopment by six years of age. This application was funded from the NICHD, via Perinatal Emphasis Research Center (PERC) grant and an R01 grant. Dr. Andrews conducted and participated in many clinical research trials and several research networks. He is nationally recognized for his excellent research accomplishments in the field of OB/GYN Clinical Obstetrics and Prematurity. His research has been primarily focused on preterm birth and prevention, concentrating on infection and inflammation as potential diagnosis of involuntary preterm birth.

    Dr. Andrews has displayed excellent leadership at UAB as Professor and Chair of the Department of Obstetrics and Gynecology, a position he has held for over six years. He is one of the top faculty members at UAB and is a part of many University and UASOM committees. He established the UAB Laboratory for Research in Women’s Health to provide patients with the most up-to-date, knowledgeable, and preventive medical care available. Dr. Andrews exhibits high quality characteristics of research, maternal-fetal clinical care, and education at UAB’s School of Medicine. He is known for showing compassion and support for his faculty, residents, students and staff, as well as contributing to the excellence of resident and student education.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Azithromycin-based Extended-Spectrum Antibiotic Prophylaxis for Cesarean: Role of Placental Colonization with Genital Ureaplasmas and MycoplasmasAmerican Journal of Perinatology.  36:1002-1008. 2019
    2019 Evaluating Fundal Dominant Contractions on Spatiotemporal Electrohysterography as a Marker for Effective Labor ContractionsAmerican Journal of Perinatology.  36:924-929. 2019
    2019 Impact of Azithromycin-Based Extended-Spectrum Antibiotic Prophylaxis on Noninfectious Cesarean Wound ComplicationsAmerican Journal of Perinatology.  36:886-890. 2019
    2019 Incidence and Risk Factors for Hospital Readmission or Unexpected Visits in Women Undergoing Unscheduled Cesarean DeliveryAmerican Journal of Perinatology.  36:1115-1119. 2019
    2018 Cervical funneling or intra-amniotic debris and preterm birth in nulliparous women with midtrimester cervical length less than 30 mmUltrasound in Obstetrics and Gynaecology.  52:757-762. 2018
    2018 Pharmacogenomics of 17-alpha hydroxyprogesterone caproate for recurrent preterm birth: a case–control studyBJOG: An International Journal of Obstetrics and Gynaecology.  125:343-350. 2018
    2018 Defining failed induction of laborAmerican Journal of Obstetrics and Gynecology.  218:122.e1-122.e8. 2018
    2018 Institutional protocols for vaginal preparation with antiseptic solution and surgical site infection rate in women undergoing cesarean delivery during laborObstetrics and Gynecology.  132:371-376. 2018
    2017 The association among cytochrome P450 3A, progesterone receptor polymorphisms, plasma 17-alpha hydroxyprogesterone caproate concentrations, and spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  217:369.e1-369.e9. 2017
    2017 Economic Evaluation of Adjunctive Azithromycin Prophylaxis for Cesarean DeliveryObstetrics and Gynecology.  130:328-334. 2017
    2017 Onset of human preterm and term birth is related to unique inflammatory transcriptome profiles at the maternal fetal interfacePeerJ.  2017. 2017
    2017 Risk factors for postcesarean maternal infection in a trial of extended-spectrum antibiotic prophylaxisObstetrics and Gynecology.  129:481-485. 2017
    2016 Adjunctive azithromycin prophylaxis for cesarean deliveryNew England Journal of Medicine.  375:1231-1241. 2016
    2016 Influenza vaccination and antiviral therapy in pregnant womenJournal of Infectious Diseases.  214:505-506. 2016
    2016 Preterm neonatal morbidity and mortality by gestational age: A contemporary cohortAmerican Journal of Obstetrics and Gynecology.  215:103.e1-103.e14. 2016
    2016 Infection and preterm birthSeminars in Neonatology..  21:100-105. 2016
    2016 Predictors of response to 17-alpha hydroxyprogesterone caproate for prevention of recurrent spontaneous preterm birth Presented in part as a poster presentation at the 35th Annual Society of Maternal Fetal Medicine Meeting, San Diego, CA, February 2-7, 2015.American Journal of Obstetrics and Gynecology.  214:376.e1-376.e8. 2016
    2016 Wound morbidity with staples compared with suture for cesarean skin closure by diabetic statusJournal of Maternal-Fetal and Neonatal Medicine.  29:279-282. 2016
    2015 Serious maternal complications after early preterm delivery (24-33 weeks' gestation)American Journal of Obstetrics and Gynecology.  213. 2015
    2015 Use and attitudes of obstetricians toward 3 high-risk interventions in MFMU Network hospitalsAmerican Journal of Obstetrics and Gynecology.  213:398.e1-398.e11. 2015
    2015 The phenotype of spontaneous preterm birth: Application of a clinical phenotyping toolAmerican Journal of Obstetrics and Gynecology.  212:487.e1-487.e11. 2015
    2015 A Genome-Wide Association Study of Early Spontaneous Preterm DeliveryGenetic Epidemiology.  39:217-226. 2015
    2015 What is new in stillbirth?: important recent articlesObstetrics and Gynecology.  125:160-161. 2015
    2014 Maternal serum serpin B7 is associated with early spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  211:678.e1-678.e12. 2014
    2014 Epidural Use and Clinical Chorioamnionitis among Women Who Delivered VaginallyAmerican Journal of Perinatology.  31:1009-1014. 2014
    2014 Predicting fetal acidemia using umbilical venous cord gas parametersObstetrics and Gynecology.  124:926-932. 2014
    2014 Risk of adverse pregnancy outcomes in women with mild chronic hypertension before 20 weeks of gestationObstetrics and Gynecology.  123:966-972. 2014
    2013 Selective uptake of influenza vaccine and pregnancy outcomesJournal of Maternal-Fetal and Neonatal Medicine.  26:1207-1211. 2013
    2013 Erratum: Surgical staples compared with subcuticular suture for skin closure after cesarean delivery: A randomized controlled trial (Obstetrics and Gynecology (2013) 121 (33-8))Obstetrics and Gynecology.  121:1113. 2013
    2013 Cesarean delivery for refractory status asthmaticusObstetrics and Gynecology.  121:417-418. 2013
    2013 Effect of corticosteroid interval on markers of inflammation in spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  209:379.e1-379.e6. 2013
    2013 Surgical staples compared with subcuticular suture for skin closure after cesarean delivery: A randomized controlled trialObstetrics and Gynecology.  121:33-38. 2013
    2013 What is new in preterm birth prevention? Important recent articles.Obstetrics and Gynecology.  122:390-392. 2013
    2012 Elevated midtrimester α-fetoprotein and delivery markers of inflammation in a preterm populationJournal of Maternal-Fetal and Neonatal Medicine.  25:2424-2427. 2012
    2012 Antibiotic prophylaxis for cesarean delivery: Survey of maternal-fetal medicine physicians in the U.S.Journal of Maternal-Fetal and Neonatal Medicine.  25:1264-1266. 2012
    2012 Child intellectual development in relation to cytokine levels in umbilical cord bloodAmerican Journal of Epidemiology.  175:1191-1199. 2012
    2012 Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestationObstetrical and Gynecological Survey.  67:215-217. 2012
    2012 Antimicrobials for preterm birth prevention: An overviewInfectious Diseases in Obstetrics & Gynecology.  2012. 2012
    2012 Higher-dose oxytocin and hemorrhage after vaginal delivery: A randomized controlled trialObstetrics and Gynecology.  119:293-300. 2012
    2011 Association of antenatal corticosteroids with mortality and neurodevelopmental outcomes among infants born at 22 to 25 weeks' gestationJournal of the American Medical Association.  306:2348-2358. 2011
    2011 Bacterial vaginosis is associated with variation in dietary indicesJournal of Nutrition.  141:1698-1704. 2011
    2011 Effect of antibiotic exposure on nugent score among pregnant women with and without bacterial vaginosisObstetrics and Gynecology.  117:844-849. 2011
    2010 Bacterial vaginosis assessed by Gram stain and diminished colonization resistance to incident gonococcal, chlamydial, and trichomonal genital infectionJournal of Infectious Diseases.  202:1907-1915. 2010
    2010 Association between periodontal disease, bacterial vaginosis, and sexual risk behavioursJournal of Clinical Periodontology.  37:888-893. 2010
    2010 Umbilical cord serum cytokine levels and risks of small-for-gestational-age and preterm birthAmerican Journal of Epidemiology.  171:859-867. 2010
    2010 Race of male sex partners and occurrence of bacterial vaginosisSexually Transmitted Diseases.  37:184-190. 2010
    2010 Personal hygienic behaviors and bacterial vaginosisSexually Transmitted Diseases.  37:94-99. 2010
    2010 Diagnosis and management of clinical chorioamnionitisClinics in Perinatology.  37:339-354. 2010
    2009 Vaccine prevention of maternal cytomegalovirus infectionObstetrical and Gynecological Survey.  64:502-504. 2009
    2009 Vaccine prevention of maternal cytomegalovirus infectionNew England Journal of Medicine.  360:1191-1199. 2009
    2009 Emerging concepts in antibiotic prophylaxis for cesarean delivery: A systematic reviewObstetrics and Gynecology.  113:675-682. 2009
    2009 Low intensity shear stress increases endothelial ELR+ CXC chemokine production via a focal adhesion kinase-p38β MAPK-NF-κB pathwayJournal of Biological Chemistry.  284:5945-5955. 2009
    2008 Steering Committee of the Eunice Kennedy Shriver National Institute of Child Health and Human Development's (NICHD) Maternal-Fetal Medicine Units NetworkAmerican Journal of Obstetrics and Gynecology.  199. 2008
    2008 A longitudinal study of vaginal douching and bacterial vaginosis - A marginal structural modeling analysisAmerican Journal of Epidemiology.  168:188-196. 2008
    2008 Decreasing incidence of postcesarean endometritis with extended-spectrum antibiotic prophylaxisObstetrics and Gynecology.  111:51-56. 2008
    2008 Early preterm birth: association between in utero exposure to acute inflammation and severe neurodevelopmental disability at 6 years of ageAmerican Journal of Obstetrics and Gynecology.  198:466.e1-466.e11. 2008
    2008 Genital tract methicillin-resistant Staphylococcus aureus: Risk of vertical transmission in pregnant womenObstetrics and Gynecology.  111:113-118. 2008
    2008 Impact of extended-spectrum antibiotic prophylaxis on incidence of postcesarean surgical wound infectionAmerican Journal of Obstetrics and Gynecology.  199:303.e1-303.e3. 2008
    2008 The Alabama Preterm Birth Study: Umbilical cord blood Ureaplasma urealyticum and Mycoplasma hominis cultures in very preterm newborn infantsAmerican Journal of Obstetrics and Gynecology.  198:43.e1-43.e5. 2008
    2008 Why Do Women Douche? A Longitudinal Study with Two Analytic ApproachesAnnals of Epidemiology.  18:65-73. 2008
    2007 Longitudinal association between hormonal contraceptives and bacterial vaginosis in women of reproductive ageSexually Transmitted Diseases.  34:954-959. 2007
    2007 Early second-trimester inflammatory markers and short cervical length and the risk of recurrent preterm birthJournal of Reproductive Immunology.  75:133-140. 2007
    2007 Erratum: Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population: A randomized controlled trial (Obstetrics and Gynecology (2007) 109, (392-401))Obstetrics and Gynecology.  110:936. 2007
    2007 Dietary intake of selected nutrients affects bacterial vaginosis in womenJournal of Nutrition.  137:2128-2133. 2007
    2007 The Alabama Preterm Birth Study: Diffuse decidual leukocytoclastic necrosis of the decidua basalis, a placental lesion associated with preeclampsia, indicated preterm birth and decreased fetal growthJournal of Maternal-Fetal and Neonatal Medicine.  20:391-395. 2007
    2007 Fetal fibronectin and adverse infant outcomes in a predominantly human immunodeficiency virus-infected African population: A randomized controlled trialObstetrics and Gynecology.  109:392-401. 2007
    2007 Clinical trial of interconceptional antibiotics to prevent preterm birth: subgroup analyses and possible adverse antibiotic-microbial interactionAmerican Journal of Obstetrics and Gynecology.  197:367.e1-367.e6. 2007
    2007 Impact of interconception antibiotics on the endometrial microbial floraAmerican Journal of Obstetrics and Gynecology.  196:226.e1-226.e6. 2007
    2007 ReplyAmerican Journal of Obstetrics and Gynecology.  196. 2007
    2007 The relationship between resolution of asymptomatic bacterial vaginosis and spontaneous preterm birth in fetal fibronectin-positive womenAmerican Journal of Obstetrics and Gynecology.  197:488.e1-488.e5. 2007
    2006 Association of asymptomatic bacterial vaginosis with endometrial microbial colonization and plasma cell endometritis in nonpregnant womenAmerican Journal of Obstetrics and Gynecology.  195:1611-1616. 2006
    2006 The Alabama Preterm Birth Study: Intrauterine infection and placental histologic findings in preterm births of males and females less than 32 weeksAmerican Journal of Obstetrics and Gynecology.  195:1533-1537. 2006
    2006 The International Infections in Pregnancy (IIP) study: Variations in the prevalence of bacterial vaginosis and distribution of morphotypes in vaginal smears among pregnant womenAmerican Journal of Obstetrics and Gynecology.  195:1198-1204. 2006
    2006 A pilot study of vaginal flora changes with randomization to cessation of douchingSexually Transmitted Diseases.  33:610-613. 2006
    2006 The Alabama Preterm Birth Study: Corticosteroids and neonatal outcomes in 23- to 32-week newborns with various markers of intrauterine infectionAmerican Journal of Obstetrics and Gynecology.  195:1020-1024. 2006
    2006 The Alabama Preterm Birth Project: Placental histology in recurrent spontaneous and indicated preterm birthAmerican Journal of Obstetrics and Gynecology.  195:792-796. 2006
    2006 The Alabama Preterm Birth study: polymorphonuclear and mononuclear cell placental infiltrations, other markers of inflammation, and outcomes in 23- to 32-week preterm newborn infantsAmerican Journal of Obstetrics and Gynecology.  195:803-808. 2006
    2006 Early mid-trimester serum relaxin, soluble CD163, and cervical length in women at high risk for preterm deliveryAmerican Journal of Obstetrics and Gynecology.  195:208-214. 2006
    2006 Detection of cytomegalovirus infection during a vaccine clinical trial in healthy young women: Seroconversion and viral sheddingJournal of Clinical Virology.  35:338-342. 2006
    2006 Valacyclovir therapy to reduce recurrent genital herpes in pregnant womenAmerican Journal of Obstetrics and Gynecology.  194:774-781. 2006
    2006 Midpregnancy genitourinary tract infection with Chlamydia trachomatis: Association with subsequent preterm delivery in women with bacterial vaginosis and Trichomonas vaginalisAmerican Journal of Obstetrics and Gynecology.  194:493-500. 2006
    2006 The association of psychosocial stress and bacterial vaginosis in a longitudinal cohortAmerican Journal of Obstetrics and Gynecology.  194:381-386. 2006
    2006 Interconceptional antibiotics to prevent spontaneous preterm birth: A randomized clinical trialAmerican Journal of Obstetrics and Gynecology.  194:617-623. 2006
    2005 Endometrial microbial colonization and plasma cell endometritis after spontaneous or indicated preterm versus term deliveryAmerican Journal of Obstetrics and Gynecology.  193:739-745. 2005
    2005 Spontaneous resolution of asymptomatic Chlamydia trachomatis in pregnancyObstetrics and Gynecology.  105:557-562. 2005
    2005 Use of vaginal polymorphonuclear to epithelial cell ratios for the prediction of preterm birthObstetrics and Gynecology.  105:139-144. 2005
    2005 Vulvovaginal symptoms in women with bacterial vaginosisObstetrical and Gynecological Survey.  60:26-28. 2005
    2004 Periodontal disease and upper genital tract inflammation in early spontaneous preterm birthObstetrics and Gynecology.  104:777-783. 2004
    2004 Vulvovaginal symptoms in women with bacterial vaginosisObstetrics and Gynecology.  104:267-272. 2004
    2004 Antibiotic treatment after a positive fetal fibronectin test at mid-trimester did not prevent spontaneous preterm deliveryEvidence-based Obstetrics and Gynecology.  6:64-65. 2004
    2004 The international infections in pregnancy study: Group B streptococcal colonization in pregnant womenJournal of Maternal-Fetal and Neonatal Medicine.  15:267-274. 2004
    2004 Cervicovaginal cytokines, vaginal infection, and preterm birthAmerican Journal of Obstetrics and Gynecology.  190:1179. 2004
    2003 Intrapartum chlorhexidine vaginal irrigation and chorioamnion and placental microbial colonizationJournal of the International Federation of Gynaecology and Obstetrics.  83:165-169. 2003
    2003 Clinical trial of chlorhexidine vaginal irrigation to prevent peripartal infection in nulliparous womenAmerican Journal of Obstetrics and Gynecology.  189:166-170. 2003
    2003 Randomized clinical trial of extended spectrum antibiotic prophylaxis with coverage for Ureaplasma urealyticum to reduce post-cesarean delivery endometritisObstetrics and Gynecology.  101:1183-1189. 2003
    2003 Maternal and transplacental pharmacokinetics of azithromycinAmerican Journal of Obstetrics and Gynecology.  188:714-718. 2003
    2003 Biochemical predictors of preterm labor: Fetal fibronectin and salivary estriolClinics in Perinatology.  30:701-733. 2003
    2003 Randomized clinical trial of metronidazole plus erythromycin to prevent spontaneous preterm delivery in fetal fibronectin-positive womenObstetrics and Gynecology.  101:847-855. 2003
    2003 What we have learned from an antibiotic trial in fetal fibronectin positive womenSeminars in Perinatology.  27:231-238. 2003
    2002 Elevated amniotic fluid ferritin levels are associated with inflammation-related pregnancy loss following mid-trimester amniocentesisJournal of Maternal-Fetal and Neonatal Medicine.  11:302-306. 2002
    2001 Failure of metronidazole to prevent preterm delivery among pregnant women with asymptomatic Trichomonas vaginalis infectionNew England Journal of Medicine.  345:487-493. 2001
    2001 The Preterm Prediction Study: association between cervical interleukin 6 concentration and spontaneous preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.American Journal of Obstetrics and Gynecology.  184:483-488. 2001
    2001 Midtrimester vaginal Mycoplasma genitalium in women with subsequent spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  185:163-165. 2001
    2001 The preterm prediction study: Association between cervical interleukin 6 concentration and spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  184:483-488. 2001
    2001 Vaginal fetal fibronectin levels and spontaneous preterm birth in symptomatic womenObstetrics and Gynecology.  97:225-228. 2001
    2000 Infection and preterm birthAmerican Journal of Perinatology.  17:357-365. 2000
    2000 Surveillance of behavioral risk factors and infections using prenatal clinic data: A comparison with other data sourcesPrenatal and Neonatal Medicine.  5:368-374. 2000
    2000 Intrauterine infection and preterm deliveryNew England Journal of Medicine.  342:1500-1507. 2000
    2000 The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.American Journal of Obstetrics and Gynecology.  182:631-635. 2000
    2000 The preterm prediction study: granulocyte colony-stimulating factor and spontaneous preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.American Journal of Obstetrics and Gynecology.  182:625-630. 2000
    2000 Second-trimester cervical ultrasound: Associations with increased risk for recurrent early spontaneous deliveryObstetrics and Gynecology.  95:222-226. 2000
    2000 Erratum: Mid-trimester vaginal biological markers of infection predictive of lower genital tract fetal fibronectin (FFN) (American Journal of Obstetrics and Gynecology (2000) 182 (1-2))American Journal of Obstetrics and Gynecology.  182:751. 2000
    2000 Puerperal infection after cesarean delivery: Evaluation of a standardized protocolAmerican Journal of Obstetrics and Gynecology.  182:1147-1151. 2000
    2000 The Preterm Prediction Study: Cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birthAmerican Journal of Obstetrics and Gynecology.  182:631-635. 2000
    2000 The Preterm Prediction Study: Granulocyte colony-stimulating factor and spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  182:625-630. 2000
    2000 The preterm prediction study: Association of second-trimester genitourinary chlamydia infection with subsequent spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  183:662-668. 2000
    1999 Syphilis, gonorrhoea, and drug abuse among pregnant women in Jefferson County, Alabama, US, 1980-94: Monitoring trends through systematically collected health services dataSexually Transmitted Infections.  75:300-305. 1999
    1999 The Preterm Prediction Study: Failure of midtrimester cervical sialidase level elevation to predict subsequent spontaneous preterm birthAmerican Journal of Obstetrics and Gynecology.  180:1151-1154. 1999
    1999 The association of interleukin 6 with clinical and laboratory parameters of acute pelvic inflammatory diseaseAmerican Journal of Obstetrics and Gynecology.  181:940-944. 1999
    1998 Choriodecidual inflammation: A potentially preventable cause of perinatal HIV-1 transmission?Lancet.  352:1927-1930. 1998
    1998 Antibiotic susceptibility profile of group B streptococcus acquired verticallyObstetrics and Gynecology.  92:931-934. 1998
    1998 Infection-related risk factors predictive of spontaneous preterm labor and birthPrenatal and Neonatal Medicine.  3:86-90. 1998
    1998 Markers of preterm birthPrenatal and Neonatal Medicine.  3:43-46. 1998
    1998 Intrauterine viral infection at the time of second trimester genetic amniocentesisObstetrics and Gynecology.  92:420-424. 1998
    1998 Bacterial vaginosis: Association with adverse pregnancy outcomeSeminars in Perinatology.  22:242-250. 1998
    1998 Elevated second-trimester amniotic fluid interleukin-6 levels predict preterm deliveryAmerican Journal of Obstetrics and Gynecology.  178:546-550. 1998
    1998 Pharmacokinetics of oral valacyclovir and acyclovir in late pregnancyAmerican Journal of Obstetrics and Gynecology.  179:846-851. 1998
    1998 Use of antibiotics to prevent preterm birth [2] (multiple letters)American Journal of Obstetrics and Gynecology.  178:624-625. 1998
    1997 Improved HIV-1 group M seroconversion and HIV-1 group O sensitivity of the new ortho HIV-1/HIV-2 Ab-capture ELISA test systemInfusion Therapy and Transfusion Medicine.  24:190. 1997
    1997 Mid-trimester interleukin-6 levels in twin pregnanciesActa diabetologica latina.  176. 1997
    1997 The preterm prediction study: association between cervical interleukin-6 (il-6), fetal fibronectin (ffn), and spontaneous preterm birth (sptb)Acta diabetologica latina.  176. 1997
    1997 The preterm prediction study: association of mid-trimester genital chlamydia infection and subsequent spontaneous preterm birth (SPTB)Acta diabetologica latina.  176. 1997
    1997 Genital herpes during pregnancy: Inability to distinguish primary and recurrent infections clinicallyObstetrics and Gynecology.  89:891-895. 1997
    1997 Sexually transmitted diseases and adverse outcomes of pregnancyClinics in Perinatology.  24:23-41. 1997
    1997 Detection of genitourinary tract Chlamydia trachomatis infection in pregnant women by ligase chain reaction assayObstetrics and Gynecology.  89:556-560. 1997
    1997 Chlorhexidine vaginal irrigation for the prevention of peripartal infection: A placebo-controlled randomized clinical trialAmerican Journal of Obstetrics and Gynecology.  176:617-622. 1997
    1997 Fetal fibronectin as a predictor of preterm birth in patients with symptoms: A multicenter trialAmerican Journal of Obstetrics and Gynecology.  177:13-18. 1997
    1997 Measurement of amniotic fluid interleukin-6 using commercial kits.Infectious Diseases in Obstetrics & Gynecology.  5:222-225. 1997
    1997 Necrotizing fasciitis after cesarean deliveryObstetrical and Gynecological Survey.  89:409-412. 1997
    1996 Bacterial colonization of the vagina during pregnancy in four ethnic groupsAmerican Journal of Obstetrics and Gynecology.  174:1618-1621. 1996
    1996 Dynamics of the fetal adrenal, cholesterol, and apolipoprotein B responses to antenatal betamethasone therapyAmerican Journal of Obstetrics and Gynecology.  174:562-565. 1996
    1996 Elevated amniotic fluid interleukin-6 levels at genetic amniocentesis predict subsequent pregnancy lossAmerican Journal of Obstetrics and Gynecology.  175:830-833. 1996
    1996 Intrauterine infection and why preterm prevention programs have failed.American Journal of Public Health.  86:781-783. 1996
    1995 Reduced incidence of preterm delivery with metronidazole and erythromycin in women with bacterial vaginosisNew England Journal of Medicine.  333:1732-1736. 1995
    1995 Preterm labor: Emerging role of genital tract infectionsInfectious agents and disease.  4:196-211. 1995
    1995 Amnioinfusion survey: prevalence, protocols, and complications.Obstetrics and Gynecology.  86:572-576. 1995
    1995 Diagnosis of Chlamydia trachomatis genitourinary infection in women by ligase chain reaction assay of urineLancet.  345:213-216. 1995
    1995 Amnioinfusion survey: prevalence, protocols, and complicationsObstetrics and Gynecology.  86:572-576. 1995
    1995 Amniotic fluid interleukin-6: Correlation with upper genital tract microbial colonization and gestational age in women delivered after spontaneous labor versus indicated deliveryAmerican Journal of Obstetrics and Gynecology.  173:606-612. 1995
    1995 Association of post-cesarean delivery endometritis with colonization of the chorioamnion by Ureaplasma urealyticumObstetrics and Gynecology.  85:509-514. 1995
    1995 Risk factors for the development of preterm premature rupture of the membranes after arrest of preterm laborAmerican Journal of Obstetrics and Gynecology.  173:1310-1315. 1995
    1995 Screening and treatment of asymptomatic bacteriuria of pregnancy to prevent pyelonephritisObstetrics and Gynecology.  86:868. 1995
    1995 Screening and treatment of asymptomatic bacteriuria of pregnancy to prevent pyelonephritis: A cost-effectiveness and cost-benefit analysisObstetrics and Gynecology.  86:119-123. 1995
    1995 The preterm prediction study: Significance of vaginal infectionsAmerican Journal of Obstetrics and Gynecology.  173:1231-1235. 1995
    1994 Bed rest in pregnancyObstetrics and Gynecology.  84:131-136. 1994
    1994 Effect of magnesium sulfate on eicosanoid levels in women with pregnancy-induced hypertensionClinical and experimental hypertension. Part B, Hypertension in pregnancy.  13:71-82. 1994
    1994 Ligase chain reaction to detect Chlamydia trachomatis infection of the cervixJournal of Clinical Microbiology.  32:2540-2543. 1994
    1994 Wound complications after cesarean sectionsClinical Obstetrics and Gynecology.  37:842-855. 1994
    1992 Effect of Type of Anesthesia on Blood Loss at Elective Repeat Cesarean SectionAmerican Journal of Perinatology.  9:197-200. 1992
    1992 Expectant management of preterm ruptured membranes: Effects of antimicrobial therapyObstetrics and Gynecology.  80:759-762. 1992
    1992 Maternal and perinatal effects of hypertension at termJournal of Reproductive Medicine.  37:73-76. 1992
    1992 New-generation RIBA hepatitis C strip immunoblot assays.Beitrage zur Infusionstherapie = Contributions to infusion therapy.  30:17-33. 1992
    1991 Elective hospitalization in the management of twin pregnanciesObstetrics and Gynecology.  77:826-831. 1991
    1990 Urinary tract infections in pregnancyInternational Urogynecology Journal.  1:155-163. 1990
    1987 A role for aromatizable androgens in female rat pubertyBiology of Reproduction.  36:836-843. 1987
    1982 Studies on the central effect of prolactin in inducing precocious puberty in the female ratBrain Research Bulletin.  8:449-458. 1982
    1981 Current studies on the mechanisms underlying the onset of female puberty.Progress in clinical and biological research.  74:199-218. 1981
    1981 A detailed analysis of the serum luteinizing hormone secretory profile in conscious, free-moving female rats during the time of pubertyEndocrinology.  109:2032-2039. 1981
    1981 A quantitative analysis of the maturation of steroid negative feedbacks controlling gonadotropin release in the female rat: The infantile-juvenile periods, transition from an androgenic to a predominantly estrogenic controlEndocrinology.  108:1313-1320. 1981
    1981 Development of estradiol-positive feedback on luteinizing hormone release in the female rat: A quantitative studyEndocrinology.  109:1404-1413. 1981
    1981 The infantile female rat: In vivo ovarian and adrenal steroidogenic responses to exogenous administration or to endogenously induced elevations of gonadotropins and ACTHBiology of Reproduction.  24:597-608. 1981
    1980 Neuroendocrine control of the onset of puberty in the ratFederation proceedings.  39:2365-2371. 1980
    1980 Recent advances in the endocrinology of pubertyRecent Progress in Hormone Research.  1:228-257. 1980
    1980 The First Proestrus in the Female Rat: Circulating Steroid Levels Preceding and Accompanying the Preovulatory LH SurgeProceedings of the Society for Experimental Biology and Medicine.  163:305-309. 1980
    1979 Changes in ovarian steroidal and prostaglandin e responsiveness to gonadotropins during the onset of puberty in the female ratEndocrinology.  104:653-658. 1979
    1979 Progesterone (P) restores prepubertal effectiveness of estrogen negative feedback on gonadotropin release in adult female ratsFederation proceedings.  38. 1979
    1978 Control of luteinizing hormone release in prepubertal female rats: Evidence for an enhanced ability of the hypothalamus to release luteinizing hormone releasing hormone as the pituitary responsiveness to luteinizing hormone releasing hormone declinesJournal of Endocrinology.  78:281-282. 1978
    1978 Ovarian and adrenal secretion of sex steroids in infantile rats: stimulation by gonadotropins and ACTHFederation proceedings.  37. 1978
    1977 On the feedback actions of estrogen on gonadotropin and prolactin release in infantile female ratsEndocrinology.  101:1517-1523. 1977

    Research Overview

  • Dr. Andrews is a Professor in the UAB Maternal-Fetal Medicine Division, and has been the Director of the Obstetrics and Gynecology Infectious Disease Research Laboratory since its creation in 1990. Dr. Andrews' research interests relate to obstetrical infections and infection-related preterm birth. He is the PI for an investigation of Interconceptional Antibiotics to Prevent Recurrent Preterm Birth (HD33883 09/20/96-08/31/01; $767,150) that was recently completed and is the protocol chairman of a prospective randomized trial within the NICHD MFM Units Network of antibiotics to prevent preterm birth in women with elevated mid-trimester cervical fibronectin that is in the analysis phase. The projected budget for this investigation is approximately $2,000,000. He is also the PI of Project IV within the UAB Rural Perinatal Emphasis Research Center (1 P01 HD33927-01; 04/05/96-3/31/01; $455,397) which is an evaluation of a neonatal sepsis-like syndrome related to in utero maternal cytokine exposure. Most recently he was awarded a contract to perform "A Longitudinal Study of Bacterial Vaginosis" (NICHD-NO-HD-8-3293; 05/01/98-04/30/02; $2,943,932). Dr. Andrews is a consultant and co-investigator on numerous other interdisciplinary projects related to genital tract infections, sexually transmitted diseases, and preterm birth, and he is a co-investigator within the International Clinical Epidemiology Network (INCLEN). Dr. Andrews is a committed experienced investigator who has been recognized by his department and by the Counsel on Resident Education in Obstetrics and Gynecology for his contribution to education and training. He will continue to be an excellent mentor for fellows and young faculty within the Department of Obstetrics and Gynecology and the CRWH. Previous Maternal-Fetal Medicine trainees include: Drs. Alice Goepfert (UAB), Francisco Gaudier, Debora Kimberlin (Brookwood Hospital), Dwight Rouse (UAB), Wendy Atkinson, Patrick Ramsey (UAB), and George Lu.
  • Principal Investigator On

  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2018 - 2019
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2018 - 2019
  • Sub-Grantee Agreement Between ADPH And The UAB Department Of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2017 - 2018
  • OB/GYN Faculty Research Career Development Program  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2018
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2016 - 2017
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2015 - 2016
  • Redefining Dystocia Diagnosis in Labor using Electrohysterography (RIDDLE)  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2015 - 2016
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2014 - 2015
  • OB/GYN Faculty Research Career Development Program  awarded by National Institute of Child Health and Human Development/NIH/DHHS 2010 - 2015
  • APGO International Scholarship for OB-Gyn Educators Award  awarded by Association of Professors of Gynecology & Obstetrics Medical Education Fndn. 2015
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2013 - 2014
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB/GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2012 - 2013
  • Implementation of Programs to Improve the Prevention of Mother to Child Transmission; the Care and Treatment of HIV and AIDS in Eastern, Lusaka, Southern and Western Provinces of the Republic of Zambia Under the President's Emergency Plan for AIDS Relief (PEPFAR)  awarded by Centre for Infectious Disease Research in Zambia (CIDRZ) 2011 - 2012
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB-GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2011 - 2012
  • Sub-Grantee Agreement Between ADPH and the UAB Department of OB-GYN, Birmingham, AL  awarded by ALABAMA DEPARTMENT OF PUBLIC HEALTH 2010 - 2012
  • Private Grant  awarded by BOSTON SCIENTIFIC CORPORATION 2011 - 2012
  • Private Grant  awarded by Ethicon Endo-Surgery 2011
  • Education And Training

  • UAB Hospital, Internship 1985
  • UAB Hospital, Residency 1988
  • University of Texas Southwestern Medical Center, Postdoctoral Fellowship 1990
  • Full Name

  • William Andrews