| Year |
Title |
Altmetric |
| 2022
|
Monitoring SARS-CoV-2 Infection Using a Double Reporter-Expressing Virus.
Microbiology Spectrum.
10.
2022
|
|
| 2022
|
Potent universal beta-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody.
PLoS Pathogens.
18.
2022
|
|
| 2022
|
Immunization with recombinant accessory protein-deficient SARS-CoV-2 protects against lethal challenge and viral transmission.
2022
|
|
| 2022
|
Potent universal-coronavirus therapeutic activity mediated by direct respiratory administration of a Spike S2 domain-specific human neutralizing monoclonal antibody.
2022
|
|
| 2022
|
Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane.
Cell Reports: Methods.
2.
2022
|
|
| 2021
|
A bifluorescent-based assay for the identification of neutralizing antibodies against SARS-CoV-2 variants of concern in vitro and in vivo.
Journal of Virology.
95.
2021
|
|
| 2021
|
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses
2021
|
|
| 2021
|
Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern.
Frontiers in Immunology.
12.
2021
|
|
| 2021
|
Generation and characterization of recombinant SARS-CoV-2 expressing reporter genes.
Journal of Virology.
95.
2021
|
|
| 2021
|
Selection, identification, and characterization of SARS-CoV-2 monoclonal antibody resistant mutants.
Journal of Virological Methods.
290.
2021
|
|
| 2021
|
Therapeutic activity of an inhaled potent SARS-CoV-2 neutralizing human monoclonal antibody in hamsters.
Cell Reports Medicine.
2.
2021
|
|
| 2021
|
Editorial: Structures, Signaling Mechanisms, and Functions of Types I and III Interferons.
Frontiers in Immunology.
12.
2021
|
|
| 2021
|
Rapid in vitro assays for screening neutralizing antibodies and antivirals against SARS-CoV-2.
Journal of Virological Methods.
287.
2021
|
|
| 2020
|
The Role of Structure in the Biology of Interferon Signaling.
Frontiers in Immunology.
11.
2020
|
|
| 2020
|
Engineered il-10 variants elicit potent immunomodulatory effects at low ligand doses.
Science Signaling.
13.
2020
|
|
| 2020
|
Characterization of Type-I IFN subtype autoantibodies and activity in SLE serum and urine.
Lupus.
29:1095-1105.
2020
|
|
| 2020
|
Cytomegalovirus-vectored vaccines for HIV and other pathogens.
AIDS.
34:335-349.
2020
|
|
| 2019
|
Analysis of interleukin-20 receptor complexes in trabecular meshwork cells and effects of cytokine signaling in anterior segment perfusion culture.
Molecular Vision.
25:266-282.
2019
|
|
| 2019
|
Neutralization of rhesus cytomegalovirus IL-10 reduces horizontal transmission and alters long-term immunity
2019
|
|
| 2018
|
Human interferon- and interferon- exhibit low potency and low affinity for cell-surface IFNAR and the poxvirus antagonist B18R.
Journal of Biological Chemistry.
293:16057-16068.
2018
|
|
| 2017
|
Cutting Edge: Endogenous IFN-β regulates survival and development of transitional B cells.
Journal of Immunology.
199:2618-2623.
2017
|
|
| 2017
|
A panel of synthetic antibodies that selectively recognize and antagonize members of the interferon alpha family
2017
|
|
| 2017
|
Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys.
JCI Insight.
2.
2017
|
|
| 2017
|
Plasmablast response to primary rhesus cytomegalovirus (CMV) infection in a monkey model of congenital CMV transmission.
Clinical and Vaccine Immunology.
24.
2017
|
|
| 2016
|
Missense splice variant (g.20746A>G, p.Ile183Val) of interferon gamma receptor 1 (IFNGR1) coincidental with mycobacterial osteomyelitis - a screen of osteoarticular lesions
2016
|
|
| 2016
|
Missense splice variant (g.20746A>G, p.Ile183Val) of interferon gamma receptor 1 (IFNGR1) coincidental with mycobacterial osteomyelitis - a screen of osteoarticular lesions.
2016
|
|
| 2016
|
VpreB serves as an invariant surrogate antigen for selecting immunoglobulin antigen-binding sites..
Science Immunology.
1:aaf6628.
2016
|
|
| 2016
|
The susceptibility of primary cultured rhesus macaque kidney epithelial cells to rhesus cytomegalovirus strains.
Journal of General Virology.
97:1426-1438.
2016
|
|
| 2016
|
A heterozygous RAB27A mutation associated with delayed cytolytic granule polarization and hemophagocytic lymphohistiocytosis.
Journal of Immunology.
196:2492-2503.
2016
|
|
| 2016
|
Cytokine activation by antibody fragments targeted to cytokine-receptor signaling complexes.
Journal of Biological Chemistry.
291:447-461.
2016
|
|
| 2016
|
Exploitation of interleukin-10 (IL-10) signaling pathways: Alternate roles of viral and cellular IL-10 in rhesus cytomegalovirus infection.
Journal of Virology.
90:9920-9930.
2016
|
|
| 2016
|
VpreB serves as an invariant surrogate antigen for selecting immunoglobulin antigen-binding sites.
Science Immunology.
1.
2016
|
|
| 2015
|
Elucidating new drug targets in psoriasis by gene profiling: An opportunity to be seized.
Annals of translational medicine.
3.
2015
|
|
| 2014
|
Production and characterization of thirteen human type-I interferon-α subtypes.
Protein Expression and Purification.
103:75-83.
2014
|
|
| 2014
|
The molecular basis of IL-10 function: From receptor structure to the onset of signaling.
Current Topics in Microbiology and Immunology.
380:191-212.
2014
|
|
| 2014
|
The old but new IgM Fc receptor (Fc;R).
Current Topics in Microbiology and Immunology.
382:3-28.
2014
|
|
| 2014
|
Very early onset inflammatory bowel disease associated with aberrant trafficking of IL-10R1 and cure by T cell replete haploidentical bone marrow transplantation.
Journal of Clinical Immunology.
34:331-339.
2014
|
|
| 2013
|
Vaccination against a virus-encoded cytokine significantly restricts viral challenge.
Journal of Virology.
87:11323-11331.
2013
|
|
| 2013
|
Kinetic analysis of cytokine-mediated receptor assembly using engineered FC heterodimers.
Protein Science.
22:1100-1108.
2013
|
|
| 2012
|
Epstein-barr virus IL-10 engages IL-10R1 by a two-step mechanism leading to altered signaling properties.
Journal of Biological Chemistry.
287:26586-26595.
2012
|
|
| 2012
|
Structural basis for receptor sharing and activation by interleukin-20 receptor-2 (IL-20R2) binding cytokines
2012
|
|
| 2012
|
Host immune responses to a viral immune modulating protein: Immunogenicity of viral interleukin-10 in Rhesus cytomegalovirus-infected rhesus macaques.
PLoS One.
7.
2012
|
|
| 2012
|
Purification, crystallization and preliminary X-ray diffraction analysis of the IL-20-IL-20R1-IL-20R2 complex.
Acta Crystallographica Section F: Structural Biology Communications.
68:89-92.
2012
|
|
| 2011
|
Design and analysis of rhesus cytomegalovirus IL-10 mutants as a model for novel vaccines against human cytomegalovirus.
PLoS One.
6.
2011
|
|
| 2010
|
Interleukin-26: An IL-10-related cytokine produced by Th17 cells.
Cytokine and Growth Factor Reviews.
21:393-401.
2010
|
|
| 2010
|
Substitution of adenovirus serotype 3 hexon onto a serotype 5 oncolytic adenovirus reduces factor X binding, decreases liver tropism, and improves antitumor efficacy.
Molecular Cancer Therapeutics.
9:2536-2544.
2010
|
|
| 2010
|
Cytokine-receptor interactions as drug targets.
Current Opinion in Chemical Biology.
14:511-519.
2010
|
|
| 2010
|
Structure and mechanism of receptor sharing by the IL-10R2 common chain.
Folding & design.
18:638-648.
2010
|
|
| 2010
|
A docking model based on mass spectrometric and biochemical data describes phage packaging motor incorporation.
Molecular and Cellular Proteomics.
9:1764-1773.
2010
|
|
| 2008
|
Structure of IL-22 Bound to Its High-Affinity IL-22R1 Chain.
Folding & design.
16:1333-1344.
2008
|
|
| 2008
|
Crystallization and preliminary X-ray diffraction analysis of human IL-22 bound to the extracellular IL-22R1 chain.
Acta Crystallographica Section F: Structural Biology Communications.
64:266-269.
2008
|
|
| 2008
|
Structure and mechanism of IFN-γ antagonism by an orthopoxvirus IFN-γ-binding protein
2008
|
|
| 2007
|
Isolation of flagellated bacteria implicated in Crohn's disease.
Inflammatory Bowel Diseases.
13:1191-1201.
2007
|
|
| 2007
|
Identification and characterization of a +1 frameshift observed during the expression of Epstein-Barr virus IL-10 in Escherichia coli.
Protein Expression and Purification.
53:132-137.
2007
|
|
| 2007
|
Protein crystallization..
Methods in Molecular Biology.
383:337-349.
2007
|
|
| 2006
|
Conformational changes mediate interleukin-10 receptor 2 (IL-10R2) binding to IL-10 and assembly of the signaling complex.
Journal of Biological Chemistry.
281:35088-35096.
2006
|
|
| 2006
|
The unique C termini of orthopoxvirus gamma interferon binding proteins are essential for ligand binding.
Journal of Virology.
80:10675-10682.
2006
|
|
| 2006
|
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
Cancer Research.
66:8182-8191.
2006
|
|
| 2006
|
Characterization of monocyte-derived dendritic cells maturated with IFN-α.
Scandinavian Journal of Immunology.
63:217-222.
2006
|
|
| 2005
|
Unique aspects of mda-7/IL-24 antitumor bystander activity: Establishing a role for secretion of MDA-7/IL-24 protein by normal cells.
Oncogene.
24:7552-7566.
2005
|
|
| 2005
|
Structure of insect-cell-derived IL-22.
Acta crystallographica. Section D, Structural biology.
61:942-950.
2005
|
|
| 2005
|
Phenotypic and functional characterization of clinical grade dendritic cells generated from patients with advanced breast cancer for therapeutic vaccination.
Scandinavian Journal of Immunology.
61:147-156.
2005
|
|
| 2005
|
Same structure, different function: Crystal structure of the Epstein-Barr virus IL-10 bound to the soluble IL-10r1 chain.
Folding & design.
13:551-564.
2005
|
|
| 2004
|
Interferons, interferon-like cytokines, and their receptors.
Immunological Reviews.
202:8-32.
2004
|
|
| 2004
|
The IL-10R2 binding hot spot on IL-22 is located on the N-terminal helix and is dependent on N-linked glycosylation.
Journal of Molecular Biology.
342:503-514.
2004
|
|
| 2004
|
Crystallization and X-ray diffraction analysis of insect-cell-derived IL-22.
Acta crystallographica. Section D, Structural biology.
60:1295-1298.
2004
|
|
| 2004
|
Interleukin-10 and related cytokines and receptors.
Annual Review of Immunology.
22:929-979.
2004
|
|
| 2004
|
An Early Stage of Mason-Pfizer Monkey Virus Budding Is Regulated by the Hydrophobicity of the Gag Matrix Domain Core.
Journal of Virology.
78:5023-5031.
2004
|
|
| 2004
|
Induction of regulatory dendritic cells by dexamethasone and 1α,25-Dihydroxyvitamin D3.
Immunology Letters.
91:63-69.
2004
|
|
| 2004
|
Crystallization of cytokine-receptor complexes..
Methods in Molecular Biology.
249:81-92.
2004
|
|
| 2004
|
Structural analysis of IL-10 and type I interferon family members and their complexes with receptor.
Advances in protein chemistry and structural biology.
68:171-223.
2004
|
|
| 2002
|
Type I interferon structures: Possible scaffolds for the interferon-alpha receptor complex.
Canadian Journal of Chemistry.
80:1166-1173.
2002
|
|
| 2002
|
Structure of interleukin-10/interleukin-10R1 complex: A paradigm for class 2 cytokine activation.
Immunologic Research.
26:303-308.
2002
|
|
| 2002
|
Crystal structures of α-helical cytokine-receptor complexes: We've only scratched the surface
2002
|
|
| 2002
|
Noncompetitive antibody neutralization of IL-10 revealed by protein engineering and X-ray crystallography.
Folding & design.
10:981-987.
2002
|
|
| 2002
|
Crystal structure of human cytomegalovirus IL-10 bound to soluble human IL-10R1
2002
|
|
| 2002
|
Comparison of interleukin-22 and interleukin-10 soluble receptor complexes.
Journal of Interferon and Cytokine Research.
22:1099-1112.
2002
|
|
| 2001
|
Purification, crystallization and preliminary X-ray diffraction of a complex between IL-10 and soluble IL-10R1.
Acta Crystallographica Section D: Biological Crystallography.
57:1908-1911.
2001
|
|
| 2001
|
Purification, crystallization and preliminary X-ray diffraction of a complex between IL-10 and soluble IL-10R1..
Acta crystallographica. Section D, Structural biology.
57:1908-1911.
2001
|
|
| 2001
|
Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.
Immunity.
15:35-46.
2001
|
|
| 2000
|
The COOH-terminal nuclear localization sequence of interferon γ regulates STAT1α nuclear translocation at an intracellular site.
Journal of Cell Science.
113:2771-2781.
2000
|
|
| 2000
|
Erratum: Design and analysis of an engineered human interleukin-10 monomer (Journal of Biological Chemistry (2000) 275 (13552-13557)).
Journal of Biological Chemistry.
275:25054.
2000
|
|
| 2000
|
Design, characterization, and structure of a biologically active single-chain mutant of human IFN-γ.
Journal of Molecular Biology.
299:169-179.
2000
|
|
| 2000
|
Design and analysis of an engineered human interleukin-10 monomer.
Journal of Biological Chemistry.
275:13552-13557.
2000
|
|
| 1999
|
Crystal structure of ovine interferon-τ at 2.1 Å resolution.
Journal of Molecular Biology.
286:151-162.
1999
|
|
| 1998
|
Structural and theoretical studies suggest domain movement produces an active conformation of thymidine phosphorylase.
Journal of Molecular Biology.
281:285-299.
1998
|
|
| 1998
|
Review of recent developments in the molecular characterization of recombinant alfa interferons on the 40th anniversary of the discovery of interferon.
Cancer Biotherapy and Radiopharmaceuticals.
13:143-154.
1998
|
|
| 1997
|
Three-dimensional models of interferon-alpha subtypes IFN-con1, IFN-alpha8, andIFN-alpha1 derived from the crystal structure of IFN-alpha2b..
Seminars in Oncology.
24.
1997
|
|
| 1997
|
Structural biology of cytokines, their receptors, and signaling complexes: Implications for the immune and neuroendocrine circuit.
Chemical immunology and allergy.
69:76-98.
1997
|
|
| 1997
|
Three-dimensional models of interferon-α subtypes IFN-con1, IFN-α8, and IFN-α1 derived from the crystal structure of IFN-α(2b).
Seminars in Oncology.
24.
1997
|
|
| 1996
|
Zinc mediated dimer of human interferon-α(2b) revealed by X-ray crystallography.
Folding & design.
4:1453-1463.
1996
|
|
| 1995
|
Crystal structure of a complex between interferon-γ and its soluble high-affinity receptor.
Nature.
376:230-235.
1995
|
|
| 1995
|
Crystal Structure of Interleukin 10 Reveals an Interferon γ-like Fold.
Biochemistry.
34:12118-12125.
1995
|
|
| 1995
|
Crystallization and preliminary X‐ray investigation of recombinant human interleukin 10
1995
|
|
| 1994
|
Drug Binding by Calmodulin: Crystal Structure of a Calmodulin-Trifluoperazine Complex.
Biochemistry.
33:15259-15265.
1994
|
|
| 1994
|
Comparison of four independently determined structures of human recombinant interleukin-4.
Nature Structural and Molecular Biology.
1:301-310.
1994
|
|
| 1992
|
Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.
Journal of Molecular Biology.
224:1075-1085.
1992
|
|
| 1992
|
Crystal structure of recombinant human interleukin-4.
Journal of Biological Chemistry.
267:20371-20376.
1992
|
|
| 1990
|
Three-dimensional structure of thymidine phosphorylase from Escherichia coli at 2.8 Å resolution.
Journal of Biological Chemistry.
265:14016-14022.
1990
|
|
