Positions

Overview

  • I am a hematopathologist with four decades of clinical and diagnostic expertise in Flow Cytometry, benign and neoplastic hematopathology, lymphoma, leukemia, myelodysplastic/myeloproliferative neoplasms, plasma cell neoplasms/myeloma, hemoglobinopathies and Surgical Pathology. As educator, I developed Hematopathology teaching guidelines and curriculum for UAB Hematopathology fellows/trainees, and collaborated with other national experts in publishing training guidelines for Hematopathology programs. I have similarly developed curriculum and teaching material for the UAB School of Medicine (UASOM) MS-II students. Additionally, I am the section Head of UAB Health system Hematology/Bone marrow laboratories, providing overall direction and responsible for QA/QC of the above laboratories.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 In Reply: 2019
    2019 Three neglected numbers in the CBC: The RDW, MPV, and NRBC count 2019
    2019 Optimization of Laboratory Ordering Practices for Complete Blood Count with Differential 2019
    2019 Fat embolism syndrome due to bone marrow necrosis in patients with hemoglobinopathies: A life-threatening complication mimicking thrombotic thrombocytopenic purpura 2019
    2018 Primary Bone Marrow Diffuse Large B-cell Lymphoma Presenting as Transverse Myelitis 2018
    2018 Trends in bone marrow sampling and core biopsy specimen adequacy in the United States and Canada: A multicenter study 2018
    2018 Peripheral T-cell lymphoma, not otherwise specified, presenting with generalized ulcerated plaques and hypereosinophilia 2018
    2017 A fatal case of systemic lupus erythematosus complicated by macrophage activation syndrome, portal vein thrombosis and acute colitis 2017
    2017 Myeloproliferative neoplasms, version 2.2018 featured Updates to the NCCN guidelines 2017
    2017 The assembly competence domain is essential for inv(16)-associated acute myeloid leukemia 2017
    2017 An Unusual Presentation of Thrombotic Thrombocytopenic Purpura 2017
    2017 Pilot phase II study of metronomic chemotherapy in combination with bevacizumab in patients with advanced non-squamous non-small cell lung cancer 2017
    2017 ALK-positive large b-cell lymphoma 2017
    2016 NCCN Guidelines Insights: Chronic Myeloid Leukemia, Version 1.2017. 2016
    2016 NCCN guidelines® insights: Chronic myeloid leukemia, version 1.2017: Featured updates to the NCCN guidelines 2016
    2016 Oct2 and Bob1 are sensitive and specific markers in lineage determination of B cell lymphomas with no expression of conventional B cell markers 2016
    2016 B-cell lymphoma of the pericardium presenting with ventricular tachycardia with a successful catheter ablation 2016
    2016 Fat embolism syndrome secondary to bone marrow necrosis in patients with hemoglobinopathies 2016
    2016 Is low positive JAK2 V617F mutation test result clinically significant?: Multi-institutional study 2016
    2016 Treatment of CD30-positive systemic mastocytosis with brentuximab vedotin 2016
    2014 Chronic myelogenous leukemia, version 1.2015 2014
    2014 Clinicopathological and molecular features of myeloid sarcoma as initial presentation of therapy-related myeloid neoplasms: a single institution experience 2014
    2014 Out with the bad and in with the good; Red cell exchange, white cell reduction, and platelet reduction 2014
    2014 Trisomy 21-associated transient abnormal myelopoiesis involving the maternal space of the placenta: A case report and literature review 2014
    2013 Chronic Myelogenous Leukemia, Version 1.2014. 2013
    2013 Chronic myelogenous leukemia, version 1.2014: Featured updates to the NCCN guidelines 2013
    2013 Acquired von Willebrand's disease in myelofibrosis and essential thrombocythemia 2013
    2013 Cardiac device-related invasive aspergilloma assessed by live/real time three-dimensional transthoracic echocardiography 2013
    2013 The price of drugs for chronic myeloid leukemia (CML) is a reflection of the unsustainable prices of cancer drugs: From the perspective of a large group of CML experts 2013
    2013 Examining racial differences in diffuse large B-cell lymphoma presentation and survival 2013
    2012 Endoscopic ultrasound and endobronchial ultrasound-guided fine-needle aspiration of deep-seated lymphadenopathy: Analysis of 1338 cases 2012
    2012 Extracavitary KSHV-associated large B-cell lymphoma: A distinct entity or a subtype of primary effusion lymphoma? study of 9 cases and review of an additional 43 cases 2012
    2012 Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement 2012
    2012 Multiorgan failure and bone marrow necrosis in three adults with sickle cell-β +-thalassemia 2012
    2012 CD138 (syndecan-1) expression in bone-forming tumors 2012
    2012 Distinct classes of c-Kit-activating mutations differ in their ability to promote RUNX1-ETO-associated acute myeloid leukemia 2012
    2012 Chronic myelogenous leukemia 2012
    2012 Leukaemia cutis 2012
    2011 Phase II study of dose-intense chemotherapy with sequential topoisomerase-targeting regimens with irinotecan/oxaliplatin followed by etoposide/carboplatin in chemotherapy naive patients with extensive small cell lung cancer 2011
    2011 Erratum: Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples (Journal of Biomedical Optics (2010) 15 (067005)) 2011
    2011 Extramedullary hematopoiesis: an unusual finding in subdural hematomas. 2011
    2010 Development of combination tapered fiber-optic biosensor dip probe for quantitative estimation of interleukin-6 in serum samples 2010
    2010 Systemic neutrophilic aggregates in transfusion-related acute lung injury 2010
    2010 Intranasal eosinophilic angiocentric fibrosis: A case report and review 2010
    2010 Quantitative estimation of IL-6 in serum/plasma samples using a rapid and cost-effective fiber optic dip-probe 2010
    2009 Solitary plaque on the scalp as a primary manifestation of Hodgkin lymphoma: A case report and review of the literature 2009
    2009 Primary cutaneous peripheral t-cell lymphoma with aberrant coexpression of CD20: Case report and review of the literature 2009
    2009 Prevalence of elevated hemoglobin A 2 measured by the CAPILLARYS system 2009
    2008 Myelofibrosis in a patient with familial hemophagocytic lymphohistiocytosis 2008
    2008 FLT3-ITD cooperates with inv(16) to promote progression to acute myeloid leukemia 2008
    2008 Transfusion-related acute lung injury: Past, present, and future 2008
    2008 Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of beast cancer bone metastasis 2008
    2007 Idiopathic eosinophilia associated CMML-2 with overexpression of the ETV6 gene 2007
    2007 Successful treatment of T-cell prolymphocytic leukemia with full-intensity conditioning followed by matched unrelated donor allogeneic stem cell transplantation 2007
    2007 Reciprocal co-expression of Fas and Fas ligand in human cholangiocarcinoma 2007
    2007 Dominant inhibition of Fas ligand-mediated apoptosis due to a heterozygous mutation associated with autoimmune lymphoproliferative syndrome (ALPS) Type Ib 2007
    2007 Recommended curriculum for teaching hematopathology to subspecialty hematopathology fellows 2007
    2006 Non-Hodgkin's lymphoma of the breast: a review of 18 primary and secondary cases 2006
    2006 High levels of circulating CD34 cells, dacrocytes, clonal hematopoiesis, and JAK2 mutation differentiate myelofibrosis with myeloid metaplasia from secondary myelofibrosis associated with pulmonary hypertension 2006
    2006 Case report: Severe hemolytic disease of the newborn in a group B African-American infant delivered by a group O mother 2006
    2006 Hairy cell leukemia: A diagnosis by endoscopic ultrasound guided fine needle aspiration 2006
    2006 Severe hemolytic disease of the newborn in a group B African-American infant delivered by a group O mother. 2006
    2005 Selected case studies in hematopathology: Application of current ancillary techniques in diagnosis 2005
    2004 Digital image acquisition using a consumer-type digital camera in the anatomic pathology setting (Advances in Anatomic Pathology) 2004
    2004 Digital image acquisition using a consumer-type digital camera in the anatomic pathology setting 2004
    2004 Images in geriatric cardiology: live three-dimensional transthoracic echocardiographic assessment of right atrial thrombus. 2004
    2003 Recurrent Mantle cell lymphoma after allogeneic bone marrow transplantation presenting as isolated rectal mass 2003
    2003 Hairy cell leukemia with concurrent cryptococcus infection 2003
    2002 Safety of allogeneic Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for patients with refractory EBV-related lymphoma 2002
    2002 Copper deficiency masquerading as myelodysplastic syndrome 2002
    2002 An unusual finding of plasma cell iron 2002
    2002 Plasma cell crystalline inclusions 2002
    2002 Management of a patient with HIV infection-induced anemia and thrombocytopenia who presented with thrombotic thrombocytopenic purpura 2002
    2001 Neurolymphomatosis associated with muscle and cerebral involvement caused by natural killer cell lymphoma: A case report and review of literature 2001
    2001 Use of the internet in pathology resident training and education 2001
    2001 Fatal sickle cell crisis after granulocyte colony-stimulating factor administration [1] 2001
    2001 Topics in bone marrow biopsy pathology: Role of marrow topography in myelodysplastic syndromes and evaluation of post-treatment and post-bone marrow transplant biopsies 2001
    2001 Transesophageal echocardiographic findings of an intracavitary cardiac metastasis from a neuroendocrine thymic carcinoma 2001
    2000 A prospective trial of telepathology for intraoperative consultation (frozen sections) 2000
    2000 Fibrotic aortic stenosis in a patient with dwarfism 2000
    2000 Histologic examination of bone marrow core biopsy specimens has limited value in the diagnosis of mycobacterial and fungal infections in patients with the acquired immunodeficiency syndrome 2000
    1999 An unusual etiology of biliary hilar obstruction and the potential role of acidic fibroblast growth factor in the development of a biliary neuroma 1999
    1999 Hodgkin's and non-Hodgkin's lymphoma: spectrum of morphologic and immunophenotypic overlap. 1999
    1998 The yield of bone marrow biopsy and culture compared with blood culture in the evaluation of HIV-infected patients for mycobacterial and fungal infections 1998
    1998 An initial trial of a prototype telepathology system featuring static imaging with discrete control of the remote microscope 1998
    1997 Echocardiographic detection of intramyocardial coronary obstruction produced by pericardial hydatid cyst 1997
    1997 Ulcerated tumor mass involving the right base of the tongue 1997
    1995 Cerebral vasculitis complicating rheumatoid arthritis 1995
    1995 Usefulness of the american college of rheumatology recommendations for liver biopsy in methotrexate‐treated rheumatoid arthritis patients 1995
    1994 Ascites secondary to renal-cell carcinoma diagnosed at laparoscopy 1994
    1994 Stereotaxic core breast biopsy: Value in providing tissue for flow cytometric analysis 1994
    1994 Ultrastructural immunolabeling: A unique diagnostic tool in monoclonal light chain-related renal diseases 1994
    1993 Pleural effusion in patients with systemic cholesterol embolization 1993
    1993 Primary T-cell lymphoma of muscle in a patient infected with human immunodeficiency virus 1993
    1992 Treatment of scleromalacia perforans with dura mater grafting 1992
    1992 Metastatic adenocarcinoma of the prostate manifested as a sellar tumor 1992
    1990 Efficacy of automated biopsy guns versus conventional biopsy needles in the pygmy pig 1990
    1990 The fat overload syndrome: Successful treatment with plasma exchange 1990
    1989 inflammatory myopathy and acquired immunodeficiency syndrome 1989
    1987 Fungal endocarditis caused by Pseudallescheria (Petriellidium) boydii in an intravenous drug abuser 1987
    1987 Neutrophilic eccrine hidradenitis associated with induction chemotherapy 1987
    1986 Kaposi's sarcoma of the bone marrow 1986
    1984 Chronic Myelomonocytic Leukemia: Value of Touch Preps 1984

    Book

    Year Title Altmetric
    2013 A Quick Guide to Hematology Testing – second edition 2013
    2007 A Quick Guide to Hematology Testing 2007

    Research Overview

  • My research interests are in bone marrow topography, tissue microarrays (TMA), FISH, immuno-architecture in bone marrow and lymph nodes, needle biopsy techniques, muse models of leukemia, (in(16), FLIT3-ITD), IRESSA trial in non-small cell lung carcinomas and CD30 expression in mast cells. Other areas I did work on include digital imaging, image analysis, Web-technology and developing techniques for digital image quantification of hemophagocytosis in macrophage activation syndrome (MAS) on the bone marrow biopsies. I have collaborated extensively with UAB Comprehensive Cancer Center Investigators and other outside University Medical Centers on above research areas resulting in several peer reviewed publications.
  • Teaching Overview

  • 1976-1978 Medical Technology Students, WVU, Morgantown - 10 hr/year
    1978-1983 Pathology residents, William Beaumont Army Medical Center, El Paso, TX - 20 hr/year
    1983-1992 Pathology residents, Fitzsimmons Army Medical Center, Aurora, CO - 20 hr/year
    1993-1994 Bone Marrow Morphology course, graduate course - 6 hr/year
    Dental graduate course - 2 hr/year
    Correlative Hematopathology, UAB Medical School - 20 hr/year
    Medical Dental Optometry Pathology (504) - 6 hr/year
    Hematology course, School of Health Related Professions (SHRP) - 9.5 hr/year
    Resident and fellow teaching - 3 hr/week
    1994-1995 Bone Marrow Morphology course, graduate course - 6 hr/year
    Dental graduate course - 2 hr/year
    Correlative Hematopathology, UAB Medical School - 20 hr/year
    Medical Dental Optometry Pathology (504) - 6 hr/year
    Hematology course, School of Health Related Professions (SHRP) - 9.5 hr/year
    Resident and fellow teaching - 3 hr/week
    1995-1996 Bone Marrow Morphology course, graduate course -6 hr/year
    Dental graduate course - 2 hr/year
    Correlative Hematopathology, UAB Medical School - 20 hr/year
    Medical Dental Optometry Pathology (504) - 6 hr/year
    Hematology course, School of Health Related Professions (SHRP) - 9.5 hr/year
    Resident and fellow teaching - 3 hr/week
    1996-1997 Bone Marrow Morphology course, graduate course – 4 hr
    Correlative Hematopathology, UAB Medical School – 23 hr
    Medical Dental Optometry Pathology (504) – 3 hr
    Hematology course, School of Health Related Professions (SHRP) -
    Resident and fellow teaching - 3 hr/week (total 36-40 hr/quarter)
    1997-1998 Bone Marrow Morphology course, graduate course – 4 hr
    Dental graduate course – 3 hr
    Correlative Hematopathology, UAB Medical School – 23 hr
    Medical Dental Optometry Pathology (504) - 3 hr
    Hematology course, School of Health Related Professions (SHRP) - 3
    Resident and fellow teaching - 3 hr/week (total 36- 40 hr/quarter)
    1998-1999 Bone Marrow Morphology course, graduate course – 4 hr
    Dental graduate course – 3 hr
    Correlative Hematopathology, UAB Medical School – 20 hr
    Medical Dental Optometry Pathology (504) - 3 hr
    Hematology course, School of Health Related Professions (SHRP) - 2
    Resident and fellow teaching - 3 hr/week (total 36- 40 hr/quarter)
    1999-2000 Dental graduate course – 1 hr
    Correlative Hematopathology, UAB Medical School – 21.5 hr
    Hematology course, School of Health Related Professions (SHRP) - 5
    Resident and fellow teaching - 3 hr/week (total 36- 40 hr/quarter)
    2000-2001 Dental graduate course – 1hr
    Correlative Hematopathology, UAB Medical School – 20 hr
    Hematology course, School of Health Professions (SHR) – 5 hr
    Resident and fellow teaching – 3 hr/week (total 36-40 hr/quarter
    2001-2007 Dental graduate course – 1hr
    1993 – 2008 Correlative Hematopathology, UAB Medical School – ~ 21 hr
    1994 - Resident and fellow teaching – 3 hr/week (total 36-40 hr/quarter)
    2008 - Hem/Onc Module – UASOM MS-II, ~20 hr / year
  • Teaching Activities

  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2019) 2019
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2018) 2018
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2018) 2018
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2018) 2018
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2018) 2018
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2018) 2018
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2017) 2017
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2017) 2017
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2017) 2017
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2016) 2016
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2016) 2016
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2016) 2016
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2016) 2016
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2015) 2015
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2015) 2015
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2015) 2015
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2015) 2015
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2014) 2014
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2013) 2013
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Spring Term 2013) 2013
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Fall Term 2012) 2012
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Fall Term 2011) 2011
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Fall Term 2010) 2010
  • PCL2225 - HEMATOLOGY/ONCOLOGY (Fall Term 2009) 2009
  • PCL2225 - HEMATOLOGY / ONCOLOGY (Fall Term 2008) 2008
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2008) 2008
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2008) 2008
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2007) 2007
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2007) 2007
  • 48-408 - HEMATOPATHOLOGY (DIAGNOSTIC LYMPH NODE PATHOLOGY) (Spring Term 2007) 2007
  • Education And Training

  • West Virginia University Hospitals, Chief Resident 1978
  • M.G.M. Hospital, Internship 1973
  • M.G.M Hospital, Internship 1973
  • West Virginia University Hospital, Residency 1978
  • West Virginia Medical Center Pathology, Residency 1978
  • Atlantic City Medical Center, Residency 1975
  • Atlantic City Medical Center Pathology, Residency 1975
  • Full Name

  • Vishnu VB. Reddy