Townes Ph.D., Tim

Townes Ph.D., Tim
Professor Emeritus

Senior Scientist, Cancer Cell Biology , O'Neal Comprehensive Cancer Center
Professor - Emeritus (P), Biochemistry & Molecular Genetics , Academic Joint Departments 2016 -
Senior Scientist (C), O'Neal Comprehensive Cancer Center , School of Medicine 2019 -

Selected Publications

Academic Article

Year	Title	Altmetric
2015	Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting. Cell Reports. 12:1668-1677. 2015
2008	Gene replacement therapy for sickle cell disease and other blood disorders.. Hematology online (ASH). 193-196. 2008

Principal Investigator On

High-Throughput Screen for Small Compounds that Reactivate Fetal Hemoglobin in Adults Cells Synthesizing Sickle Hemoglobin awarded by SOUTHERN RESEARCH INSTITUTE 2013 - 2016

Human Globin Gene Regulation During Development awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2012 - 2016

Gene Replacement Therapy for Sickle Cell Disease awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2014

Erythroid Krupple-Like Factor Complexes Defined in TAP-Tagged Knockin Mice awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2007 - 2011

Investigator On

Integrated Cellular and Tissue Engineering for Ischemic Heart Disease awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2023

Myocardial Repair Using Human iPSC Derived Cardiac Muscle Patch awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2015 - 2018

DNA Damage and Oxidative Stress in Dyskeratosis Congentia: Analysis of Pathways and Therapeutic Strategies Using CRISPR and iPSC Model Systems awarded by DOD - ARMY MEDICAL RESEARCH ACQUISITION ACTIVITY 2015 - 2018

Targeted Delivery of iPS-Endothelial Cells for the Repair of Cardiovascular Injury awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2013 - 2018

Production of T Cells from Human Inducible Pluripotent Stem Cells (hIPS) Expressing a Chimeric Antigen Receptor (CAR) Against Precursor-B Leukemia Cells awarded by HYUNDAI HOPE ON WHEELS 2014 - 2016

Gene Therapy for Diamond Black Fan Anemia Using Induced Pluripotent Stem Cell Technology awarded by KAUL PEDIATRIC RESEARCH INSTITUTE 2011 - 2015

Human Heme Oxygenase-1 Gene Regulation in Renal Injury awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2008 - 2014

Toward a Cure for DBA: Creation of Patient-Specific Gene Corrected Hematopoietic Stem Cells Using Inducible Pluriopotent Stem Cell Technology awarded by DIAMOND BLACKFAN ANEMIA FOUNDATION, INC. 2012 - 2014

Private Grant awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2012 - 2013

Teaching Activities

GBSC700 - Journal Clubs (Fall Term 2019) 2019

GBSC700 - Journal Clubs (Spring Term 2019) 2019

GBSC700 - Journal Clubs (Fall Term 2018) 2018

GBSC735 - Discoveries in Mol Bio (Fall Term 2018) 2018

GBSC700 - Journal Clubs (Spring Term 2018) 2018

GBSC700 - Journal Clubs (Fall Term 2017) 2017

GBSC700 - Journal Clubs (Spring Term 2017) 2017

GBSC700 - Journal Clubs (Fall Term 2016) 2016

GBSC700 - Journal Clubs (Spring Term 2016) 2016

GBS788 - Special Topics (Fall Term 2015) 2015

GBSC700 - Journal Clubs (Fall Term 2015) 2015

GBSC700 - Journal Clubs (Spring Term 2015) 2015

GBSC701 - Seminars (Spring Term 2015) 2015

GBSC700 - Journal Clubs (Fall Term 2014) 2014

GBSC709 - Adv Stem Cell/Regen Med (Fall Term 2014) 2014

BMG726 - BMG Seminar (Spring Term 2014) 2014

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2014) 2014

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2013) 2013

BMG798 - Non-Dissertation Research (Summer Term 2013) 2013

BMG799 - Dissertation Research (Summer Term 2013) 2013

BMG726 - BMG Seminar (Spring Term 2013) 2013

BMG769 - Graduate Student Research Mtg (Spring Term 2013) 2013

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2013) 2013

BMG798 - Non-Dissertation Research (Spring Term 2013) 2013

BMG799 - Dissertation Research (Spring Term 2013) 2013

BMG769 - Graduate Student Research Mtg (Fall Term 2012) 2012

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2012) 2012

BMG798 - Non-Dissertation Research (Fall Term 2012) 2012

BMG799 - Dissertation Research (Fall Term 2012) 2012

GBS780 - BSB Lab Methods (Fall Term 2012) 2012

BMG798 - Non-Dissertation Research (Summer Term 2012) 2012

BMG799 - Dissertation Research (Summer Term 2012) 2012

BMG726 - BMG Seminar (Spring Term 2012) 2012

BMG769 - Graduate Student Research Mtg (Spring Term 2012) 2012

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2012) 2012

BMG798 - Non-Dissertation Research (Spring Term 2012) 2012

BMG799 - Dissertation Research (Spring Term 2012) 2012

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2011) 2011

BMG798 - Non-Dissertation Research (Fall Term 2011) 2011

BMG799 - Dissertation Research (Fall Term 2011) 2011

GBS780 - BSB Lab Methods (Fall Term 2011) 2011

BMG798 - Non-Dissertation Research (Summer Term 2011) 2011

BMG799 - Dissertation Research (Summer Term 2011) 2011

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2011) 2011

BMG798 - Non-Dissertation Research (Spring Term 2011) 2011

BMG799 - Dissertation Research (Spring Term 2011) 2011

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2010) 2010

BMG798 - Non-Dissertation Research (Fall Term 2010) 2010

BMG799 - Dissertation Research (Fall Term 2010) 2010

GBS780 - BSB Lab Methods (Fall Term 2010) 2010

BMG798 - Non-Dissertation Research (Summer Term 2010) 2010

BMG799 - Dissertation Research (Summer Term 2010) 2010

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2010) 2010

BMG798 - Non-Dissertation Research (Spring Term 2010) 2010

BMG799 - Dissertation Research (Spring Term 2010) 2010

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2009) 2009

BMG798 - Non-Dissertation Research (Fall Term 2009) 2009

BMG799 - Dissertation Research (Fall Term 2009) 2009

CMB713 - CMB I Biomolecules (Fall Term 2009) 2009

01-115 - CMB1 BIOMOLECULES (Fall Term 2009) 2009

BMG798 - Non-Dissertation Research (Summer Term 2009) 2009

BMG799 - Dissertation Research (Summer Term 2009) 2009

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2009) 2009

BMG798 - Non-Dissertation Research (Spring Term 2009) 2009

BMG799 - Dissertation Research (Spring Term 2009) 2009

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2008) 2008

BMG798 - Non-Dissertation Research (Fall Term 2008) 2008

BMG799 - Dissertation Research (Fall Term 2008) 2008

CMB713 - CMB I Biomolecules (Fall Term 2008) 2008

01-115 - CMB1 BIOMOLECULES (Fall Term 2008) 2008

BMG798 - Non-Dissertation Research (Summer Term 2008) 2008

BMG799 - Dissertation Research (Summer Term 2008) 2008

BMG796 - Journal Club Adv Euk Mole Biol (Spring Term 2008) 2008

BMG796 - Journal Club Adv Euk Mole Biol (Fall Term 2007) 2007

CMB713 - CMB I Biomolecules (Fall Term 2007) 2007

01-115 - CMB1 BIOMOLECULES (Fall Term 2007) 2007

Education And Training

Master of Arts in Zoology / Animal Biology, University of Tennessee System : Knoxville 2000

Doctor of Philosophy in Zoology / Animal Biology, University of Tennessee System : Knoxville 1980

Bachelor's Degree in Microbiology, University of Tennessee System : Knoxville 1973

Full Name

Tim Townes