Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Thiol-Redox Regulation in Lung Development and Vascular Remodeling.Antioxidants and Redox Signaling2019
2018 The thioredoxin reductase inhibitor auranofin induces heme oxygenase-1 in lung epithelial cells via Nrf2-dependent mechanismsAJP - Lung Cellular and Molecular Physiology.  315:L545-L552. 2018
2018 Selenium supplementation of lung epithelial cells enhances nuclear factor E2-related factor 2 (Nrf2) activation following thioredoxin reductase inhibitionRedox Biology.  19:331-338. 2018
2018 Detection of dinitrosyl iron complexes by ozone-based chemiluminescenceNitric Oxide: Biology and Chemistry.  79:57-67. 2018
2018 Aurothioglucose does not improve alveolarization or elicit sustained Nrf2 activation in C57BL/6 models of bronchopulmonary dysplasiaAJP - Lung Cellular and Molecular Physiology.  314:L736-L742. 2018
2018 Hemodynamic effects of glutathione-liganded binuclear dinitrosyl iron complex: Evidence for nitroxyl generation and modulation by Plasma AlbuminMolecular Pharmacology.  93:427-437. 2018
2018 Nitrite potentiates the vasodilatory signaling of S-nitrosothiolsNitric Oxide: Biology and Chemistry.  75:60-69. 2018
2017 miR-29b supplementation decreases expression of matrix proteins and improves alveolarization in mice exposed to maternal inflammation and neonatal hyperoxiaAJP - Lung Cellular and Molecular Physiology.  313:L339-L349. 2017
2016 Maternal high fat diet exposure is associated with increased hepcidin levels, decreased myelination, and neurobehavioral changes in male offspringBrain, Behavior, and Immunity.  58:369-378. 2016
2016 Thioredoxin reductase inhibition attenuates neonatal hyperoxic lung injury and enhances nuclear factor E2-related factor 2 activationAmerican Journal of Respiratory Cell and Molecular Biology.  55:419-428. 2016
2016 Of mice and men: Correlations between microRNA-17~92 cluster expression and promoter methylation in severe bronchopulmonary dysplasiaAJP - Lung Cellular and Molecular Physiology.  311:L981-L984. 2016
2015 Attenuation of MIR-17∼92 cluster in bronchopulmonary dysplasiaAnnals of the American Thoracic Society.  12:1506-1513. 2015
2015 DHA suppresses chronic apoptosis in the lung caused by perinatal inflammationAJP - Lung Cellular and Molecular Physiology.  309:L441-L448. 2015
2014 The thioredoxin system in neonatal lung diseaseAntioxidants and Redox Signaling.  21:1916-1925. 2014
2014 Arginase II is a target of miR-17-5p and regulates miR-17-5p expression in human pulmonary artery smooth muscle cellsAJP - Lung Cellular and Molecular Physiology.  307. 2014
2014 The thioredoxin reductase-1 inhibitor aurothioglucose attenuates lung injury and improves survival in a murine model of acute respiratory distress syndromeAntioxidants and Redox Signaling.  20:2681-2691. 2014
2014 Maternal dietary docosahexaenoic acid supplementation attenuates fetal growth restriction and enhances pulmonary function in a newborn mouse model of perinatal inflammationJournal of Nutrition.  144:258-266. 2014
2013 Neonatal hyperoxic exposure persistently alters lung secretoglobins and annexin A1BioMed Research International.  2013. 2013
2013 Thioredoxin-1 mediates hypoxia-induced pulmonary artery smooth muscle cell proliferationAJP - Lung Cellular and Molecular Physiology.  305. 2013
2013 Cyclooxygenase-2 in newborn hyperoxic lung injuryFree Radical Biology and Medicine.  61:502-511. 2013
2012 Thioredoxin reductase inhibition elicits Nrf2-mediated responses in clara cells: Implications for oxidant-induced lung injuryAntioxidants and Redox Signaling.  17:1407-1416. 2012
2012 Plasma lipid metabolites are associated with gestational age but not bronchopulmonary dysplasiaActa Paediatrica.  101. 2012
2012 Prenatal inflammation exacerbates hyperoxia-induced functional and structural changes in adult miceAJP - Regulatory, Integrative and Comparative Physiology.  303:279-290. 2012
2012 Lipopolysaccharide-induced cyclooxygenase-2 expression in mouse transformed clara cellsCellular Physiology and Biochemistry.  29:213-222. 2012
2012 Methods for the determination of plasma or tissue glutathione levelsMethods in Molecular Biology.  889:315-324. 2012
2011 Riboflavin supplementation does not attenuate hyperoxic lung injury in transgenic spc-mthGR miceExperimental Lung Research.  37:155-161. 2011
2011 Maternal docosahexaenoic acid supplementation decreases lung inflammation in hyperoxia-exposed newborn miceJournal of Nutrition.  141:214-222. 2011
2010 Thioredoxin-interacting protein inhibits hypoxia-inducible factor transcriptional activityFree Radical Biology and Medicine.  49:1361-1367. 2010
2010 Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn micePediatric Research.  67:144-149. 2010
2009 Alterations of the thioredoxin system by hyperoxia: Implications for alveolar developmentAmerican Journal of Respiratory Cell and Molecular Biology.  41:612-619. 2009
2009 Differential responses in the lungs of newborn mouse pups exposed to 85% or >95% oxygenPediatric Research.  65:33-38. 2009
2007 Thioredoxin-related mechanisms in hyperoxic lung injury in miceAmerican Journal of Respiratory Cell and Molecular Biology.  37:405-413. 2007

Education And Training

  • Doctor of Medicine, Indiana University System : Indiana University/Purdue University at Indianapolis 2000
  • The Ohio State University, Residency 2003
  • The Ohio State University, Postdoctoral Fellowship 2006
  • Full Name

  • Trent Tipple