Positions

Selected Publications

Academic Article

Year Title Altmetric
2017 Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major.  Blood Advances.  1:2421-2432. 2017
2010 Humanized mouse models of Cooley's anemia: Correct fetal-to-adult hemoglobin switching, disease onset, and disease pathology.  Annals of the New York Academy of Sciences.  1202:45-51. 2010
2009 Preclinical transfusion-dependent humanized mouse model of β thalassemia major.  Blood.  113:4763-4770. 2009
2009 Humanized mouse model of Cooley's anemia.  Journal of Biological Chemistry.  284:4889-4896. 2009
2007 JunB and JunD regulate human heme oxygenase-1 gene expression in renal epithelial cells.  Journal of Biological Chemistry.  282:6875-6886. 2007
2006 Correction of sickle cell disease by homologous recombination in embryonic stem cells.  Blood.  108:1183-1188. 2006
2004 A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.  Journal of Biological Chemistry.  279:27518-27524. 2004
2003 Correction of a mouse model of sickle cell disease: Lentiviral/ antisickling β-globin gene transduction of unmobilized, purified hematopoietic stem cells.  Blood.  102:4312-4319. 2003
2003 Nitric oxide-dependent generation of reactive species in sickle cell disease: Actin tyrosine nitration induces defective cytoskeletal polymerization.  Journal of Biological Chemistry.  278:4194-4204. 2003
2002 Correction of phenotype in a thalassemia mouse model using a nonmyeloablative marrow transplantation regimen.  Biology of Blood and Marrow Transplantation.  8:453-461. 2002
2000 Generation of novel embryonic stem cell lines from knockout-transgenic sickle cell disease mice: a new tool for therapeutic intervention.  Blood.  96. 2000
1998 Knockout-transgenic mouse models of human hemoglobinopathies.  Experimental Hematology.  26:807. 1998
1990 Human γ- To β-globin gene switching in transgenic mice.  Genes and Development.  4:380-389. 1990
1989 A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice..  Genes and Development.  3:314-323. 1989

Teaching Activities

  • GBS748 - Special Topics (Summer Term 2020) 2020
  • GBS784 - Stem Cell Biology (Spring Term 2020) 2020
  • GBSC700 - Journal Clubs (Spring Term 2020) 2020
  • GBSC742 - Student Theme Meeting Course (Spring Term 2020) 2020
  • GBS748 - Special Topics (Fall Term 2019) 2019
  • GBSC700 - Journal Clubs (Fall Term 2019) 2019
  • GBSC709 - Adv Stem Cell/Regen Med (Fall Term 2019) 2019
  • GBSC742 - Student Theme Meeting Course (Fall Term 2019) 2019
  • GBS784 - Stem Cell Biology (Spring Term 2019) 2019
  • GBSC700 - Journal Clubs (Spring Term 2019) 2019
  • GBSC742 - Student Theme Meeting Course (Spring Term 2019) 2019
  • GBSC700 - Journal Clubs (Fall Term 2018) 2018
  • GBSC709 - Adv Stem Cell/Regen Med (Fall Term 2018) 2018
  • GBSC742 - Student Theme Meeting Course (Fall Term 2018) 2018
  • GBS784 - Stem Cell Biology (Spring Term 2018) 2018
  • GBSC700 - Journal Clubs (Spring Term 2018) 2018
  • GBSC701 - Seminars (Spring Term 2018) 2018
  • GBSC701 - Seminars (Spring Term 2018) 2018
  • GBSC700 - Journal Clubs (Fall Term 2017) 2017
  • GBSC701 - Seminars (Fall Term 2017) 2017
  • GBSC701 - Seminars (Fall Term 2017) 2017
  • GBS784 - Stem Cell Biology (Spring Term 2017) 2017
  • GBSC700 - Journal Clubs (Spring Term 2017) 2017
  • GBSC701 - Seminars (Spring Term 2017) 2017
  • GBSC701 - Seminars (Spring Term 2017) 2017
  • GBSC700 - Journal Clubs (Fall Term 2016) 2016
  • GBSC701 - Seminars (Fall Term 2016) 2016
  • GBSC701 - Seminars (Fall Term 2016) 2016
  • GBSC709 - Adv Stem Cell/Regen Med (Fall Term 2016) 2016
  • GBS784 - Stem Cell Biology (Spring Term 2016) 2016
  • GBSC700 - Journal Clubs (Spring Term 2016) 2016
  • GBSC700 - Journal Clubs (Fall Term 2015) 2015
  • GBS784 - STEM CELL BIOLOGY (Spring Term 2015) 2015
  • GBS784 - Stem Cell Biology (Spring Term 2015) 2015
  • GBSC700 - Journal Clubs (Spring Term 2015) 2015
  • GBSC700 - Journal Clubs (Fall Term 2014) 2014
  • GBSC709 - Adv Stem Cell/Regen Med (Fall Term 2014) 2014
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2014) 2014
  • GBS784 - Stem Cell Biology (Spring Term 2014) 2014
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2013) 2013
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2013) 2013
  • GBS784 - Stem Cell Biology (Spring Term 2013) 2013
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2012) 2012
  • OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2012) 2012
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2012) 2012
  • GBS784 - Stem Cell Biology (Spring Term 2012) 2012
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2011) 2011
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2011) 2011
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2011) 2011
  • GBS784 - Stem Cell Biology (Spring Term 2011) 2011
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2010) 2010
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2010) 2010
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2010) 2010
  • CMB774 - CMB VII Stem Cell Biology (Spring Term 2010) 2010
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2009) 2009
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2009) 2009
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2009) 2009
  • CMB774 - CMB VII Stem Cell Biology (Spring Term 2009) 2009
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2008) 2008
  • OBHS111 - Fundamentals of Dent and Opt I (Fall Term 2008) 2008
  • BMG773 - Journal Club in Stem Cell Biol (Spring Term 2008) 2008
  • BMG798 - Non-Dissertation Research (Spring Term 2008) 2008
  • BMG799 - Dissertation Research (Spring Term 2008) 2008
  • CMB774 - CMB VII Stem Cell Biology (Spring Term 2008) 2008
  • BMG773 - Journal Club in Stem Cell Biol (Fall Term 2007) 2007
  • BMG798 - Non-Dissertation Research (Fall Term 2007) 2007
  • BMG799 - Dissertation Research (Fall Term 2007) 2007

    • Education And Training

  • Doctor of Philosophy in Microbiology, University of Alabama at Birmingham 1990
  • Bachelor of Arts in Biology, California State University System : Humboldt State University 1982
  • Bachelor of Arts in Chemistry, California State University System : Humboldt State University 1982

    • Full Name

  • Thomas Ryan