Positions

Overview

  • My lab aims to understand virus structure and the structure-function relationships involved in the processes of viral replication, including virus-host interactions, capsid structure and polynucleotide synthesis. Toward this goal, we have used structural techniques (cryo-electron microscopy, x-ray crystallography and small angle x-ray scattering) alongside biochemistry and classical virology techniques to study viral proteins from negative strand RNA viruses (NSV: influenza A, mumps, rabies virus, VSV) and retroviruses (HIV). This dual approach has been successful in producing near atomic-level snapshots of many complex protein assemblies as well as enabling a fast-track to novel biological discovery and new experimental design. Professionally, my expertise in structural biology has lead to my collaboration with investigators locally, nationally and internationally on viral, bacterial, human and murine targets.
  • Selected Publications

    Chapter

    Year Title Altmetric
    2011 Assembly of vesicular stomatitis virus.  175-192. 2011

    Research Overview

  • The targets of my current NIH funded research are to understand the processes of NSV polynucleotide synthesis from the view of the template (a complex between the viral genome and the nucleocapsid) as well as the polymerase machinery (a complex between the L protein, P protein and potentially host factors).
  • Education And Training

  • Doctor of Philosophy in Microbiology, University of Alabama at Birmingham 2002
  • Bachelor of Science or Mathematics in Biology, University of Alabama in Huntsville 1994
  • Full Name

  • Todd Green