Positions

Selected Publications

Academic Article

Year Title Altmetric
2021 Maintaining Normal Blood Pressure Across the Life Course: The JHS.Hypertension.  77:1490-1499. 2021
2021 Effect of Intensive Versus Standard Blood Pressure Control on Stroke Subtypes.Hypertension.  77:1391-1398. 2021
2021 Connecting Generations of Scientists in the Council on Hypertension Through Harriet DustanHypertension.  77:296-307. 2021
2021 Masked Uncontrolled Hypertension Is Accompanied by Increased Out-of-Clinic Aldosterone SecretionHypertension.  77:435-444. 2021
2021 Response to “Comment’s on the Story of the Silent Killer, a History of Hypertension: Its Discovery, Diagnosis, Treatment, and Debate”Current Hypertension Reports.  23. 2021
2021 Worsening Kidney Function Is the Major Mechanism of Heart Failure in Hypertension: The ALLHAT StudyJACC: Heart Failure.  9:100-111. 2021
2021 Blood pressure target in patients with hypertension and type-2 diabetes older than 65 years. Is <130/80 mmHg the right target or an excessive objective preventing from achieving the clinical goals we are aiming at? 2021
2021 Estimated GFR Variability and Risk of Cardiovascular Events and Mortality in SPRINT (Systolic Blood Pressure Intervention Trial)American Journal of Kidney Diseases2021
2021 Potential protective effects of antihypertensive treatments during the Covid-19 pandemic: from inhibitors of the renin-angiotensin system to beta-adrenergic receptor blockers 2021
2020 Concordance between Blood Pressure in the Systolic Blood Pressure Intervention Trial and in Routine Clinical PracticeJAMA Internal Medicine.  180:1655-1663. 2020
2020 Nocturnal blood pressure dipping in treated hypertensives: insights from the SPRINT trial.European Journal of Preventive Cardiology2020
2020 Association of Race/Ethnicity-Specific Changes in Antihypertensive Medication Classes Initiated Among Medicare Beneficiaries With the Eighth Joint National Committee Panel Member ReportJAMA Network Open.  3:e2025127. 2020
2020 Salt and cardiovascular disease: Insufficient evidence to recommend low sodium intakeEuropean Heart Journal.  41:3363-3373. 2020
2020 The International Society of Hypertension Guidelines 2020–a new drug treatment recommendation in the wrong direction? 2020
2020 Prevention, Diagnosis, and Management of Hypertensive Disorders of Pregnancy: a Comparison of International GuidelinesCurrent Hypertension Reports.  22. 2020
2020 The Story of the Silent Killer: A History of Hypertension: Its Discovery, Diagnosis, Treatment, and DebatesCurrent Hypertension Reports.  22. 2020
2020 Race-based and sex-based differences in bioactive lipid mediators after myocardial infarctionESC Heart Failure.  7:1700-1710. 2020
2020 Reserpine substantially lowers blood pressure in patients with refractory hypertension: A proof-of-concept studyAmerican Journal of Hypertension.  33:741-747. 2020
2020 To the EditorJAMA Internal Medicine.  180:1132-1133. 2020
2020 Weight Reduction for Obesity-Induced Heart Failure with Preserved Ejection FractionCurrent Hypertension Reports.  22. 2020
2020 Intensive systolic blood pressure control and prevention of new onset atrial fibrillation in the SPRINT study: is the association really controversial? 2020
2020 Arterial stiffness and kidney disease progression in the systolic blood pressure intervention trialClinical Nephrology.  94:26-35. 2020
2020 Obesity, Hypertension, and Bariatric SurgeryCurrent Hypertension Reports.  22. 2020
2020 Chronic hypertension in pregnancyAmerican Journal of Obstetrics and Gynecology.  222:532-541. 2020
2020 Blood pressure medication should not be routinely dosed at bedtime. We must disregard the data from the HYGIA project 2020
2020 RE Letter to the Editor: Prehypertension is associated with multiple poor maternal and fetal outcomes, by Giovanni SistiAmerican Journal of Obstetrics and Gynecology.  222:514. 2020
2020 How to deal with the occurrence of rare drug-induced adverse events: the example of sprue-like enteropathy induced by olmesartan medoxomil and other angiotensin-receptor blockers 2020
2020 Aortic blood pressure and arterial stiffness in patients with controlled resistant and non-resistant hypertensionJournal of Clinical Hypertension.  22:167-173. 2020
2020 The AJMS Celebrates # 200!American Journal of the Medical Sciences.  359:61-62. 2020
2020 The role of exercise in the reversal of IGF-1 deficiencies in microvascular rarefaction and hypertensionGeroscience.  42:141-158. 2020
2020 The Health Outcomes Prevention and Evaluation 4 (HOPE 4) project: A successful community-based intervention to lower cardiovascular risk in people with hypertension 2020
2020 Antihypertensive Medication Adherence and Confirmation of True Refractory HypertensionHypertension.  510-515. 2020
2020 Case of Episodic and Positional Hypertension: Diagnosis and TreatmentHypertension.  614-621. 2020
2020 Forty-year shifting distribution of systolic blood pressure with population hypertension treatment and controlCirculation.  1524-1531. 2020
2020 Global Blood Pressure Screening: A Wakeup CallHypertension.  318-320. 2020
2020 Orthostatic Hypotension, Cardiovascular Outcomes, and Adverse Events: Results from SPRINTHypertension.  660-667. 2020
2020 Report of the National Heart, Lung, and blood institute working group on hypertension barriers to translationHypertension.  902-917. 2020
2020 Was it optimal to drop a diuretic as a first-line choice of drug treatment in the 2020 International Society of Hypertension Guidelines? 2020
2019 Heart Failure Prevention in Older Patients Using Intensive Blood Pressure Reduction: Potential Role of DiureticsJACC: Heart Failure.  7:1032-1041. 2019
2019 State of the Art: the Not-So-Great Wall of AmericaCurrent Hypertension Reports.  21. 2019
2019 Systolic blood pressure control prevents cognitive decline and slows development of white matter lesions in the brain: the SPRINT MIND study outcomes 2019
2019 Sex Differences in Hypertension and Stroke Risk in the REGARDS Study: A Longitudinal Cohort StudyHypertension.  74:749-755. 2019
2019 The PARAGON-Heart failure trial–another disappointment for heart failure patients with hypertension and preserved ejection fraction 2019
2019 Masked uncontrolled hypertension is not attributable to medication nonadherenceHypertension.  74:652-659. 2019
2019 Association of intensive vs standard blood pressure control with cerebral white matter lesions 2019
2019 Effect of Intensive Blood Pressure Reduction on Left Ventricular Mass, Structure, Function, and Fibrosis in the SPRINT-HEARTHypertension.  74:276-284. 2019
2019 The PARAGON Heart Failure trial–ongoing investigation of the angiotensin receptor antagonist/neprilysin inhibitor sacubitril/valsartan in heart failure patients with hypertension and preserved ejection fraction 2019
2019 Six-Month Results of Treatment-Blinded Medication Titration for Hypertension Control After Randomization to Endovascular Ultrasound Renal Denervation or a Sham Procedure in the RADIANCE-HTN SOLO TrialCirculation.  139:2542-2553. 2019
2019 Need for multiple risk reduction strategies in clinical trials enrolling high risk patients - FOURIER investigating PCSK-9 inhibitor to lower cholesterol revisited 2019
2019 Epicardial Adipose Tissue and Cardiovascular DiseaseCurrent Hypertension Reports.  21. 2019
2019 Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertensionFree Radical Biology and Medicine.  134:343-349. 2019
2019 Sustained blood pressure control and coronary heart disease, stroke, heart failure, and mortality: An observational analysis of ALLHATJournal of Clinical Hypertension.  21:451-459. 2019
2019 Urinary biomarkers of tubular damage are associated with mortality but not cardiovascular risk among systolic blood pressure intervention trial participants with chronic kidney diseaseAmerican Journal of Nephrology.  49:346-355. 2019
2019 Treatment of Resistant and Refractory HypertensionCirculation Research.  124:1061-1070. 2019
2019 Will we ever use angiotensin receptor neprilysin inhibition (ARNi) for the treatment of hypertension? 2019
2019 Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial 2019
2019 New data on antihypertensive drugs and risk of cancer: should we worry? 2019
2019 Induced pluripotent stem cell-derived endothelial cells attenuate lipopolysaccharide-induced acute lung injury 2019
2019 Lower blood pressure thresholds raise the bar in pregnancyCirculation Research.  125:195-197. 2019
2019 Out-of-Clinic Sympathetic Activity Is Increased in Patients with Masked Uncontrolled HypertensionHypertension.  73:132-141. 2019
2018 PTH, FGF23, and intensive blood pressure lowering in chronic kidney disease participants in SPRINTClinical Journal of the American Society of Nephrology.  13:1816-1824. 2018
2018 Obesity and Pulmonary HypertensionCurrent Hypertension Reports.  20. 2018
2018 2018 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension 2018
2018 Association of Clinical and Social Factors with Excess Hypertension Risk in Black Compared with White US Adults 2018
2018 Novel Medical Treatments for Hypertension and Related ComorbiditiesCurrent Hypertension Reports.  20. 2018
2018 Prognostic value of myocardial perfusion imaging performed pre-renal transplantation: post-transplantation follow-up and outcomes 2018
2018 Intensive blood pressure lowering prevents mild cognitive impairment and possible dementia and slows development of white matter lesions in brain: the SPRINT Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study 2018
2018 Take a blood pressure pill or benefit from renal denervation?European Heart Journal.  39:3010-3012. 2018
2018 Visceral Adipose Tissue Accumulation and Residual Cardiovascular RiskCurrent Hypertension Reports.  20. 2018
2018 Final Farewell to Alberto Zanchetti MD.European Heart Journal.  39:2616-2617. 2018
2018 Renal denervation achieved by endovascular delivery of ultrasound in RADIANCE-HTN SOLO or by radiofrequency energy in SPYRAL HTN-OFF and SPYRAL-ON lowers blood pressure 2018
2018 Case of refractory hypertension controlled after aortic and mitral valve replacement and coronary artery bypass graftingHypertension.  72:3-9. 2018
2018 In memoriam: Alberto Zanchetti. 2018
2018 O-linked β-N-acetylglucosamine modification of A20 enhances the inhibition of NF-κB (nuclear factor-κB) activation and elicits vascular protection after acute endoluminal arterial injury 2018
2018 Blood pressure measurement in SPRINT (Systolic Blood Pressure Intervention Trial)Hypertension.  71:848-857. 2018
2018 Long-term efficacy and tolerability of azilsartan medoxomil/chlorthalidone vs olmesartan medoxomil/hydrochlorothiazide in chronic kidney diseaseJournal of Clinical Hypertension.  20:694-702. 2018
2018 New 2017 American Heart Association and American College of Cardiology guideline for hypertension in the adults: major paradigm shifts, but will they help to fight against the hypertension disease burden? 2018
2018 Accuracy of blood pressure measurement devices in pregnancy: A systematic review of validation studiesHypertension.  71:326-335. 2018
2018 VEGF nanoparticles repair the heart after myocardial infarction 2018
2018 Challenges in oscillometric blood pressure measurement in atrial fibrillation: looking for practical solutions 2018
2018 Impact of intensive versus standard blood pressure management by tertiles of blood pressure in SPRINT (Systolic Blood Pressure Intervention Trial)Hypertension.  71:1064-1074. 2018
2018 Refractory hypertension is not attributable to intravascular fluid retention as determined by intracardiac volumesHypertension.  72:343-349. 2018
2018 Sprinting toward the optimal blood pressure target for hypertensive patientsCirculation Research.  123:531-534. 2018
2017 Renal denervation in hypertension: is it the end or the beginning of a SPYRAL? 2017
2017 Masked HypertensionCurrent Hypertension Reports.  19. 2017
2017 Treatment strategies for comorbid conditions lower residual risk in patients with treated hypertension: FOURIER and other randomized outcome trials 2017
2017 Cognitive Function and Kidney Disease: Baseline Data From the Systolic Blood Pressure Intervention Trial (SPRINT)American Journal of Kidney Diseases.  70:357-367. 2017
2017 Regression of Left Ventricular Mass After Bariatric SurgeryCurrent Hypertension Reports.  19. 2017
2017 White-Coat Effect Is Uncommon in Patients with Refractory HypertensionHypertension.  70:645-651. 2017
2017 Incident cardiovascular disease among adults with blood pressure <140/90 mm HgCirculation.  136:798-812. 2017
2017 Hypertension in Women: Recent Advances and Lingering QuestionsHypertension.  70:19-26. 2017
2017 The INTERSTROKE Study: hypertension is by far the most important modifiable risk factor for stroke 2017
2017 11-beta dehydrogenase type 2 activity is not reduced in treatment resistant hypertensionAmerican Journal of Hypertension.  30:518-523. 2017
2017 Distinctive Risk Factors and Phenotype of Younger Patients with Resistant Hypertension: Age is RelevantHypertension.  69:827-835. 2017
2017 Obesity-Associated Hypertension: the Upcoming Phenotype in African-American WomenCurrent Hypertension Reports.  19. 2017
2017 Effect of Intensive Blood Pressure Treatment on Heart Failure Events in the Systolic Blood Pressure Reduction Intervention TrialCirculation: Heart Failure.  10. 2017
2017 Hypertension and Its Complications in a Young Man with Autoimmune DiseaseHypertension.  69:536-544. 2017
2017 The INTERSALT Study and the complex relationship between salt intake and blood pressure 2017
2017 The technical report on sodiumintake and cardiovascular disease in low- and middleincome countries by the joint working group of theWorld Heart Federation, the European Society of Hypertension and the European Public Health AssociationEuropean Heart Journal.  38:712-719. 2017
2017 On-Treatment Blood Pressure and Cardiovascular Outcomes in Older Adults with Isolated Systolic HypertensionHypertension.  69:220-227. 2017
2017 Pathophysiology and Potential Non-Pharmacologic Treatments of Obesity or Kidney Disease Associated Refractory HypertensionCurrent Hypertension Reports.  19. 2017
2017 The Global Burden of Disease Study 2015 and Blood Pressure 2017
2017 Association between chronic kidney disease and cancer mortality: A report from the ALLHATClinical Nephrology.  87:11-20. 2017
2017 Association of 3 different antihypertensive medications with hip and pelvic fracture risk in older adults secondary analysis of a randomized clinical trialJAMA Internal Medicine.  177:67-76. 2017
2016 Smad3-mSin3A-HDAC1 Complex is Required for TGF-β1-Induced Transcriptional Inhibition of PPARγ in Mouse Cardiac FibroblastsCellular Physiology and Biochemistry.  40:908-920. 2016
2016 Blood Pressure in 2016: increased impact factor and change of editors 2016
2016 Should Patients with Cardiovascular Risk Factors Receive Intensive Treatment of Hypertension to <120/80 mm Hg Target?: A Protagonist View from the SPRINT Trial (Systolic Blood Pressure Intervention Trial)Circulation.  134:1308-1310. 2016
2016 BP Targets in Hypertension: What Should We Do Now That SPRINT Is Out?Current Cardiology Reports.  18. 2016
2016 Body Mass Index Predicts 24-Hour Urinary Aldosterone Levels in Patients with Resistant HypertensionHypertension.  68:995-1003. 2016
2016 The polypill: an emerging treatment alternative for secondary prevention of cardiovascular disease 2016
2016 The effects of urate lowering therapy on inflammation, endothelial function, and blood pressure (SURPHER) study design and rationaleContemporary Clinical Trials.  50:238-244. 2016
2016 The Association Between Antihypertensive Medication Nonadherence and Visit-to-Visit Variability of Blood Pressure: Findings From the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack TrialHypertension.  68:39-45. 2016
2016 Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged ≥75 years a randomized clinical trial 2016
2016 Refractory hypertension: A novel phenotype of antihypertensive treatment failureHypertension.  67:1085-1092. 2016
2016 Treatment of Hypertension in Patients with Coronary Artery Disease. A Case-Based Summary of the 2015 AHA/ACC/ASH Scientific StatementAmerican Journal of Medicine.  129:372-378. 2016
2016 CardioPulse. The SPRINT trial resultsEuropean Heart Journal.  37:924-927. 2016
2016 The SPRINT trial resultsEuropean Heart Journal.  37:925-927. 2016
2016 Visit-to-visit variability of BP and CKD outcomes: Results from the ALLHATClinical Journal of the American Society of Nephrology.  11:471-480. 2016
2016 Patterns and Correlates of Baseline Thiazide-Type Diuretic Prescription in the Systolic Blood Pressure Intervention TrialHypertension.  67:550-555. 2016
2016 Targeted delivery of human iPS-ECs overexpressing IL-8 receptors inhibits neointimal and inflammatory responses to vascular injury in the rat 2016
2016 SPS3 Evidence Supports Intensive Blood Pressure ControlCirculation.  133:552-554. 2016
2016 SPRINT Trial Results: Latest News in Hypertension ManagementHypertension.  67:263-265. 2016
2016 The J-curve phenomenon revisited again: SPRINT outcomes favor target systolic blood pressure below 120 mmHg 2016
2016 Impact of renal denervation on patients with obstructive sleep apnea and resistant hypertension – Insights from the SYMPLICITY HTN-3 trialCirculation Journal.  80:1404-1412. 2016
2016 Should Antihypertensive Treatment Recommendations Differ in Patients with and Without Coronary Heart Disease? (from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial [ALLHAT])American Journal of Cardiology.  117:105-115. 2016
2015 Visit-to-visit variability of blood pressure and coronary heart disease, stroke, heart failure, and mortality a cohort studyAnnals of Internal Medicine.  163:329-338. 2015
2015 Estrogen and cardiovascular disease: Is timing everything?American Journal of the Medical Sciences.  350:27-35. 2015
2015 Apparent treatment-resistant hypertension among individuals with history of stroke or transient ischemic attackAmerican Journal of Medicine.  128:707-714.e2. 2015
2015 Treatment of Hypertension in Patients with Coronary Artery Disease: A Scientific Statement from the American Heart Association, American College of Cardiology, and American Society of HypertensionHypertension.  65:1372-1407. 2015
2015 Treatment of hypertension in patients with coronary artery disease: A scientific statement from the american heart association, american college of cardiology, and american society of hypertensionCirculation.  131:e435-e470. 2015
2015 Regional Heterogeneity in 3D Myocardial Shortening in Hypertensive Left Ventricular Hypertrophy: A Cardiovascular CMR Tagging Substudy to the Life Study.Journal of Biomedical Science and Engineering.  8:213-225. 2015
2015 Predictors of blood pressure response in the SYMPLICITY HTN-3 trialEuropean Heart Journal.  36:219-227. 2015
2015 New Approaches in the Treatment of HypertensionCirculation Research.  116:1074-1095. 2015
2015 Refractory hypertension: Evidence of heightened sympathetic activity as a cause of antihypertensive treatment failureHypertension.  66:126-133. 2015
2014 Triple-combination treatment with olmesartan medoxomil/amlodipine/ hydrochlorothiazide in hispanic/latino patients with hypertension: The trinity studyEthnicity and Disease.  24:41-47. 2014
2014 Update on Clinical Guidelines for Treatment of HypertensionCurrent Cardiovascular Risk Reports.  8:1-8. 2014
2014 The design and rationale of a multicenter clinical trial comparing two strategies for control of systolic blood pressure: The systolic blood pressure intervention trial (SPRINT)Clinical Trials.  11:532-546. 2014
2014 Guidelines for managing high blood pressure - Reply 2014
2014 Determination of prevalence, risk factors, and comorbidities in a large, population-based cohortHypertension.  63:451-458. 2014
2014 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8) 2014
2014 Hypertension Management by Practice Guidelines 2014
2014 2014 evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the eighth joint national committee (JNC 8) 2014
2014 Chlorthalidone versus hydrochlorothiazide in hypertension treatment: Do we have the evidence to decide?American Journal of Kidney Diseases.  63:387-389. 2014
2014 Effect of chlorthalidone, amlodipine, and lisinopril on visit-to-visit variability of blood pressure: Results from the antihypertensive and lipid-lowering treatment to prevent heart attack trialJournal of Clinical Hypertension.  16:323-330. 2014
2014 Estrogen effects on vascular inflammation are age dependent: Role of estrogen receptors 2014
2014 Incident ESRD and treatment-resistant hypertension: The reasons for geographic and racial differences in stroke (REGARDS) studyAmerican Journal of Kidney Diseases.  63:781-788. 2014
2014 Proceedings from Duke resistant hypertension think tankAmerican Heart Journal.  167. 2014
2014 Renal denervation in treatment-resistant hypertension-Oslo RDN, Symplicity HTN-3 and INSPiRED randomized trials 2014
2014 Response to should more significance be granted to medication response to antihypertensives in patients with resistant hypertension?Hypertension.  63. 2014
2014 Targeted delivery of pulmonary arterial endothelial cells overexpressing interleukin-8 receptors attenuates monocrotaline-induced pulmonary vascular remodeling 2014
2014 Trends in hypertension prevalence, awareness, treatment, and control among us adults 80 years and older, 1988-2010Journal of Clinical Hypertension.  16:270-276. 2014
2014 Updated guidelines for management of high blood pressure in JapanHypertension Research.  37:484-487. 2014
2013 Author Response to Lipid-Lowering in African Americans in ALLHAT-Optimism Bias?Journal of Clinical Hypertension.  15:941-941. 2013
2013 Revisiting the pre-hypertension debate: Increasing evidence for treatment-or not 2013
2013 Risk of Hospitalized Gastrointestinal Bleeding in Persons Randomized to Diuretic, ACE-Inhibitor, or Calcium-Channel Blocker in ALLHATJournal of Clinical Hypertension.  15:825-832. 2013
2013 The Human Side of Failed Hypertension TreatmentJournal of Clinical Hypertension.  15:762-764. 2013
2013 Blood pressure lowering effect of renal sympathetic denervation or placebo? - Building expectations for Symplicity-HTN 3 2013
2013 Prevalence of apparent treatment-resistant hypertension among individuals with CKDClinical Journal of the American Society of Nephrology.  8:1583-1590. 2013
2013 2013 European society of hypertension/European society of cardiology hypertension guidelines 2013
2013 Long-term follow-up of moderately hypercholesterolemic hypertensive patients following randomization to pravastatin vs usual care: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT-LLT)Journal of Clinical Hypertension.  15:542-554. 2013
2013 Olmesartan/amlodipine/hydrochlorothiazide in obese participants with hypertension: A TRINITY subanalysisJournal of Clinical Hypertension.  15:584-592. 2013
2013 Ovarian hormones and vascular diseaseCurrent Opinion in Cardiology.  28:411-416. 2013
2013 Primary cardiovascular prevention by Mediterranean diet - The PREDIMED trial 2013
2013 Endothelial cells overexpressing IL-8 receptor reduce cardiac remodeling and dysfunction following myocardial infarction 2013
2013 Mortality and morbidity during and after antihypertensive and lipid-lowering treatment to prevent heart attack trial: Results by sexHypertension.  61:977-986. 2013
2013 Changes in cardiovascular risk associated with phentermine and topiramate extended-release in participants with comorbidities and a body mass index ≥27 kg/m2American Journal of Cardiology.  111:1131-1138. 2013
2013 Reply to Visit-to-Visit Blood Pressure Variation: Time to Reanalyze All The Data From the TROPHY StudyJournal of Clinical Hypertension.  15:301. 2013
2013 Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiencyEuropean Heart Journal.  34:676-683. 2013
2013 Association Between Antihypertensive Medication Adherence and Visit-to-Visit Variability of Blood PressureJournal of Clinical Hypertension.  15:112-117. 2013
2013 Randomized Study of Antihypertensive Efficacy and Safety of Combination Aliskiren/Valsartan vs Valsartan Monotherapy in Hypertensive Participants With Type 2 Diabetes MellitusJournal of Clinical Hypertension.  15:92-100. 2013
2013 Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronismChest.  143:978-983. 2013
2012 Angiotensin receptor - Neprilysin inhibiton (ARNI) A novel therapeutic concept for management of hypertension and heart failure 2012
2012 Blood Pressure Measurement Device, Number and Timing of Visits, and Intra-Individual Visit-to-Visit Variability of Blood PressureJournal of Clinical Hypertension.  14:744-750. 2012
2012 Direct renin inhibitors in hypertension Approaching the moment of truth 2012
2012 Acute O-GlcNAcylation prevents inflammation-induced vascular dysfunction 2012
2012 Catheter-based renal denervation for resistant hypertension: Rationale and design of the SYMPLICITY HTN-3 trial 2012
2012 J Curve in HypertensionCurrent Cardiovascular Risk Reports.  6:281-290. 2012
2012 Triple-Combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: the TRINITY randomized, double-blind, 12-week, parallel-group study.American Journal of Cardiovascular Drugs.  12:233-243. 2012
2012 Triple-combination therapy with olmesartan, amlodipine, and hydrochlorothiazide in black and non-black study participants with hypertension: The trinity randomized, double-blind, 12-week, parallel-group studyAmerican Journal of Cardiovascular Drugs.  12:233-243. 2012
2012 Long-Term renal and cardiovascular outcomes in antihypertensive and Lipid-Lowering treatment to prevent heart attack trial (ALLHAT) participants by baseline estimated GFRClinical Journal of the American Society of Nephrology.  7:989-1002. 2012
2012 Clinical significance of incident hypokalemia and hyperkalemia in treated hypertensive patients in the antihypertensive and lipid-lowering treatment to prevent heart attack trialHypertension.  59:926-933. 2012
2012 Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure 2012
2012 Endothelial cells overexpressing interleukin-8 receptors reduce inflammatory and neointimal responses to arterial injuryCirculation.  125:1533-1541. 2012
2012 Long-Term Efficacy and Safety of Triple-Combination Therapy With Olmesartan Medoxomil and Amlodipine Besylate and Hydrochlorothiazide for HypertensionJournal of Clinical Hypertension.  14:149-157. 2012
2012 Long-term effects of incident diabetes mellitus on cardiovascular outcomes in people treated for hypertension the ALLHAT diabetes extension studyCirculation: Cardiovascular Quality and Outcomes.  5:153-162. 2012
2012 Antiplatelet therapy for transient ischemic attackJournal of Clinical Hypertension.  14:103-111. 2012
2012 Increased time varying heart rate and cardiovascular risk in hypertension Benefit of selective I (f) channel inhibitor? 2012
2012 Mortality and morbidity during and after the antihypertensive and lipid-lowering treatment to prevent heart attack trialJournal of Clinical Hypertension.  14:20-31. 2012
2012 Prevalence and Correlates of Low Medication Adherence in Apparent Treatment-Resistant HypertensionJournal of Clinical Hypertension.  14:694-700. 2012
2012 Refractory hypertension: Definition, prevalence, and patient characteristicsJournal of Clinical Hypertension.  14:7-12. 2012
2012 Renal sympathetic denervation for treatment of hypertensionCurrent Treatment Options in Cardiovascular Medicine.  14:127-135. 2012
2012 Within-Visit Variability of Blood Pressure and All-Cause and Cardiovascular Mortality Among US AdultsJournal of Clinical Hypertension.  14:165-171. 2012
2011 24-Hour Efficacy and Safety of Triple-Combination Therapy With Olmesartan, Amlodipine, and Hydrochlorothiazide: The TRINITY Ambulatory Blood Pressure SubstudyJournal of Clinical Hypertension.  13:873-880. 2011
2011 An appropriate SCORE to assess cardiovascular risk in hypertension? 2011
2011 Can catheter-based renal denervation be used safely and effectively to substantially reduce blood pressure in treatment-resistant hypertensive patients?Current Cardiology Reports.  13:478-480. 2011
2011 Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling 2011
2011 Long-term follow-up of participants with heart failure in the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT)Circulation.  124:1811-1818. 2011
2011 Renal nerve ablation: Emerging role in therapeutics 2011
2011 High mortality explained by mildly elevated blood pressure in Scandinavian adolescent conscripts A plea for early drug treatment? 2011
2011 Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone 2011
2011 Response to intervisit blood pressure variability and outcome: Is heart rate a missing confounder?Hypertension.  58. 2011
2011 ACCF/AHA 2011 expert consensus document on hypertension in the elderly: A report of the american college of cardiology foundation task force on clinical expert consensus documentsCirculation.  123:2434-2506. 2011
2011 The role of ambulatory blood pressure monitoring compared with clinic and home blood pressure measures in evaluating moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapyBlood Pressure Monitoring.  16:87-95. 2011
2011 Treatment of high blood pressure in acute stroke - The SCAST Study 2011
2011 Effectiveness-based guidelines for the prevention of cardiovascular disease in women-2011 update: A Guideline from the American Heart AssociationCirculation.  123:1243-1262. 2011
2011 The relationship between visit-to-visit variability in systolic blood pressure and all-cause mortality in the general population: Findings from NHANES III, 1988 to 1994Hypertension.  57:160-166. 2011
2011 Antihypertensive therapy and cancer risks? 2011
2010 Cardiovascular risks in HIV patients 2010
2010 Comparison of the antihypertensive efficacy of irbesartan/HCTZ and valsartan/HCTZ combination therapy: Impact of age and genderClinical and experimental hypertension.  32:499-503. 2010
2010 Have the renin-angiotensin-aldosterone system perturbations in cardiovascular disease been exhausted?Current Cardiology Reports.  12:450-463. 2010
2010 Efficacy of an olmesartan medoxomil-based treatment algorithm in patients stratified by age, race, or sexJournal of Clinical Hypertension.  12:3-13. 2010
2010 Triple therapy with olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide in adult patients with hypertension: The TRINITY multicenter, randomized, double-blind, 12-week, parallel-group study 2010
2010 A stitch saves time and lowers blood pressureCurrent Hypertension Reports.  12:146-148. 2010
2010 C-reactive protein-mediated vascular injury requires complement 2010
2010 Prevention of Microalbuminuria in Patients With Type 2 Diabetes: What Do We Know?Journal of Clinical Hypertension.  12:422-430. 2010
2010 The transcription factor ETS-1 mediates proinflammatory responses and neointima formation in carotid artery endoluminal vascular injuryHypertension.  55:1381-1388. 2010
2010 Rapid reversal of left ventricular hypertrophy and intracardiac volume overload in patients with resistant hypertension and hyperaldosteronism: A prospective clinical studyHypertension.  55:1137-1142. 2010
2010 Editorial: Blood pressure and migration 2010
2010 Editorial: Hypertension research into the new millennium 2010
2010 Effect of intensive versus standard blood pressure lowering on diastolic function in patients with uncontrolled hypertension and diastolic dysfunctionHypertension.  55:241-248. 2010
2010 Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart 2010
2010 Angiotensin receptor blockers and cancer - Relationship dismissed by VALUE data while waiting for EMA and FDA reports 2010
2010 Editorial: Blood Pressure celebrates 20 years of dedication to Nordic hypertension research 2010
2010 Editorial: Blood pressure variability: Emerging role in risk assessment and therapeutics 2010
2010 Impact of olmesartan on blood pressure, endothelial function, and cardiovascular outcomesIntegrated Blood Pressure Control.  3:113-123. 2010
2009 Does GISSI-AF change the concept of using RAS inhibitors in the primary prevention of atrial fibrillation in hypertensive patients? 2009
2009 The J-curve phenomenon revisited 2009
2009 Editorial: Critical aspects in hypertension diagnosis and treatment 2009
2009 Editorial: Should we treat prehypertension? 2009
2009 Predictors of cardiovascular events in patients with hypertension and left ventricular hypertrophy: The Losartan Intervention for Endpoint reduction in hypertension study 2009
2009 Reduction of blood pressure in patients with treatment-resistant hypertensionExpert Opinion on Pharmacotherapy.  10:2959-2971. 2009
2009 Safety and tolerability of fixed-dose irbesartanhydrochlorothiazide for rapid control of severe hypertensionClinical and experimental hypertension.  31:572-584. 2009
2009 Subgroup analyses of an efficacy and safety study of concomitant administration of amlodipine besylate and olmesartan medoxomil: Evaluation by baseline hypertension stage and prior antihypertensive medication useJournal of Cardiovascular Pharmacology.  54:427-436. 2009
2009 ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analyses: ReplyArchives of Internal Medicine.  169:1810-1811. 2009
2009 Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: Results from a randomized trialHypertension.  54:475-481. 2009
2009 Hypertension in the ElderlyClinics in Geriatric Medicine.  25:391-412. 2009
2009 ONTARGET, TRANSCEND and PROFESS - Clarifying, confusing or misleading? 2009
2009 ASH Position Paper: Dietary approaches to lower blood pressure.Journal of Clinical Hypertension.  11:358-368. 2009
2009 ALLHAT findings revisited in the context of subsequent analyses, other trials, and meta-analysesArchives of Internal Medicine.  169:832-842. 2009
2009 Hormone therapy of premature ovarian failure the case for "natural" estrogenHypertension.  53:745-746. 2009
2009 Loss of Thy-1 inhibits alveolar development in the newborn mouse lung 2009
2009 Estrogen and mechanisms of vascular protection 2009
2009 A true champion of Hungarian kidney research and nephrology education--tribute to László Rosivall.Acta Physiologica Hungarica.  96:375-382. 2009
2009 Critical aspects in hypertension diagnosis and treatment 2009
2009 Efficacy and safety of long-term treatment with the combination of amlodipine besylate and olmesartan medoxomil in patients with hypertensionJournal of Clinical Hypertension.  11:475-482. 2009
2009 Prognostic importance of hemoglobin in hypertensive patients with electrocardiographic left ventricular hypertrophy: The Losartan Intervention For End point reduction in hypertension (LIFE) studyAmerican Heart Journal.  157:177-184. 2009
2009 Protein O-GlcNAcylation: A new signaling paradigm for the cardiovascular system 2009
2008 Benefits of hypertension management in diabetes: An opportunity not to be missed 2008
2008 Combining RAAS and calcium channel blockade: ACCOMPLISH in perspective 2008
2008 More focus on therapeutic targets and improved tolerability in hypertension 2008
2008 Aliskiren and valsartan in stage 2 hypertension: Subgroup analysis of a randomized, double-blind studyAdvances in Therapy.  25:1288-1302. 2008
2008 ASH position paper: Treatment of hypertension in patients with diabetes - An updateJournal of Clinical Hypertension.  10:707-713. 2008
2008 Hypertension in womenInternational Journal of Atherosclerosis.  3:138-145. 2008
2008 Management of older hypertensive patients 2008
2008 More focus on therapeutic targets and improved tolerability in hypertension. 2008
2008 Results of an olmesartan medoxomil-based treatment regimen in hypertensive patientsJournal of Clinical Hypertension.  10:911-921. 2008
2008 Renin Inhibitors: Novel Agents for Renoprotection or a Better Angiotensin Receptor Blocker for Blood Pressure Lowering?Cardiology Clinics.  26:527-535. 2008
2008 Role of oxygen availability in CFTR expression and functionAmerican Journal of Respiratory Cell and Molecular Biology.  39:514-521. 2008
2008 Renin inhibition: Should it supplant ACE inhibitors and ARBS in high risk patients?Current Opinion in Nephrology and Hypertension.  17:484-490. 2008
2008 More is less? Optimal combination therapy for adequate blood pressure lowering in hypertension 2008
2008 Marked regional left ventricular heterogeneity in hypertensive left ventricular hypertrophy patients: A losartan intervention for endpoint reduction in hypertension (LIFE) cardiovascular magnetic resonance and echocardiographic substudyHypertension.  52:279-286. 2008
2008 A stunning day in hypertension research - Results of ONTARGET, ACCOMPLISH and HYVET 2008
2008 Urgent need to address quality control issues of out-of-office blood pressure measurement and patient risk assessment 2008
2008 Increased protein O-GlcNAc modification inhibits inflammatory and neointimal responses to acute endoluminal arterial injury 2008
2008 Thiazide-induced dysglycemia: Call for research from a working group from the national heart, lung, and blood instituteHypertension.  52:30-36. 2008
2008 Transforming growth factor-β signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung 2008
2008 Characterization of resistant hypertension: Association between resistant hypertension, aldosterone, and persistent intravascular volume expansionArchives of Internal Medicine.  168:1159-1164. 2008
2008 Achieving better blood pressure control 2008
2008 Achieving better blood pressure control. 2008
2008 Beyond brachial pressure effect.Current Hypertension Reports.  10:213-215. 2008
2008 A double-blind, randomized study evaluating losartan potassium monotherapy or in combination with hydrochlorothiazide versus placebo in obese patients with hypertensionCurrent Medical Research and Opinion.  24:1101-1114. 2008
2008 Effects of losartan in women with hypertension and left ventricular hypertrophy: Results from the Losartan Intervention For Endpoint reduction in hypertension studyHypertension.  51:1103-1108. 2008
2008 Mechanisms and treatment of resistant hypertensionJournal of Clinical Hypertension.  10:239-244. 2008
2008 Atrial natriuretic peptide inhibits transforming growth factor β-induced Smad signaling and myofibroblast transformation in mouse cardiac fibroblastsCirculation Research.  102:185-192. 2008
2008 Relation of dietary salt and aldosterone to urinary protein excretion in subjects with resistant hypertensionHypertension.  51:339-344. 2008
2008 Exaggerated neointima formation in human C-reactive protein transgenic mice is IgG Fc receptor type I (FcγRI)-dependentAmerican Journal of Pathology.  172:22-30. 2008
2007 Ambulatory blood pressure adds to explaining benefits of AT-1 receptor blockade in the treatment of left ventricular hypertrophy 2007
2007 Hypertension and cardiovascular disease: Is arterial stiffness the heart of the matter 2007
2007 New ESH/ESC Guidelines signal progress in hypertension management 2007
2007 Blood pressure control - Slowly getting there through new strategies? 2007
2007 The role of endothelin-1 in human hypertensionClinical Hemorheology and Microcirculation.  37:157-178. 2007
2007 Are current guidelines optimal for treatment of blood pressure in patients with coronary artery disease?Current Hypertension Reports.  9:211-213. 2007
2007 Estrogen modulates TNF-α-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-β activation 2007
2007 Mechanisms and treatment of resistant hypertensionArquivos Brasileiros de Cardiologia.  88. 2007
2007 Documentation of endpoint prevention with combination therapy in hypertension is urgently needed 2007
2007 Aliskiren and valsartan for antihypertensive therapyACC Cardiosource Review Journal.  16:68. 2007
2007 The ALLHAT study revisited: do newer data from this trial and others indicate changes in treatment guidelines?Journal of Clinical Hypertension.  9:372-380. 2007
2007 Treatment of hypertension in the prevention and management of ischemic heart disease: A scientific statement from the American Heart Association council for high blood pressure research and the councils on clinical cardiology and epidemiology and preventionCirculation.  115:2761-2788. 2007
2007 Evidence-based guidelines for cardiovascular disease prevention in women: 2007 UpdateCirculation.  115:1481-1501. 2007
2007 Blood pressure reduction and antihypertensive medication use in the losartan intervention for endpoint reduction in hypertension (LIFE) study in patients with hypertension and left ventricular hypertrophyCurrent Medical Research and Opinion.  23:259-270. 2007
2007 ANP signaling inhibits TGF-β-induced Smad2 and Smad3 nuclear translocation and extracellular matrix expression in rat pulmonary arterial smooth muscle cells 2007
2007 Comparison of increasing doses of olmesartan medoxomil, losartan potassium, and valsartan in patients with essential hypertension.Journal of Clinical Hypertension.  9:187-195. 2007
2007 Renin inhibitors in the management of hypertension.Journal of Clinical Hypertension.  9:706-707. 2007
2006 Beta-blockers as sub-optimal treatment for hypertension: Time for first-line therapy revision? 2006
2006 The question of whether diabetes and its cardiovascular risks can be prevented: A realistic DREAM? 2006
2006 Is there a new treatment for hypertensive disease in the horizon? Role of soluble guanylate cyclaseHypertension.  48:822-823. 2006
2006 Women and hypertension: What did we learn from the Women's Health Initiative?Cardiology in Review.  14:267-275. 2006
2006 Phosphatidylinositol-3-kinase signaling mediates vascular smooth muscle cell expression of periostin in vivo and in vitroAtherosclerosis.  188:292-300. 2006
2006 Eplerenone prevents adverse cardiac remodelling induced by pressure overload in atrial natriuretic peptide-null miceClinical and Experimental Pharmacology and Physiology.  33:773-779. 2006
2006 Pulsology rediscovered: Commentary on the Conduit Artery Function Evaluation (CAFE) studyCirculation.  113:1162-1163. 2006
2006 Dominant negative mutation of the TGF-β eceptor blocks hypoxia-induced pulmonary vascular remodeling 2006
2006 American Society of Hypertension, Inc
Leadership MessageJournal of Clinical Hypertension.  8:904-905. 2006
2006 Efficacy and Safety of Irbesartan/HCTZ Combination Therapy As Initial Treatment for Rapid Control of Severe HypertensionJournal of Clinical Hypertension.  8:850-859. 2006
2006 Incidence and predictors of angioedema in elderly hypertensive patients at high risk for cardiovascular disease: a report from the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).Journal of Clinical Hypertension.  8. 2006
2006 Metabolite ligands of estrogen receptor-β reduce primate coronary hyperreactivity 2006
2006 Treatment of isolated systolic hypertension in diabetes mellitus type 2 2006
2005 HypertensionHypertension2005
2005 Targeting the renin-angiotensin system for the reduction of cardiovascular outcomes in hypertension: Angiotensin-converting enzyme inhibitors and angiotensin receptor blockersExpert Opinion on Emerging Drugs.  10:729-745. 2005
2005 Estrogen treatment abrogates neointima formation in human C-reactive protein transgenic mice 2005
2005 Body build and risk of cardiovascular events in hypertension and left ventricular hypertrophy: The LIFE (Losartan Intervention for Endpoint reduction in hypertension) studyCirculation.  111:1924-1931. 2005
2005 Pulse pressure and effects of losartan or atenolol in patients with hypertension and left ventricular hypertrophyHypertension.  45:580-585. 2005
2005 Fixed-dose combinations in the management of hypertension: Defining the place of angiotensin receptor antagonists and hydrochlorothiazideAmerican Journal of Cardiovascular Drugs.  5:17-22. 2005
2005 Conflicting and confusing data from the hypertension treatment trials: whom and what should you believe?Journal of Clinical Hypertension.  7:403-408. 2005
2005 Ethnicity and blood pressure.Journal of Clinical Hypertension.  7:357-364. 2005
2005 Gender and blood pressure.Journal of Clinical Hypertension.  7:300-309. 2005
2005 New-onset diabetes in treated hypertensive patients--is it clinically significant? Roundtable discussion.Journal of Clinical Hypertension.  7:90-95. 2005
2005 Reduction in albuminuria translates to reduction in cardiovascular events in hypertensive patients: Losartan intervention for endpoint reduction in hypertension studyHypertension.  45:198-202. 2005
2005 Role of angiotensin receptor blockers as monotherapy in reaching blood pressure goalsAmerican Journal of Hypertension.  18:287-294. 2005
2005 Stroke reduction in hypertensive adults with cardiac hypertrophy randomized to losartan versus atenolol: The Losartan Intervention for Endpoint reduction in hypertension studyHypertension.  45:46-52. 2005
2005 The effects of losartan compared to atenolol on stroke in patients with isolated systolic hypertension and left ventricular hypertrophy. The LIFE study.Journal of Clinical Hypertension.  7:152-158. 2005
2004 Losartan benefits over atenolol in non-smoking hypertensive patients with left ventricular hypertrophy: The LIFE study 2004
2004 Atrial natriuretic peptide dose-dependently inhibits pressure overload-induced cardiac remodelingHypertension.  44:746-750. 2004
2004 Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells 2004
2004 Estrogen modulates inflammatory mediator expression and neutrophil chemotaxis in injured arteriesCirculation.  110:1664-1669. 2004
2004 Hypertensive therapy: Part ICirculation.  109:2953-2958. 2004
2004 Evidence-based guidelines for cardiovascular disease prevention in women. American Heart Association scientific statement. 2004
2004 Summary of the American Heart Association's evidence-based guidelines for cardiovascular disease prevention in women. 2004
2004 Volume overload results in exaggerated cardiac hypertrophy in the atrial natriuretic peptide knockout mouseCardiovascular Research.  61:771-779. 2004
2004 Evidence-Based Guidelines for Cardiovascular Disease Prevention in WomenCirculation.  109:672-693. 2004
2004 Estradiol and Progestins Differentially Modulate Leukocyte Infiltration after Vascular InjuryCirculation.  109:234-241. 2004
2004 Advanced glycation end-product cross-link breakers: A novel approach to cardiovascular pathologies related to the aging processAmerican Journal of Hypertension.  17:S23-S30. 2004
2004 Essential hypertension in women 2004
2004 Hypertensive therapy: Part II.Circulation.  109:3081-3088. 2004
2004 Interview with Suzanne Oparil, MD. Interview by Marvin Moser, MD.Journal of Clinical Hypertension.  6:509-512. 2004
2004 Roundtable discussion: blood pressure goal attainment: meeting the challenge of the JNC 7's blood pressure goals and the role of renin-angiotensin-aldosterone system blockade.Journal of Clinical Hypertension.  6:699-705. 2004
2003 Albuminuria and Cardiovascular Risk in Hypertensive Patients with Left Ventricular Hypertrophy: The LIFE StudyAnnals of Internal Medicine.  139. 2003
2003 Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood PressureHypertension.  42:1206-1252. 2003
2003 Pathogenesis of HypertensionAnnals of Internal Medicine.  139:761-776. 2003
2003 Hormone replacement therapy and inflammation: Interactions in cardiovascular diseaseHypertension.  42:657-663. 2003
2003 Effects of Losartan or Atenolol in Hypertensive Patients without Clinically Evident Vascular Disease: A Substudy of the LIFE Randomized TrialAnnals of Internal Medicine.  139. 2003
2003 Fibroblast growth factor mediates hypoxia-induced endothelin-A receptor expression in lung artery smooth muscle cells 2003
2003 Effects of pressure overload on extracellular matrix expression in the heart of the atrial natriuretic peptide-null mouseHypertension.  42:88-95. 2003
2003 The seventh report of the joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. The JNC 7 reportEvidence Based Eye Care.  4:179-181. 2003
2003 The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: The JNC 7 Report 2003
2003 Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT): Practical implicationsHypertension.  41:1006-1009. 2003
2003 Pressure-independent enhancement of cardiac hypertrophy in atrial natriuretic peptide-deficient miceClinical and Experimental Pharmacology and Physiology.  30:343-349. 2003
2003 α2A-adrenergic receptors mediate sympathoinhibitory responses to atrial natriuretic peptide in the mouse anterior hypothalamic nucleusHypertension.  41:571-575. 2003
2003 Secondary prevention of coronary heart disease in women: A call to actionAnnals of Internal Medicine.  138:150-151. 2003
2003 Long-Term Safety and Efficacy of the Selective Aldosterone Blocker Eplerenone in Patients with Essential Hypertension 2003
2003 The neointimal response ot endovascular injury is increased in obese Zucker rats 2003
2002 Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT) 2002
2002 Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT-LLT) 2002
2002 Effects of losartan on cardiovascular morbidity and mortality in patients with isolated systolic hypertension and left ventricular hypertrophy: A Losartan Intervention For Endpoint reduction (LIFE) substudy 2002
2002 Fibroblast growth factor receptor-1 signaling induces osteopontin expression and vascular smooth muscle cell-dependent adventitial fibroblast migration in vitroCirculation.  106:854-859. 2002
2002 Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene. 2002
2002 Hormone replacement therapy and hypertensionCurrent Opinion in Nephrology and Hypertension.  11:229-235. 2002
2002 Blood pressure and NaCl-sensitive hypertension are influenced by angiotensin-converting enzyme gene expression in transgenic miceHypertension.  39:214-218. 2002
2002 Sex hormones and hypertensionCardiovascular Research.  53:688-708. 2002
2002 Blood pressure and NaCl-sensitive hypertension are influenced by angiotensin-converting enzyme gene expression in transgenic mice.Hypertension.  39:214-218. 2002
2002 Dietary salt supplementation selectively downregulates NPR-C receptor expression in kidney independently of ANP. 2002
2002 Are there meaningful differences between antihypertensive agents?Cardiology in Review.  19:1-5. 2002
2002 Are there meaningful differences in blood pressure control with current antihypertensive agents?American Journal of Hypertension.  15:14S-21S. 2002
2002 Dietary salt supplementation selectively downregulates NPR-C receptor expression in kidney independently of ANP 2002
2002 Differential ANG II generation in plasma and tissue of mice with decreased expression of the ACE gene 2002
2002 Do angiotensin receptor antagonists have benefits beyond blood pressure lowering?Current Hypertension Reports.  4:219-220. 2002
2002 Interview: Suzanne Oparil, MDCardiology in Review.  19:5-6. 2002
2001 Erratum: Comparative efficacy of olmesartan, losartan, valsartan and irbesartan in the control of essential hypertension (Journal of Clinical Hypertension (2001) vol. 3(5) (283-291, 318))Journal of Clinical Hypertension.  3:395. 2001
2001 Estrogen depletion induces NaCl-sensitive hypertension in female spontaneously hypertensive rats. 2001
2001 Estrogen-induced vasoprotection is independent of inducible nitric oxide synthase expression: Evidence from the mouse carotid artery ligation modelCirculation.  104:2740-2745. 2001
2001 Efficacy of perindopril in the treatment of systemic hypertension.American Journal of Cardiology.  88:3i-12i. 2001
2001 Efficacy of perindopril in the treatment of systemic hypertensionAmerican Journal of Cardiology.  88:3-12. 2001
2001 The American journal of cardiology: IntroductionAmerican Journal of Cardiology.  88. 2001
2001 Tyrosine kinase receptor activation inhibits NPR-C in lung arterial smooth muscle cells. 2001
2001 Cardiovascular effects of estrogen.American Journal of Hypertension.  14:186S-193S. 2001
2001 Efficacy and safety of losartan/hydrochlorothiazide in patients with severe hypertensionAmerican Journal of Cardiology.  87:721-726. 2001
2001 Genetic variation in angiotensin-converting enzyme does not prevent development of cardiac hypertrophy or upregulation of angiotensin II in response to aortocaval fistulaCirculation.  103:1012-1016. 2001
2001 Hormone replacement therapy and stroke: Are the results surprising?Circulation.  103:620-622. 2001
2001 Comparative efficacy of olmesartan, losartan, valsartan, and irbesartan in the control of essential hypertensionJournal of Clinical Hypertension.  3. 2001
2001 Effects of ACE inhibitors, calcium antagonists, and other blood pressure-lowering drugsCurrent Hypertension Reports.  3:227-228. 2001
2001 Estrogen depletion induces NaCl-sensitive hypertension in female spontaneously hypertensive rats 2001
2001 Health outcomes associated with calcium antagonistsCurrent Hypertension Reports.  3:228-229. 2001
2001 Hypertension. Introduction.American Journal of Cardiology.  88. 2001
2001 Primary aldosteronism: A practical approach to diagnosis and treatmentJournal of Clinical Hypertension.  3:189-195. 2001
2001 Treating hypertension in the elderly - Whom to treat, when, and with what?Journal of Clinical Hypertension.  3:103-109. 2001
2001 Tyrosine kinase receptor activation inhibits NPR-C in lung arterial smooth muscle cells 2001
2000 Endothelin and pulmonary hypertensionJournal of Cardiovascular Pharmacology.  35. 2000
2000 Comparison of efficacy and side effects of combination therapy of angiotensin-converting enzyme inhibitor (Benazepril) with calcium antagonist (Either Nifedipine or Amlodipine) versus high-dose calcium antagonist monotherapy for systemic hypertensionAmerican Journal of Cardiology.  86:1182-1187. 2000
2000 Factors affecting blood pressure responses to diet: The vanguard studyAmerican Journal of Hypertension.  13:956-965. 2000
2000 Lowering of blood pressure and predictors of response in patients with left ventricular hypertrophy: The life studyAmerican Journal of Hypertension.  13:899-906. 2000
2000 Lowering of blood pressure and predictors of response in patients with left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint.American Journal of Hypertension.  13:899-906. 2000
2000 A randomized trial of improved weight loss with a prepared meal plan in overweight and obese patients impact on cardiovascular risk reductionArchives of Internal Medicine.  160:2150-2158. 2000
2000 Estrogen attenuates integrin-β3-dependent adventitial fibroblast migration after inhibition of osteopontin production in vascular smooth muscle cellsCirculation.  101:2949-2955. 2000
2000 Fenoldopam, a dopamine agonist, for hypertensive emergency: a multicenter randomized trial. Fenoldopam Study Group.Academic Emergency Medicine.  7:653-662. 2000
2000 Estrogen-induced vasoprotection is estrogen receptor dependent: Evidence from the balloon-injured rat carotid artery modelCirculation.  101:2342-2344. 2000
2000 Effects of short-term estrogen treatment on the neointimal response to balloon injury of rat carotid arteryAmerican Journal of Cardiology.  85:1276-1279. 2000
2000 Direct in vivo evidence demonstrating neointimal migration of adventitial fibroblasts after balloon injury of rat carotid arteriesCirculation.  101:1362-1365. 2000
2000 Essential hypertension part II: TreatmentCirculation.  101:446-453. 2000
2000 Essential hypertension. Part I: Definition and etiologyCirculation.  101:329-335. 2000
2000 Antihypertensive drug therapy in the third millennium: Are there benefits beyond blood pressure?Current Hypertension Reports.  2:291-294. 2000
2000 Calcium antagonists in cardiovascular disease: Clinical evidence from morbidity and mortality trialsDrugs.  59:25-37. 2000
2000 Endothelial dysfunction in the pulmonary vascular bedAmerican Journal of the Medical Sciences.  320:223-232. 2000
2000 Endothelin and pulmonary hypertension.Journal of Cardiovascular Pharmacology.  35:S49-S53. 2000
2000 Fenoldopam, a dopamine agonist, for hypertensive emergency: A multicenter randomized trialAcademic Emergency Medicine.  7:653-662. 2000
2000 Newly emerging pharmacologic differences in angiotensin II receptor blockersAmerican Journal of Hypertension.  13. 2000
2000 Newly emerging pharmacologic differences in angiotensin II receptor blockers.American Journal of Hypertension.  13:18S-24S. 2000
1999 Bradykinin in the heart: Friend or foe?Circulation.  100:2305-2307. 1999
1999 Estrogen attenuates the adventitial contribution to neointima formation in injured rat carotid arteriesCardiovascular Research.  44:608-614. 1999
1999 Harriet Pearson Dustan.Circulation.  100:2122-2123. 1999
1999 Candesartan cilexetil in combination with low-dose hydrochlorothiazide is effective in severe hypertension.American Journal of Cardiology.  84:35S-41S. 1999
1999 Treating multiple-risk hypertensive populations.American Journal of Hypertension.  12:121S-129S. 1999
1999 Estrogen inhibits vascular smooth muscle cell-dependent adventitial fibroblast migration in vitroCirculation.  100:1639-1645. 1999
1999 Effects of candesartan cilexetil in patients with severe systemic hypertensionAmerican Journal of Cardiology.  84:289-293. 1999
1999 Effects of candesartan cilexetil in patients with severe systemic hypertension. Candesartan Cilexetil Study Investigators.American Journal of Cardiology.  84:289-293. 1999
1999 Fenoldopam: A new parenteral antihypertensive: Consensus roundtable on the management of perioperative hypertension and hypertensive crisesAmerican Journal of Hypertension.  12:653-664. 1999
1999 Evidence for angiotensin-converting enzyme- and chymase-mediated angiotensin II formation in the interstitial fluid space of the dog heart in vivoCirculation.  99:2583-2589. 1999
1999 Guide to Preventive Cardiology for Women.AHA/ACC Scientific Statement Consensus panel statement.Circulation.  99:2480-2484. 1999
1999 Guide to preventive cardiology for womenCirculation.  99:2480-2484. 1999
1999 A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertensionAmerican Journal of Hypertension.  12:414-417. 1999
1999 A comparison of the angiotensin II antagonists valsartan and losartan in the treatment of essential hypertension.American Journal of Hypertension.  12:414-417. 1999
1999 Journal of Cardiovascular Pharmacology: IntroductionJournal of Cardiovascular Pharmacology.  33. 1999
1999 Long-term morbidity and mortality trials with amlodipineJournal of Cardiovascular Pharmacology.  33. 1999
1999 Management of the hypertensive patient with coronary artery disease.American Journal of Hypertension.  12:56S-62S. 1999
1999 Multicenter randomized trial of a comprehensive prepared meal program in type 2 diabetesDiabetes Care.  22:191-197. 1999
1999 Arthur C. Corcoran Memorial Lecture. Hormones and vasoprotection.Hypertension.  33:170-176. 1999
1999 Candesartan cilexetil in combination with low-dose hydrochlorothiazide is effective in severe hypertension.American Journal of Cardiology.  84:35-41. 1999
1999 Clinical experience with transdermal clonidine in African-American and Hispanic-American patients with hypertension: Evaluation from a 12-week prospective, open-label clinical trial in community-based clinicsAmerican Journal of Therapeutics.  6:19-24. 1999
1999 Comparison of telmisartan with lisinopril in patients with mild-to- moderate hypertensionAmerican Journal of Therapeutics.  6:161-166. 1999
1999 Eprosartan versus enalapril in hypertensive patients with angiotensin- converting enzyme inhibitor-induced cough 1999
1999 Hypertension in womenJournal of Clinical Endocrinology and Metabolism.  84:1862-1866. 1999
1999 Increased dietary micronutrients decrease serum homocysteine concentrations in patients at high risk of cardiovascular diseaseAmerican Journal of Clinical Nutrition.  70:881-887. 1999
1999 Management of the hypertensive patient with coronary artery diseaseAmerican Journal of Hypertension.  12:56S-62S. 1999
1999 Nontraditional cardiovascular risk factorsAmerican Journal of the Medical Sciences.  317:193-207. 1999
1999 Recent outcome trials of newer antihypertensivesCurrent Hypertension Reports.  1:238-240. 1999
1999 Treating multiple-risk hypertensive populationsAmerican Journal of Hypertension.  12:121-129. 1999
1998 Characteristics of 9194 patients with left ventricular hypertrophy: the LIFE study. Losartan Intervention For Endpoint Reduction in Hypertension.Hypertension.  32:989-997. 1998
1998 The evolving role of angiotensin-II receptor blockers in cardiovascular risk reduction. Case study.American Journal of Hypertension.  11:192S-194S. 1998
1998 Effects of Candesartan cilexetil in patients with systemic hypertensionAmerican Journal of Cardiology.  82:961-965. 1998
1998 Effects of candesartan cilexetil in patients with systemic hypertension. Candesartan Cilexetil Study Investigators.American Journal of Cardiology.  82:961-965. 1998
1998 Garlic prevents hypoxic pulmonary hypertension in rats.American Journal of Physiology.  275:L283-L287. 1998
1998 Pathophysiology of sudden coronary death in women: Implications for preventionCirculation.  97:2103-2105. 1998
1998 An elective-titration study of the comparative effectiveness of two angiotensin II-receptor blockers, irbesartan and losartan. Irbesartan/Losartan Study Investigators. 1998
1998 Antihypertensive treatment in postmenopausal women: Results from a prospective, randomized, double-blind, controlled study comparing an ACE inhibitor (Moexipril) with a diuretic (Hydrochlorothiazide) 1998
1998 Mibefradil, a T-channel-selective calcium antagonist: clinical trials in hypertension.American Journal of Hypertension.  11:88S-94S. 1998
1998 Managing the patient with hard-to-control hypertensionAmerican Family Physician.  57:1007-1014. 1998
1998 An elective-titration study of the comparative effectiveness of two angiotensin II-receptor blockers, irbesartan and losartan 1998
1998 Case studyAmerican Journal of Hypertension.  11. 1998
1998 Characteristics of 9194 patients with left ventricular hypertrophy: The LIFE studyHypertension.  32:989-997. 1998
1998 Comprehensive nutrition plan improves cardiovascular risk factors in essential hypertensionAmerican Journal of Hypertension.  11:31-40. 1998
1998 Comprehensive nutrition plan improves cardiovascular risk factors in essential hypertension.American Journal of Hypertension.  11:31-40. 1998
1998 Dose-responsive antihypertensive efficacy of valsartan, a new angiotensin II-receptor blocker 1998
1998 Garlic prevents hypoxic pulmonary hypertension in rats 1998
1998 Healthier diets improve quality of life while reducing cardiovascular disease risk factorsDisease Management and Clinical Outcomes.  1:106-113. 1998
1998 Mibefradil, a T-channel-selective calcium antagonist: Clinical trials in hypertensionAmerican Journal of Hypertension.  11:88S-94S. 1998
1998 The sexual dimorphism of high blood pressureCardiology in Review.  6:356-363. 1998
1997 No role for NO in estrogen-mediated vasoprotection?Circulation.  96:2769-2771. 1997
1997 High blood pressure in women 1997
1997 Angiotensin II formation from ACE and chymase in human and animal hearts: methods and species considerations.American Journal of Physiology.  273:H1769-H1774. 1997
1997 Hypoxia stimulates human preproendothelin-1 promoter activity in transgenic mice.American Journal of Physiology.  273:L848-L855. 1997
1997 Volume-overload cardiac hypertrophy is unaffected by ACE inhibitor treatment in dogs 1997
1997 A 42-year-old man with hypertension 1997
1997 Estrogen restores endothelial cell function in an experimental model of vascular injuryCirculation.  96:1624-1630. 1997
1997 Antihypertensive effects of mibefradil in the treatment of mild-to- moderate systemic hypertensionAmerican Journal of Cardiology.  80. 1997
1997 Antihypertensive effects of mibefradil in the treatment of mild-to-moderate systemic hypertension.American Journal of Cardiology.  80:12C-19C. 1997
1997 Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertensionAmerican Journal of Hypertension.  10:735-742. 1997
1997 Volume-overload cardiac hypertrophy is unaffected by ACE inhibitor treatment in dogs.American Journal of Physiology.  273:H961-H970. 1997
1997 Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene function.Hypertension.  30:128-133. 1997
1997 Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension.American Journal of Hypertension.  10:735-742. 1997
1997 The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. The LIFE Study Group.American Journal of Hypertension.  10:705-713. 1997
1997 The orally active nonpeptide endothelin A-receptor antagonist A-127722 prevents and reverses hypoxia-induced pulmonary hypertension and pulmonary vascular remodeling in Sprague-Dawley ratsJournal of Cardiovascular Pharmacology.  29:713-725. 1997
1997 ALLHAT and calcium channel blockers [3]American Journal of Hypertension.  10:142-143. 1997
1997 ALLHAT and calcium channel blockers. ALLHAT Research Group.American Journal of Hypertension.  10:142-143. 1997
1997 Angiotensin II formation from ACE and chymase in human and animal hearts: Methods and species considerations 1997
1997 Blood pressure and metabolic responses to moderate sodium restriction in isradipine-treated hypertensive patientsAmerican Journal of Hypertension.  10:68-76. 1997
1997 Blood pressures and cardiovascular homeostasis in mice having reduced or absent angiotensin-converting enzyme gene functionHypertension.  30:128-133. 1997
1997 Dietary compliance and cardiovascular risk reduction with a prepared meal plan compared with a self-selected dietAmerican Journal of Clinical Nutrition.  66:373-385. 1997
1997 Erratum: Dose-response characteristics of mibefradil, a novel calcium antagonist, in the treatment of essential hypertension (American Journal of Hypertension (July 1997) 10 (735-742))American Journal of Hypertension.  10:1081. 1997
1997 Fenoldopam: A novel, peripherally acting dopamine-1 agonist for parenteral treatment of hypertensionDrugs of Today.  33:729-738. 1997
1997 Hypoxia stimulates human preproendothelin-1 promoter activity in transgenic mice 1997
1997 Nutritional management of cardiovascular risk factors: A randomized clinical trialArchives of Internal Medicine.  157:169-177. 1997
1997 Sexually dimorphic response of the balloon-injured rat carotid artery to hormone treatmentCirculation.  95:1301-1307. 1997
1997 The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study rationale, design, and methodsAmerican Journal of Hypertension.  10:705-713. 1997
1997 The expanding role of calcium antagonists in cardiovascular disease 1997
1997 Tolerability profile of tasosartan, a long-acting angiotensin II AT1 receptor blocker, in the treatment of patients with essential hypertension 1997
1997 Volume-overload cardiac hypertrophy is unaffected by ACE inhibitor treatment in dogs 1997
1996 White Coat Hypertension???Fact or Fancy?American Journal of the Medical Sciences.  312:219-220. 1996
1996 Purification and assay methods for angiotensin-converting enzyme 1996
1996 Preventing heart attack and death in patients with coronary disease. Endorsed by the board of trustees of the American College of Cardiology.Cardio-vascular nursing.  32:26-28. 1996
1996 Antihypertensive therapy in the era of evidence based medical practice: What to do until the facts are inCurrent Opinion in Nephrology and Hypertension.  5:159-161. 1996
1996 Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). ALLHAT Research Group.American Journal of Hypertension.  9:342-360. 1996
1996 Acute saline infusion decreases norepinephrine release in the anterior hypothalamic area.Hypertension.  27:578-583. 1996
1996 Estrogen reduces myointimal proliferation after balloon injury of rat carotid arteryCirculation.  93:577-584. 1996
1996 Anterior hypothalamic norepinephrine, atrial natriuretic peptide, and hypertensionFrontiers in Neuroendocrinology.  17:212-246. 1996
1996 Antihypertensive therapy and atherosclerosis in coronary heart diseaseCardiovascular Risk Factors.  6:222-232. 1996
1996 Atrial natriuretic peptide blunts arterial baroreflex in spontaneously hypertensive ratsHypertension.  27:297-302. 1996
1996 Cardiac renin angiotensin system in hypertrophy and the progression to heart failureHeart Failure Reviews.  1:63-72. 1996
1996 Classic papers symposium of the southern clinical research meetings: White coat hypertension - Fact or fancy?American Journal of the Medical Sciences.  312:219-220. 1996
1996 Efficacy, tolerability, and effects on quality of life of losartan, alone or with hydrochlorothiazide, versus amlodipine, alone or with hydrochlorothiazide, in patients with essential hypertension 1996
1996 Hypertension: Initial evaluationACC Current Journal Review.  5:60-62. 1996
1996 Improved quality of life in patients with generalized cardiovascular metabolic disease on a prepared dietAmerican Journal of Clinical Nutrition.  64:935-943. 1996
1996 Medroxyprogesterone attenuates estrogen-mediated inhibition of neointima formation after balloon injury of the rat carotid arteryCirculation.  94:2221-2227. 1996
1996 Rationale and design for the antihypertensive and lipid lowering treatment to prevent heart attack trial (ALLHAT)American Journal of Hypertension.  9:342-360. 1996
1996 Salt intake and plasma atrial natriuretic peptide and nitric oxide in hypertensionHypertension.  28:335-340. 1996
1996 The efficacy and safety of valsartan compared with placebo in the treatment of patients with essential hypertension 1996
1995 Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation.American Journal of Physiology.  269:H2065-H2073. 1995
1995 ETA-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat.American Journal of Physiology.  269:L690-L697. 1995
1995 Sensitive method for quantitation of angiotensin-converting enzyme (ACE) activity in tissueBiochemical Pharmacology.  50:1445-1450. 1995
1995 Hypertension in postmenopausal women: Pathophysiology and managementCurrent Opinion in Nephrology and Hypertension.  4:438-442. 1995
1995 Calcium antagonists: Antihypertensive and vascular considerations 1995
1995 Acute hypertension increases norepinephrine release in the anterior hypothalamic area.Hypertension.  25:828-833. 1995
1995 Cardiovascular health at the crossroads: outlook for the 21st century. Presented at the 67th Scientific Sessions of the American Heart Association November 4, 1994 Dallas, Texas.Circulation.  91:1304-1310. 1995
1995 Selective downregulation of ANP-clearance-receptor gene expression in lung of rats adapted to hypoxia.American Journal of Physiology.  268:L328-L335. 1995
1995 ET(A)-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat 1995
1995 Effect of amlodipine on left ventricular mass in the amlodipine cardiovascular community trialJournal of Cardiovascular Pharmacology.  26:471-476. 1995
1995 Endothelin-A receptor antagonist prevents acute hypoxia-induced pulmonary hypertension in the rat 1995
1995 Endothelin-A receptor antagonist prevents acute hypoxia-induced pulmonary hypertension in the rat.American Journal of Physiology.  268:L95-100. 1995
1995 Endothelin-receptor antagonist bosentan prevents and reverses hypoxic pulmonary hypertension in rats 1995
1995 Fighting the NIH funding crisisCirculation.  91:2502. 1995
1995 Gender and dietary NaCl in spontaneously hypertensive and Wistar-Kyoto ratsHypertension.  26:285-289. 1995
1995 Increased ACE and chymase-like activity in cardiac tissue of dogs with chronic mitral regurgitation 1995
1995 Preventing heart attack and death in patients with coronary diseaseCirculation.  92:2-4. 1995
1995 Racial differences in the pathogenesis of hypertensionAmerican Journal of the Medical Sciences.  310. 1995
1995 SSCI founders medal recipient's addressAmerican Journal of the Medical Sciences.  310:4-5. 1995
1995 Selective downregulation of ANP-clearance-receptor gene expression in lung of rats adapted to hypoxia 1995
1994 Increased endothelin receptor gene expression in hypoxic rat lung.American Journal of Physiology.  266:L553-L560. 1994
1994 Antihypertensive therapy in the context of total cardiovascular risk: the rational basis for therapeutic recommendations.Current Opinion in Nephrology and Hypertension.  3:195-199. 1994
1994 Diurnal blood pressure variation and dietary salt in spontaneously hypertensive ratsHypertension.  24:1-7. 1994
1994 Enhanced endothelin-1 and endothelin receptor gene expression in chronic hypoxia 1994
1994 Increased endothelin receptor gene expression in hypoxic rat lung 1994
1994 Increased endothelin receptor gene expression in hypoxic rat lung 1994
1994 Mithramycin inhibits myointimal proliferation after balloon injury of the rat carotid artery in vivoCirculation.  90:2468-2473. 1994
1994 Role of anterior hypothalamic angiotensin II in the pathogenesis of salt sensitive hypertension in the spontaneously hypertensive ratAmerican Journal of the Medical Sciences.  307. 1994
1994 Sodium-proton (Na+/H+) exchange inhibition increases blood pressure in spontaneously hypertensive ratAmerican Journal of the Medical Sciences.  308:145-151. 1994
1993 Report of the task force on children and youth. American Heart Association.Circulation.  88:2479-2486. 1993
1993 Simplified method for quantitation of angiotensin peptides in tissueJournal of Chromatography - Biomedical Applications.  614:19-25. 1993
1993 Coarctation induces alterations in basement membranes in the cardiovascular systemHypertension.  22:743-753. 1993
1993 Excitatory sympathetic reflex in NaCl-sensitive spontaneously hypertensive ratsHypertension.  22:285-291. 1993
1993 Nitric oxide mediates immune dysfunction in the spontaneously hypertensive ratHypertension.  21:185-194. 1993
1993 Normotensive blacks have heightened sympathetic response to cold pressor testHypertension.  22:801-805. 1993
1993 Presentation of the Southern Society for Clinical Investigation Founder's Medal to Dr. James A. Pittman, Jr.American Journal of the Medical Sciences.  306:1-3. 1993
1993 Report of the task force on children and youthCirculation.  88:2479-2485. 1993
1992 Normobaric hypoxia stimulates endothelin-1 gene expression in the rat.American Journal of Physiology.  263:R1260-R1264. 1992
1992 Converting-enzyme inhibitors increase converting-enzyme mRNA and activity in endothelial cells.American Journal of Physiology.  263:C743-C749. 1992
1992 Preparative isolation of angiotensin-converting enzyme from human lungJournal of Chromatography - Biomedical Applications.  579:63-71. 1992
1992 Isolation of two distinct type I angiotensin II receptor genesBiochemical and Biophysical Research Communications.  184:1067-1073. 1992
1992 Effects of acute and chronic blockade of neutral endopeptidase with Sch 34826 on NaCl-sensitive hypertension in spontaneously hypertensive rats.American Journal of Hypertension.  5:210-218. 1992
1992 Androgen-dependent angiotensinogen and renin messenger RNA expression in hypertensive ratsHypertension.  19:456-463. 1992
1992 Atrial natriuretic peptide modulates baroreceptor reflex in spontaneously hypertensive ratHypertension.  20:374-379. 1992
1992 Blocking hypothalamic AT1 receptors lowers blood pressure in salt- sensitive ratsHypertension.  20:755-762. 1992
1992 Cicletanine blunts the pulmonary pressor response to acute hypoxia in ratsAmerican Journal of the Medical Sciences.  304:14-19. 1992
1992 Converting-enzyme inhibitors increase converting-enzyme mRNA and activity in endothelial cellsAmerican Journal of Physiology.  263. 1992
1992 Depressor effect of blocking angiotensin subtype 1 receptors in anterior hypothalamusHypertension.  19:475-481. 1992
1992 Effects of acute and chronic blockade of neutral endopeptidase with sch 34826 on nacl-sensitive hypertension in spontaneously hypertensive ratsAmerican Journal of Hypertension.  5:210-218. 1992
1992 Ganglion atrial natriuretic peptide in nacl sensitive spontaneously hypertensive ratsAmerican Journal of Hypertension.  5:806-810. 1992
1992 Neuronal control of the kidney: Contribution to hypertensionCanadian Journal of Physiology and Pharmacology.  70:759-770. 1992
1992 Normobaric hypoxia stimulates endothelin-1 gene expression in the ratAmerican Journal of Physiology.  263. 1992
1992 Preparative isolation of angiotensin-converting enzyme from human lungJournal of Chromatography - Biomedical Applications.  579:63-71. 1992
1992 Pressor effect of blocking atrial natriuretic peptide in nucleus tractus solitariiHypertension.  19:198-205. 1992
1992 Quantitation of hypothalamic atrial natriuretic peptide messenger RNA in hypertensive ratsHypertension.  19:296-300. 1992
1992 Salt supplementation does not alter the pressor effect of blocking atrial natriuretic peptide in nucleus tractus solitariiHypertension.  20:242-246. 1992
1992 Spontaneously hypertensive rat: Lymphoid depression is age dependent and mediated via a mononuclear cell subpopulationAmerican Journal of Physiology.  262. 1992
1992 Spontaneously hypertensive rat: lymphoid depression is age dependent and mediated via a mononuclear cell subpopulation.American Journal of Physiology.  262:R1-R7. 1992
1991 Decreased norepinephrine release in anterior hypothalamus of NaCl-sensitive spontaneously hypertensive rats during high NaCl intakeBrain Research.  565:135-141. 1991
1991 Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats via sympatholytic and renal effectsAmerican Journal of Clinical Nutrition.  54. 1991
1991 Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats via sympatholytic and renal effects.American Journal of Clinical Nutrition.  54:227S-236S. 1991
1991 The calcium antagonists in the 1990s. An overview.American Journal of Hypertension.  4:396S-405S. 1991
1991 Altered stores of atrial natriuretic peptide in specific brain nuclei of NaCl-sensitive spontaneously hypertensive rats.American Journal of Hypertension.  4:449-455. 1991
1991 Altered stores of atrial natriuretic peptide in specific brain nuclei of nacl-sensitive spontaneously hypertensive ratsAmerican Journal of Hypertension.  4:449-455. 1991
1991 Antihypertensive effect of cicletanine is exaggerated in NaCl-sensitive hypertensionAmerican Journal of the Medical Sciences.  301:383-389. 1991
1991 Atrial natriuretic peptide in acute hypoxia-induced pulmonary hypertension in rats 1991
1991 High NaCl diet enhances arterial baroreceptor reflex in NaCl-sensitive spontaneously hypertensive ratsHypertension.  17:363-368. 1991
1991 Intrahypothalamic clonidine infusion prevents NaCl-sensitive hypertensionHypertension.  18:224-229. 1991
1991 The calcium antagonists in the 1990s an overviewAmerican Journal of Hypertension.  4:396S-405S. 1991
1990 In Reply 1990
1990 Dietary Ca2+ prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanism.American Journal of Hypertension.  3:179S-188S. 1990
1990 High-performance liquid chromatographic determination of amiloride and its analogues in rat plasma.J Chromatogr.  529:201-209. 1990
1990 An Assessment of Diltiazem and Hydrochlorothiazide in Hypertension 1990
1990 An Assessment of Diltiazem and Hydrochlorothiazide in Hypertension: Application of Factorial Trial Design to a Multicenter Clinical Trial of Combination Therapy 1990
1990 Vascular effects of kinins in trout and bradykinin metabolism by perfused gill.American Journal of Physiology.  258:R515-R522. 1990
1990 Atrial natriuretic factor prevents NaCl-sensitive hypertension in spontaneously hypertensive ratsHypertension.  15:170-176. 1990
1990 Atrial natriuretic peptide clearance receptor agonist lowers pulmonary pressure in hypoxic rats 1990
1990 Changes in cerebrospinal fluid Na+ concentration do not underlie hypertensive responses to dietary NaCl in spontaneously hypertensive ratsBrain Research.  506:149-152. 1990
1990 Dietary ca2+prevents NaCl-sensitive hypertension in spontaneously hypertensive rats by a sympatholytic mechanismAmerican Journal of Hypertension.  3:179S-188S. 1990
1990 High-performance liquid chromatographic determination of amiloride and its analogues in rat plasmaJournal of Chromatography - Biomedical Applications.  529:201-209. 1990
1990 Interleukin-2 does not attenuate hypertension in spontaneously hypertensive ratsHypertension.  16:468-471. 1990
1990 NaCl does not affect hypothalamic noradrenergic input in deoxycorticosterone acetate/NaCl and dahl salt-sensitive ratsHypertension.  16:55-62. 1990
1990 Noninvasive Assessment of Renal Artery Stenosis by Combined Conventional and Color Doppler Ultrasound 1990
1990 Vascular effects of kinins in trout and bradykinin metabolism by perfused gillAmerican Journal of Physiology.  258. 1990
1989 Central mechanisms of hypertension.American Journal of Hypertension.  2:477-485. 1989
1989 Dietary NaCl loading enhances antihypertensive effect of guanabenz in spontaneously hypertensive rats.American Journal of Hypertension.  2:435-439. 1989
1989 Hypoxia stimulates endothelial cell angiotensin-converting enzyme antigen synthesis.American Journal of Physiology.  256:C1231-C1238. 1989
1989 Atrial natriuretic factor in NaCl-sensitive and NaCl-resistant spontaneously hypertensive ratsHypertension.  14:404-412. 1989
1989 Atrial natriuretic peptide lowers pulmonary arterial pressure in patients with high altitude diseaseAmerican Journal of the Medical Sciences.  298:397-401. 1989
1989 Central mechanisms of hypertensionAmerican Journal of Hypertension.  2:477-485. 1989
1989 Dietary Ca2+ supplementation prevents the exaggerated responsiveness of anterior hypothalamic α2-adrenoceptors in NaCl-loaded spontaneously hypertensive ratsJournal of Cardiovascular Pharmacology.  13:162-167. 1989
1989 Hemodynamic effects of arginine vasopressin in rats adapted to chronic hypoxia 1989
1989 HypertensionDisease-A-Month.  35:138-232. 1989
1989 Hypoxia stimulates endothelial cell angiotensin-converting enzyme antigen synthesisAmerican Journal of Physiology.  256. 1989
1989 Impaired reflex response to volume expansion in NaCl-sensitive spontaneously hypertensive ratsHypertension.  14:518-524. 1989
1989 Purification of angiotensin-converting enzyme by gel high-performance liquid chromatography 1989
1989 Renal nerve contribution to NaCl-exacerbated hypertension in spontaneously hypertensive ratsHypertension.  14:184-190. 1989
1989 Vasopressin lowers pulmonary artery pressure in hypoxic rats by releasing atrial natriuretic peptideAmerican Journal of the Medical Sciences.  298:227-236. 1989
1988 Enhanced cold pressor response in spontaneously hypertensive rats on high-NaCl dietAmerican Journal of Physiology.  255. 1988
1988 Enhanced cold pressor response in spontaneously hypertensive rats on high-NaCl diet.American Journal of Physiology.  255:H1018-H1023. 1988
1988 Treating the older hypertensive patient-an overviewAmerican Journal of Medicine.  85:1. 1988
1988 Effect of steric exclusion on the separation of proteins by hydrophilic size-exclusion chromatography.J Chromatogr.  445:29-36. 1988
1988 Exaggerated depressor response to 6-iodoamiloride in NaCl-sensitive spontaneously hypertensive rats.American Journal of the Medical Sciences.  296:78-83. 1988
1988 High NaCl diet increases anterior hypothalamic α2-adrenoceptors in SHRBrain Research.  451:77-84. 1988
1988 Impaired release of atrial natriuretic factor in NaCl-loaded spontaneously hypertensive rats.Hypertension.  11:739-744. 1988
1988 Captopril and the response to stress in the spontaneously hypertensive rat.Hypertension.  11:I144-I147. 1988
1988 Altered angiotensin-converting enzyme in lung and extrapulmonary tissues of hypoxia-adapted rats 1988
1988 Atrial natriuretic peptide lowers pulmonary arterial pressure in hypoxia-adapted rats 1988
1988 Captopril and the response to stress in the spontaneously hypertensive ratHypertension.  11:I-144-I-147. 1988
1988 Effect of steric exclusion on the separation of proteins by hydrophilic size-exclusion chromatography 1988
1988 Genetic basis of NaCl-sensitive hypertensionJournal of Cardiovascular Pharmacology.  12:S56-S69. 1988
1988 High NaCl diet reduces hypothalamic norepinephrine turnover in hypertensive ratsHypertension.  11:55-62. 1988
1988 Hypoxia-induced oxygen tolerance: Maintenance of endothelial metabolic functionExperimental Lung Research.  14:887-896. 1988
1988 Impaired release of atrial natriuretic factor in NaCl-loaded spontaneously hypertensive ratsHypertension.  11:739-744. 1988
1988 Perioperative red blood cell transfusion 1988
1988 Rapid communication: Exaggerated depressor response to 6-iodoamiloride in NaCl-sensitive spontaneously hypertensive ratsAmerican Journal of the Medical Sciences.  296:78-83. 1988
1988 The neural basis of salt sensitivity in the rat: Altered hypothalamic functionAmerican Journal of the Medical Sciences.  295:360-369. 1988
1987 Altered responsiveness of regional brain dopamine and DOPAC levels to systemic administration of quinpirole, a dopamine D2 agonist, in DOCA/NaCl-hypertensive ratsBrain Research.  413:15-22. 1987
1987 De novo intrarenal formation of angiotensin II during control and enhanced renin secretion.American Journal of Physiology.  252:F1118-F1123. 1987
1987 Exacerbation of hypertension by high chloride, moderate sodium diet in the salt-sensitive spontaneously hypertensive rat.Hypertension.  9:III171-III175. 1987
1987 Sympathetic function in spontaneously hypertensive rats after chronic administration of captopril.American Journal of Physiology.  252:H796-H806. 1987
1987 Two renal alpha 2-adrenergic receptor sites revealed by p-aminoclonidine binding.American Journal of Physiology.  252:F283-F290. 1987
1987 Enhanced response to the inhibitory action of LY171555, a dopamine D2-agonist, on in vivo striatal dopamine release in DOCA/NaCl-hypertensive ratsBrain Research.  400:225-231. 1987
1987 Antihypertensive effect of enalapril in essential hypertension: Role of prostacyclinAmerican Journal of the Medical Sciences.  294:395-402. 1987
1987 Blunted responsiveness of posterior hypothalamic norepinephrine to quinpirole in DOCA/NaCl hypertensive ratsBrain Research Bulletin.  18:563-568. 1987
1987 De novo intrarenal formation of angiotensin II during control and enhanced renin secretionAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  252. 1987
1987 Exacerbation of hypertension by high chloride, moderate sodium diet in the salt-sensitive spontaneously hypertensive ratHypertension.  9:III-171-III-175. 1987
1987 Failure of renal denervation to attenuate hypertension in Dahl NaCl-sensitive ratsCanadian Journal of Physiology and Pharmacology.  65:2428-2432. 1987
1987 Hyperoxia-induced converting enzyme insufficiency in conscious rat: Cardiovascular effectsExperimental Lung Research.  12:37-56. 1987
1987 Hypertension produced by a high sodium diet in the borderline hypertensive rat (BHR)Clinical and experimental hypertension.  A9:1713-1731. 1987
1987 Hypertension produced by a high sodium diet in the borderline hypertensive rat (BHR).Clinical and experimental hypertension.  9:1713-1731. 1987
1987 Hypoxia-induced inhibition of converting enzyme activity: Role in vascular regulation 1987
1987 Proteoglycans and hypertension: III: Aorta proteoglycans in Dahl salt-sensitive hypertensive ratsAmerican Journal of the Medical Sciences.  293:171-176. 1987
1987 Spontaneously hypertensive rats exhibit reduced hypothalamic noradrenergic input after NaCl loadingHypertension.  10:313-320. 1987
1987 Sympathetic function in spontaneously hypertensive rats after chronic administration of captopril 1987
1987 The antihypertensive effect of lisinopril compared to atenolol in patients with mild to moderate hypertensionJournal of Cardiovascular Pharmacology.  9:S43-S47. 1987
1987 The renal afferent nerves in the pathogenesis of hypertensionCanadian Journal of Physiology and Pharmacology.  65:1548-1558. 1987
1987 Two renal α2-adrenergic receptor sites revealed by p-aminoclonidine bindingAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  252. 1987
1987 Yohimbine-induced alterations of monoamine metabolism in the spontaneously hypertensive rat of the okamoto strain (SHR). II. The Central Nervous System (CNS)Brain Research Bulletin.  19:525-534. 1987
1987 Yohimbine-induced alterations of monoamine metabolism in the spontaneously hypertensive rat. I. The peripheral nervous systemBrain Research Bulletin.  19:101-108. 1987
1986 Transport and hydrolysis of glucagon in the proximal nephron.American Journal of Physiology.  251:F460-F467. 1986
1986 Angiotensin extraction by trout tissues in vivo and metabolism by the perfused gill.American Journal of Physiology.  250:R532-R538. 1986
1986 Angiotensin extraction by trout tissues in vivo and metabolism by the perfused gill 1986
1986 Impaired pulmonary conversion of angiotensin I to angiotensin II in rats exposed to chronic hypoxia 1986
1986 Increased vasopressinergic activity following DOCA administration in the ratBrain Research Bulletin.  16:93-98. 1986
1986 Sensory denervation of the kidney attenuates renovascular hypertension in the rat 1986
1986 Sensory denervation of the kidney attenuates renovascular hypertension in the rat.American Journal of Physiology.  250:H82-H86. 1986
1986 Transport and hydrolysis of glucagon in the proximal nephronAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  251. 1986
1985 Enhanced depressor effect of bromocriptine in the DOCA/NaCl hypertensive rat 1985
1985 Hyperresponsiveness of monoaminergic mechanisms in DOCA/NaCl hypertensive rats 1985
1985 Hypertension in a 74-year-old man with hydronephrosis and coronary disease.Hypertension.  7:824-833. 1985
1985 Enhanced depressor effect of bromocriptine in the DOCA/NaCl hypertensive rat.American Journal of Physiology.  249. 1985
1985 Hyperresponsiveness of monoaminergic mechanisms in DOCA/NaCl hypertensive rats.American Journal of Physiology.  249. 1985
1985 Enhanced Depressor Effect of Muscimol in the DOCA/NaCl Hypertensive Rat: Evidence for Altered GABAergic Activity in Brain 1985
1985 Hypertension in a 74-year-old man with hydronephrosis and coronary disease principal discussantHypertension.  7:824-833. 1985
1984 The role of the posterior hypothalamic area in the pathogenesis of hypertension in the spontaneously hypertensive ratBrain Research.  324:51-58. 1984
1984 Myocardial cell hypertrophy or hyperplasiaHypertension.  6. 1984
1984 Renal handling of glucagon and insulin.Contributions to Nephrology.  42:30-37. 1984
1984 Myocardial cell hypertrophy or hyperplasia.Hypertension.  6:III38-III43. 1984
1984 Hormonal and haemodynamic responses to upper abdominal surgery during isoflurane and balanced anaesthesiaCanadian Anaesthetists' Society journal.  31:509-516. 1984
1984 Subcellular sites of insulin hydrolysis in renal proximal tubulesAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  15. 1984
1984 Elevated catecholamines during cardiac surgery: Consequences of reperfusion of the postarrested heartAmerican Journal of Cardiology.  53:722-728. 1984
1984 A randomized comparison of crystalloid and blood-containing cardioplegic solutions in 60 patientsCirculation.  69:973-982. 1984
1984 Comprehensive drug management of hypertensionCardiovascular clinics.  14:73-91. 1984
1984 Myocardial cell hypertrophy or hyperplasiaHypertension.  6:38-43. 1984
1984 Subcellular sites of insulin hydrolysis in renal proximal tubulesAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  15. 1984
1983 Effect of hypoxia on the conversion of angiotensin I to II in cultured porcine pulmonary endothelial cellsBiochemical Pharmacology.  32:1201-1205. 1983
1983 Altered vascular reactivity and baroreflex sensitivity induced by chronic central administration of captopril in the spontaneously hypertensive ratHypertension.  5:689-700. 1983
1983 Attenuation of the development of spontaneous hypertension in rats by chronic central administration of captoprilHypertension.  5:653-662. 1983
1983 Central catecholamine depletion, vasopressin, and blood pressure in the DOCA/NaCl rat 1983
1983 Central catecholamine depletion, vasopressin, and blood pressure in the DOCA/NaCl rat 1983
1983 Enalapril in low-renin essential hypertensionClinical Pharmacology and Therapeutics.  34:297-302. 1983
1983 Intrarenal angiotensin I conversion at normal and reduced renal blood flow in the dogAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  14. 1983
1983 Kidney function and sodium handling in the pregnant spontaneously hypertensive ratHypertension.  5:498-506. 1983
1983 Role of the renal nerves in the maintenance of DOCA-salt hypertension in the rat. Influence on the renal vasculature and sodium excretionHypertension.  5:427-435. 1983
1982 Differences between renal tubular processing of glucagon and insulinAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  11. 1982
1982 Importance of the renal nerves in the pathogenesis of experimental hypertension.Hypertension.  4:III108-III114. 1982
1982 The AFCR: is there life after 41?Clinical research.  30:316-321. 1982
1982 Importance of the renal nerves in established two-kidney, one clip Goldblatt hypertension.Hypertension.  4:166-174. 1982
1982 Effect of hypoxia on the conversion of angiotensin I to II in the isolated perfused rat lungBiochemical Pharmacology.  31:1375-1379. 1982
1982 1982: A critical year for hypertensionHypertension.  4:1-2. 1982
1982 Central effects of prostaglandin E2 on blood pressure and plasma renin activity in rats role of the sympathoadrenal system and vasopressinHypertension.  4:809-816. 1982
1982 Central sympathectomy with 6-hydroxydopamine prevents DOCA/NaCl hypertension by mechanisms independent of vasopressinClinical research.  30. 1982
1982 Decrease in hypothalamic norepinephrine content following renal denervation in the one-kidney, one clip goldblatt hypertensive ratHypertension.  4:369-373. 1982
1982 Decrease in sympathetic nervous system activity and attenuation in response to stress following renal denervation in the one-kidney one-clip Goldblatt hypertensive rat.Clinical and experimental hypertension.  4:707-716. 1982
1982 Decrease in sympathetic nervous system activity and attenuation in response to stress following renal denervation in the one-kidney one-clip goldblatt hypertensive ratClinical and experimental hypertension.  A4:707-716. 1982
1982 Differences between renal tubular processing of glucagon and insulinAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  11. 1982
1982 Importance of the renal Nerves in the Pathogenesis of Experimental HypertensionHypertension.  4:108-115. 1982
1982 Importance of the renal nerves in established Two-Kidney, one clip goldblatt hypertensionHypertension.  4:166-174. 1982
1982 Increased noradrenaline content of hypothalamic nuclei in association with worsening of hypertension after high sodium intake in the young spontaneously hypertensive ratClinical Science.  63. 1982
1982 Increased noradrenergic activity in hypothalamic nuclei of spontaneously hypertensive rats on high sodium intakeClinical research.  30. 1982
1982 Neuronal and adrenomedullary catecholamine release in response to cardiopulmonary bypass in manCirculation.  66:49-55. 1982
1982 Prevention of hypertension in the spontaneously hypertensive rat by chronic central administration of captoprilClinical research.  30. 1982
1982 Review of therapeutic modalities acting directly via central pathwaysClinical and experimental hypertension.  A4:579-593. 1982
1982 Review of therapeutic modalities acting directly via central pathways.Clinical and experimental hypertension.  4:579-593. 1982
1982 Sodium-neural interactions in the development of spontaneous hypertensionClinical and experimental hypertension.  A4:751-760. 1982
1982 Sodium-neural interactions in the development of spontaneous hypertension.Clinical and experimental hypertension.  4:751-760. 1982
1982 The role of calcium in the control of renin releaseHypertension.  4:670-675. 1982
1981 A progress report on hypertensionHypertension.  3:1-3. 1981
1981 Catecholamine changes during cardiopulmonary bypass: The stress response and role of the lungs in modulating itAnesthesia and Analgesia.  60:272-273. 1981
1981 Central effects of prostaglandin E2 on blood pressure and plasma renin activity: Role of the sympathoadrenal system and vasopressinClinical research.  29. 1981
1981 Decreased serum angiotensin converting enzyme in adult respiratory distress syndrome associated with sepsis: a preliminary report.Critical Care Medicine.  9:651-654. 1981
1981 Effects of sodium intake and Goldblatt hypertension on renin release in rat kidney slicesAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  9. 1981
1981 Effects of sodium intake and Goldblatt hypertension on renin release in rat kidney slicesAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  9. 1981
1981 Hypertension and oral contraceptivesJournal of Cardiovascular Medicine.  6:381-387. 1981
1981 Lofexidine and clonidine in moderate essential hypertensionClinical Pharmacology and Therapeutics.  30:752-757. 1981
1981 Prevention of DOCA/NaCl hypertension in the rat by central sympatholytic treatment is unrelated to vasopressinClinical research.  29. 1981
1981 Renal function during reflexly activated catecholamine flow through an adrenorenal reteAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  9. 1981
1981 Renal function during reflexly activated catecholamine flow through an adrenorenal reteAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  9. 1981
1981 Role of the Renal Nerves in the Pathogenesis of One-Kidney Renal Hypertension in the RatHypertension.  3:404-409. 1981
1980 Diurnal patterns and regulation of cortisol secretion in pregnancyJournal of Clinical Endocrinology and Metabolism.  51:466-472. 1980
1980 Drug management of hypertensionCirculation.  61:210-212. 1980
1980 Effect of acute hypoxia on the pulmonary conversion of angiotensin I to angiotensin II in dogsCirculation Research.  46:221-226. 1980
1980 Effect of molecular size and structure on renal tubular processing of peptides 1980
1980 Hemodynamic Response to Vascular Expansion Following Immunosympathectomy in Spontaneously Hypertensive RatsHypertension.  2:304-310. 1980
1980 Importance of Renal Sympathetic Tone in the Development of DOCA-Salt Hypertension in the RatHypertension.  2:266-273. 1980
1980 Lofexidine in essential hypertension: Double blind comparison with clonidineClinical research.  28. 1980
1980 Multiclinic double-blind evaluation of timolol combined with hydrochlorothiazide in essential hypertension 1980
1980 NMR observation of altered sodium interaction with human erythrocyte membranes of essential hypertensivesBiochemical and Biophysical Research Communications.  96:514-521. 1980
1980 Pathogenesis of paroxysmal hypertension developing during and after coronary bypass surgery: A study of hemodynamic and humoral factorsAmerican Journal of Cardiology.  46:559-565. 1980
1980 The first year of hypertensionHypertension.  2:1-2. 1980
1979 Hypertrophy in the denervated heart: A comparison of central sympatholytic treatment with 6-hydroxydopamine and peripheral sympathectomy with nerve growth factor antiserumAmerican Journal of Cardiology.  44:970-978. 1979
1979 Desoxycorticosterone in normal pregnancy. II. Cortisol-dependent fluctuations in free plasma desoxycorticosteroneAmerican Journal of Obstetrics and Gynecology.  133:644-648. 1979
1979 Hypertension: A new journalHypertension.  1:1-2. 1979
1979 Mechanism for renal tubular handling of angiotensinAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  5. 1979
1979 Mechanism for renal tubular handling of angiotensinAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  5. 1979
1979 Mechanism of angiotensin i converting enzyme inhibition by SQ20,881 (<Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro) in vivo: Further evidence for extrapulmonary conversionHypertension.  1:13-22. 1979
1979 Nomenclature for experimental renovascular hypertension. Report of the Nomenclature Committee of the Council for High Blood Pressure Research of the American Heart Association.Hypertension.  1:61. 1979
1979 Regional myocyte size in normotensive and spontaneously hypertensive ratsHypertension.  1:378-383. 1979
1979 Renal tubular handling of glucagon and insulinClinical research.  27. 1979
1979 The effect of renal denervation on the development of DOCA-salt hypertension in the ratClinical research.  27. 1979
1978 Desoxycorticosterone in normal pregnancy. I. Sequential studies of the secretory patterns of desoxycorticosterone, aldosterone, and cortisolAmerican Journal of Obstetrics and Gynecology.  132:414-420. 1978
1978 Effects of constituent amino acids on tubular handling of microinfused angiotensin II.American Journal of Physiology.  234. 1978
1978 Calcium dependence of angiotensin II induced inhibition of renin release in vitroClinical research.  26. 1978
1978 Effects of constituent amino acids on tubular handling of microinfused angiotensin IIAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  3. 1978
1978 In vivo and in vitro conversion of des-1-Asp angiotensin I to angiotensin IIIBiochemical Pharmacology.  27:2871-2877. 1978
1978 Inhibition of renin release from rat kidney slices by the angiotensinAmerican Journal of Physiology - Renal Fluid and Electrolyte Physiology.  4. 1978
1978 Inhibition of renin release from rat kidney slices by the angiotensins.American Journal of Physiology.  235. 1978
1978 Plasma angiotensin converting enzyme activity in mother and fetusJournal of Clinical Endocrinology and Metabolism.  46:434-439. 1978
1978 Report of the AFCR public policy committee: current legislative prioritiesClinical research.  26:330-332. 1978
1978 Report of the AFCR public policy committee: current legislative prioritiesClinical research.  26:121-123. 1978
1978 The mechanism of post-arrhythmic renal vasoconstriction in the dogCirculation.  58. 1978
1977 Sodium and mineralocorticoids in normal and abnormal pregnancy. 1977
1977 Changing patterns of corticoid responses to ACTH during normal pregnancyClinical research.  25. 1977
1977 Development of left ventricular hypertrophy in young spontaneously hypertensive rats after peripheral sympathectomyCirculation Research.  40:428-434. 1977
1977 Drug treatment of hypertensionCOMPR.THER..  3:34-36. 1977
1977 Handling of angiotensin II and oxytocin by renal tubular segments perfused in vitroAmerican Journal of Physiology.  232. 1977
1977 Relation of renal hemodynamics to metabolism of angiotensin II by the canine kidneyCirculation Research.  41:283-287. 1977
1977 Treatment of hypertension by computer and physician-A prospective controlled studyJournal of chronic diseases.  30:81-92. 1977
1976 Oral-Contraceptive-Induced Hypertension After Adrenalectomy and HypophysectomyArchives of Internal Medicine.  136:1029-1029. 1976
1976 Altered angiotensin I conversion in pulmonary diseaseClinical science and molecular medicine.  51:537-543. 1976
1976 Catecholamines, blood pressure, renin and myocardial function in the spontaneously hypertensive ratClinical science and molecular medicine.  51:455-459. 1976
1976 Catecholamines, blood pressure, renin and myocardial function in the spontaneously hypertensive rat.Clinical science and molecular medicine. Supplement.  3. 1976
1976 Inhibition of proximal tubular hydrolysis and reabsorption of angiotensin II by amino acidClinical research.  24. 1976
1976 Inhibition of proximal tubular hydrolysis and reabsorption of bradykinin by peptidesAmerican Journal of Physiology.  231:743-748. 1976
1976 Micropuncture evidence of rapid hydrolysis of bradykinin by rat proximal tubuleAmerican Journal of Physiology.  230:1420-1424. 1976
1976 Myocardial function and renin in the spontaneously hypertensive rat after central and peripheral sympathectomyClinical research.  24. 1976
1976 Oral-Contraceptive-Induced Hypertension After Adrenalectomy and HypophysectomyArchives of Internal Medicine.  136:1029-1031. 1976
1976 Regulation of cortisol (F) secretion in pregnancyClinical research.  24. 1976
1976 Structural requirements for the inhibition of renin release in vitro by the angiotensinsCirculation.  54. 1976
1976 Theoretical approaches to estimation of plasma renin activity: a review and some original observations 1976
1976 Treatment of essential hypertension with a combination of hydrochlorothiazide, propranolol and methyldopaClinical research.  24. 1976
1975 Plasma renin activity in hypertension.Comprehensive Therapy.  1:57-64. 1975
1975 Effect of progesterone on renal sodium handling in man: relation to aldosterone excretion and plasma renin activityClinical science and molecular medicine.  49:139-147. 1975
1975 Fate of labeled angiotensin II microinfused into individual nephrons in the ratAmerican Journal of Physiology.  228:747-751. 1975
1975 Handling of small peptides by rat renal tubulesClinical research.  23. 1975
1975 Physician acceptance of computer recommended antihypertensive therapy 1975
1975 Prevention of Hypertension in the SH Rat: Effects of Differential Central Catecholamine Depletion 1975
1974 Studies of plasma bradykininases using radiolabelled substratesAustralian Journal of Experimental Biology and Medical Science.  52:601-606. 1974
1974 Effects of ph and enzyme inhibitors on apparent generation of angiotensin i in human plasmaJournal of Clinical Endocrinology and Metabolism.  39:965-968. 1974
1974 New polypeptide inhibitors of angiotensin conversionClinical research.  22. 1974
1974 Structural requirements for substrates and inhibitors of angiotensin I converting enzyme in vivo and in vitroCirculation Research.  34:19-26. 1974
1973 Mechanism of renal handling of angiotensin II in the dogCirculation Research.  33:500-507. 1973
1973 Polypeptide inhibitors of angiotensin converting enzymeClinical research.  21:441. 1973
1973 Substrate requirements for angiotensin I conversion in vivo and in vitro.Circulation Research.  32:415-423. 1973
1971 Mechanism of pulmonary conversion of angiotensin I to angiotensin II in the dog.Circulation Research.  29:682-690. 1971
1971 Renin in differential diagnosis of hypertensionAmerican Heart Journal.  82:568-570. 1971
1970 In-vivo and in-vitro conversion of angiotensin I to angiotensin II in dog blood.Circulation Research.  26:591-599. 1970
1970 Role of renin in acute postural homeostasis.Circulation.  41:89-95. 1970
1966 Sex difference in fluid exchange during food deprivation in the rabbit.Endocrinology.  78:291-296. 1966

Book

Year Title Altmetric
2018 Impact of the SPRINT Trial on Hypertension Management.  Ed. 69.  2018
2005 Preface 2005
2005 Preface to the First Edition 2005
2005 Hypertension 2005

Chapter

Year Title Altmetric
2018 Hypertension in women.  35-47. 2018
2013 Hypertension and cardiovascular risk.  183-194. 2013
2013 Pathogenesis of Hypertension.  12-26. 2013
2012 Epidemiology of hypertension.  45-54. 2012
2012 Renin-angiotensin- aldosterone inhibitors in combination therapy.  53-64. 2012
2012 Initial evaluation and approach to the patient with hypertension.  463-473. 2012
2010 Hypertensive Emergencies.  355-367. 2010
2007 Fixed Low-Dose Antihypertensive Therapy.  1061-1073. 2007
2007 Oral Contraceptives, Hormone Replacement Therapy, and Hypertension.  865-882. 2007
2007 Pathophysiology of Hypertension.  25-46. 2007
2007 Treatment of Hypertension in the Patient with Cardiovascular Disease.  625-646. 2007
2007 Sex Steroids and Hypertension.  307-333. 2007
2005 Ischemic Heart Disease.  567-578. 2005
2005 The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT).  340-351. 2005
2005 The LIFE Study.  352-365. 2005
2004 Hypertension and Sympathetic Nervous System Activity.  241-244. 2004
Sex Hormones and Vascular Function

Principal Investigator On

  • Private Grant  awarded by IDORSIA PHARMACEUTICALS LTD 2020 - 2023
  • Blood Pressure and Kidney Function - SPRINT vs Electronic Health Record Data  awarded by University of Minnesota 2017 - 2021
  • Mechanisms of Hypertension and Cardiovascular Disease  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2021
  • 31st Annual Vascular Biology and Hypertension Symposium  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2020 - 2021
  • Evaluating the AMA/AHA eLearning Module Titled Achieving Accuracy – BP Measurement  awarded by American Medical Association Foundation 2019 - 2020
  • 30th Annual Vascular Biology and Hypertension Symposium  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2019 - 2020
  • Mechanisms of Refractory Hypertension  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2018 - 2020
  • Private Grant  awarded by Bayer HealthCare 2015 - 2019
  • Influenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated Heart Failure (INVESTED)  awarded by Brigham and Women's Hospital 2017 - 2019
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2017 - 2018
  • Systolic Blood Pressure Intervention Trial (SPRINT) Clinical Center Networks  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2018
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2015 - 2017
  • Private Grant  awarded by ASTRAZENECA AB 2013 - 2016
  • A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes After Treatment with Exenatide Once Weekly in Patients with Type 2 Diabetes Mellitus (EXSCEL)  awarded by DUKE CLINICAL RESEARCH INSTITUTE 2010 - 2016
  • Mechanisms of Hypertension and Cardiovascular Diseases  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2011 - 2016
  • Private Grant  awarded by Bayer HealthCare 2016
  • TECOS: A Randomized, Placebo Controlled Clinical Trial to Evaluate Cardiovascular Outcomes after Treatment with Sitagliptin in Patients with Type 2 Diabetes Mellitus and Inadequate Glycemic Control on Mono- or Dual Combination Oral Antihyperglycemic Therapy  awarded by Duke University 2009 - 2015
  • Private Grant  awarded by Bayer HealthCare 2014 - 2015
  • Private Grant  awarded by ARBOR PHARMACEUTICALS, LLC. 2014
  • O-GlyNAcylation: Novel Mechanism of Estrogen-Induced Vasoprotection  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2013
  • Private Grant  awarded by AMARIN PHARMA, INC. 2013
  • Private Grant  awarded by DAIICHI SANKYO, INC. 2013
  • Private Grant  awarded by TAKEDA GLOBAL RESEARCH & DEVELOPMENT CENTER 2010 - 2013
  • Private Grant  awarded by TAKEDA GLOBAL RESEARCH & DEVELOPMENT CENTER 2011 - 2013
  • Private Grant  awarded by BRISTOL MYERS SQUIBB PHARMACEUTICAL COMPANY 2012
  • Private Grant  awarded by BRISTOL MYERS SQUIBB PHARMACEUTICAL COMPANY 2012
  • Private Grant  awarded by VIVUS, INC. 2012
  • Private Grant  awarded by DAIICHI SANKYO, INC. 2012
  • Private Grant  awarded by AMGEN, INC.^ 2010 - 2011
  • Private Grant  awarded by DAIICHI SANKYO, INC. 2011
  • Integrated Regulation of Extracellular Matrix Expression in Cardiac Fibroblasts  awarded by American Heart Association 2010 - 2011
  • Mechanisms of Hypertension and Cardiovascular Diseases  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2006 - 2011
  • Private Grant  awarded by TAKEDA GLOBAL RESEARCH & DEVELOPMENT CENTER 2009 - 2011
  • Investigator On

  • Matrikines and COPD-PH COVID-19  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2019 - 2024
  • Kidney Undergraduate Research Experience (KURE)  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2018 - 2023
  • Private Grant  awarded by VASCULAR DYNAMICS INC. 2018 - 2023
  • Private Grant  awarded by RECOR MEDICAL 2020 - 2023
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2017 - 2022
  • Evaluating Novel Approaches for Estimating Awake and Sleep Blood Pressure  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2018 - 2022
  • Chronic Hypertension and Pregnancy-CHAP Clinical Coordinating Center  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2021
  • Private Grant  awarded by GE HEALTHCARE 2018 - 2021
  • Collaboration to Improve Blood Pressure in the US Black Belt- Addressing the Triple Threat  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2015 - 2021
  • Diastolic Dysfunction and Pauci-inflammatory Acute Exacerbations of Chronic Obstructive Pulmonary Disease  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2021
  • Mechanisms of Salt-Dependent Shifts in Blood Pressure Rhythms  awarded by American Heart Association 2019 - 2021
  • Sustained Blood Pressure Control and Progression of Multimorbidity  awarded by Duke University 2017 - 2021
  • Neutrophil Dysregulation as a Driving Mechanism of Cardiovascular Disease in HIV-1-Infection  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2021
  • University of Alabama at Birmingham Strategically Focused Hypertension Research Center - Mechanisms of Nocturnal Hypertension and Non-Dipping Blood Pressure - Project 2  awarded by American Heart Association 2015 - 2020
  • Coronary Flow Reserve to Assess Cardiovascular Inflammation (CIRT-CFR)  awarded by Brigham and Women's Hospital 2016 - 2020
  • Private Grant  awarded by IDORSIA PHARMACEUTICALS LTD 2018 - 2020
  • Private Grant  awarded by RECOR MEDICAL 2016 - 2019
  • Private Grant  awarded by ROX MEDICAL INC. 2018 - 2019
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2011 - 2019
  • The SPRINT· Alzheimer's, Seniors, and Kidney Study (SPRINT ASK)  awarded by WAKE FOREST UNIVERSITY 2017 - 2019
  • Cardiovascular Inflammation Reduction Trial (CIRT)  awarded by Brigham and Women's Hospital 2013 - 2019
  • University of Alabama at Birmingham Strategically Focused Hypertension Research Center  awarded by American Heart Association 2015 - 2019
  • Targeted Cell Therapy for Acute Lung Injury  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2016 - 2018
  • Private Grant  awarded by GE HEALTHCARE 2017 - 2018
  • Private Grant  awarded by GEORGE CLINICAL 2017 - 2018
  • Private Grant  awarded by MEDTRONIC, INC. 2012 - 2018
  • Mechanisms of Refractory Hypertension  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2018
  • Targeted Delivery of iPS-Endothelial Cells for the Repair of Cardiovascular Injury  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2013 - 2018
  • Centers of Research Translation (CoRT)  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2012 - 2017
  • Centers of Research Translation (CoRT) - Project 2  awarded by National Institute of Arthritis & Musculoskeletal & Skin Diseases/NIH/DHHS 2012 - 2017
  • Visit-to-Visit Variability of Blood Pressure and CVD and Renal Outcomes  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2012 - 2016
  • Private Grant  awarded by TRIVASCULAR, INC. 2010 - 2015
  • Training Program in Cardiovascular Pathophysiology  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2014 - 2015
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2014 - 2015
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2013 - 2014
  • Maintenance of Organ Function Following Injury  awarded by National Institute of General Medical Sciences/NIH/DHHS 2009 - 2014
  • Etiology of Sleep Apnea-Related Hyperaldosteronism  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2008 - 2014
  • Private Grant  awarded by NOVARTIS PHARMACEUTICALS CORPORATION 2011 - 2013
  • Cardiovascular Tissue and Cell Core  awarded by UNIVERSITY OF ALABAMA HEALTH SERVICES FOUNDATION 2009 - 2013
  • Genetics of Hypertension Associated Treatment (GENHAT)  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2007 - 2012
  • Education And Training

  • Doctor of Medicine, Columbia University 1965
  • Presbyterian Hospital, Internship 1966
  • Massachusetts General Hospital, Residency 1968
  • Presbyterian Hospital, Residency 1967
  • Massachusetts General Hospital, Postdoctoral Fellowship 1971
  • Full Name

  • Suzanne Oparil