• Dr Morgan is a registered/licensed dietitian and an internist.

    Dr. Morgan's research program has been focused on methotrexate and folic acid metabolism in patients with rheumatoid arthritis. Her work with Dr. Joseph E Baggott and members of the Division of Clinical Immunology and Rheumatology (Drs. Graciela Alarcon, Dr. William Koopman, Dr. S Louis Bridges, and Dr. Laura Hughes) have established the folic acid supplementation during low dose methotrexate therapy for rheumatoid arthritis lowers toxicity without affecting efficacy. Drs Morgan and Baggott have also studied purine metabolism and methotrexate therapy in rat adjuvant arthritis and participate in trials related to methotrexate pharmacogenetics. Dr. Morgan and Dr. Baggott have also investigated the effects of a medical food on osteoarthritis.

    As the Medical Director of the UAB Osteoporosis Prevention and Treatment Clinic, Dr. Morgan has an interest in bone densitometry and clinical trials related to osteoporosis. She has been a president of the International Society for Clinical Densitometry. She currently serves as a faculty member related to bone densitometry and vertebral fracture recognition.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 The importance of inhibition of a catabolic pathway of methotrexate metabolism in its efficacy for rheumatoid arthritis 2019
    2018 Assessment of low- and high-level task performance in people with transtibial amputation using crossover and energy-storing prosthetic feet: A pilot study 2018
    2018 Dual-task standing and walking in people with lower limb amputation: A structured review 2018
    2018 Evaluating Mild Cognitive Impairment in Essential Tremor: How Many and Which Neuropsychological Tests? 2018
    2018 Hypophosphatemia in the setting of metabolic bone disease: case reports and diagnostic algorithm 2018
    2018 Energy expenditure in people with transtibial amputation walking with crossover and energy storing prosthetic feet: A randomized within-subject study 2018
    2018 Self-report depressive symptoms are dissociated from tremor severity in essential tremor 2018
    2018 Dual-energy X-ray Absorptiometry Quality Matters 2018
    2018 Functional Outcomes in People with Transtibial Amputation Using Crossover and Energy-Storing Prosthetic Feet: A Pilot Study 2018
    2018 Laboratory- and community-based health outcomes in people with transtibial amputation using crossover and energy-storing prosthetic feet: A randomized crossover trial 2018
    2018 Association of self-reported cognitive concerns with mobility in people with lower limb loss 2018
    2017 Perceived embarrassment and caregiver burden in essential tremor caregivers 2017
    2017 Dual-task walking over a compliant foam surface: A comparison of people with transfemoral amputation and controls 2017
    2017 The cost of a patient activation intervention for achieving successful outcomes: results from the PAADRN randomized controlled trial 2017
    2017 The effects of a patient activation intervention on smoking and excessive drinking cessations: results from the PAADRN randomized controlled trial 2017
    2017 The experience of essential tremor caregivers: Burden and its correlates 2017
    2017 Erratum to: Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot study (Osteoporosis International, (2017), 28, 8, (2495-2503), 10.1007/s00198-017-4073-5) 2017
    2017 Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot study 2017
    2017 Mild Cognitive Impairment Subtypes in a Cohort of Elderly Essential Tremor Cases 2017
    2017 Cognitive dysfunction is associated with greater imbalance and falls in essential tremor 2017
    2017 Case-Based Review of Osteonecrosis of the Jaw (ONJ) and Application of the International Recommendations for Management From the International Task Force on ONJ 2017
    2017 Prosthetists’ perceptions and use of outcome measures in clinical practice: Long-term effects of focused continuing education 2017
    2017 Psychological Suffering in Essential Tremor: A Study of Patients and Those Who Are Close to Them 2017
    2016 Daytime sleepiness and nighttime sleep quality across the full spectrum of cognitive presentations in essential tremor 2016
    2016 Characterizing mobility from the prosthetic limb user's perspective: Use of focus groups to guide development of the Prosthetic Limb Users Survey of Mobility 2016
    2016 Self-reported physical activity in essential tremor: Relationship with tremor, balance, and cognitive function 2016
    2016 Pelvic Floor Symptoms and Spinal Curvature in Women 2016
    2016 Protein Requirements in Illness: Considerations for Acute Care Nurse Practitioners 2016
    2016 Osteoporosis and imaging: The big picture 2016
    2016 Best Practices for Dual-Energy X-ray Absorptiometry Measurement and Reporting: International Society for Clinical Densitometry Guidance 2016
    2016 Re-emergent tremor of Parkinson’s disease masquerading as essential tremor 2016
    2016 Psychometric evaluation of self-report outcome measures for prosthetic applications 2016
    2016 The effects of a concurrent task on walking in persons with transfemoral amputation compared to persons without limb loss 2016
    2015 Diagnosis and management of osteonecrosis of the jaw: A systematic review and international consensus 2015
    2015 Use of and confidence in administering outcome measures among clinical prosthetists: Results from a national survey and mixed-methods training program 2015
    2014 Genetic variants associated with methotrexate efficacy and toxicity in early rheumatoid arthritis: Results from the treatment of early aggressive rheumatoid arthritis trial 2014
    2014 Evaluation of a Computer-Tailored Osteoporosis Prevention Intervention in Young Women 2014
    2014 Hajdu-Cheney syndrome: Phenotypical progression with de-novo NOTCH2 mutation 2014
    2014 The Effect of Extending Femur Scan Length on BMD Results on the Hologic Discovery-W Scanner 2014
    2014 Use of cognitive interviews in the development of the PLUS-M item bank 2014
    2013 Celiac Disease and Metabolic Bone Disease 2013
    2013 Dietary Supplements and Medical Foods for Osteopenia and Osteoporosis 2013
    2013 Eating Disorders and Bone 2013
    2013 Introduction From the Guest Editors 2013
    2013 Decreased bone mineral density and periodontal management 2013
    2013 Pelvic floor symptoms and bone mineral density in women undergoing osteoporosis evaluation 2013
    2013 The PAADRN Study: A design for a randomized controlled practical clinical trial to improve bone health 2013
    2012 A randomized trial of a mailed intervention and self-scheduling to improve osteoporosis screening in postmenopausal women 2012
    2012 Association of the presence of bone bars on radiographs and hip fracture in postmenopausal Caucasian women 2012
    2012 Markers of treatment response to methotrexate in rheumatoid arthritis: Where do we stand? 2012
    2012 Proceedings of the 2011 Santa Fe Bone Symposium 2012
    2012 Which to Use to Evaluate Change in BMD at Follow-Up: RMS-SD or RMS-%CV? 2012
    2011 Association of the presence of bone bars on radiographs and low bone mineral density 2011
    2011 Obesity, bariatric surgery, and bone 2011
    2011 Phenotypes and circadian rhythm in utilization of formate in purine nucleotide biosynthesis de novo in adult humans 2011
    2011 Long-Term Versus Short-Term Precision of Dual-Energy X-Ray Absorptiometry Scans and the Impact on Interpreting Change in Bone Mineral Density at Follow-up 2011
    2011 Trends in Dual-Energy X-Ray Absorptiometry in the United States, 2000-2009 2011
    2010 Folate supplementation during Methotrexate therapy for rheumatoid arthritis 2010
    2010 Current status of clinical 25-hydroxyvitamin D measurement: An assessment of between-laboratory agreement 2010
    2010 Algorithm for the Management of Osteoporosis 2010
    2010 Distribution of Z-Scores in a university cohort with an emphasis on "high" bone mineral density 2010
    2010 Measurement of erythrocyte methotrexate polyglutamate levels: Ready for clinical use in rheumatoid arthritis? 2010
    2010 Folate supplementation during methotrexate therapy for rheumatoid arthritis. 2010
    2009 Nutrition and bone: It is more than calcium and vitamin D 2009
    2009 The safety of flavocoxid, a medical food, in the dietary management of knee osteoarthritis 2009
    2009 Tone the Bones of Your Chronic Liver Disease Patients 2009
    2008 The Effect of Peritoneal Dialysate on DXA Bone Densitometry Results in Patients with End-Stage Renal Disease 2008
    2008 Osteoporosis: Handy tools for detection, helpful tips for treatment 2008
    2008 "Black Hole Artifacts"-A New Potential Pitfall for DXA Accuracy? 2008
    2008 Comparing BMD Results Between Two Similar DXA Systems Using the Generalized Least Significant Change 2008
    2008 The Effect of Common Artifacts Lateral to the Spine on Bone Mineral Density in the Lumbar Spine 2008
    2007 Comment on "Nutritional gain versus financial gain: the role of metabolic carts in the surgical ICU". 2007
    2007 Letters to the editor [8] 2007
    2007 Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism 2007
    2007 Not just calcium and vitamin D: Other nutritional considerations in osteoporosis 2007
    2006 Medical foods: Products for the management of chronic diseases 2006
    2006 Nonprogression of Vertebral Area or Bone Mineral Content on DXA Does Not Predict Compression Fractures 2006
    2004 Effect of methotrexate therapy on bone mineral density and body composition in rat adjuvant arthritis 2004
    2004 Letter to the editor [2] (multiple letters) 2004
    2003 Combined oral cyclosporin and methotrexate therapy in patients with rheumatoid arthritis elevates methotrexate levels and reduces 7-hydroxymethotrexate levels when compared with methotrexate alone 2003
    2003 Nutritional considerations in osteoporosis 2003
    2003 Need for precision studies at individual institutions and assessment of size of regions of interest on serial DXA scans 2003
    2001 MTX affects inflammation and tissue destruction differently in the rat AA model 2001
    2001 Calcium and vitamin D in osteoporosis 2001
    2001 “Tone Your Bones” A Model for Health Education for Older Adults 2001
    1999 Comparison of a computer-based food frequency questionnaire for calcium intake with 2 other assessment tools 1999
    1998 Folic acid supplementation prevents deficient blood [1] (multiple letters) 1998
    1998 Hyperhomocysteinemia as a cause of vascular occlusion in end-stage-renal disease 1998
    1998 Folic acid supplementation prevents deficient blood folate levels and hyperhomocysteinemia during longterm, low dose methotrexate therapy for rheumatoid arthritis: Implications for cardiovascular disease prevention 1998
    1997 Obesity: Is there effective treatment now? 1997
    1997 Methotrexate in rheumatoid arthritis. Folate supplementation should always be given 1997
    1997 The use of an enteral expert system in the prescription of enteral formulas in a university hospital 1997
    1996 Folinic acid to prevent side effects of methotrexate in juvenile rheumatoid arthritis [3] 1996
    1996 The use of circulatory indirect calorimetry in critically ill patients 1996
    1996 Metabolic complications of total parenteral nutrition: Effects of a nutrition support service 1996
    1996 Overfeeding in a patient with Kwashiorkor syndrome 1996
    1995 Remote communication from a mobile terminal: An adjunct for a computerized intensive care unit order management system 1995
    1995 Identification of indicators for improving the diagnosis of malnutrition. 1995
    1995 Adverse events in methotrexate-treated rheumatoid arthritis patients 1995
    1995 Adverse events in methotrexate-treated rheumatoid arthritis patients 1995
    1993 Modification of a high-performance liquid chromatographic method for assay of homocysteine in human plasma 1993
    1993 Antifolates in rheumatoid arthritis: A hypothetical mechanism of action 1993
    1993 Folic acid supplementation during methotrexate therapy: It makes sense 1993
    1993 Hospital-associated malnutrition: A reevaluation 12 years later 1993
    1993 MR imaging of the hands in early rheumatoid arthritis: preliminary results. 1993
    1993 Multiple vitamin preparations: Practical formulation and classification for prescribing 1993
    1992 A meal conference format to teach ambulatory nutrition concepts 1992
    1991 Homocysteine levels in patients with rheumatoid arthritis treated with low‐dose methotrexate 1991
    1991 “U R what U eat” 1991
    1990 Activated lymphocytes in peripheral blood of patients with RA 1990
    1990 Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation 1990
    1990 Registered dietitians: Assuming a more active role in medical education 1990
    1990 “Nutrition: Your passport to good health”— An innovative luncheon 1990
    1989 Rational Weight Loss Programs: A Clinician’s Guide 1989
    1989 Nutrition education for medical students: Evaluation of the relative contribution of freshman courses in biochemistry and nutrition to performance on a standardized examination in nutrition 1989
    1988 A comparison of nutrition knowledge of freshmen and senior medical students: A collaborative study of southeastern medical schools 1988
    1988 Re: Methotrexate in the treatment of arthritis and connective tissue disease 1988


    Year Title Altmetric
    2012 Nutrition and diet in rheumatic and arthritic diseases.  1245-1260. 2012
    2012 Life review with people with dementia in care homes: A preliminary randomized controlled trial.  43-59. 2012
    2009 Osteoporosis.  393-404. 2009
    2006 12 - Therapeutic Diets.  282-309. 2006
    2006 24 - Pulmonary Disease.  503-509. 2006
    2006 26 - Anemias.  523-540. 2006
    2006 28 - Metabolic bone disease.  554-565. 2006

    Research Overview

  • Bone densitometry, osteoporosis, methotrexate and folate metabolism in rheumatoid arthritis
  • Principal Investigator On

    Investigator On

    Education And Training

  • Doctor of Medicine, University of Iowa 1981
  • Full Name

  • Sarah Morgan