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Shinichi Kano
Associate Professor
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E-mail
skano@uab.edu
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Map of Science
Co-investigator Network
Shinichi Kano
Associate Professor
Positions
Scientist (C)
,
UAB Immunology Institute
,
School of Medicine
Scientist (C)
,
UWIRC Microbiome Center
,
School of Medicine
Scientist (C)
,
Comprehensive Neuroscience Center
,
General Clinical Research Center
Scientist (C)
,
Neurodegeneration and Experimental Therapeutics (CNET)
,
Neurology
Scientist (C)
,
Alzheimer's Disease Center
,
Neurology
Associate Professor (P)
,
Psychiatry - Behavioral Neurobiology
,
Psychiatry
Scientist (C)
,
Civitan International Research Center
,
Academic Joint Departments
Associate Professor (S)
,
Neurobiology
,
Academic Joint Departments
Publications
Research
Teaching
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
Altmetric
2022
Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry
.
Nature
. 610:327-334.
2022
2021
Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice
.
FEBS Open Bio
. 11:2678-2692.
2021
2020
Forskolin rapidly enhances neuron-like morphological change of directly induced-neuronal cells from neurofibromatosis type 1 patients
.
Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology
. 40:396-400.
2020
2020
Host–parasite interaction associated with major mental illness
.
Molecular Psychiatry
. 25:194-205.
2020
2020
Reply to Brune M and Theiss C: Remaining questions in the relationship between T. gondii infection and major mental illness
.
Molecular Psychiatry
. 25:4-5.
2020
2019
The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood
.
Schizophrenia Research
. 210:149-156.
2019
2019
Extracellular Vesicles for Research on Psychiatric Disorders.
.
Schizophrenia Bulletin
. 45:7-16.
2019
2019
Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation
.
Science Signaling
. 12.
2019
2018
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines
.
Journal of Extracellular Vesicles
. 7.
2018
2017
Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: A pilot study
.
Scientific Reports
. 7.
2017
2017
Behavioral changes in mice lacking interleukin-33
.
eNeuro
. 4.
2017
2016
A critical period of vulnerability to adolescent stress: Epigenetic mediators in mesocortical dopaminergic neurons
.
Human Molecular Genetics
. 25:1370-1381.
2016
2016
Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls.
2016
2015
Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities.
.
Neuroscience Research
. 101:57-61.
2015
2013
Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders.
.
Neuroscience Research
. 77:247-250.
2013
2013
Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis.
.
Neurobiology of Disease
. 59:63-68.
2013
2013
Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia.
.
Molecular Psychiatry
. 18:740-742.
2013
2013
MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients.
.
Neurobiology of Disease
. 55:1-10.
2013
2013
Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice.
.
Glia
. 61:679-693.
2013
2013
Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids
.
Science
. 339:335-339.
2013
2012
Mouse strain differences in phencyclidine-induced behavioural changes
.
International Journal of Neuropsychopharmacology
. 15:767-779.
2012
2011
Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia
.
Neuroscience Research
. 71:289-293.
2011
2011
A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression.
.
Neuroscience Research
. 69:154-160.
2011
2010
Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade.
2010
2008
The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells.
.
Nature Immunology
. 9:34-41.
2008
2005
Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.
.
Nature
. 434:243-249.
2005
Research
Principal Investigator On
Altered microRNA Expression Patterns in Plasma Extracellular Vesicles from Patients with First Episode Psychosis
awarded by
National Institute of Mental Health/NIH/DHHS
Impact of Immune Cell-Derived Exosomes and miRNAs on Brain Function and Behavior
awarded by
National Institute of Mental Health/NIH/DHHS
Influence Of Thalamic IL-33 Signaling in Aging-Associated Exacerbation of Cognitive Impairment After Brain Injury Via Microglial Dysfunction and Tau Pathology
awarded by
National Institute on Aging/NIH/DHHS
Requirement of Astrocyte-Derived Immune Signaling For the Hippocampal-Cortical Circuit for Social Novelty Recognition
awarded by
National Institute of Mental Health/NIH/DHHS
Teaching
Teaching Activities
BME698 - Non-Thesis Research (Fall Term 2019)
GBSC720 - Journal Club 2 (Spring Term 2022)
Background
Education And Training
Doctor of Philosophy in Immunology,
The University of Tokyo
2006
Doctor of Medicine,
The University of Tokyo
2002
Contact
Full Name
Shinichi
Kano