Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Prenatal immune stress blunts microglia reactivity, impairing neurocircuitry.  Nature.  610:327-334. 2022
2021 Alterations in circulating extracellular vesicles underlie social stress-induced behaviors in mice.  FEBS Open Bio.  11:2678-2692. 2021
2020 Forskolin rapidly enhances neuron-like morphological change of directly induced-neuronal cells from neurofibromatosis type 1 patients.  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology.  40:396-400. 2020
2020 Host–parasite interaction associated with major mental illness.  Molecular Psychiatry.  25:194-205. 2020
2020 Reply to Brune M and Theiss C: Remaining questions in the relationship between T. gondii infection and major mental illness.  Molecular Psychiatry.  25:4-5. 2020
2019 The transcriptome landscape associated with Disrupted-in-Schizophrenia-1 locus impairment in early development and adulthood.  Schizophrenia Research.  210:149-156. 2019
2019 Extracellular Vesicles for Research on Psychiatric Disorders..  Schizophrenia Bulletin.  45:7-16. 2019
2019 Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation.  Science Signaling.  12. 2019
2018 Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.  Journal of Extracellular Vesicles.  7. 2018
2017 Dysregulated gene expressions of MEX3D, FOS and BCL2 in human induced-neuronal (iN) cells from NF1 patients: A pilot study.  Scientific Reports.  7. 2017
2017 Behavioral changes in mice lacking interleukin-33.  eNeuro.  4. 2017
2016 A critical period of vulnerability to adolescent stress: Epigenetic mediators in mesocortical dopaminergic neurons.  Human Molecular Genetics.  25:1370-1381. 2016
2016 Infection and characterization of Toxoplasma gondii in human induced neurons from patients with brain disorders and healthy controls. 2016
2015 Enhanced conversion of induced neuronal cells (iN cells) from human fibroblasts: Utility in uncovering cellular deficits in mental illness-associated chromosomal abnormalities..  Neuroscience Research.  101:57-61. 2015
2013 Olfactory cells via nasal biopsy reflect the developing brain in gene expression profiles: utility and limitation of the surrogate tissues in research for brain disorders..  Neuroscience Research.  77:247-250. 2013
2013 Cuprizone short-term exposure: astrocytic IL-6 activation and behavioral changes relevant to psychosis..  Neurobiology of Disease.  59:63-68. 2013
2013 Genome-wide profiling of multiple histone methylations in olfactory cells: further implications for cellular susceptibility to oxidative stress in schizophrenia..  Molecular Psychiatry.  18:740-742. 2013
2013 MicroRNA-382 expression is elevated in the olfactory neuroepithelium of schizophrenia patients..  Neurobiology of Disease.  55:1-10. 2013
2013 Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice..  Glia.  61:679-693. 2013
2013 Adolescent stress-induced epigenetic control of dopaminergic neurons via glucocorticoids.  Science.  339:335-339. 2013
2012 Mouse strain differences in phencyclidine-induced behavioural changes.  International Journal of Neuropsychopharmacology.  15:767-779. 2012
2011 Altered MHC class I expression in dorsolateral prefrontal cortex of nonsmoker patients with schizophrenia.  Neuroscience Research.  71:289-293. 2011
2011 A novel balanced chromosomal translocation found in subjects with schizophrenia and schizotypal personality disorder: altered l-serine level associated with disruption of PSAT1 gene expression..  Neuroscience Research.  69:154-160. 2011
2010 Disrupted-in-Schizophrenia-1 expression is regulated by beta-site amyloid precursor protein cleaving enzyme-1-neuregulin cascade. 2010
2008 The contribution of transcription factor IRF1 to the interferon-gamma-interleukin 12 signaling axis and TH1 versus TH-17 differentiation of CD4+ T cells..  Nature Immunology.  9:34-41. 2008
2005 Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors..  Nature.  434:243-249. 2005

Education And Training

  • Doctor of Philosophy in Immunology, The University of Tokyo 2006
  • Doctor of Medicine, The University of Tokyo 2002

    • Full Name

  • Shinichi Kano