Year |
Title |
Altmetric |
2022
|
Augmented Cardiac Growth Hormone Signaling Contributes to Cardiomyopathy Following Genetic Disruption of the Cardiomyocyte Circadian Clock.
Frontiers in Pharmacology.
13.
2022
|
|
2021
|
Very Low Vitamin D in a Patient with a Novel Pathogenic Variant in the GC Gene That Encodes Vitamin D-Binding Protein.
Journal of the Endocrine Society.
5.
2021
|
|
2021
|
Branched chain amino acids selectively promote cardiac growth at the end of the awake period.
Journal of Molecular and Cellular Cardiology.
157:31-44.
2021
|
|
2021
|
Impact of obesity on day-night differences in cardiac metabolism
2021
|
|
2021
|
Physiology of GH action and associated human disorders.
Molecular and Cellular Endocrinology.
520.
2021
|
|
2020
|
Classical and novel GH receptor signaling pathways.
Molecular and Cellular Endocrinology.
518.
2020
|
|
2020
|
A small molecule, UAB126, reverses diet-induced obesity and its associated metabolic disorders.
Diabetes.
69:2003-2016.
2020
|
|
2020
|
Differential effects of REV-ERB/ agonism on cardiac gene expression, metabolism, and contractile function in a mouse model of circadian disruption
2020
|
|
2020
|
Insulin-Like Growth Factors Are Key Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity.
Immunity.
52:650-667.e10.
2020
|
|
2020
|
Autocrine/paracrine actions of growth hormone in human melanoma cell lines.
Biochemistry and Biophysics Reports.
21.
2020
|
|
2019
|
Growth hormone (GH) receptor (GHR)-specific inhibition of GH-Induced signaling by soluble IGF-1 receptor (sol IGF-1R).
Molecular and Cellular Endocrinology.
492.
2019
|
|
2018
|
Moving Career Development Upstream: Evaluation of a Course for Internal Medicine Trainees Contemplating Career Pathways in Academic Medicine.
Southern Medical Journal.
111:471-475.
2018
|
|
2018
|
Differential tissue response to growth hormone in mice.
FEBS Open Bio.
8:1146-1154.
2018
|
|
2018
|
Temporal partitioning of adaptive responses of the murine heart to fasting.
Life Sciences.
197:30-39.
2018
|
|
2018
|
Effects of rapamycin on growth hormone receptor knockout mice
2018
|
|
2017
|
Subdomain 2, not the transmembrane domain, determines the dimerization partner of growth hormone receptor and prolactin receptor
2017
|
|
2017
|
Genetic disruption of the cardiomyocyte circadian clock differentially influences insulin-mediated processes in the heart.
Journal of Molecular and Cellular Cardiology.
110:80-95.
2017
|
|
2017
|
Molecular interactions of EphA4, growth hormone receptor, Janus kinase 2, and signal transducer and activator of transcription 5B.
PLoS One.
12.
2017
|
|
2017
|
Insulin, IGF-1, and GH receptors are altered in an adipose tissue depot-specific manner in male mice with modified GH action
2017
|
|
2016
|
TIMP3 modulates GHR abundance and GH sensitivity
2016
|
|
2016
|
Calcium channel blocker use is associated with lower fasting serum glucose among adults with diabetes from the REGARDS study.
Diabetes Research and Clinical Practice.
115:115-121.
2016
|
|
2016
|
GHR/PRLR heteromultimer is composed of GHR homodimers and PRLR homodimers
2016
|
|
2015
|
Augmented STAT5 signaling bypasses multiple impediments to lactogen-mediated proliferation in human β-cells.
Diabetes.
64:3784-3797.
2015
|
|
2015
|
Growth hormone inhibits hepatic de novo lipogenesis in adult mice.
Diabetes.
64:3093-3103.
2015
|
|
2014
|
Human GH receptor-IGF-1 receptor interaction: implications for GH signaling
2014
|
|
2014
|
Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β
2014
|
|
2014
|
Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells
2014
|
|
2014
|
Circadian clock control of endocrine factors.
Nature Reviews Endocrinology.
10:466-475.
2014
|
|
2014
|
Dynamic analysis of gh receptor conformational changes by split luciferase complementation
2014
|
|
2014
|
Human gh Receptor-Igf-1 receptor interaction: Implications for gh signaling
2014
|
|
2013
|
IGF-1R modulation of acute GH-induced STAT5 signaling: Role of protein tyrosine phosphatase activity
2013
|
|
2013
|
Hepatic growth hormone resistance after acute injury
2013
|
|
2013
|
The role of GH in adipose tissue: Lessons from adipose-specific GH receptor gene-disrupted mice
2013
|
|
2013
|
The role of prolactin receptor in GH signaling in breast cancer cells
2013
|
|
2013
|
Effects of insulin and IGF-I on growth hormone- induced STAT5 activation in 3T3-F442A adipocytes.
Lipids in Health and Disease.
12.
2013
|
|
2012
|
Noninvasive bioluminescence imaging in small animals
2012
|
|
2012
|
Growth hormone-induced JAK2 signaling and GH receptor down-regulation: Role of GH receptor intracellular domain tyrosine residues
2012
|
|
2012
|
Innate dysfunction promotes linear growth failure in pediatric Crohn's disease and growth hormone resistance in murine ileitis.
Inflammatory Bowel Diseases.
18:236-245.
2012
|
|
2011
|
Inhibitory GH receptor extracellular domain monoclonal antibodies: Three-dimensional epitope mapping
2011
|
|
2011
|
Signaling cross talk between growth hormone (GH) and insulin-like growth factor-I (IGF-I) in pancreatic islet β-cells
2011
|
|
2011
|
ACK2-dependent mechanism for activation of the JAK-STAT signaling pathway.
Blood.
118:156-166.
2011
|
|
2011
|
γ-Secretase-mediated growth hormone receptor proteolysis: Mapping of the intramembranous cleavage site.
Biochemical and Biophysical Research Communications.
408:432-436.
2011
|
|
2011
|
Growth hormone signaling in human T47D breast cancer cells: Potential role for a growth hormone Receptor-Prolactin receptor complex
2011
|
|
2011
|
Synergy in ERK activation by cytokine receptors and tyrosine kinase growth factor receptors.
Cellular Signalling.
23:417-424.
2011
|
|
2010
|
Distinct growth hormone receptor signaling modes regulate skeletal muscle development and insulin sensitivity in mice.
Journal of Clinical Investigation.
120:4007-4020.
2010
|
|
2010
|
Deletion of IGF-I receptor (IGF-IR) in primary osteoblasts reduces GH-induced STAT5 signaling
2010
|
|
2010
|
Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growth.
Nature Medicine.
16:219-223.
2010
|
|
2010
|
Erratum to "Effects of diabetes mellitus in patients with heart failure and chronic kidney disease: A propensity-matched study of multimorbidity in chronic heart failure" [Int. J. Cardiol. 134 (2009) 330-335] (DOI:10.1016/j.ijcard.2008.12.089).
International Journal of Cardiology.
138:106.
2010
|
|
2010
|
Growth hormone receptor targeting to lipid rafts requires extracellular subdomain 2.
Biochemical and Biophysical Research Communications.
391:414-418.
2010
|
|
2009
|
Effects of diabetes mellitus in patients with heart failure and chronic kidney disease: A propensity-matched study of multimorbidity in chronic heart failure.
International Journal of Cardiology.
134:330-335.
2009
|
|
2009
|
Extreme elevation of serum growth hormone-binding protein concentrations resulting from a novel heterozygous splice site mutation of the growth hormone receptor gene
2009
|
|
2009
|
Erratum: Mode of growth hormone action in osteoblasts (Journal of Biological Chemistry (2007) vol. 282 (31666-31674)).
Journal of Biological Chemistry.
284:10992.
2009
|
|
2009
|
Interruption of growth hormone signaling via SHC and ERK in 3T3-F442A preadipocytes upon knockdown of insulin receptor substrate-1
2009
|
|
2008
|
Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system
2008
|
|
2008
|
ERK-dependent threonine phosphorylation of EGF receptor modulates receptor downregulation and signaling.
Cellular Signalling.
20:2145-2155.
2008
|
|
2008
|
Tight blood glucose control (1).
Geriatrics.
63:3.
2008
|
|
2008
|
Endotoxin-induced proteolytic reduction in hepatic growth hormone (GH) receptor: A novel mechanism for GH insensitivity
2008
|
|
2008
|
Activation of growth hormone receptors by growth hormone and growth hormone antagonist dimers: Insights into receptor triggering
2008
|
|
2008
|
Prolactin stimulates ubiquitination, initial internalization, and degradation of its receptor via catalytic activation of Janus kinase 2.
Journal of Endocrinology.
196.
2008
|
|
2008
|
Mechanistic aspects of crosstalk between GH and PRL and ErbB receptor family signaling.
Journal of Mammary Gland Biology and Neoplasia.
13:119-129.
2008
|
|
2008
|
Noninvasive bioluminescence imaging in small animals
2008
|
|
2007
|
Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells
2007
|
|
2007
|
Photic injury promotes cleavage of p75NTR by TACE and nuclear trafficking of the p75 intracellular domain.
Molecular and Cellular Neuroscience.
36:449-461.
2007
|
|
2007
|
Mode of growth hormone action in osteoblasts.
Journal of Biological Chemistry.
282:31666-31674.
2007
|
|
2007
|
Effect of nutrition on the GH responsiveness of liver and adipose tissue in dairy cows.
Journal of Endocrinology.
195:49-58.
2007
|
|
2007
|
Combined effect of mutations of the GH1 gene and its proximal promoter region in a child with growth hormone neurosecretory dysfunction (GHND).
Journal of Molecular Medicine.
85:1005-1013.
2007
|
|
2007
|
A growth hormone receptor mutation impairs growth hormone autofeedback signaling in pituitary tumors.
Cancer Research.
67:7505-7511.
2007
|
|
2007
|
Determinants of growth hormone receptor down-regulation
2007
|
|
2007
|
Growth hormone stimulates hepatic expression of bovine growth hormone receptor messenger ribonucleic acid through signal transducer and activator of transcription 5 activation of a major growth hormone receptor gene promoter
2007
|
|
2007
|
Role of the Growth Hormone (GH) receptor transmembrane domain in receptor predimerization and GH-induced activation
2007
|
|
2007
|
Identification of the glomerular podocyte as a target for growth hormone action
2007
|
|
2007
|
Growth hormone, insulin-like growth factor I, and growth: Local knowledge
2007
|
|
2007
|
Tumour necrosis factor α blockade induces an anti-inflammatory growth hormone signalling pathway in experimental colitis.
Gut.
56:73-81.
2007
|
|
2006
|
Prolactin modulates phosphorylation, signaling and trafficking of epidermal growth factor receptor in human T47D breast cancer cells.
Oncogene.
25:7565-7576.
2006
|
|
2006
|
In vivo imaging of hepatic growth hormone signaling
2006
|
|
2006
|
Growth hormone/JAK-STAT axis signal-transduction defect: A novel treatable cause of growth failure
2006
|
|
2006
|
Janus kinase 2 influences growth hormone receptor metalloproteolysis
2006
|
|
2006
|
A mutant signal transducer and activator of transcription 5b, associated with growth hormone insensitivity and insulin-like growth factor-I deficiency, cannot function as a signal transducer or transcription factor.
Journal of Clinical Endocrinology and Metabolism.
91:1526-1534.
2006
|
|
2006
|
Insulin enhances growth hormone induction of the MEK/ERK signaling pathway.
Journal of Biological Chemistry.
281:982-992.
2006
|
|
2006
|
Signal transducer and activator of transcription 5b promotes mucosal tolerance in pediatric Crohn's disease and murine colitis.
American Journal of Pathology.
169:1999-2013.
2006
|
|
2005
|
Janus kinase 2 enhances the stability of the mature growth hormone receptor
2005
|
|
2005
|
Growth hormone receptor is a target for presenilin-dependent γ-secretase cleavage.
Journal of Biological Chemistry.
280:19331-19342.
2005
|
|
2005
|
Partial redirection of transgenic human growth hormone secretion from rat salivary glands.
Human gene therapy. Clinical development.
16:571-583.
2005
|
|
2005
|
Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of Jak2 tyrosine kinase autophophorylation.
Journal of Medicinal Chemistry.
48:2526-2533.
2005
|
|
2004
|
A conformationally sensitive GHR [Growth Hormone (GH) Receptor] antibody: Impact on GH signaling and GHR proteolysis
2004
|
|
2004
|
Microarray analyses identify JAK2 tyrosine kinase as a key mediator of ligand-independent gene expression
2004
|
|
2004
|
Growth hormone alters epidermal growth factor receptor binding affinity via activation of extracellular signal-regulated kinases in 3T3-F442A cells
2004
|
|
2004
|
Physical and functional interaction of growth hormone and insulin-like growth factor-I signaling elements
2004
|
|
2004
|
Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: Impact on growth hormone signaling.
Journal of Biological Chemistry.
279:20898-20905.
2004
|
|
2004
|
Dairy cows experience selective reduction of the hepatic growth hormone receptor during the periparturient period.
Journal of Endocrinology.
181:281-290.
2004
|
|
2004
|
Insulin Increases the Abundance of the Growth Hormone Receptor in Liver and Adipose Tissue of Periparturient Dairy Cows
2004
|
|
2003
|
Janus Kinase 2 Determinants for Growth Hormone Receptor Association, Surface Assembly, and Signaling
2003
|
|
2003
|
Reduced Proteolysis of Rabbit Growth Hormone (GH) Receptor Substituted with Mouse GH Receptor Cleavage Site
2003
|
|
2003
|
Effects of chronic ethanol on hepatic and renal CYP2C11 in the male rat: Interactions with the Janus-kinase 2-signal transducer and activators of transcription proteins 5b pathway
2003
|
|
2003
|
Ovine placental lactogen-induced heterodimerization of ovine growth hormone and prolactin receptors in living cells is demonstrated by fluorescence resonance energy transfer microscopy and leads to prolonged phosphorylation of signal transducer and activator of transcription (STAT)1 and STAT3
2003
|
|
2003
|
Growth hormone-induced phosphorylation of epidermal growth factor (EGF) receptor in 3T3-F442A cells: Modulation of EGF-induced trafficking and signaling.
Journal of Biological Chemistry.
278:18902-18913.
2003
|
|
2003
|
Interleukin-6 inhibits hepatic growth hormone signaling via upregulation of Cis and Socs-3
2003
|
|
2002
|
Metalloprotease-mediated GH receptor proteolysis and GHBP shedding: Determination of extracellular domain stem region cleavage site.
Journal of Biological Chemistry.
277:50510-50519.
2002
|
|
2002
|
A role for Grb2-associated binder-1 in growth hormone signaling
2002
|
|
2002
|
Metalloproteinases and the modulation of GH signaling.
Journal of Endocrinology.
174:361-368.
2002
|
|
2002
|
Growth hormone-induced differential desensitization of STAT5, ERK, and Akt phosphorylation.
Journal of Biological Chemistry.
277:28384-28393.
2002
|
|
2002
|
Impairment of Liver GH Receptor Signaling by Fasting..
Endocrinology.
143:792-800.
2002
|
|
2002
|
Impairment of liver GH receptor signaling by fasting
2002
|
|
2002
|
Minireview: Receptor Dimerization in GH and Erythropoietin Action-It Takes Two to Tango, But How?.
Endocrinology.
143:2-10.
2002
|
|
2002
|
Minireview: Receptor dimerization in GH and erythropoietin action - It takes two to Tango, but how?
2002
|
|
2001
|
Growth Hormone (GH)-induced Dimerization Inhibits Phorbol Ester-stimulated GH Receptor Proteolysis.
Journal of Biological Chemistry.
276:24565-24573.
2001
|
|
2001
|
Demonstration of Direct Effects of Growth Hormone on Neonatal Cardiomyocytes.
Journal of Biological Chemistry.
276:22892-22900.
2001
|
|
2001
|
Pulmonary hypoplasia in mice lacking tumor necrosis factor-α converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis.
Developmental Biology.
232:204-218.
2001
|
|
2001
|
The Angiotensin II-dependent Nuclear Translocation of Stat1 is Mediated by the Jak2 Protein Motif 231YRFRR.
Journal of Biological Chemistry.
276:10556-10563.
2001
|
|
2001
|
Constitutive α-secretase cleavage of the β-amyloid precursor protein in the furin-deficient LoVo cell line: Involvement of the pro-hormone convertase 7 and the disintegrin metalloprotease ADAM10.
Journal of Neurochemistry.
76:1532-1539.
2001
|
|
2001
|
Src homology 3 domain-dependent interaction of Nck-2 with insulin receptor substrate-1.
Biochemical Journal.
354:315-322.
2001
|
|
2001
|
Growth hormone signalling and its regulation: Preventing too much of a good thing.
Growth Hormone and IGF Research.
11:201-212.
2001
|
|
2001
|
Phorbol ester- and growth factor-induced growth hormone (GH) receptor proteolysis and GH-binding protein shedding: Relationship to GH receptor down-regulation
2001
|
|
2000
|
Tumor Necrosis Factor-α Converting Enzyme (TACE) Is a Growth Hormone Binding Protein (GHBP) Sheddase: The Metalloprotease TACE/ADAM-17 Is Critical for (PMA-Induced) GH Receptor Proteolysis and GHBP Generation..
Endocrinology.
141:4342-4348.
2000
|
|
2000
|
Insulin receptor substrate-1-mediated enhancement of growth hormone-induced mitogen-activated protein kinase activation
2000
|
|
2000
|
Tumor necrosis factor-α converting enzyme (TACE) is a growth hormone binding protein (GHBP) sheddase: The metalloprotease TACE/ADAM-17 is critical for (PMA-induced) GH receptor proteolysis and GHBP generation
2000
|
|
1999
|
Growth hormone-induced alteration in ErbB-2 phosphorylation status in 3T3-F442A fibroblasts.
Journal of Biological Chemistry.
274:36015-86024.
1999
|
|
1999
|
A catalytically active Jak2 is required for the angiotensin II-dependent activation of Fyn.
Journal of Biological Chemistry.
274:33131-33142.
1999
|
|
1999
|
Disulfide linkage of growth hormone (GH) receptors (GHR) reflects GH- induced GHR dimerization. Association of JAK2 with the GHR is enhanced by receptor dimerization.
Journal of Biological Chemistry.
274:33072-33084.
1999
|
|
1999
|
Developmental regulation of insulin-like growth factor-I and growth hormone receptor gene expression.
Molecular and Cellular Endocrinology.
152:125-136.
1999
|
|
1999
|
The angiotensin II-dependent association of Jak2 and c-Src requires the N-terminus of Jak2 and the SH2 domain of c-Src.
Circulation Research.
84:1332-1338.
1999
|
|
1999
|
Insulin inhibits growth hormone signaling via the growth hormone receptor/JAK2/STAT5B pathway.
Journal of Biological Chemistry.
274:13434-13442.
1999
|
|
1999
|
Growth hormone-mediated regulation of insulin-like growth factor I promoter activity in C6 glioma cells
1999
|
|
1999
|
Insulin receptor substrate-1 enhances growth hormone-induced proliferation
1999
|
|
1998
|
Growth hormone-dependent tyrosine phosphorylation of a GH receptor-associated high molecular weight protein immunologically related to JAK2.
Biochemical and Biophysical Research Communications.
253:774-779.
1998
|
|
1998
|
Involvement of the Src homology 2-containing tyrosine phosphatase SHP-2 in growth hormone signaling.
Journal of Biological Chemistry.
273:2344-2354.
1998
|
|
1998
|
Blockade of growth hormone receptor shedding by a metalloprotease inhibitor
1998
|
|
1997
|
Growth hormone induces detergent insolubility of GH receptors in IM-9 cells.
American Journal of Physiology.
273.
1997
|
|
1996
|
Growth hormone receptor cytoplasmic domain differentially promotes tyrosine phosphorylation of signal transducers and activators of transcription 5b and 3 by activated JAK2 kinase
1996
|
|
1995
|
The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor βc chain.
Journal of Biological Chemistry.
270:13814-13818.
1995
|
|
1995
|
Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor.
Journal of Biological Chemistry.
270:14776-14785.
1995
|
|
1994
|
Interaction of the growth hormone receptor cytoplasmic domain with the JAK2 tyrosine kinase
1994
|
|
1994
|
Treatment of IM-9 cells with human growth hormone (GH) promotes rapid disulfide linkage of the GH receptor
1994
|
|
1992
|
Erratum: Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production (Journal of Biological Chemistry (1992) 267 (13656-13660)).
Journal of Biological Chemistry.
267:19752.
1992
|
|
1992
|
Mutagenesis of T cell antigen receptor ζ chain tyrosine residues. Effects on tyrosine phosphorylation and lymphokine production.
Journal of Biological Chemistry.
267:13656-13660.
1992
|
|
1991
|
Localization of type I iodothyronine 5'-deiodinase to the basolateral plasma membrane in renal cortical epithelial cells.
Journal of Biological Chemistry.
266:11262-11269.
1991
|
|
1991
|
Structure/function analysis of the invariant subunits of the T cell antigen receptor.
Seminars in Immunology.
3:299-311.
1991
|
|
1990
|
The structure and signalling functions of the invariant T cell receptor components.
Seminars in Immunology.
2:89-97.
1990
|
|
1990
|
Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors.
Nature.
347:189-191.
1990
|
|
1990
|
Structural mutations of the T cell receptor ζ chain and its role in T cell activation.
Science.
249:174-177.
1990
|
|
1990
|
The diagnosis of acromegaly: Value of inferior petrosal sinus sampling.
American Journal of Roentgenology.
154:1075-1077.
1990
|
|
1989
|
Activation-driven programmed cell death and T cell receptor ζη expression.
Science.
246:1162-1165.
1989
|
|
1989
|
Biochemical characterization of the η chain of the T-cell receptor. A unique subunit related to ξ.
Journal of Biological Chemistry.
264:14812-14817.
1989
|
|
1989
|
Preoperative lateralization of pituitary microadenomas by petrosal sinus sampling: Utility in two patients with non-ACTH-secreting tumors.
American Journal of Medicine.
87:679-682.
1989
|
|
1989
|
Role of the zeta chain in the expression of the T cell antigen receptor: Genetic reconstitution studies
1989
|
|
1983
|
Differential sensitivity of brain iodothyronine 5'-deiodinases to sulfhydryl-blocking reagents.
Molecular and Cellular Endocrinology.
33:321-327.
1983
|
|