• Dr. Phillips received his undergraduate training in microbiology and environmental science at Alabama's Auburn University. Following this initial training, he worked as a genetics instructor at Birmingham-Southern College and a research assistant in UAB's department of cell biology. This work was soon followed with doctoral work at the University of North Carolina in Cell and Developmental Biology.

    Dr. Phillips quickly moved on to work as a research fellow at Vanderbilt University while also working as an adjunct professor at Sewanee University. He then began his work at UAB, directing the IDDRC Core B in the department of neurobiology before assuming the role of assistant professor in the neurobiology department, followed by a transition to the Rowe Lab in the UAB Cystic Fibrosis Research Center.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2018 Maternal smoking induces acquired CFTR dysfunction in neonatal ratsAmerican Journal of Respiratory and Critical Care Medicine.  198:672-674. 2018
    2018 Seeing cilia: Imaging modalities for ciliary motion and clinical connections 2018
    2016 Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory FunctionCell Reports.  16:2666-2685. 2016
    2016 Dynamic DNA methylation regulates neuronal intrinsic membrane excitabilityScience Signaling.  9. 2016
    2015 Ubiquitin-specific protease 14 regulates c-Jun N-terminal kinase signaling at the neuromuscular junctionMolecular Neurodegeneration.  10. 2015
    2015 DNA methylation regulates neuronal glutamatergic synaptic scalingScience Signaling.  8. 2015
    2015 Motor and Sensory Deficits in the teetering Mice Result from Mutation of the ESCRT Component HGSPLoS Genetics.  11. 2015
    2013 Genetic background alters the severity and onset of neuromuscular disease caused by the loss of ubiquitin-specific protease 14 (Usp14)PLoS ONE.  8. 2013
    2012 Usp14 Deficiency Increases Tau Phosphorylation without Altering Tau Degradation or Causing Tau-Dependent DeficitsPLoS ONE.  7. 2012
    2010 Erratum: Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjects (Clinical Pharmacology and Therapeutics (2007) 82 (579-585) doi:10.1038/sj.clpt.6100208)Clinical Pharmacology and Therapeutics.  88:138. 2010
    2007 The pathologies associated with functional titration of phosphatidylinositol transfer protein α activity in miceJournal of Lipid Research.  48:1857-1872. 2007
    2007 Conformational dynamics of the major yeast phosphatidylinositol transfer protein Sec14p: Insight into the mechanisms of phospholipid exchange and diseases of Sec14p-like protein deficiencies 2007
    2007 Cytochrome P450 3A5 genotype is associated with verapamil response in healthy subjectsClinical Pharmacology and Therapeutics.  82:579-585. 2007
    2006 Specific and nonspecific membrane-binding determinants cooperate in targeting phosphatidylinositol transfer protein β-isoform to the mammalian trans-Golgi network 2006
    2006 The diverse biological functions of phosphatidylinositol transfer proteins in eukaryotesCritical Reviews in Biochemistry and Molecular Biology.  41:21-49. 2006
    2005 Phosphatidylinositol transfer protein function in the yeast Saccharomyces cerevisiaeAdvances in Enzyme Regulation.  45:155-170. 2005
    2004 Phosphatidylinositol transfer protein function in the mouseAdvances in Enzyme Regulation.  44:201-218. 2004
    2003 Mice lacking phosphatidylinositol transfer protein-α exhibit spinocerebellar degeneration, intestinal and hepatic steatosis, and hypoglycemiaJournal of Biological Chemistry.  278:33501-33518. 2003
    2002 Genetic ablation of phosphatidylinositol transfer protein function in murine embryonic stem cells 2002
    2001 Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cellsBiochemical Journal.  356:287-296. 2001
    1999 Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivoMolecular Cell.  4:187-197. 1999
    1998 A phosphatidylinositol 3-kinase and phosphatidylinositol transfer protein act synergistically in formation of constitutive transport vesicles from the trans-Golgi networkJournal of Biological Chemistry.  273:10349-10354. 1998
    1998 Crystal structure of the Saccharomyces cerevisiae phosphatidylinositol- transfer proteinNature.  391:506-510. 1998
    1997 Essential role for diacylglycerol in protein transport from the yeast Golgi complexNature.  387:101-105. 1997
    1997 Crystallization and preliminary X-ray diffraction studies of the Saccharomyces cerevisiae phospholipid-transfer protein Sec14pActa Crystallographica Section D: Biological Crystallography.  53:784-786. 1997

    Teaching Overview

  • Dr. Phillips has worked at UAB as a lecturer for neuroscience in the Graduate Biomedical Science Program, at Birmingham-Southern College as an instructor for genetics, and at both Sewanee University and Vanderbilt University as an instructor for biology.
  • Education And Training

  • Doctor of Philosophy in Cell / Cellular and Molecular Biology, University of North Carolina System : Chapel Hill 2005
  • Full Name

  • Scott Phillips