Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 IGFBP6 controls the expansion of chemoresistant glioblastoma through paracrine IGF2/IGF-1R signaling 11 Medical and Health Sciences 1112 Oncology and Carcinogenesis 11 Medical and Health Sciences 1103 Clinical Sciences 2018
2018 Emerging role of circadian clock disruption in alcohol-induced liver disease 2018
2018 Genetic deletion of the circadian clock transcription factor BMAL1 and chronic alcohol consumption differentially alter hepatic glycogen in mice 2018
2018 Cellular abnormalities and emerging biomarkers in alcohol-associated liver disease 2018
2016 Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells 2016
2016 Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice 2016
2016 The methyl donor S-adenosylmethionine prevents liver hypoxia and dysregulation of mitochondrial bioenergetic function in a rat model of alcohol-induced fatty liver disease 2016
2016 Physiological processes underlying organ injury in alcohol abuse 2016
2016 Biotinylation: A novel posttranslational modification linking cell autonomous circadian clocks with metabolism 2016
2015 The molecular circadian clock and alcohol-induced liver injury 2015
2015 Chronic ethanol consumption disrupts diurnal rhythms of hepatic glycogen metabolism in mice 2015
2015 Inhalation Exposure Model of Hydrogen Sulfide (H2S)-Induced Hypometabolism in the Male Sprague-Dawley Rat 2015
2014 Proteomic analysis of 4-hydroxynonenal (4-HNE) modified proteins in liver mitochondria from chronic ethanol-fed rats 2014
2014 Mitochondrial-nuclear genome interactions in non-alcoholic fatty liver disease in mice 2014
2014 Involvement of the mitochondrial permeability transition pore in chronic ethanol-mediated liver injury in mice 2014
2014 Circadian regulation of metabolism 2014
2014 Ozone inhalation modifies the rat liver proteome 2014
2014 The Bioenergetic Health Index: a new concept in mitochondrial translational research. 2014
2013 Chronic Ethanol Consumption Disrupts the Core Molecular Clock and Diurnal Rhythms of Metabolic Genes in the Liver without Affecting the Suprachiasmatic Nucleus 2013
2013 Convergent mechanisms for dysregulation of mitochondrial quality control in metabolic disease: Implications for mitochondrial therapeutics 2013
2013 Redox biology of hydrogen sulfide: Implications for physiology, pathophysiology, and pharmacology 2013
2012 Reply to Haouzi and Van de Louw 2012
2012 Metabolic and cardiac signaling effects of inhaled hydrogen sulfide and low oxygen in male rats 2012
2012 Elucidating nature's solutions to heart, lung, and blood diseases and sleep disorders 2012
2012 Betaine treatment attenuates chronic ethanol-induced hepatic steatosis and alterations to the mitochondrial respiratory chain proteome. 2012
2011 Nitric oxide and hypoxia exacerbate alcohol-induced mitochondrial dysfunction in hepatocytes 2011
2011 Chronic exposure to a high-fat diet induces hepatic steatosis, impairs nitric oxide bioavailability, and modifies the mitochondrial proteome in mice 2011
2011 Emerging role of redox dysregulation in alcoholic and nonalcoholic fatty liver disease 2011
2010 Acquisition of temozolomide chemoresistance in gliomas leads to remodeling of mitochondrial electron transport chain 2010
2010 Chronic ethanol consumption enhances sensitivity to Ca2+- mediated opening of the mitochondrial permeability transition pore and increases cyclophilin D in liver 2010
2010 What part of NO don't you understand? Some answers to the cardinal questions in nitric oxide biology 2010
2010 Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: Novel molecular targets of disease and hepatoprotection 2010
2010 Assessment of mitochondrial dysfunction arising from treatment with hepatotoxicants 2010
2010 Advancing alcohol biomarkers research 2010
2010 Detection of protein thiols in mitochondrial oxidative phosphorylation complexes and associated proteins. 2010
2009 Ethanol and tobacco smoke increase hepatic steatosis and hypoxia in the hypercholesterolemic apoE-/- mouse: Implications for a "multihit" hypothesis of fatty liver disease 2009
2009 High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo 2009
2008 Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease. 2008
2008 Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases 2008
2008 Mitochondrial protein thiol modifications in acetaminophen hepatotoxicity: Effect on HMG-CoA synthase 2008
2008 Proteomic approaches to identify and characterize alterations to the mitochondrial proteome in alcoholic liver disease 2008
2007 Effect of alcohol and tobacco smoke on mtDNA damage and atherogenesis 2007
2007 Novel interactions of mitochondria and reactive oxygen/nitrogen species in alcohol mediated liver disease 2007
2006 S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver 2006
2006 Chronic ethanol consumption decreases mitochondrial and glycolytic production of ATP in liver 2006
2005 Nitroxia: The pathological consequence of dysfunction in the nitric oxide-cytochrome c oxidase signaling pathway 2005
2005 Mitochondrial proteomics in free radical research 2005
2004 The role of iNOS in alcohol-dependent hepatotoxicity and mitochondrial dysfunction in mice 2004
2004 Modification of the mitochondrial proteome in response to the stress of ethanol-dependent hepatotoxicity 2004
2004 Oxidative modification of hepatic mitochondria protein thiols: effect of chronic alcohol consumption. 2004
2004 Oxidative modification of hepatic mitochondria protein thiols: Effect of chronic alcohol consumption 2004
2003 Chronic alcohol consumption increases the sensitivity of rat liver mitochondrial respiration to inhibition by nitric oxide 2003
2003 A review of the role of reactive oxygen and nitrogen species in alcohol-induced mitochondrial dysfunction 2003
2002 Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: Studies using myxothiazol 2002
2002 Effects of alcohol and oxidative stress on liver pathology: The role of the mitochondrion 2002
2002 Contribution of mitochondria to oxidative stress associated with alcoholic liver disease 2002
2001 Ethanol consumption and liver mitochondria function 2001
2001 Ethanol and oxidative stress. 2001
2001 Chronic ethanol consumption alters the glutathione/glutathione peroxidase-1 system and protein oxidation status in rat liver 2001
2000 Effect of low flow ischemia-reperfusion injury on liver function 2000
2000 Antioxidants and gadolinium chloride attenuate hepatic parenchymal and endothelial cell injury induced by low flow ischemia and reperfusion in perfused rat livers 2000
1999 Ethanol stimulates the production of reactive oxygen species at mitochondrial complexes I and III 1999
1999 Effect of dietary fat on chronic ethanol-induced oxidative stress in hepatocytes 1999
1998 Acute and chronic ethanol increases reactive oxygen species generation and decreases viability in fresh, isolated rat hepatocytes 1998
1997 Comparison of salicylate and D-phenylalanine for detection of hydroxyl radicals in chemical and biological reactions 1997
1996 Potential antioxidant function of xanthine oxidase in low flow ischemia-reperfusion 1996
1994 Oxygen radical formation in well-washed rat liver microsomes: Spin trapping studies 1994

Chapter

Year Title Altmetric
2004 Role of Oxidative Stress in Alcohol-Induced Mitochondrial Dysfunction.  1153-1173. 2004

Teaching Activities

  • GBS707 - Basic Biochem/Metabolism (Fall Term 2019) 2019
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2018) 2018
  • GBS749 - Mitochondria (Spring Term 2018) 2018
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2017) 2017
  • GBS707 - Basic Biochem/Metabolism (Fall Term 2016) 2016
  • GBS749 - Special Topics Biomed Sci IV (Spring Term 2016) 2016
  • GBS749 - Special Topics Biomed Sci IV (Spring Term 2014) 2014
  • ENH799 - Dissertation Research (Fall Term 2012) 2012
  • ENH699 - Masters Level Project Res (Summer Term 2012) 2012
  • ENH799 - Dissertation Research (Summer Term 2012) 2012
  • ENH706 - Mitochondria Hlth DiseaseTox (Spring Term 2012) 2012
  • ENH799 - Dissertation Research (Spring Term 2012) 2012
  • ENH799 - Dissertation Research (Fall Term 2011) 2011
  • GBS704 - Intro to Experimental Med (Fall Term 2011) 2011
  • ENH799 - Dissertation Research (Summer Term 2011) 2011
  • ENH799 - Dissertation Research (Spring Term 2011) 2011
  • ENH799 - Dissertation Research (Fall Term 2010) 2010
  • ENH799 - Dissertation Research (Summer Term 2010) 2010
  • IBS706 - Mito Basis of Human Disease (Summer Term 2010) 2010
  • IBS798 - Non-Dissertation research (Summer Term 2010) 2010
  • ENH799 - Dissertation Research (Spring Term 2010) 2010
  • IBS701 - Pathophy/Pharmacology of Dis (Spring Term 2010) 2010
  • IBS798 - Non-Dissertation research (Spring Term 2010) 2010
  • ENH799 - Dissertation Research (Fall Term 2009) 2009
  • IBS798 - Non-Dissertation research (Fall Term 2009) 2009
  • ENH799 - Dissertation Research (Summer Term 2009) 2009
  • IBS706 - Mito Basis of Human Disease (Summer Term 2009) 2009
  • IBS798 - Non-Dissertation research (Summer Term 2009) 2009
  • ENH799 - Dissertation Research (Spring Term 2009) 2009
  • IBS701 - Pathophy/Pharmacology of Dis (Spring Term 2009) 2009
  • IBS798 - Non-Dissertation research (Spring Term 2009) 2009
  • ENH790 - Current Topics in ENH Res Sem (Fall Term 2008) 2008
  • ENH796 - Environ Hlth Sci Resrch (Fall Term 2008) 2008
  • ENH799 - Dissertation Research (Fall Term 2008) 2008
  • IBS798 - Non-Dissertation research (Fall Term 2008) 2008
  • ENH799 - Dissertation Research (Summer Term 2008) 2008
  • IBS706 - Mito Basis of Human Disease (Summer Term 2008) 2008
  • ENH790 - Current Topics in ENH Res Sem (Spring Term 2008) 2008
  • ENH798 - Doctoral Level Directed Res (Spring Term 2008) 2008
  • ENH790 - Current Topics in ENH Res Sem (Fall Term 2007) 2007
  • ENH798 - Doctoral Level Directed Res (Fall Term 2007) 2007
  • Education And Training

  • Wake Forest University School of Medicine Biochemistry, Postdoctoral Fellowship
  • Full Name

  • Shannon Bailey