The research interests of our laboratory are broadly in the areas of nutrition, health, obesity and longevity. We use primarily comparative aquatic animal models in studies related to human health. Our leading outcomes include understanding growth, reproduction, physiology and biochemistry, endocrinology, and immunological responses of aquatic models to nutritional and environmental stressors. We are particularly interested in those outcomes related to changes in body composition and the mechanisms therein as related to obesity and other comorbidities.
We are very interested in the zebrafish and sea urchin models for their value in biomedical research. Killifish models are also very important, particularly those of short-lived species and their use in aging research. We are also interested in nutrition as it relates to improving aquaculture of new species. The laboratory is committed to promoting issues related to sustainability.
The major topics of research in our laboratory include:
Understanding the effects of nutrition and the environment on the body composition and physiological function of aquatic organisms. Primary emphases involve mechanisms leading to or preventing obesity.
Developing standard reference and experimental diets for zebrafish Danio rerio, killifish Nothobranchius furzeri, and sea urchins (Lytechinus variegatus). These studies will lead us to understand the role of specific nutrients affecting development, growth, and health of parental and offspring populations.
Evaluating causative factors, including nutrition and environmental toxicants, affecting longevity in short-lived models.
Evaluating the nature and role of the microbiome in aquatic models, with emphasis in the response of the gut microbiome to nutrients and bioactive food components.
Using nanotechnologies to develop nutrient and drug delivery systems in aquatic animals.
Investigating the environmental physiology, growth, nutrition, and digestive physiology of species important in aquaculture, including sea urchins, tilapia, crayfish, penaeid shrimp, and freshwater prawns. Increased knowledge of these economically important organisms can lead to enhanced aquaculture practices.
Resource sustainability.
