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Saigusa, Takamitsu
Assistant Professor
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E-mail
tsaigusa@uabmc.edu
saigusa@uab.edu
Office Address
LHRB 621
LYONS-HARRISON RESEARCH BUILDING
Birmingham, AL 35294-0006
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Saigusa, Takamitsu
Assistant Professor
Positions
Associate Scientist (C)
,
Nephrology Research & Training Center
,
General Clinical Research Center
2016 -
Assistant Professor (P)
,
Medicine - Nephrology
,
Department of Medicine
2016 -
Assistant Professor (S)
,
Cell, Developmental and Integrative Biology (CDIB)
,
Academic Joint Departments
2018 -
Publications
Research
Background
Contact
Publications
Selected Publications
Academic Article
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Year
Title
Altmetric
2019
Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct
.
Journal of Youth and Adolescence
. 317:F632-F637.
2019
2018
Attenuation of accelerated renal cystogenesis in pkd1 mice by renin-angiotensin system blockade
.
Journal of Youth and Adolescence
. 314:F210-F218.
2018
2017
NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone
.
Current research in translational medicine
. 101:236-244.
2017
2016
Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model
.
Federation proceedings
. 30:370-379.
2016
2016
Suppressing kidney angiotensinogen in blood pressure regulation
.
Physiological Reports
. 4.
2016
2015
Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease
.
Physiological Reports
. 3.
2015
2015
Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage
.
Journal of Youth and Adolescence
. 309:F79-F87.
2015
2015
Molecular pathways and therapies in autosomal-dominant polycystic kidney disease
.
News in Physiological Sciences
. 30:195-207.
2015
2015
Reciprocal effect of angiotensin ii in collecting duct renin synthesis
.
Journal of Youth and Adolescence
. 309:F914-F915.
2015
2014
Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na
+
/H
+
exchanger
.
Life Science Alliance
. 307:C554-C560.
2014
2012
Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors
.
Journal of Youth and Adolescence
. 302.
2012
2009
Acute Massive Cerebral Infarctions Treated with Hemodialysis
.
Journal of Stroke and Cerebrovascular Diseases
. 18:316-318.
2009
2007
Effect of risedronate on high-dose corticosteroid-induced bone loss in patients with glomerular disease
.
Nephrology Dialysis Transplantation
. 22:1593-1600.
2007
2007
Involvement of transglutaminase-2 in pathological changes in renal disease
.
Nephron
. 105.
2007
2006
A case of essential thrombocytosis developing nephrotic syndrome and severe endothelial damage
.
Journal of Nephrology
. 19:656-659.
2006
2006
Impact of hypertension and hypertension-related vascular lesions in IgA nephropathy
.
Hypertension Research
. 29:15-22.
2006
2005
Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats
.
Nephrology Dialysis Transplantation
. 20:1573-1581.
2005
2004
Fractalkine and its receptor, CX3CR1, upregulation in streptozotocin- induced diabetic kidneys
.
Nephron
. 97.
2004
2004
Galectin-3-positive cell infiltration in human diabetic nephropathy
.
Nephrology Dialysis Transplantation
. 19:602-607.
2004
2002
Pathological analysis of renal diseases with mild proteinuria
.
Japanese Journal of Nephrology // Nihon Jinz¿ Gakkai
. 44:786-791.
2002
2002
Two cases of atherosclerotic renal artery stenosis treated by percutaneous transluminal renal angioplasty and intravascular stent placement, leading to improvement of hypertension and renal function
.
Japanese Journal of Nephrology // Nihon Jinz¿ Gakkai
. 44:102-108.
2002
2002
Two cases of atherosclerotic renal artery stenosis treated by percutaneous transluminal renal angioplasty and intravascular stent placement, leading to improvement of hypertension and renal function
.
Japanese Journal of Nephrology // Nihon Jinz¿ Gakkai
. Mar; 44:102-108.
2002
Research
Principal Investigator On
Kidney Specific Drug Delivery Using Nanoparticles in Pkd1 Mice
awarded by
PKD Foundation for Research in Polycystic Kidney Disease
2019 - 2021
The Role of Kidney Immune Cells in Acceleration of Cyst Growth
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
2019 - 2021
Renal Mechanism for Hypertension in Polycistic Kidney Disease
awarded by
National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS
2016 - 2020
Investigator On
Private Grant
awarded by
REATA PHARMACEUTICALS
2019 - 2024
Private Grant
awarded by
Sanofi US Services Inc
2019 - 2024
Background
Education And Training
Doctorate Level Degree in Medicine,
1998
Long Island College Hospital, Internship
2007
Long Island College Hospital, Residency
2009
Medical University of South Carolina, Postdoctoral Fellowship
2012
Contact
Full Name
Takamitsu
Saigusa