Positions

Selected Publications

Academic Article

Year Title Altmetric
2020 Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease. 2020
2019 Loss of primary cilia increases polycystin-2 and TRPV4 and the appearance of a nonselective cation channel in the mouse cortical collecting duct 2019
2018 Attenuation of accelerated renal cystogenesis in pkd1 mice by renin-angiotensin system blockade 2018
2017 NFAM1 signaling enhances osteoclast formation and bone resorption activity in Paget's disease of bone.  BONE.  101:236-244. 2017
2016 Suppressing angiotensinogen synthesis attenuates kidney cyst formation in a Pkd1 mouse model.  The FASEB Journal.  30:370-379. 2016
2016 Suppressing kidney angiotensinogen in blood pressure regulation.  Physiological Reports.  4. 2016
2015 Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.  Physiological Reports.  3. 2015
2015 Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage 2015
2015 Molecular pathways and therapies in autosomal-dominant polycystic kidney disease 2015
2015 Reciprocal effect of angiotensin ii in collecting duct renin synthesis 2015
2014 Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger 2014
2012 Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors 2012
2009 Acute Massive Cerebral Infarctions Treated with Hemodialysis.  Journal of Stroke and Cerebrovascular Diseases.  18:316-318. 2009
2007 Effect of risedronate on high-dose corticosteroid-induced bone loss in patients with glomerular disease.  Nephrology Dialysis Transplantation.  22:1593-1600. 2007
2007 Involvement of transglutaminase-2 in pathological changes in renal disease 2007
2006 A case of essential thrombocytosis developing nephrotic syndrome and severe endothelial damage.  Journal of Nephrology.  19:656-659. 2006
2006 Impact of hypertension and hypertension-related vascular lesions in IgA nephropathy.  Hypertension Research.  29:15-22. 2006
2005 Mizoribine reduces renal injury and macrophage infiltration in non-insulin-dependent diabetic rats.  Nephrology Dialysis Transplantation.  20:1573-1581. 2005
2004 Fractalkine and its receptor, CX3CR1, upregulation in streptozotocin- induced diabetic kidneys 2004
2004 Galectin-3-positive cell infiltration in human diabetic nephropathy.  Nephrology Dialysis Transplantation.  19:602-607. 2004
2002 Pathological analysis of renal diseases with mild proteinuria 2002
2002 Two cases of atherosclerotic renal artery stenosis treated by percutaneous transluminal renal angioplasty and intravascular stent placement, leading to improvement of hypertension and renal function 2002
2002 Two cases of atherosclerotic renal artery stenosis treated by percutaneous transluminal renal angioplasty and intravascular stent placement, leading to improvement of hypertension and renal function 2002

Education And Training

  • Doctorate Level Degree in Medicine, 1998
  • Long Island College Hospital, Internship 2007
  • Long Island College Hospital, Residency 2009
  • Medical University of South Carolina, Postdoctoral Fellowship 2012

    • Full Name

  • Takamitsu Saigusa