Selected Publications

Academic Article

Year Title Altmetric
2021 RAC1 nitration at Y32 IS involved in the endothelial barrier disruption associated with lipopolysaccharide-mediated acute lung injuryRedox Biology.  38. 2021
2020 Heme attenuates beta-endorphin levels in leukocytes of HIV positive individuals with chronic widespread painRedox Biology.  36. 2020
2020 Reactive species generated by heme impair alveolar epithelial sodium channel function in acute respiratory distress syndromeRedox Biology.  36. 2020
2020 Vascular permeability disruption explored in the proteomes of mouse lungs and human microvascular cells following acute bromine exposure 2020
2020 Vascular Endothelial Growth Factor-121 Administration Mitigates Halogen Inhalation-Induced Pulmonary Injury and Fetal Growth Restriction in Pregnant Mice 2020
2020 Chronic Pain in HIVMolecular Pain.  16. 2020
2019 Phosgene inhalation causes hemolysis and acute lung injuryToxicology Letters.  312:204-213. 2019
2018 Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysemaJCI insight.  3. 2018
2018 Can a Vitamin A day keep tuberculosis away?American Journal of Respiratory Cell and Molecular Biology.  59:523-524. 2018
2018 LPS-induced acute lung injury involves NF-kB–mediated downregulation of SOX18American Journal of Respiratory Cell and Molecular Biology.  58:614-624. 2018
2018 Exposure of neonatal mice to bromine impairs their alveolar development and lung function 2018
2017 Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant MiceHypertension.  70:390-400. 2017
2017 Hyper-activation of pp60Src limits nitric oxide signaling by increasing asymmetric dimethylarginine levels during acute lung injuryFree Radical Biology and Medicine.  102:217-228. 2017
2017 Role of apoptosis and autophagy in tuberculosis 2017
2016 Differential regulation of autophagy and mitophagy in pulmonary diseases 2016
2016 Redox regulation of epidermal growth factor receptor signaling during the development of pulmonary hypertension.Free Radical Biology and Medicine.  95:96-111. 2016
2016 Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung InjuryAntioxidants and Redox Signaling.  24:99-112. 2016
2016 Chlorine-induced cardiopulmonary injuryAnnals of the New York Academy of Sciences.  1374:159-167. 2016
2016 Role of heme in bromine-induced lung injuryAnnals of the New York Academy of Sciences.  1374:105-110. 2016
2015 Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infectionThe FASEB Journal.  29:2712-2725. 2015
2015 Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammationFree Radical Biology and Medicine.  85:83-94. 2015
2015 Endothelial nitric oxide synthase deficient mice are protected from lipopolysaccharide induced acute lung injury.PLoS ONE.  10:e0119918. 2015
2015 Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury 2015
2014 Sox18 preserves the pulmonary endothelial barrier under conditions of increased shear stress.Journal of Cellular Physiology.  229:1802-1816. 2014
2014 Nitration of tyrosine 247 inhibits protein kinase G-1α activity by attenuating cyclic guanosine monophosphate binding.Journal of Biological Chemistry.  289:7948-7961. 2014
2014 Dimethylarginine dimethylaminohydrolase II overexpression attenuates LPS-mediated lung leak in acute lung injury.American Journal of Respiratory Cell and Molecular Biology.  50:614-625. 2014
2014 Endothelin-1 stimulates catalase activity through the PKCδ-mediated phosphorylation of serine 167.Free Radical Biology and Medicine.  67:255-264. 2014
2014 PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.PLoS ONE.  9:e99823. 2014
2014 Protein engineering to develop a redox insensitive endothelial nitric oxide synthase.Redox Biology.  2:156-164. 2014
2013 Role of Carnitine Acetyl Transferase in Regulation of Nitric Oxide Signaling in Pulmonary Arterial Endothelial CellsInternational Journal of Molecular Sciences.  14:255-272. 2013
2012 Glutathione Supplementation Attenuates Lipopolysaccharide-Induced Mitochondrial Dysfunction and Apoptosis in a Mouse Model of Acute Lung InjuryFrontiers in Physiology.  3. 2012
2009 GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP 2009


Year Title Altmetric
2014 Endothelial dysfunction in acute lung injury.  27-49. 2014

Education And Training

  • Doctor of Philosophy in Vascular Surgery, Medical College of Georgia 2011
  • Doctor of Medicine, Odessa National Medical University 2002
  • Full Name

  • Saurabh Aggarwal