Positions

Selected Publications

Academic Article

Year Title Altmetric
2019 Phosgene inhalation causes hemolysis and acute lung injury 2019
2019 Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants 2019
2019 Bromine inhalation mimics ischemia-reperfusion Cardiomyocyte injury and Calpain activation in rats 2019
2019 Resveratrol and ivacaftor are additive G551D CFTR-channel potentiators: therapeutic implications for cystic fibrosis sinus disease 2019
2019 Role of fibroblast growth factor 23 and klotho cross talk in idiopathic pulmonary fibrosis 2019
2018 Heme scavenging reduces pulmonary endoplasmic reticulum stress, fibrosis, and emphysema 2018
2018 High molecular weight hyaluronan ameliorates allergic inflammation and airway hyperresponsiveness in the mouse 2018
2018 Influenza-mediated reduction of lung epithelial ion channel activity leads to dysregulated pulmonary fluid homeostasis 2018
2018 The common γ-chain cytokine IL-7 promotes immunopathogenesis during fungal asthma 2018
2018 Acidic mammalian chitinase negatively affects immune responses during acute and chronic Aspergillus fumigatus exposure 2018
2018 Halogen Inhalation-Induced Lung Injury and Acute Respiratory Distress Syndrome 2018
2018 Instillation of hyaluronan reverses acid instillation injury to the mammalian blood gas barrier 2018
2018 Systematic reviews of the literature: A better way of addressing basic science controversies 2018
2018 Therapeutic attenuation of the epithelial sodium channel with a SPLUNC1-derived peptide in airway diseases 2018
2018 Bromofatty aldehyde derived from bromine exposure and myeloperoxidase and eosinophil peroxidase modify GSH and protein 2018
2018 Exposure of neonatal mice to bromine impairs their alveolar development and lung function 2018
2018 In the shadow of giants: Challenges and opportunities for the new editor of physiological reviews 2018
2017 Influenza virus infection alters ion channel function of airway and alveolar cells: Mechanisms and physiological sequelae 2017
2017 Ion channels of the lung and their role in disease pathogenesis 2017
2017 Introducing Sadis Matalon, new editor-in-chief of physiological reviews 2017
2017 Mechanisms and Treatment of Halogen Inhalation-Induced Pulmonary and Systemic Injuries in Pregnant Mice 2017
2017 An official American Thoracic Society Workshop Report: Chemical inhalational disasters biology of lung injury, development of novel therapeutics, and medical preparedness 2017
2017 Measuring nitrate reductase activity from human and rodent tongues 2017
2017 Nitrite therapy prevents chlorine gas toxicity in rabbits 2017
2017 A novel role for primary cilia in airway remodeling 2017
2016 Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator 2016
2016 Formation of chlorinated lipids post-chlorine gas exposure 2016
2016 MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation 2016
2016 Mechanistic Approaches to Improve Correction of the Most Common Disease-Causing Mutation in Cystic Fibrosis 2016
2016 Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury 2016
2016 A synonymous codon change alters the drug sensitivity of ΔF508 cystic fibrosis transmembrane conductance regulator 2016
2016 Chlorine-induced cardiopulmonary injury 2016
2016 Role of heme in bromine-induced lung injury 2016
2015 Influenza virus M2 targets cystic fibrosis transmembrane conductance regulator for lysosomal degradation during viral infection 2015
2015 Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation 2015
2015 Chlorine inhalation-induced myocardial depression and failure 2015
2015 Heme oxygenase-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice 2015
2015 Hyaluronan mediates airway hyperresponsiveness in oxidative lung injury 2015
2015 Inhaled matters of the heart. 2015
2015 Respiratory syncytial virus infection increases chlorine-induced airway hyperresponsiveness 2015
2015 Role of epithelial sodium channels in the regulation of lung fluid homeostasis 2015
2014 Rescuing ΔF508 CFTR with trimethylangelicin, A dual-acting corrector and potentiator 2014
2014 Postexposure aerosolized heparin reduces lung injury in chlorine-exposed mice 2014
2014 Sinupret activates CFTR and TMEM16A-dependent transepithelial chloride transport and improves indicators of mucociliary clearance 2014
2014 TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury 2014
2014 Chlorine gas exposure disrupts nitric oxide homeostasis in the pulmonary vasculature 2014
2014 Nanoparticles and the lung: Friend or foe? 2014
2014 A critical review of the American journal of Physiology-Lung Cellular and Molecular Physiology: 2012–2015 2014
2014 CFTR and lung homeostasis 2014
2014 Inter-a-inhibitor blocks epithelial sodium channel activation and decreases nasal potential differences in DF508 mice 2014
2014 Nitrite therapy improves survival postexposure to chlorine gas 2014
2013 The silent codon change I507-ATC→ATT contributes to the severity of the AF508 CFTR channel dysfunction 2013
2013 Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption 2013
2013 Cigarette smoke and CFTR: Implications in the pathogenesis of COPD 2013
2013 Chlorine induces the unfolded protein response in murine lungs and skin 2013
2013 Chloride secretion across adult alveolar epithelial cells contributes to cardiogenic edema 2013
2013 Chlorine gas exposure increases susceptibility to invasive lung fungal infection 2013
2013 Defining lung injury in animals 2013
2013 Titanium oxide nanoparticle instillation induces inflammation and inhibits lung development in mice 2013
2013 Nano-TiO2 particles impair adhesion of airway epithelial cells to fibronectin 2013
2013 "Real-time visualization of lung function: From micro to macro" 2013
2013 Influenza matrix protein 2 alters CFTR expression and function through its ion channel activity 2013
2012 δ ENaC: A novel divergent amiloride-inhibitable sodium channel 2012
2012 Targeted aerosolized delivery of ascorbate in the lungs of chlorine-exposed rats 2012
2012 Administration of nitrite after chlorine gas exposure prevents lung injury: Effect of administration modality 2012
2012 The role of CFTR in transepithelial liquid transport in pig alveolar epithelia 2012
2012 Characterization of a novel splice variant of δ ENaC subunit in human lungs 2012
2012 The CFTR and ENaC debate: How important is ENaC in CF lung disease? 2012
2012 Post-exposure antioxidant treatment in rats decreases airway hyperplasia and hyperreactivity due to chlorine inhalation 2012
2012 Comparison of ribavirin and oseltamivir in reducing mortality and lung injury in mice infected with mouse adapted A/California/04/2009 (H1N1) 2012
2012 Assessment of locomotion in chlorine exposed mice by computer vision and neural networks 2012
2012 Regulation of alveolar epithelial Na + channels by ERK1/2 in chlorine-breathing mice 2012
2012 Participation of miR-200 in pulmonary fibrosis 2012
2012 The american journal of physiology lung cellular and molecular physiology: "the best place to publish basic, translational, and hypothesis-driven clinical lung research" 2012
2011 Constrictive bronchiolitis in soldiers [1] 2011
2011 Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung 2011
2011 Ascorbate and deferoxamine administration after chlorine exposure decrease mortality and lung injury in mice 2011
2011 Chlorine gas exposure causes systemic endothelial dysfunction by inhibiting endothelial nitric oxide synthase-dependent signaling 2011
2011 Postexposure administration of a β2-agonist decreases chlorine-induced airway hyperreactivity in mice 2011
2011 Dale J. Benos, Ph.D. (1950-2010) 2011
2011 Mitigation of chlorine gas lung injury in rats by postexposure administration of sodium nitrite 2011
2010 Elucidating mechanisms of chlorine toxicity: Reaction kinetics, thermodynamics, and physiological implications 2010
2010 Exposing animals to oxidant gases: Nose only vs. whole body 2010
2010 Mechanisms and modification of chlorine-induced lung injury in animals 2010
2010 Understanding and treating chlorine-induced lung injury 2010
2010 Myeloperoxidase-dependent inactivation of surfactant protein D in vitro and in vivo 2010
2010 Inhibition of lung fluid clearance and epithelial Na+ channels by chlorine, hypochlorous acid, and chloramines 2010
2010 Functional stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator in airway epithelial cells 2010
2010 Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in vivo 2010
2009 Highlights of the December issue 2009
2009 Reactive species and pulmonary edema 2009
2009 Influenza virus M2 protein inhibits epithelial sodium channels by increasing reactive oxygen species 2009
2009 Highlights of the October issue 2009
2009 α1-Antitrypsin inhibits epithelial Na+ transport in vitro and in vivo 2009
2009 Highlights of the August issue 2009
2009 Highlights of the July issue 2009
2009 Influenza exerts continued pressure in an era of modern medicine 2009
2009 Regulation of epithelial sodium channels by cGMP/PKGII 2009
2009 Inhibition of Na+ transport in lung epithelial cells by respiratory syncytial virus infection 2009
2009 Modification of surfactant protein D by reactive oxygen-nitrogen intermediates is accompanied by loss of aggregating activity, in vitro and in vivo 2009
2009 Regulation of nitrite transport in red blood cells by hemoglobin oxygen fractional saturation 2009
2009 Effect of phosphate salts concentrations, supporting electrolytes, and calcium phosphate salt precipitation on the pH of phosphate buffer solutions 2009
2009 Search and rescue finding ways to correct ΔF508 CFTR 2009
2009 Respiratory syncytial virus inhibits lung epithelial Na+ channels by up-regulating inducible nitric-oxide synthase 2009
2009 Highlights of the march issue 2009
2009 SARS-CoV proteins decrease levels and activity of human ENaC via activation of distinct PKC isoforms 2009
2008 α1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro 2008
2008 Mitigation of chlorine-induced lung injury by low-molecular-weight antioxidants 2008
2008 DETANO and nitrated lipids increase chloride secretion across lung airway cells 2008
2008 Enhanced cell-surface stability of rescued ΔF508 cystic fibrosis transmembrane conductance regulator (CFTR) by pharmacological chaperones 2008
2007 Modulation of alveolar fluid clearance by reactive oxygen-nitrogen intermediates 2007
2007 Post-infection A77-1726 blocks pathophysiologic sequelae of respiratory syncytial virus infection 2007
2007 Respiratory syncytial virus induces insensitivity to β-adrenergic agonists in mouse lung epithelium in vivo 2007
2007 Genomics and proteomics of lung disease: Conference summary 2007
2007 Adenosine regulation of alveolar fluid clearance 2007
2007 Surfactant dysfunction in SP-A-/- and iNOS-/- mice with mycoplasma infection 2007
2006 Interregulation of proton-gated Na+ channel 3 and cystic fibrosis transmembrane conductance regulator 2006
2006 Bactericidal function of alveolar macrophages in mechanically ventilated rabbits 2006
2006 Mechanisms of cystic fibrosis transmembrane conductance regulator activation by S-nitrosoglutathione 2006
2006 δ-subunit confers novel biophysical features to αβγ- human epithelial sodium channel (ENaC) via a physical interaction 2006
2006 Leflunomide prevents alveolar fluid clearance inhibition by respiratory syncytial virus 2006
2006 Upregulation of immunoproteasomes by nitric oxide: Potential antioxidative mechanism in endothelial cells 2006
2006 Reactive species mediate inhibition of alveolar type II sodium transport during mycoplasma infection 2006
2005 Thrombin increases lung water by decreasing Na,K-ATPase activity 2005
2005 American Journal of Respiratory Cell and Molecular Biology: Editors' notes 2005
2005 Apical trypsin increases ion transport and resistance by a phospholipase C-dependent rise of Ca2+ 2005
2005 Oleic acid damages ion transport promotes alveolar edema: The dark side of healthy living 2005
2004 Surfactant proteins and inflammation: The Yin and the Yang 2004
2004 Lipopolysaccharide increases alveolar type II cell number in fetal mouse lungs through Toll-like receptor 4 and NF-κB 2004
2004 Mutations in the extracellular loop of α-rENaC alter sensitivity to amiloride and reactive species 2004
2004 Regulation of amiloride-sensitive Na+ transport by basal nitric oxide 2004
2004 Upregulation of Alveolar Epithelial Active Na+ Transport Is Dependent on β2-Adrenergic Receptor Signaling 2004
2004 Role of Surfactant Protein-A in Nitric Oxide Production and Mycoplasma Killing in Congenic C57BL/6 Mice 2004
2004 Nucleotide-mediated inhibition of alveolar fluid clearance in BALB/c mice after respiratory syncytial virus infection 2004
2004 Regulation of Na+ channels in lung alveolar type II epithelial cells. 2004
2003 Novel SIN-1 reactive intermediates modulate chloride secretion across murine airway cells 2003
2003 cAMP-induced changes of apical membrane potentials of confluent H441 monolayers 2003
2003 Hyperoxia impairs antibacterial function of macrophages through effects on actin 2003
2003 Vectorial sodium transport across the mammalian alveolar epithelium: It occurs but through which cells? 2003
2003 Modulation of sodium transport in fetal alveolar epithelial cells by oxygen and corticosterone 2003
2002 Inhibition of human surfactant protein A function by oxidation intermediates of nitrite 2002
2002 Reactive oxygen nitrogen species decrease cystic fibrosis transmembrane conductance regulator expression and cAMP-mediated Cl- secretion in airway epithelia 2002
2002 Invited review: Biophysical properties of sodium channels in lung alveolar epithelial cells 2002
2002 Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-kappaB and MAPK/ERK mechanisms. 2002
2002 Alveolar macrophage activation after trauma-hemorrhage and sepsis is dependent on NF-κB and MAPK/ERK mechanisms 2002
2002 Elevated generation of reactive oxygen/nitrogen species in hantavirus cardiopulmonary syndrome 2002
2002 Effects of variable concentrations of inhaled nitric oxide and oxygen on the lungs of newborn piglets 2002
2002 Alveolar epithelial ion and fluid transport: Ca2+-dependent stimulation of alveolar fluid clearance in near-term fetal guinea pigs 2002
2002 Killing of Klebsiella pneumoniae by human alveolar macrophages 2002
2002 Enhancement of adenovirus-mediated gene transfer in lungs and epithelial cells by EGTA 2002
2002 The role of nitric oxide in lung innate immunity: Modulation by surfactant protein-A 2002
2002 cAMP regulation of Cl(-) and HCO(-)(3) secretion across rat fetal distal lung epithelial cells. 2002
2001 Chlorzoxazone or 1-EBIO increases Na+ absorption across cystic fibrosis airway epithelial cells 2001
2001 Reactive species in viral pneumonitis: Lessons from animal models 2001
2001 Cyclophosphamide decreases nitrotyrosine formation and inhibits nitric oxide production by alveolar macrophages in mycoplasmosis 2001
2001 Lack of amiloride-sensitive transport across alveolar and respiratory epithelium of iNOS(-/-) mice in vivo 2001
2001 Mechanisms of TNF-α stimulation of amiloride-sensitive sodium transport across alveolar epithelium 2001
2001 Mechanisms of TNF-alpha stimulation of amiloride-sensitive sodium transport across alveolar epithelium. 2001
2001 Increased levels of nitrate and surfactant protein A nitration in the pulmonary edema fluid of patients with acute lung injury 2001
2001 Modification of sodium transport and alveolar fluid clearance by hypoxia: Mechanisms and physiological implications 2001
2001 Na,K-ATPase gene transfer mitigates an oxidant-induced decrease of active sodium transport in rat fetal ATII cells 2001
2001 Nitric oxide and nitrotyrosine in the lungs of patients with acute respiratory distress syndrome 2001
2000 Guanylyl cyclase stimulatory coupling to K(Ca) channels 2000
2000 Modification of biophysical properties of lung epithelial Na+ channels by dexamethasone 2000
2000 Carbon dioxide enhances nitration of surfactant protein A by activated alveolar macrophages 2000
2000 Biophysical properties and molecular characterization of amiloride- sensitive sodium channels in A549 cells 2000
2000 Mechanisms of increased Na+ transport in ATII cells by cAMP: We agree to disagree and do more experiments 2000
2000 Cyclophosphamide prevents systemic keratinocyte growth factor-induced up-regulation of surfactant protein A after allogeneic transplant in mice 2000
2000 DETANONOate, a nitric oxide donor, decreases amiloride-sensitive alveolar fluid clearance in rabbits 2000
2000 Halothane does not decrease amiloride-sensitive alveolar fluid clearance in rabbits 2000
2000 Protein nitration, metabolites of reactive nitrogen species, and inflammation in lung allografts 2000
1999 Chapter 13 Inhibition of Vectorial Na+ Transport across Alveolar Epithelial Cells by Nitrogen-Oxygen Reactive Species 1999
1999 Oxidant-mediated lung injury in the acute respiratory distress syndrome 1999
1999 Nitric oxide inhibits heterologous CFTR expression in polarized epithelial cells 1999
1999 Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation 1999
1999 Extreme, progressive isovolemic hemodilution with 5% human albumin, pentalyte, or hextend does not cause hepatic ischemia or histologic injury in rabbits 1999
1999 Surfactant protein a mediates mycoplasmacidal activity of alveolar macrophages by production of peroxynitrite 1999
1999 Sodium channels in alveolar epithelial cells: Molecular characterization, biophysical properties, and physiological significance 1999
1999 Surfactant protein B deficiency worsens hyperoxic injury to the alveolar epithelium 1999
1998 Hydrogen peroxide inhibits cAMP-induced Cl- secretion across colonic epithelial cells 1998
1998 Nitrated SP-A does not enhance adherence of Pneumocystis carinii to alveolar macrophages 1998
1998 Nitrated SP-A does not enhance adherence of Pneumocystis carinii to alveolar macrophages 1998
1998 cAMP activation of chloride and fluid secretion across the rabbit alveolar epithelium 1998
1998 Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the rat 1998
1998 Peroxynitrite inhibits amiloride-sensitive Na+ currents in Xenopus oocytes expressing alpha beta gamma-rENaC. 1998
1998 Peroxynitrite inhibits amiloride-sensitive Na+ currents in Xenopus oocytes expressing αβγ-rENaC 1998
1998 Surfactant protein A mediates mycoplasmacidal activity of alveolar macrophages 1998
1998 Mechanisms of mycoplasmal killing by alveolar macrophages in vitro 1998
1998 Nitric oxide inhibits Na+ absorption across cultured alveolar type II monolayers 1998
1998 Nitric oxide inhibits Na+ absorption across cultured alveolar type II monolayers 1998
1998 Modulation of rat lung Na+,K+-ATPase gene expression by hyperoxia 1998
1997 Peroxynitrite (ONOO-) inhibits Na+ channel activity in xenopus oocytes expressing αβγ-rENaC 1997
1997 Protein kinase a phosphorylation and G-protein regulation of type II pneumocyte Na+ channels 1997
1997 Differential induction of c-fos, c-jun, and apoptosis in lung epithelial cells exposed to ROS or RNS 1997
1997 Exosurf enhances adenovirus-mediated gene transfer to alveolar type II cells 1997
1997 Inhibition of surfactant function by copper-zinc superoxide dismutase (CuZn-SOD) 1997
1997 Protein kinase A phosphorylation and G protein regulation of type II pneumocyte Na+ channels in lipid bilayers 1997
1997 Mechanisms and sequelae of increased alveolar fluid clearance in hyperoxic rats 1997
1997 Modulation of Adenovirus-mediated Gene Transfer by Nitric Oxide 1997
1997 The interplay of nitric oxide and peroxynitrite with signal transduction pathways: Implications for disease 1997
1996 Biophysical and molecular properties of amilorideinhibitable Na+ channels in alveolar epithelial cells 1996
1996 Prolonged exposure to hjoj inhibits active ion transport across T84 cells 1996
1996 Sublethal hyperoxia increase lung fluid clearance in rats 1996
1996 Identification of nitration sites on surfactant protein A by tandem electrospray mass spectrometry 1996
1996 Biophysical and molecular properties of amiloride-inhibitable Na+ channels in alveolar epithelial cells 1996
1996 Nitration of surfactant protein A (SP-A) tyrosine residues results in decreased mannose binding ability 1996
1996 Inhibition of alveolar type II cell ATP and surfactant synthesis by nitric oxide 1996
1996 Clinical surfactant preparations mediate SOD and catalase uptake by type II cells and lung tissue 1996
1996 Inhaled nitric oxide injures the pulmonary surfactant system of lambs in vivo 1996
1996 Nitration of surfactant protein A results in decreased ability to aggregate lipids 1996
1996 Adult alveolar type II cells lack cAMP and Ca2+-activated Cl- channels 1996
1996 Na+-K+-ATPan mRNA expression in rat lung during adaptive and lethal hyperoxia 1996
1996 Quantitation of the Alveolar Distribution of Surfactant Mixtures in Normal and Injured Lungs 1996
1995 Cationic lipids for reporter gene and CFTR transfer to rat pulmonary epithelium 1995
1995 Increased expression and activity of sodium channels in alveolar type II cells of hyperoxic rats 1995
1995 Reconstitution of immunopurified alveolar type II cell Na+ channel protein into planar lipid bilayers 1995
1995 Hyperoxic lung injury reduces exogenous surfactant clearance in vivo 1995
1995 Interaction of surfactant mixtures with reactive oxygen and nitrogen species 1995
1995 Liver ischemia-reperfusion increases pulmonary permeability in rat: Role of circulating xanthine oxidase 1995
1995 Regulation of fluid-phase endocytosis in alveolar macrophages 1995
1994 Informed consent to participate in a research study 1994
1994 Gene Therapy for Cystic Fibrosis Using Cationic Liposome Mediated Gene Transfer: A Phase I Trial of Safety and Efficacy in the Nasal Airway. 1994
1994 Informed consent to participate in a research study -- gene therapy for cystic fibrosis using cationic liposome mediated gene transfer: a phase I trial of safety and efficacy in the nasal airway. 1994
1994 Regulation of low-amiloride-affinity sodium channels in alveolar type II cells 1994
1994 Regulation of low-amiloride-affinity sodium channels in alveolar type II cells 1994
1994 Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells 1994
1994 Upregulation of sodium conductive pathways in alveolar type II cells in sublethal hyperoxia 1994
1994 Concurrent generation of nitric oxide and superoxide damages surfactant protein A 1994
1994 Concurrent generation of nitric oxide and superoxide damages surfactant protein A 1994
1994 Dependence of surfactant function on extracellular pH: Mechanisms and modifications 1994
1994 Invited editorial on 'natural surfactant and hyperoxic lung injury in primates' 1994
1994 Manganese superoxide dismutase expression in alveolar type II epithelial cells from nonventilated and hypoperfused lungs. 1994
1994 Peroxynitrite inhibition of oxygen consumption and sodium transport in alveolar type II cells 1994
1994 Quantitation of nitrotyrosine levels in lung sections of patients and animals with acute lung injury 1994
1994 Upregulation of sodium conductive pathways in alveolar type II cells in sublethal hyperoxia 1994
1993 Mechanisms of peroxynitrite-induced injury to pulmonary surfactants 1993
1993 Mechanisms of peroxynitrite-induced injury to pulmonary surfactants 1993
1993 Fetal lung epithelial cells contain two populations of amiloride-sensitive Na+ channels 1993
1993 Culture-induced alterations in alveolar type II cell Na+ conductance. 1993
1993 Mitigation of oxidant injury to lung microvasculature by intratracheal instillation of antioxidant enzymes 1993
1993 Oxidant injury to the alveolar epithelium: biochemical and pharmacologic studies. 1993
1992 Erratum: Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes (The Journal of Biological Chemistry (1992) 267 (18498-18504)) 1992
1992 Quantitation of alveolar distribution of liposome-entrapped antioxidant enzymes. 1992
1992 Biochemical evidence for the presence of an amiloride binding protein in adult alveolar type II pneumocytes 1992
1992 Immunocytochemical and functional characterization of Na+ conductance in adult alveolar pneumocytes. 1992
1992 Peroxynitrite inhibits sodium uptake in rat colonic membrane vesicles 1992
1992 Immunocytochemical and functional characterization of Na+ conductance in adult alveolar pneumocytes 1992
1992 Mechanisms of extracellular reactive oxygen species injury to the pulmonary microvasculature 1992
1992 Quantitation of alveolar distribution of liposome-entrapped antioxidant enzymes 1992
1991 Mechanisms and regulation of ion transport in adult mammalian alveolar type II pneumocytes 1991
1991 Mechanisms of H2O2-mediated injury to type II cell surfactant metabolism and protection with PEG-catalase 1991
1991 Amiloride-inhibitable Na+ conductive pathways in alveolar type II pneumocytes 1991
1990 Mechanisms of extracellular hydrogen peroxide clearance by alveolar type II pneumocytes 1990
1990 Quantitative ultrastructural study of the rabbit lung: Exposure to 60% oxygen for 21 days 1990
1990 Characterization of antioxidant activities of pulmonary surfactant mixtures 1990
1990 Endogenous xanthine oxidase-derived O2 metabolites inhibit surfactant metabolism 1990
1989 Role of pulmonary surfactant in the development and treatment of adult respiratory distress syndrome 1989
1989 Tumor necrosis factor and interleukin 1α increase vascular endothelial permeability 1989
1989 Alveolar hyperoxic injury in rabbits receiving exogenous surfactant 1989
1989 Development of O2 tolerance in rabbits with no increase in antioxidant enzymes 1989
1989 Oxidant inhibition of epithelial active sodium transport 1989
1989 Responses of type II pneumocyte antioxidant enzymes to normoxic and hyperoxic culture 1989
1989 Surfactant replacement attenuates the increase in alveolar permeability in hyperoxia 1989
1988 Type II pneumocyte changes during hyperoxic lung injury and recovery 1988
1988 Sublethal hyperoxic injury to the alveolar epithelium and the pulmonary surfactant system 1988
1987 Alveolar epithelial changes in rabbits after a 21-day exposure to 60% O2 1987
1987 Mitigation of pulmonary hyperoxic injury by administration of exogenous surfactant 1987
1986 Reversibility of oxygen-induced injury to the alveolar epithelium: An ultrastructural study 1986
1986 Effects of hyperoxia on alveolar permeability of neutropenic rabbits 1986
1986 Intravenous bleomycin does not alter the toxic effects of hyperoxia in rabbits 1986
1985 Modification of pulmonary oxygen toxicity by bleomycin treatment 1985
1985 Pulmonary physiological and surfactant changes during injury and recovery from hyperoxia 1985
1985 Effects of 100% oxygen breathing on the capillary filtration coefficient in rabbit lungs 1985
1985 Peripheral circulatory responses to 96 hours of eucapnic hypoxia in conscious sheep 1985
1984 Interstitial fluid volumes and albumin spaces in pulmonary oxygen toxicity 1984
1984 Changes in lung mechanics and bronchoalveolar lavage following exposure to 100% O2 1984
1984 Effects of 100% O2 breathing on albumin extravascular spaces and permeability surface area products 1984
1984 Peripheral circulatory response to chronic eucapnic hypoxia in conscious sheep 1984
1984 Regional circulatory responses to 96 hours of hypoxia in conscious sheep 1984
1983 Cardiac output and regional oxygen transport in the acutely hypoxic conscious sheep 1983
1983 Effects of acute hypercapnia on the central and peripheral circulation of conscious sheep 1983
1982 Effects of hyperventilation on pulmonary blood flow and recirculation time of humans 1982
1982 Pulmonary and circulatory changes in conscious sheep exposed to 100% O2 at 1 ATA 1982
1981 An ultrastructural study of alveolar permeability to cytochrome C in the rabbit lung. Effect of exposure to 100% oxygen at one atmosphere 1981
1981 Effects of 100% O2breathing on permeability of alveolar epithelium to solute 1981
1980 Ventilation-perfusion lines and gas exchange in liquid breathing: Theory 1980
1979 Cardiopulmonary readjustments in passive tilt 1979

Book

Year Title Altmetric
2008 Chapter 3 Modulation of Lung Epithelial Sodium Channel Function by Nitric Oxide.  Ed. 61.  2008
2008 Preface.  Ed. 61.  2008

Chapter

Year Title Altmetric
2015 Regulation of Airway Lining Fluid in Health and Disease.  467-477. 2015
2006 Surfactant Protein A (SP-A).  143-148. 2006
2005 Epithelial sodium channel function in health and disease in the adult lung.  185-198. 2005
2005 Roles of reactive oxygen and nitrogen species in lung injury.  227-268. 2005
2005 Surfactant activity and dysfunction in lung injury.  297-352. 2005
2003 Resolution of alveolar edema: Mechanisms and relationship to clinical acute lung injury.  357-380. 2003
2002 Role of reactive oxygen and nitrogen species in lung injury.  159-195. 2002
1999 Mechanisms and physiological sequelae of reactive species injury to the alveolar epithelium.  431-456. 1999

Principal Investigator On

  • CIALIS® Reverses Halogen Induced Injury to Pregnant Animals and Their Offspring  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2016 - 2021
  • Bromine Inhalation Induced Lung Injury: Novel Mechanisms and Treatment Strategies  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2020
  • Private Grant  awarded by HEART BIOTECH HOLDINGS, LLC 2015 - 2017
  • Mechanisms and Countermeasures of Halogen-Induced Injury to Pregnant Mice  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2015 - 2016
  • Central Role of Heme Oxygenase in Reversing Bromine Morbidity and Mortality  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2014 - 2016
  • Low Molecular Weight Hyaluronan Mediated Inflammation and Airway Hyperresponsive in Aspiration Induced Acute Lung Injury  awarded by Foundation for Anesthesia Education & Research 2015 - 2016
  • Targeting Injury Pathways to Counteract Pulmonary Agent and Vesicant Toxicity  awarded by Yale University 2011 - 2016
  • Accelerating Inflammation Resolution to Counteract Chemical Injury  awarded by Duke University 2014 - 2015
  • Mitochondrial Bioenergetic Dysfunction and Chlorine Toxicity  awarded by National Institute of Neurological Disorders and Stroke/NIH/DHHS 2013 - 2015
  • Private Grant  awarded by GlaxoSmithKline 2013 - 2014
  • Mechanisms of ENaC Inhibition by Replicating Influenza Virus: Role of M2 Protein  awarded by National Heart, Lung, and Blood Institute/NIH/DHHS 2009 - 2014
  • Accelerating Inflammation Resolution to CounterACT Chemical Injury  awarded by Yale University 2012 - 2014
  • Novel Treatments of Chlorine Induced Injury to the Cardio-Respiratory Systems  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2008 - 2012
  • Prevention and Treatment of Chlorine Gas Induced Injury to the Pulmonary System  awarded by National Institute of Environmental Health Sciences/NIH/DHHS 2006 - 2012
  • Nanoparticle Induced Injury to Adult and Developing Lungs  awarded by Department of Commerce 2009 - 2011
  • Full Name

  • Sadis Matalon