Positions

Selected Publications

Academic Article

Year Title Altmetric
2022 Right Lobe Versus Left Lobe Living Donor Liver Transplantation: A Systematic Review and Meta-analysis of Donor and Recipient OutcomesTransplantation.  106:2370-2378. 2022
2022 Incidence and Mortality of Emergency General Surgery Conditions Among Solid Organ Transplant Recipients in Ontario, Canada: A Population-based Analysis.Transplantation2022
2021 Comment on "long-term Outcome of Surgery Versus Conservative Management for Recurrent and Ongoing Complaints after an Episode of Diverticulitis": Statistically Significant Results Are Not Necessarily Clinically ImportantAnnals of Surgery.  274:E680-E681. 2021
2021 Improving the reporting of non-inferiority trials by incorporating non-efficacy benefits: not all non-inferiority trials are created equalEuropean Journal of Epidemiology.  36:1097-1101. 2021
2021 Long-term Outcomes of Laparoscopic Lavage for Perforated Diverticulitis Remain UnfavorableJAMA Surgery.  156:1070-1071. 2021
2021 Outcomes of highly selected live donors with a future liver remnant less than or equal to 30%: A matched cohort studyTransplantation.  105:2397-2403. 2021
2021 Comments and Concerns on the LASER TrialJAMA Surgery.  156:985-986. 2021
2021 Use of the small-bites fascial closure technique and strategies to improve adoption: mixed-methods study 2021
2021 Association of perioperative red blood cell transfusions with all-cause and cancer-specific death in patients undergoing surgery for gastrointestinal cancer: Long-term outcomes from a population-based cohortSurgery.  170:870-879. 2021
2021 Long-term outcomes of resection for locoregional recurrence of colon cancer: A retrospective descriptive cohort study 2021
2021 Pregnancy after heart transplantation: A second-generation transmission of the gift of life—in replyJournal of Heart and Lung Transplantation.  40:235. 2021
2021 Optimizing opioid prescriptions after laparoscopic appendectomy and cholecystectomyCanadian Journal of Surgery.  64:E69-E75. 2021
2020 Meta-analysis of noninferiority and equivalence trials: ignoring trial design leads to differing and possibly misleading conclusionsJournal of Clinical Epidemiology.  127:134-141. 2020
2020 Comparing Observation, Axillary Radiotherapy, and Completion Axillary Lymph Node Dissection for Management of Axilla in Breast Cancer in Patients with Positive Sentinel Nodes: A Systematic ReviewAnnals of Surgical Oncology.  27:2664-2676. 2020
2020 Early urinary catheter removal after rectal surgery: systematic review and meta-analysisBJS Open.  4:545-553. 2020
2020 Optimal Operative Strategy for Hinchey III Sigmoid Diverticulitis: A Decision AnalysisDiseases of the Colon and Rectum.  63:1108-1117. 2020
2020 Does oncoplastic surgery increase immediate (30-day) postoperative complications? An analysis of the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) databaseBreast Cancer Research and Treatment.  182:429-438. 2020
2020 Local excision after preoperative chemoradiation for T2 and T3 rectal cancers: is the wait over?Lancet Gastroenterology and Hepatology.  5:422-424. 2020
2020 Propofol versus midazolam with or without short-acting opioids for sedation in colonoscopy: a systematic review and meta-analysis of safety, satisfaction, and efficiency outcomesGastrointestinal Endoscopy.  91:1015-1026.e7. 2020
2020 Pregnancy outcomes in women with cardiothoracic transplants: A Systematic review and meta-analysisJournal of Heart and Lung Transplantation.  39:93-102. 2020
2019 Using Patient Preferences to Determine Noninferiority Margins in Trials - ReplyJournal of the American Medical Association.  322:2138. 2019
2019 ASO Author Reflections: Clarifying the Controversy Generated by Non-inferiority Trials of Laparoscopic Surgery for Rectal CancerAnnals of Surgical Oncology.  26:545-546. 2019
2019 Do North American colorectal surgeons use mesh to prevent parastomal hernia? A survey of current attitudes and practiceCanadian Journal of Surgery.  62:426-435. 2019
2019 Response to comment on “routine use of laparoscopic surgery for rectal cancer”Annals of Surgery.  270:e146-e147. 2019
2019 Laparoscopic and robotic hysterectomy in endometrial cancer patients with obesity: a systematic review and meta-analysis of conversions and complicationsAmerican Journal of Obstetrics and Gynecology.  221:410-428.e19. 2019
2019 A note on competing risks in analyses of cancer-specific mortalityInternational Journal of Cancer.  145:1704-1705. 2019
2019 The end of the Hartmann's era for perforated diverticulitisLancet Gastroenterology and Hepatology.  4:573-575. 2019
2019 The Fragility Index - P Values Reimagined, Flaws and AllJAMA Surgery.  154:674. 2019
2019 Laparoscopic Versus Open Resection for Rectal Cancer: A Noninferiority Meta-analysis of Quality of Surgical Resection OutcomesAnnals of Surgery.  269:849-855. 2019
2019 Unifying Design and Analysis for Superiority and Noninferiority Trials with Appropriate End Point - ReplyJAMA Surgery.  154:467-468. 2019
2019 Comparison of Radioactive Seed Localized Excision and Wire Localized Excision of Breast Lesions: A Community Hospital's ExperienceClinical Breast Cancer.  19:e364-e369. 2019
2019 Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trialsOncoImmunology.  8. 2019
2019 Frequency of Misinterpretation of Inconclusive Noninferiority Trials: The Case of the Laparoscopic vs Open Resection for Rectal Cancer TrialsJAMA Surgery.  154:90-92. 2019
2018 Defining Non-inferiority Margins for Quality of Surgical Resection for Rectal Cancer: A Delphi Consensus StudyAnnals of Surgical Oncology.  25:3171-3178. 2018
2018 Etiology of increased cancer incidence after solid organ transplantationTransplantation Reviews.  32:218-224. 2018
2018 Intra-arterial therapies for unresectable and chemorefractory colorectal cancer liver metastases: a systematic review and meta-analysis 2018
2018 Association between adjuvant chemotherapy and overall survival in patients with rectal cancer and pathological complete response after neoadjuvant chemotherapy and resectionJAMA Oncology.  4:930-937. 2018
2018 Management of positive margins after initial lumpectomy in elderly women with breast cancer 2018
2018 Solid Organ Transplantation in Patients with Preexisting Malignancies in Remission: A Propensity Score Matched Cohort StudyTransplantation.  102:1156-1164. 2018
2018 Thirty-day postoperative morbidity and mortality in elderly women with breast cancer: an analysis of the NSQIP databaseBreast Cancer Research and Treatment.  170:373-379. 2018
2018 Opioid Use after Discharge in Postoperative Patients: A Systematic ReviewAnnals of Surgery.  267:1056-1062. 2018
2018 Health State Utility Values for Ileostomies and Colostomies: a Systematic Review and Meta-AnalysisJournal of Gastrointestinal Surgery.  22:894-905. 2018
2018 Chest Wall Resection for Recurrent Breast Cancer in the Modern EraAnnals of Surgery.  267:646-655. 2018
2018 Cancer evaluation in the assessment of solid organ transplant candidates: A systematic review of clinical practice guidelinesTransplantation Reviews.  32:29-35. 2018
2018 Harmful or physiologic: Diagnosing fibrinolysis shutdown in a trauma cohort with rotational thromboelastometryAnesthesia and Analgesia.  127:840-849. 2018
2018 Operative strategies for perforated diverticulitis: A Systematic Review and Meta-analysisDiseases of the Colon and Rectum.  61:1442-1453. 2018
2017 Cancer recurrence after solid organ transplantation: A systematic review and meta-analysisTransplantation Reviews.  31:240-248. 2017
2017 Pathologic outcomes of laparoscopic vs open mesorectal excision for rectal cancer(1)JAMA Surgery.  152:986-987. 2017
2017 Incidence and identification of risk factors for trastuzumab-induced cardiotoxicity in breast cancer patients: an audit of a single “real-world” settingMedical Oncology.  34. 2017
2017 Uptake of Cancer Screening Tests Among Recipients of Solid Organ TransplantationAmerican Journal of Transplantation.  17:2434-2443. 2017
2017 A watch-and-wait approach for locally advanced rectal cancer after a clinical complete response following neoadjuvant chemoradiation: a systematic review and meta-analysisLancet Gastroenterology and Hepatology.  2:501-513. 2017
2017 Surgery Versus Chemotherapy and Radiotherapy For Early and Locally Advanced Small Cell Lung Cancer: A Propensity-Matched Analysis of SurvivalLung Cancer.  109:78-88. 2017
2017 Preoperative localization of colorectal cancer: a systematic review and meta-analysis 2017
2017 Tamoxifen with radiotherapy compared with Tamoxifen alone in elderly women with early-stage breast cancer treated with breast conserving surgery: A systematic review and meta-analysisRadiotherapy and Oncology.  123:1-9. 2017
2017 Cancer Screening Recommendations for Solid Organ Transplant Recipients: A Systematic Review of Clinical Practice GuidelinesAmerican Journal of Transplantation.  17:103-114. 2017
2017 Oncologic Outcomes Following Laparoscopic versus Open Resection of pT4 Colon Cancer: A Systematic Review and Meta-analysisDiseases of the Colon and Rectum.  60:116-125. 2017
2017 Outcomes of solid organ transplant recipients with preexisting malignancies in remission: A systematic review and meta-analysisTransplantation.  101:471-481. 2017
2017 Thrombocytosis in splenic trauma: In-hospital course and association with venous thromboembolism 2017
2016 Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies 2016
2016 Outcomes of resection for locoregionally recurrent colon cancer: A systematic reviewSurgery.  160:54-66. 2016
2016 Cancer mortality among recipients of solid-organ transplantation in Ontario, CanadaJAMA Oncology.  2:463-469. 2016
2015 Oncolytic vaccinia virus synergizes with irinotecan in colorectal cancerMolecular Oncology.  9:1539-1552. 2015
2015 Do elderly patients have the most to gain from laparoscopic surgery?Annals of medicine and surgery (2012).  4:321-323. 2015
2015 Complement inhibition prevents oncolytic vaccinia virus neutralization in immune humans and cynomolgus macaquesMolecular Therapy.  23:1066-1076. 2015
2015 Incorporating smartphones into clinical practiceAnnals of medicine and surgery (2012).  4:187-188. 2015
2014 Tumor vascularization is critical for oncolytic vaccinia virus treatment of peritoneal carcinomatosisInternational Journal of Cancer.  134:717-730. 2014
2014 Assessing patterns of practice of sentinel lymph node biopsy for breast cancer in Latin AmericaWorld Journal of Surgery.  38:1077-1083. 2014
2014 Bilateral necrotizing fasciitis of the breast following quadrantectomyBreast Cancer.  21:108-114. 2014
2014 Oncolytic vaccinia virus as an adjuvant treatment to cytoreductive surgery for malignant peritoneal mesotheliomaAnnals of Surgical Oncology.  21:2259-2266. 2014
2013 Mounting a strategic offense: Fighting tumor vasculature with oncolytic virusesTrends in Molecular Medicine.  19:378-392. 2013
2013 Quality indicators for sentinel lymph node biopsy: Is there room for improvement?Canadian Journal of Surgery.  56:82-88. 2013
2012 Meeting surgical necessities for sentinel lymph node biopsy in breast cancer: Experience with methylene blue in a colombian hospital 2012
2012 Determining the use of prophylactic antibiotics in breast cancer surgeries: A survey of practiceBMC Surgery.  12. 2012
2011 Perioperative variables associated with surgical site infection in breast cancer surgeryJournal of Hospital Infection.  79:328-332. 2011

Education And Training

  • University of Toronto, Postdoctoral Research
  • University of Toronto, Residency
  • Doctor of Medicine, Pontifical Bolivariana University 2009
  • Full Name

  • Sergio Acuna Mancilla