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Robert Hardy Ph.D.
Professor Emeritus
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rwfh1@uab.edu
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Robert Hardy Ph.D.
Professor Emeritus
Positions
Professor - Emeritus (P)
,
Laboratory Medicine
,
Clinical Pathology
Publications
Research
Teaching
Background
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Publications
Selected Publications
Academic Article
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Year
Title
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2014
Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice
.
PLoS ONE
. 9.
2014
2014
Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis
.
Clinical and Experimental Metastasis
. 31:625-638.
2014
2014
The Bioenergetic Health Index: a new concept in mitochondrial translational research.
.
Clinical Science
. 127:367-373.
2014
2013
Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood
.
Laboratory Investigation
. 93:690-700.
2013
2013
Finding a new generation of spies and manuscript reviewers
.
Laboratory Investigation
. 93:1262-1264.
2013
2012
Prostatic Alpha-Linolenic Acid (ALA) Is Positively Associated with Aggressive Prostate Cancer: A Relationship Which May Depend on Genetic Variation in ALA Metabolism
.
PLoS ONE
. 7.
2012
2012
Injury-induced insulin resistance in adipose tissue
.
Biochemical and Biophysical Research Communications
. 421:442-448.
2012
2011
Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate
.
Carcinogenesis
. 32:1251-1258.
2011
2010
Performance evaluation of the new ADVIA Centaur system cyclosporine assay (single-step extraction).
.
Clinica Chimica Acta
. 411:806-811.
2010
2010
What editors want in an abstract
.
Laboratory Investigation
. 90:4-5.
2010
2009
Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance
.
Diabetes
. 58:2498-2505.
2009
2009
Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4
.
Laboratory Investigation
. 89:1221-1228.
2009
2009
Stearate preferentially induces apoptosis in human breast cancer cells
2009
2009
Transgenic expression of n-3 fatty acid desaturase (fat-1) in C57/BL6 mice: Effects on glucose homeostasis and body weight
.
Journal of Cellular Biochemistry
. 107:809-817.
2009
2009
Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice
.
Clinical and Experimental Metastasis
. 26:415-424.
2009
2008
Immunohistochemistry in the evaluation of neovascularization in tumor xenografts
2008
2007
Breast cancer metastasis to bone: Evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice
.
Clinical and Experimental Metastasis
. 24:389-401.
2007
2007
Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins
.
American Journal of Clinical Pathology
. 128:293-299.
2007
2007
Evaluation of the LIAISON chemiluminescence immunoassay for diagnosis of syphilis
2007
2006
The metabolic syndrome: A high-risk state for cancer?
.
American Journal of Pathology
. 169:1505-1522.
2006
2004
Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes
.
Biochemical Journal
. 381:463-469.
2004
2004
Overestimation of HDL-Cholesterol Using a Homogeneous "Direct" Assay
.
Journal of Clinical Laboratory Analysis
. 18:42-44.
2004
2004
C-Reactive Protein and Glycemic Control in Adults with Diabetes: Response to King et al. [23] (multiple letters)
.
Diabetes Care
. 27:637-638.
2004
2004
Pathologic quiz case: repeated positive ethylene glycol levels by gas chromatography. Central venous line contamination of blood samples by propylene glycol from intravenous lorazepam injections.
.
Archives of Pathology and Laboratory Medicine
. 128.
2004
2003
Utilization, reliability, and clinical impact of point-of-care testing during critical care transport: Six years of experience
2003
2003
Polydrug fatality involving metaxalone
.
Journal of Forensic Sciences
. 48:432-434.
2003
2002
Energy restriction reduces long-chain saturated fatty acids associated with plasma lipids in aging male rats
2002
2002
Comparison of non-diglyceride- and diglyceride-based assays for pancreatic lipase activity
.
Journal of Clinical Laboratory Analysis
. 16:52-55.
2002
2002
Detection of ketosis in vitreous at autopsy after embalming
.
Journal of Forensic Sciences
. 47:221-223.
2002
2000
New automated chemiluminescent assay for erythropoietin
.
Journal of Clinical Laboratory Analysis
. 14:271-273.
2000
2000
Phosphatase activity in rat adipocytes: Effects of insulin and insulin resistance
.
Journal of Cellular Biochemistry
. 77:445-454.
2000
2000
Phosphatase activity in rat adipocytes: effects of insulin and insulin resistance.
.
Journal of Cellular Biochemistry
. 77:445-454.
2000
2000
Automated chemiluminescent assay for C-peptide
.
Journal of Clinical Laboratory Analysis
. 14:17-19.
2000
2000
An unusual multiple drug intoxication case involving citalopram
.
Journal of Analytical Toxicology
. 24:648-650.
2000
2000
Automated chemiluminescent assay for C-peptide.
.
Journal of Clinical Laboratory Analysis
. 14:17-19.
2000
2000
Evaluation of a homogeneous direct LDL-cholesterol assay in diabetic patients: Effect of glycemic control
2000
2000
Evaluation of the Beckman Coulter LX20 clinical chemistry analyzer
.
Laboratory Medicine
. 31:387-393.
2000
1999
Evaluation of a fully automated high-performance liquid chromatography assay for hemoglobin A(1c)
.
Archives of Pathology and Laboratory Medicine
. 123:763-767.
1999
1999
False-positive cardiac troponin I results: Two case reports
.
Laboratory Medicine
. 30:610-612.
1999
1998
She phosphorylation and movement from the plasma membrane to the cytosol is altered in fatty acid-induced insulin resistant rat adipocytes
.
The FASEB Journal
. 12.
1998
1997
A rolf. fur phospholipasl c activation in gi.ut4mediated glucose transport
.
The FASEB Journal
. 11.
1997
1997
Regulation of osteoclastic bone resorption by glucose
.
Biochemical and Biophysical Research Communications
. 235:646-651.
1997
1997
A role for phospholipase C activity in GLUT4-mediated glucose transport
.
Endocrinology
. 138:5170-5175.
1997
1997
Fatty acid-induced insulin resistance in adipocytes
.
Endocrinology
. 138:4338-4345.
1997
1997
Fatty acids and breast cancer cell proliferation
.
Advances in Experimental Medicine and Biology
. 422:57-69.
1997
1996
Long chain saturated fatty acids inhibit glut4 activation in rat adipocytes
.
The FASEB Journal
. 10.
1996
1996
Stearate inhibition of breast cancer cell proliferation: A mechanism involving epidermal growth factor receptor and G-proteins
.
American Journal of Pathology
. 148:987-995.
1996
1996
Epidermal growth factor induces glucose storage in transgenic 3T3-L1 adipocytes overexpressing epidermal growth factor receptors
.
Diabetes
. 45:1619-1625.
1996
1995
Stearate inhibits human tumor cell invasion
1995
1995
Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes
.
Endocrinology
. 136:431-439.
1995
1994
Variability in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in women receiving adjuvant treatment for breast cancer
.
Cancer Chemotherapy and Pharmacology
. 33:472-476.
1994
1994
The interaction of calmodulin and polylysine as studied by
1
H NMR spectroscopy and sedimentation equilibrium centrifugation
.
Biochemical and Biophysical Research Communications
. 198:309-317.
1994
1994
Calmodulin concentrated at the osteoclast ruffled border modulates acid secretion
.
Journal of Cellular Physiology
. 160:17-28.
1994
1994
Saturated fatty acid-induced insulin resistance in rat adipocytes
.
Diabetes
. 43:540-545.
1994
1992
A multicenter evaluation of lipid profiling with a compact analyzer (Miles Clinistat).
1992
1992
A multicenter evaluation of lipid profiling with a compact analyzer (Miles Clinistat)
1992
1992
The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes
.
Endocrinology
. 130:3694-3702.
1992
1991
Palmitate stimulates glucose transport in rat adipocytes by a mechanism involving translocation of the insulin sensitive glucose transporter (GLUT4)
.
Biochemical and Biophysical Research Communications
. 177:343-349.
1991
1989
Expression and function of HLA‐A2.1 in transgenic mice
.
European Journal of Immunology
. 19:1575-1583.
1989
1989
Letter to the Editor: The effects of hyperlipidaemia, hyperbilirubinaemia and haemolysis on tests performed by the Olympus AU 5000 multiple analyser
.
The Journal of automatic chemistry
. 11:89-90.
1989
1989
Palmitic acid stimulates glucose incorporation in the adipocyte by a mechanism likely involving intracellular calcium
.
Journal of Lipid Research
. 30:1299-1305.
1989
1988
Disposition of cyclophosphamide on two consecutive cycles of treatment in patients with ovarian carcinoma
1988
1988
Rapid development of enhanced clearance after high-dose cyclophosphamide
.
Clinical Pharmacology and Therapeutics
. 44:622-628.
1988
1987
31
P nmr and hplc investigations of the cyclophosphamide metabolite, phosphoramme mustard
.
Analytical Letters
. 20:1303-1314.
1987
1987
Analysis of phosphor amide mustard by reversed-phase ion pair high pressure liquid chromatography
.
Therapeutic Drug Monitoring
. 9:221-226.
1987
1984
High-performance liquid chromatographic measurement of cyclophosphamide in serum
.
Therapeutic Drug Monitoring
. 6:313-318.
1984
Research
Principal Investigator On
Private Grant
awarded by
Siemens
Teaching
Teaching Activities
DENT1150 - Fundamentals I (Fall Term 2012)
DENT1150 - Fundamentals I (Fall Term 2013)
DENT1150 - Fundamentals I (Fall Term 2014)
DENT1150 - Fundamentals I (Fall Term 2015)
DENT1150 - Fundamentals I (Fall Term 2016)
DENT1150 - Fundamentals I (Fall Term 2017)
DENT1150 - Fundamentals I (Fall Term 2018)
DENT1150 - Fundamentals I (Fall Term 2019)
DENT1150R - Remediation Fundamentals I (Fall Term 2015)
DENT1150R - Remediation Fundamentals I (Spring Term 2013)
DENT1155 - Fundamentals II (Fall Term 2012)
DENT1155 - Fundamentals II (Fall Term 2013)
DENT1155 - Fundamentals II (Fall Term 2014)
DENT1155 - Fundamentals II (Fall Term 2015)
DENT1155 - Fundamentals II (Fall Term 2016)
DENT1155 - Fundamentals II (Fall Term 2017)
DENT1155 - Fundamentals II (Fall Term 2018)
DENT1155 - Fundamentals II (Fall Term 2019)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2012)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2013)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2014)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2015)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2016)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2017)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2018)
OBHS111 - Fundamentals Dent/Optometry I (Fall Term 2019)
OBHS111 - Fundamentals Dent/Optometry I (Spring Term 2015)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2012)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2013)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2014)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2015)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2016)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2017)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2018)
OBHS112 - Fundamentals Dent/Optometry II (Fall Term 2019)
OBHS112 - Fundamentals Dent/Optometry II (Spring Term 2015)
OBHS112 - Fundamentals Dent/Optometry II (Spring Term 2016)
OBHS112 - Fundamentals Dent/Optometry II (Spring Term 2017)
OBHS112 - Fundamentals Dent/Optometry II (Spring Term 2020)
Background
Education And Training
Doctor of Philosophy in Biochemistry,
University of Toronto
1988
Contact
Full Name
Robert
Hardy