Robert Hardy Ph.D.

Robert Hardy Ph.D.
Professor

Associate Scientist (C), Integrative Center for Aging Research , School of Medicine 1997 -
Assistant Professor (S), Nutrition Sciences - Phys & Metabolism (Retired Org) , Nutrition Sciences 1998 -
Assistant Professor (S), Clin Lab Sci Division (Retired Org) , School of Health Professions 2000 -
Associate Scientist (C), Clin Nutrition Res (Retired Org) , Nutrition Sciences - Phys & Metabolism (Retired Org) 2000 -
Professor (P), Laboratory Medicine , Clinical Pathology 2005 -
Senior Scientist (C), Nutrition Obesity Res Center (NORC) , Nutrition Sciences Research 2008 -
Scientist (C), Comprehensive Diabetes Center , School of Medicine 2011 -
Professor (S), Cell, Developmental and Integrative Biology (CDIB) , Academic Joint Departments 2012 -
Professor (S), Restorative Sciences , School of Dentistry 2013 -
Senior Scientist (C), Comprehensive Arthritis, Musculoskeletal, Bone and Autoimmunity Center (CAMBAC) , School of Medicine 2016 -
Senior Scientist (C), O'Neal Comprehensive Cancer Center , School of Medicine 2019 -

Selected Publications

Academic Article

Year	Title	Altmetric
2014	Dietary stearic acid leads to a reduction of visceral adipose tissue in athymic nude mice. PLoS ONE. 9. 2014
2014	Diet modulation is an effective complementary agent in preventing and treating breast cancer lung metastasis. Clinical and Experimental Metastasis. 31:625-638. 2014
2014	The Bioenergetic Health Index: a new concept in mitochondrial translational research.. Clinical Science. 127:367-373. 2014
2013	Methods for defining distinct bioenergetic profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Laboratory Investigation. 93:690-700. 2013
2013	Finding a new generation of spies and manuscript reviewers. Laboratory Investigation. 93:1262-1264. 2013
2012	Prostatic Alpha-Linolenic Acid (ALA) Is Positively Associated with Aggressive Prostate Cancer: A Relationship Which May Depend on Genetic Variation in ALA Metabolism. PLoS ONE. 7. 2012
2012	Injury-induced insulin resistance in adipose tissue. Biochemical and Biophysical Research Communications. 421:442-448. 2012
2011	Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. Carcinogenesis. 32:1251-1258. 2011
2010	Performance evaluation of the new ADVIA Centaur system cyclosporine assay (single-step extraction).. Clinica Chimica Acta. 411:806-811. 2010
2010	What editors want in an abstract. Laboratory Investigation. 90:4-5. 2010
2009	Adipose tissue exosome-like vesicles mediate activation of macrophage-induced insulin resistance. Diabetes. 58:2498-2505. 2009
2009	Free fatty acids enhance breast cancer cell migration through plasminogen activator inhibitor-1 and SMAD4. Laboratory Investigation. 89:1221-1228. 2009
2009	Stearate preferentially induces apoptosis in human breast cancer cells 2009
2009	Transgenic expression of n-3 fatty acid desaturase (fat-1) in C57/BL6 mice: Effects on glucose homeostasis and body weight. Journal of Cellular Biochemistry. 107:809-817. 2009
2009	Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice. Clinical and Experimental Metastasis. 26:415-424. 2009
2008	Immunohistochemistry in the evaluation of neovascularization in tumor xenografts 2008
2007	Breast cancer metastasis to bone: Evaluation of bioluminescent imaging and microSPECT/CT for detecting bone metastasis in immunodeficient mice. Clinical and Experimental Metastasis. 24:389-401. 2007
2007	Performance of the Sebia CAPILLARYS 2 for detection and immunotyping of serum monoclonal paraproteins. American Journal of Clinical Pathology. 128:293-299. 2007
2007	Evaluation of the LIAISON chemiluminescence immunoassay for diagnosis of syphilis 2007
2006	The metabolic syndrome: A high-risk state for cancer?. American Journal of Pathology. 169:1505-1522. 2006
2004	Long-chain saturated fatty acids induce annexin II translocation to detergent-resistant membranes. Biochemical Journal. 381:463-469. 2004
2004	Overestimation of HDL-Cholesterol Using a Homogeneous "Direct" Assay. Journal of Clinical Laboratory Analysis. 18:42-44. 2004
2004	C-Reactive Protein and Glycemic Control in Adults with Diabetes: Response to King et al. [23] (multiple letters). Diabetes Care. 27:637-638. 2004
2004	Pathologic quiz case: repeated positive ethylene glycol levels by gas chromatography. Central venous line contamination of blood samples by propylene glycol from intravenous lorazepam injections.. Archives of Pathology and Laboratory Medicine. 128. 2004
2003	Utilization, reliability, and clinical impact of point-of-care testing during critical care transport: Six years of experience 2003
2003	Polydrug fatality involving metaxalone. Journal of Forensic Sciences. 48:432-434. 2003
2002	Energy restriction reduces long-chain saturated fatty acids associated with plasma lipids in aging male rats 2002
2002	Comparison of non-diglyceride- and diglyceride-based assays for pancreatic lipase activity. Journal of Clinical Laboratory Analysis. 16:52-55. 2002
2002	Detection of ketosis in vitreous at autopsy after embalming. Journal of Forensic Sciences. 47:221-223. 2002
2000	New automated chemiluminescent assay for erythropoietin. Journal of Clinical Laboratory Analysis. 14:271-273. 2000
2000	Phosphatase activity in rat adipocytes: Effects of insulin and insulin resistance. Journal of Cellular Biochemistry. 77:445-454. 2000
2000	Phosphatase activity in rat adipocytes: effects of insulin and insulin resistance.. Journal of Cellular Biochemistry. 77:445-454. 2000
2000	Automated chemiluminescent assay for C-peptide. Journal of Clinical Laboratory Analysis. 14:17-19. 2000
2000	An unusual multiple drug intoxication case involving citalopram. Journal of Analytical Toxicology. 24:648-650. 2000
2000	Automated chemiluminescent assay for C-peptide.. Journal of Clinical Laboratory Analysis. 14:17-19. 2000
2000	Evaluation of a homogeneous direct LDL-cholesterol assay in diabetic patients: Effect of glycemic control 2000
2000	Evaluation of the Beckman Coulter LX20 clinical chemistry analyzer. Laboratory Medicine. 31:387-393. 2000
1999	Evaluation of a fully automated high-performance liquid chromatography assay for hemoglobin A(1c). Archives of Pathology and Laboratory Medicine. 123:763-767. 1999
1999	False-positive cardiac troponin I results: Two case reports. Laboratory Medicine. 30:610-612. 1999
1998	She phosphorylation and movement from the plasma membrane to the cytosol is altered in fatty acid-induced insulin resistant rat adipocytes. The FASEB Journal. 12. 1998
1997	A rolf. fur phospholipasl c activation in gi.ut4mediated glucose transport. The FASEB Journal. 11. 1997
1997	Regulation of osteoclastic bone resorption by glucose. Biochemical and Biophysical Research Communications. 235:646-651. 1997
1997	A role for phospholipase C activity in GLUT4-mediated glucose transport. Endocrinology. 138:5170-5175. 1997
1997	Fatty acid-induced insulin resistance in adipocytes. Endocrinology. 138:4338-4345. 1997
1997	Fatty acids and breast cancer cell proliferation. Advances in Experimental Medicine and Biology. 422:57-69. 1997
1996	Long chain saturated fatty acids inhibit glut4 activation in rat adipocytes. The FASEB Journal. 10. 1996
1996	Stearate inhibition of breast cancer cell proliferation: A mechanism involving epidermal growth factor receptor and G-proteins. American Journal of Pathology. 148:987-995. 1996
1996	Epidermal growth factor induces glucose storage in transgenic 3T3-L1 adipocytes overexpressing epidermal growth factor receptors. Diabetes. 45:1619-1625. 1996
1995	Stearate inhibits human tumor cell invasion 1995
1995	Epidermal growth factor (EGF) receptor carboxy-terminal domains are required for EGF-induced glucose transport in transgenic 3T3-L1 adipocytes. Endocrinology. 136:431-439. 1995
1994	Variability in the pharmacokinetics of cyclophosphamide, methotrexate and 5-fluorouracil in women receiving adjuvant treatment for breast cancer. Cancer Chemotherapy and Pharmacology. 33:472-476. 1994
1994	The interaction of calmodulin and polylysine as studied by ¹H NMR spectroscopy and sedimentation equilibrium centrifugation. Biochemical and Biophysical Research Communications. 198:309-317. 1994
1994	Calmodulin concentrated at the osteoclast ruffled border modulates acid secretion. Journal of Cellular Physiology. 160:17-28. 1994
1994	Saturated fatty acid-induced insulin resistance in rat adipocytes. Diabetes. 43:540-545. 1994
1992	A multicenter evaluation of lipid profiling with a compact analyzer (Miles Clinistat). 1992
1992	A multicenter evaluation of lipid profiling with a compact analyzer (Miles Clinistat) 1992
1992	The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes. Endocrinology. 130:3694-3702. 1992
1991	Palmitate stimulates glucose transport in rat adipocytes by a mechanism involving translocation of the insulin sensitive glucose transporter (GLUT4). Biochemical and Biophysical Research Communications. 177:343-349. 1991
1989	Expression and function of HLA‐A2.1 in transgenic mice. European Journal of Immunology. 19:1575-1583. 1989
1989	Letter to the Editor: The effects of hyperlipidaemia, hyperbilirubinaemia and haemolysis on tests performed by the Olympus AU 5000 multiple analyser. The Journal of automatic chemistry. 11:89-90. 1989
1989	Palmitic acid stimulates glucose incorporation in the adipocyte by a mechanism likely involving intracellular calcium. Journal of Lipid Research. 30:1299-1305. 1989
1988	Disposition of cyclophosphamide on two consecutive cycles of treatment in patients with ovarian carcinoma 1988
1988	Rapid development of enhanced clearance after high-dose cyclophosphamide. Clinical Pharmacology and Therapeutics. 44:622-628. 1988
1987	³¹P nmr and hplc investigations of the cyclophosphamide metabolite, phosphoramme mustard. Analytical Letters. 20:1303-1314. 1987
1987	Analysis of phosphor amide mustard by reversed-phase ion pair high pressure liquid chromatography. Therapeutic Drug Monitoring. 9:221-226. 1987
1984	High-performance liquid chromatographic measurement of cyclophosphamide in serum. Therapeutic Drug Monitoring. 6:313-318. 1984