• Dr. Russell received his initial medical training (MD) at the University of Texas Medical Branch with his internal medicine internship and residency completed at Vanderbilt University. Dr. Russell began a clinical and research fellowship in pulmonary and critical care medicine at UAB in 2014. Following his fellowship, he joined the UAB faculty in July 2017. His research and clinical interests relate to the role of neutrophils and extracellular vesicles in pulmonary diseases characterized by neutrophilic inflammation and parenchymal damage such as COPD and ARDS, as well as pragmatic clinical trials on the management of critically ill patients. Dr. Russell has published and presented work on endotracheal intubation, management of respiratory failure, pragmatic clinical trials in the MICU, neutrophils in COPD, matrikines in COPD, exhaled breath biomarkers in ARDS and extracellular vesicles in neutrophilic inflammation. His ongoing work explores the role of neutrophil-derived exosomes in matrix destruction and lung disease.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2019 Benzyloxycarbonyl-proline-prolinal (ZPP): Dual complementary roles for neutrophil inhibition 2019
    2019 Emulating a Novel Clinical Trial Using Existing Observational Data. Predicting Results of the PreVent Study 2019
    2019 Bag-mask ventilation during tracheal intubation of critically ill adults 2019
    2019 Activated PMN Exosomes: Pathogenic Entities Causing Matrix Destruction and Disease in the Lung 2019
    2018 ADAM9: A damaging player in chronic obstructive pulmonary disease 2018
    2018 Letter by Russell and Janz Regarding Article, "Association Between Early Hyperoxia Exposure After Resuscitation From Cardiac Arrest and Neurological Disability: A Prospective Multicenter Protocol-Directed Cohort Study" 2018
    2018 Risk factors for and prediction of hypoxemia during tracheal intubation of Critically Ill Adults 2018
    2018 Searching for the source of the leak: PIE and the macklin effect 2018
    2018 COPD ground zero: small airways rather than alveoli as the initial site of injury 2018
    2018 Manual ventilation to prevent hypoxaemia during endotracheal intubation of critically ill adults: Protocol and statistical analysis plan for a multicentre randomised trial 2018
    2018 Fibroblast growth factor 23 and Klotho contribute to airway inflammation 2018
    2018 Novel method for noninvasive sampling of the distal airspace in acute respiratory distress syndrome 2018
    2018 Exosomal microRNA predicts and protects against severe bronchopulmonary dysplasia in extremely premature infants 2018
    2018 Response 2018
    2017 Response 2017
    2017 Response 2017
    2017 A Multicenter, Randomized Trial of Ramped Position vs Sniffing Position During Endotracheal Intubation of Critically Ill Adults 2017
    2017 Early exposure to hyperoxia and mortality in critically ill patients with severe traumatic injuries 2017
    2016 Neutrophil fates in bronchiectasis and alpha-1 antitrypsin deficiency 2016
    2016 Disease phenotyping in chronic obstructive pulmonary disease: The neutrophilic endotype 2016
    2015 The soot of all evil 2015

    Research Overview

  • Dr. Russell's research interests include Biomarkers in inflammatory lung diseases such as COPD and ARDS, Extracellular vesicles, Exosomes, Innate immune cells such as neutrophils and their interaction with extracellular matrix, Pragmatic Clinical Trials in the critically ill, Translational Medicine, and Respiratory Failure
  • Investigator On

  • Private Grant  awarded by Ferring Pharmaceuticals 2016 - 2018
  • Private Grant  awarded by LA JOLLA PHARMACEUTICAL COMPANY 2015 - 2018
  • Education And Training

  • University of Alabama at Birmingham Division of Pulmonary, Allergy, and Critical Care Medicine; Department of Medicine, Postdoctoral Fellowship
  • Vanderbilt University, Residency 2014
  • Vanderbilt University Medical Center Department of Medicine, Residency 2014
  • University of Alabama at Birmingham, Postdoctoral Fellowship 2017
  • University of Alabama at Birmingham Division of Pulmonary, Allergy, and Critical Care Medicine; Department of Medicine, Postdoctoral Fellowship 2017
  • Full Name

  • Derek Russell