• Richard Myers, Ph.D., received his B.S. in biochemistry from the University of Alabama in 1977, his Ph.D. in biochemistry from the University of California at Berkeley and performed post-doctoral work at Harvard University. He began his first faculty position at the University of California at San Francisco in 1986 and moved his laboratory to Stanford University’s Department of Genetics in 1993. At Stanford, he was chair of the Department of Genetics and director of the Stanford Human Genome Center, which contributed more than 10 percent of the data in the public Human Genome Project’s efforts to sequence the human genome. Dr. Myers moved to HudsonAlpha in July 2008.

    Myers’s research program is focused on human genetics and genomics. Work in his laboratory has led to the identification of genes involved in several inherited diseases, and his genome center contributed more than 10 percent of the data in the public Human Genome Project’s efforts to sequence the human genome. His lab continues to use genomics tools and genetics to understand how genes interacting with the environment contribute to human diseases and other traits.

    Myers has won several awards, including the Pritzker Award and an honorary doctorate of human letters from the University of Alabama. He is an editor of Genome Research and reviews manuscripts for a variety of other journals.
  • Selected Publications

    Academic Article

    Year Title Altmetric
    2021 The Multi-Partner Consortium to Expand Dementia Research in Latin America (ReDLat): Driving Multicentric Research and Implementation ScienceFrontiers in Neurology.  12. 2021
    2020 Corrigendum: Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 Patients(Front. Immunol., (2020), 11, (582010), 10.3389/fimmu.2020.582010)Frontiers in Immunology.  11. 2020
    2020 Longitudinal Analysis of T and B Cell Receptor Repertoire Transcripts Reveal Dynamic Immune Response in COVID-19 PatientsFrontiers in Immunology.  11. 2020
    2020 Response to Holstege et al.American Journal of Human Genetics.  107:577-578. 2020
    2020 Assembly of the threespine stickleback y chromosome reveals convergent signatures of sex chromosome evolutionGenome Biology.  21. 2020
    2020 The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 ControlsBiological Psychiatry.  88:169-184. 2020
    2020 Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations 2020
    2020 Non-coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative DiseasesAmerican Journal of Human Genetics.  106:632-645. 2020
    2020 TBCRC 002: A phase II, randomized, open-label trial of preoperative letrozole with or without bevacizumab in postmenopausal women with newly diagnosed stage 2/3 hormone receptor-positive and HER2-negative breast cancerBreast Cancer Research.  22. 2020
    2019 Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric DisordersCell.  179:1469-1482.e11. 2019
    2019 Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of CtcfCell Reports.  29:1203-1220.e7. 2019
    2019 Determining the Origins of Human Immunodeficiency Virus Type 1 Drug-resistant Minority Variants in People Who Are Recently Infected Using Phylogenetic ReconstructionClinical Infectious Diseases.  69:1136-1143. 2019
    2019 Transmembrane Protein Aptamer Induces Cooperative Signaling by the EPO Receptor and the Cytokine Receptor β-Common SubunitiScience.  17:167-181. 2019
    2019 Tumour-specific amplitude-modulated radiofrequency electromagnetic fields induce differentiation of hepatocellular carcinoma via targeting Cav3.2 T-type voltage-gated calcium channels and Ca2+ influxEBioMedicine.  44:209-224. 2019
    2019 A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS 2019
    2019 Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr)Alzheimer's and Dementia.  15:709-719. 2019
    2019 HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor SuppressioniScience.  13:43-54. 2019
    2019 Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasisAnnals of the Rheumatic Diseases.  78:355-364. 2019
    2019 Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasisAnnals of the Rheumatic Diseases.  78:355-364. 2019
    2019 Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementiaActa Neuropathologica.  137:71-88. 2019
    2019 Dynamics of microRNA expression during mouse prenatal development 2019
    2019 Genome sequencing for early-onset or atypical dementia: High diagnostic yield and frequent observation of multiple contributory allelesCold Spring Harbor molecular case studies.  5. 2019
    2018 Aberrant Inclusion of a Poison Exon Causes Dravet Syndrome and Related SCN1A-Associated Genetic EpilepsiesAmerican Journal of Human Genetics.  103:1022-1029. 2018
    2018 Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorderCommunications Biology.  1. 2018
    2018 Genomic sequencing identifies secondary findings in a cohort of parent study participantsGenetics in Medicine.  20:1635-1643. 2018
    2018 Connective Tissue Growth Factor Is a Novel ProdepressantBiological Psychiatry.  84:555-562. 2018
    2018 SnapperDB: a database solution for routine sequencing analysis of bacterial isolatesBioinformatics.  34:3028-3029. 2018
    2018 Control of artifactual variation in reported intersample relatedness during clinical use of a mycobacterium tuberculosis sequencing pipelineJournal of Clinical Microbiology.  56. 2018
    2018 Systematic reanalysis of genomic data improves quality of variant interpretation 2018
    2018 A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed frameworkBMC Genomics.  19. 2018
    2018 Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 SubphenotypesCell.  173:1705-1715.e16. 2018
    2018 Discovery and validation of circulating biomarkers of colorectal adenoma by high-depth small RNA sequencingClinical Cancer Research.  24:2092-2099. 2018
    2018 Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations 2018
    2018 Evidence for a pan-neurodegenerative disease response in Huntington’s and Parkinson’s disease expression profilesFrontiers in Molecular Neuroscience.  10. 2018
    2017 Stress amplifies sex differences in primate prefrontal profiles of gene expressionBiology of Sex Differences.  8. 2017
    2017 A genome-wide interactome of DNA-associated proteins in the human liver 2017
    2017 Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysisBiological Psychiatry.  82:634-641. 2017
    2017 Haplotype-based stratification of Huntington's diseaseEuropean Journal of Human Genetics.  25:1202-1209. 2017
    2017 A modifier of Huntington's disease onset at the MLH1 locusHuman Molecular Genetics.  26:3859-3867. 2017
    2017 CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene ProgramsImmunity.  47:251-267.e7. 2017
    2017 Molecular surveillance of measles and rubella in the WHO European Region: new challenges in the elimination phaseClinical Microbiology and Infection.  23:516-523. 2017
    2017 Post-mortem molecular profiling of three psychiatric disorders 2017
    2017 Epigenome-wide association study of rheumatoid arthritis identifies differentially methylated loci in B cellsHuman Molecular Genetics.  26:2803-2811. 2017
    2017 Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus 2017
    2017 ARNApipe: A balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environmentsBioinformatics.  33:1727-1729. 2017
    2017 Genomic diagnosis for children with intellectual disability and/or developmental delay 2017
    2017 Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patternsBMC Cancer.  17. 2017
    2017 Eliciting preferences on secondary findings: The Preferences Instrument for Genomic Secondary ResultsGenetics in Medicine.  19:337-344. 2017
    2017 Evaluation of logistic regression models and effect of covariates for case-control study in RNA-Seq analysisBMC Bioinformatics.  18. 2017
    2017 Mutations in EBF3 Disturb Transcriptional Profiles and Cause Intellectual Disability, Ataxia, and Facial DysmorphismAmerican Journal of Human Genetics.  100:117-127. 2017
    2017 Enhanced surveillance of HIV-1 drug resistance in recently infected MSM in the UKJournal of Antimicrobial Chemotherapy.  72:227-234. 2017
    2016 Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2Journal of Bone and Mineral Research.  31:2085-2097. 2016
    2016 Novel microRNA discovery using small RNA sequencing in post-mortem human brainBMC Genomics.  17. 2016
    2016 Comparison of next-generation sequencing technologies for comprehensive assessment of full-length hepatitis C viral genomesJournal of Clinical Microbiology.  54:2470-2484. 2016
    2016 De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability SyndromeAmerican Journal of Human Genetics.  99:711-719. 2016
    2016 Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation 2016
    2016 Erratum: Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine (American Journal of Human Genetics (2016) 98(6) (1067–1076) (S0002929716301069) (10.1016/j.ajhg.2016.04.011))American Journal of Human Genetics.  99:246. 2016
    2016 Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic MedicineAmerican Journal of Human Genetics.  98:1051-1066. 2016
    2016 Identification of IRX1 as a Risk Locus for Rheumatoid Factor Positivity in Rheumatoid Arthritis in a Genome-Wide Association StudyArthritis and Rheumatology.  68:1384-1391. 2016
    2016 microRNA profiles in Parkinson's disease prefrontal cortexFrontiers in Aging Neuroscience.  8. 2016
    2016 Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson diseaseBMC Medical Genomics.  9. 2016
    2016 Evolving New Skeletal Traits by cis-Regulatory Changes in Bone Morphogenetic ProteinsCell.  164:45-56. 2016
    2016 Clinical-genetic associations in the Prospective Huntington at Risk Observational Study (PHAROS) implications for clinical trialsJAMA Neurology.  73:102-110. 2016
    2016 Whole-exome sequencing in familial Parkinson diseaseJAMA Neurology.  73:68-75. 2016
    2015 Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites 2015
    2015 A deletion at adamts9-magi1 locus is associated with psoriatic arthritis riskAnnals of the Rheumatic Diseases.  74:1875-1881. 2015
    2015 CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins 2015
    2015 The Genetic Modifiers of Motor OnsetAge (GeM MOA) Website: Genome-wide Association Analysis for Genetic Modifiers of Huntington's DiseaseJournal of Huntington's Disease.  4:279-284. 2015
    2015 Sequence-Level Analysis of the Major European Huntington Disease HaplotypeAmerican Journal of Human Genetics.  97:435-444. 2015
    2015 Identification of Genetic Factors that Modify Clinical Onset of Huntington's DiseaseCell.  162:516-526. 2015
    2015 TBCRC 019: A phase II trial of nanoparticle albumin-bound paclitaxel with or without the anti-death receptor 5 monoclonal antibody tigatuzumab in patients with triple-negative breast cancerClinical Cancer Research.  21:2722-2729. 2015
    2015 Genome sequence analysis of Ebola virus in clinical samples from three British healthcare workers, august 2014 to march 2015Eurosurveillance.  20. 2015
    2015 Identification of risk loci for crohn's disease phenotypes using a genome-wide association studyGastroenterology.  148:794-805. 2015
    2015 MiR-10b-5p expression in Huntington's disease brain relates to age of onset and the extent of striatal involvementBMC Medical Genomics.  8. 2015
    2015 Joint analysis of psychiatric disorders increases accuracy of risk prediction for schizophrenia, bipolar disorder, and major depressive disorderAmerican Journal of Human Genetics.  96:283-294. 2015
    2015 Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brainsHuman Molecular Genetics.  24:1441-1456. 2015
    2014 A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitisHuman Molecular Genetics.  23:6927-6934. 2014
    2014 DNA methylation profiling reveals novel diagnostic biomarkers in renal cell carcinomaBMC Medicine.  12. 2014
    2014 Identification of pathways for bipolar disorder: A meta-analysisJAMA Psychiatry.  71:657-664. 2014
    2014 Altered choroid plexus gene expression in major depressive disorderFrontiers in Human Neuroscience.  8. 2014
    2014 Correction for multiple testing in a gene regionEuropean Journal of Human Genetics.  22:414-418. 2014
    2014 Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysisHuman Brain Mapping.  35:792-809. 2014
    2014 From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing 2014
    2014 Recurrent read-through fusion transcripts in breast cancerBreast Cancer Research and Treatment.  146:287-297. 2014
    2013 G protein-linked signaling pathways in bipolar and major depressive disordersFrontiers in Genetics.  4. 2013
    2013 Integrating and mining the chromatin landscape of cell-type specificity using self-organizing maps 2013
    2013 Mapping genome-wide transcription factor binding sites in frozen tissues 2013
    2013 Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscapeGenome Biology.  14. 2013
    2013 A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse modelCell Reports.  4:385-401. 2013
    2013 The 'Red Queen' dilemma - Running to stay in the same place: Reflections on the evolutionary vector of HBV in humansAntiviral Therapy.  18:489-496. 2013
    2013 Dynamic DNA methylation across diverse human cell lines and tissues 2013
    2013 Early de novo DNA methylation and prolonged demethylation in the muscle lineageEpigenetics.  8:317-332. 2013
    2012 Evidence for transcriptional factor dysregulation in the dorsal raphe nucleus of patients with major depressive disorderFrontiers in Neuroscience2012
    2012 Population stratiWcation may bias analysis of PGC-1α as a modiWer of age at Huntington disease motor onsetHuman Genetics.  131:1833-1840. 2012
    2012 Theria-Specific Homeodomain and cis-Regulatory Element Evolution of the Dlx3-4 Bigene Cluster in 12 Different Mammalian SpeciesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution.  318:639-650. 2012
    2012 Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner 2012
    2012 A validated regulatory network for Th17 cell specificationCell.  151:289-303. 2012
    2012 Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012Eurosurveillance.  17. 2012
    2012 Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstructionAmerican Journal of Respiratory and Critical Care Medicine.  186:622-632. 2012
    2012 Functional analysis of transcription factor binding sites in human promotersGenome Biology.  13. 2012
    2012 ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia 2012
    2012 Genetic architecture of variation in the lateral line sensory system of threespine sticklebacks 2012
    2012 Phylodynamic and phylogeographic patterns of the HIV type 1 subtype F1 parenteral epidemic in RomaniaAIDS Research and Human Retroviruses.  28:961-966. 2012
    2012 Sequence features and chromatin structure around the genomic regions bound by 119 human transcription factors 2012
    2012 Widespread plasticity in CTCF occupancy linked to DNA methylation 2012
    2012 Genomic patterns of homozygosity in worldwide human populationsAmerican Journal of Human Genetics.  91:275-292. 2012
    2012 TAA repeat variation in the GRIK2 gene does not influence age at onset in Huntington's diseaseBiochemical and Biophysical Research Communications.  424:404-408. 2012
    2012 Effects of sequence variation on differential allelic transcription factor occupancy and gene expression 2012
    2012 Dynamic microRNA gene transcription and processing during T cell developmentJournal of Immunology.  188:3257-3267. 2012
    2012 Common SNP-based haplotype analysis of the 4p16.3 Huntington disease gene regionAmerican Journal of Human Genetics.  90:434-444. 2012
    2012 Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2Annals of Neurology.  71:370-384. 2012
    2012 Transposase mediated construction of RNA-seq libraries (Genome Research (2012) 22, (134-141)) 2012
    2012 Identification of a Functional In Vivo p53 Response Element in the Coding Sequence of the Xeroderma Pigmentosum Group C GeneGenes and Cancer.  3:131-140. 2012
    2012 Molecular epidemiology of a large community-based outbreak of hepatitis B in Bristol, UKJournal of Clinical Virology.  53:125-129. 2012
    2012 Cancer cell proliferation is inhibited by specific modulation frequenciesBritish Journal of Cancer.  106:307-313. 2012
    2012 A genome-wide SNP genotyping array reveals patterns of global and repeated species-pair divergence in sticklebacksCurrent Biology.  22:83-90. 2012
    2012 Transposase mediated construction of RNA-seq libraries 2012
    2011 Allele-specific distribution of RNA polymerase II On female X chromosomesHuman Molecular Genetics.  20:3964-3973. 2011
    2011 Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetesDiabetes.  60:2624-2634. 2011
    2011 Erratum: Generation of isogenic pluripotent stem cells differing exclusively at two early onset parkinson point mutations (Cell (2011) 146 (318-331))Cell.  146:659. 2011
    2011 The genetic basis of divergent pigment patterns in juvenile threespine sticklebacksHeredity.  107:155-166. 2011
    2011 Generation of isogenic pluripotent stem cells differing exclusively at two early onset parkinson point mutationsCell.  146:318-331. 2011
    2011 DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer 2011
    2011 Erratum: Mitochondrial involvement in psychiatric disorders (Annals of Medicine (2008) 40 (281-295))Annals of Medicine.  43:329. 2011
    2011 Coffee, ADORA2A, and CYP1A2: The caffeine connection in Parkinson's diseaseEuropean Journal of Neurology.  18:756-765. 2011
    2011 Investigating transmission of Mycobacterium bovis in the United Kingdom in 2005 to 2008Journal of Clinical Microbiology.  49:1943-1950. 2011
    2011 Appearance of a novel measles G3 strain in multiple European countries within a two month period, 2010Eurosurveillance.  16. 2011
    2011 Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: Results from the GenePD StudyHuman Molecular Genetics.  20:1478-1487. 2011
    2011 Three residues in HIV-1 matrix contribute to protease inhibitor susceptibility and replication capacityAntimicrobial Agents and Chemotherapy.  55:1106-1113. 2011
    2010 Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's diseaseExperimental Neurology.  226:207-217. 2010
    2010 Expression patterns of corticotropin-releasing factor, arginine vasopressin, histidine decarboxylase, melanin-concentrating hormone, and orexin genes in the human hypothalamusJournal of Comparative Neurology.  518:4591-4611. 2010
    2010 Pandemic (H1N1) 2009 influenza in the UK: Clinical and epidemiological findings from the first few hundred (FF100) casesEpidemiology and Infection.  138:1531-1541. 2010
    2010 Sequence features that drive human promoter function and tissue specificity 2010
    2010 Risk of Parkinson's disease after tamoxifen treatmentBMC Neurology.  10. 2010
    2010 Evolutionary constraint facilitates interpretation of genetic variation in resequenced human genomes 2010
    2010 Characterization of X-Linked SNP genotypic variation in globally-distributed human populationsGenome Biology.  11. 2010
    2010 Estrogen-related and other disease diagnoses preceding Parkinson's diseaseClinical Epidemiology.  2:153-170. 2010
    2009 Characterizing the admixed African ancestry of African AmericansGenome Biology.  10. 2009
    2009 Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation 2009
    2009 The completion of the Mammalian Gene Collection 2009
    2009 Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivationBMC Medical Genomics.  2. 2009
    2009 Genomewide association study for onset age in Parkinson diseaseBMC Medical Genetics.  10:98. 2009
    2009 Somatic expansion of the Huntington's disease CAG repeat in the brain is associated with an earlier age of disease onsetHuman Molecular Genetics.  18:3039-3047. 2009
    2009 One step forward toward identification of the genetic signature of glioblastomas 2009
    2009 Estimating the probability of de novo HD cases from transmissions of expanded penetrant CAG alleles in the Huntington disease gene from male carriers of high normal alleles (27-35 CAG) 2009
    2009 Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver 2009
    2009 LIPC variants in the promoter and intron 1 modify HDL-C levels in a sex-specific fashionAtherosclerosis.  204:171-177. 2009
    2009 Signals of recent positive selection in a worldwide sample of human populations 2009
    2009 The association of cell cycle checkpoint 2 variants and kidney function: Findings of the family blood pressure program and the atherosclerosis risk in communities studyAmerican Journal of Hypertension.  22:552-558. 2009
    2009 Leptin is associated with blood pressure and hypertension in women from the National Heart, Lung, and Blood Institute family heart studyHypertension.  53:473-479. 2009
    2009 Genomewide association study for susceptibility genes contributing to familial Parkinson diseaseHuman Genetics.  124:593-605. 2009
    2009 Analysis of the genetic variability of the mumps SH gene in viruses circulating in the UK between 1996 and 2005Infection, Genetics and Evolution.  9:71-80. 2009
    2009 Genetic effect on blood pressure is modulated by age the hypertension genetic epidemiology network studyHypertension.  53:35-41. 2009
    2008 Development and optimization of an internally controlled dried blood spot assay for surveillance of human immunodeficiency virus type-1 drug resistanceJournal of Antimicrobial Chemotherapy.  62:1191-1198. 2008
    2008 The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: The GenePD studyBMC Medicine.  6. 2008
    2008 Model-based analysis of ChIP-Seq (MACS)Genome Biology.  9. 2008
    2008 Population analysis of large copy number variants and hotspots of human genetic diseaseAmerican Journal of Human Genetics.  84:148-161. 2008
    2008 Replication of association between ELAVL4 and Parkinson disease: The Gene PD studyHuman Genetics.  124:95-99. 2008
    2008 Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE studyHuman Molecular Genetics.  17:2320-2328. 2008
    2008 Circulating soluble ICAM-1 levels shows linkage to ICAM gene cluster region on chromosome 19: The NHLBI Family Heart Study follow-up examinationAtherosclerosis.  199:172-178. 2008
    2008 NYD-SP18 is associated with obesity in the NHLBI Family Heart StudyInternational Journal of Obesity.  32:930-935. 2008
    2008 Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart StudyBMC Medical Genetics.  9. 2008
    2008 A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery diseaseAtherosclerosis.  198:136-144. 2008
    2008 Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery diseaseHuman Genetics.  123:399-408. 2008
    2008 Multiple transcription start sites for FOXP2 with varying cellular specificitiesGene.  413:42-48. 2008
    2008 Mitochondrial involvement in psychiatric disordersAnnals of Medicine.  40:281-295. 2008
    2008 Failure to replicate an association of SNPs in the oxidized LDL receptor gene (OLR1) with CADBMC Medical Genetics.  9. 2008
    2008 Genome-wide admixture mapping for coronary artery calcification in African Americans: The NHLBI family heart studyGenetic Epidemiology.  32:264-272. 2008
    2008 Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets 2008
    2008 Polymorphisms within the C-Reactive Protein (CRP) Promoter Region Are Associated with Plasma CRP Levels (PII:S0002-9297(07)60902-1)American Journal of Human Genetics.  82:251. 2008
    2008 HepSEQ--an integrated hepatitis B epidemiology and sequence analysis platform.Eurosurveillance.  13. 2008
    2007 Association of polymorphisms in platelet and hemostasis system genes with acute myocardial infarctionAmerican Heart Journal.  154:1052-1058. 2007
    2007 Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: The NHLBI Family Heart Study follow-up examinationGenes and Immunity.  8:684-690. 2007
    2007 Matrix metalloproteinase circulating levels, genetic polymorphisms, and susceptibility to acute myocardial infarction among patients with coronary artery diseaseAmerican Heart Journal.  154:1043-1051. 2007
    2007 Polymorphisms in hypoxia inducible factor 1 and the initial clinical presentation of coronary diseaseAmerican Heart Journal.  154:1035-1042. 2007
    2007 Sample matching by inferred agonal stress in gene expression analyses of the brainBMC Genomics.  8. 2007
    2007 HaploBuild: An algorithm to construct non-contiguous associated haplotypes in family based genetic studiesBioinformatics.  23:2190-2192. 2007
    2007 Integrated analysis of experimental data sets reveals many novel promoters in 1% of the human genome 2007
    2007 Prominent use of distal 5′ transcription start sites and discovery of a large number of additional exons in ENCODE regions 2007
    2007 Transcription factor binding and modified histones in human bidirectional promoters 2007
    2007 Comprehensive linkage and linkage heterogeneity analysis of 4344 sibling pairs affected with hypertension from the Family Blood Pressure ProgramGenetic Epidemiology.  31:195-210. 2007
    2007 Sepiapterin reductase expression is increased in Parkinson's disease brain tissueBrain Research.  1139:42-47. 2007
    2007 Wild-type huntingtin participates in protein trafficking between the Golgi and the extracellular spaceHuman Molecular Genetics.  16:391-409. 2007
    2007 Serum response factor binding sites differ in three human cell types 2007
    2007 Evidence of QTL on 15q21 for high-density lipoprotein cholesterol: The National Heart, Lung, and Blood Institute Family Heart Study (NHLBI FHS)Atherosclerosis.  190:232-237. 2007
    2007 Genotype-by-sex interaction on fasting insulin concentration: The HyperGEN studyDiabetes.  56:137-142. 2007
    2007 LRRK2 is not a significant cause of Parkinson's disease in French-CanadiansCanadian Journal of Neurological Sciences.  34:333-335. 2007
    2007 The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onsetAnnals of Human Genetics.  71:295-301. 2007
    2006 Comparative genomics modeling of the NRSF/REST repressor network: From single conserved sites to genome-wide repertoire 2006
    2006 Genotype-by-sex interaction in the aetiology of type 2 diabetes mellitus: Support for sex-specific quantitative trait loci in Hypertension Genetic Epidemiology Network participantsDiabetologia.  49:2329-2336. 2006
    2006 Genetic analysis of the GRIK2 modifier effect in Huntington's diseaseBMC Neuroscience.  7. 2006
    2006 Adrenergic receptor polymorphisms associated with resting heart rate: The HyperGEN studyAnnals of Human Genetics.  70:566-573. 2006
    2006 Genome-wide significance for a modifier of age at neurological onset in Huntington's disease at 6q23-24: The HD MAPS studyBMC Medical Genetics.  7. 2006
    2006 Erratum: Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling (Genome Research (2006) 16, (796-803)) 2006
    2006 Assessment of automated genotyping protocols as tools for surveillance of HIV-1 genetic diversityAIDS.  20:1521-1529. 2006
    2006 Influence of heterozygosity for Parkin mutation on onset age in familial parkinson disease: The genePD studyArchives of Neurology.  63:826-832. 2006
    2006 Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in miceHuman Molecular Genetics.  15:2015-2024. 2006
    2006 Sequencing and analysis of 10,967 full-length cDNA clones from Xenopus laevis and Xenopus tropicalis reveals post-tetraploidization transcriptome remodeling 2006
    2006 Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure ProgramBMC Medical Genetics.  7. 2006
    2006 Quantitative trait loci on chromosome 8q24 for pancreatic β-cell function and 7q11 for insulin sensitivity in obese nondiabetic white and black families: Evidence from genome-wide linkage scans in the NHLBI Hypertension Genetic Epidemiology Network (HyperGEN) studyDiabetes.  55:551-558. 2006
    2006 Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genome 2006
    2006 Considerations for genomewide association studies in Parkinson disease [1]American Journal of Human Genetics.  78:1081-1082. 2006
    2006 Genotyping hepatitis B virus from whole- and sub-genomic fragments using position-specific scoring matrices in HBV STARJournal of General Virology.  87:1459-1464. 2006
    2005 HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolismHuman Molecular Genetics.  14:2871-2880. 2005
    2005 A statistical model for HIV-1 sequence classification using the subtype analyser (STAR)Bioinformatics.  21:3535-3540. 2005
    2005 A haplotype similarity based transmission/disequilibrium test under founder heterogeneityAnnals of Human Genetics.  69:455-467. 2005
    2005 Direct isolation and identification of promoters in the human genome 2005
    2005 Monozygotic twins discordant for Huntington disease after 7 yearsArchives of Neurology.  62:995-997. 2005
    2005 Variability and conservation in hepatitis B virus core proteinBMC Microbiology.  5. 2005
    2005 Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsinsFEBS Letters.  579:2149-2155. 2005
    2005 Linkage of the cholesterol 7α-hydroxylase gene and low-density lipoprotein cholesterol conditional on apolipoprotein E association: The National Heart, Lung, and Blood Institute Family Heart StudyChinese Medical Journal.  118:362-369. 2005
    2005 Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levelsAmerican Journal of Human Genetics.  77:64-77. 2005
    2004 Coelacanth genome sequence reveals the evolutionary history of vertebrate genes 2004
    2004 Genome-wide linkage analyses for age at diagnosis of hypertension and early-onset hypertension in the HyperGEN studyAmerican Journal of Hypertension.  17:839-844. 2004
    2004 The master sex-determination locus in threespine sticklebacks is on a nascent Y chromosomeCurrent Biology.  14:1416-1424. 2004
    2004 Lack of Evidence for An Association between WNT2 and RELN Polymorphisms and AuitismAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  126 B:51-57. 2004
    2004 Systematic changes in gene expression in postmortem human brains associated with tissue pH and terminal medical conditionsHuman Molecular Genetics.  13:609-616. 2004
    2004 Genome-Wide Scan Identifies Novel QTLs for Cholesterol and LDL Levels in F2[Dahl RxS] Intercross RatsCirculation Research.  94:446-452. 2004
    2004 Gene conversion and the evolution of protocadherin gene cluster diversity 2004
    2004 Transcriptional regulation and binding of heat shock factor 1 and heat shock factor 2 to 32 human heat shock genes during thermal stress and differentiationCell Stress and Chaperones.  9:21-28. 2004
    2004 Effect of agonal and postmortem factors on gene expression profile: Quality control in microarray analyses of postmortem human brainBiological Psychiatry.  55:346-352. 2004
    2004 Selective Disruption of Lysosomes in HeLa Cells Triggers Apoptosis Mediated by Cleavage of Bid by Multiple Papain-like Lysosomal CathepsinsJournal of Biological Chemistry.  279:3578-3587. 2004
    2004 An abundance of bidirectional promoters in the human genome 2004
    2004 Apolipoprotein E polymorphism modifies the alcohol-HDL association observed in the National Heart, Lung, and Blood Institute Family Heart StudyAmerican Journal of Clinical Nutrition.  80:1639-1644. 2004
    2004 Common variants in the 5′ region of the leptin gene are associated with body mass index in men from the National Heart, Lung, and Blood Institute Family Heart StudyAmerican Journal of Human Genetics.  75:220-230. 2004
    2004 Development of a novel human immunodeficiency virus type 1 subtyping tool, subtype analyzer (STAR): Analysis of subtype distribution in LondonAIDS Research and Human Retroviruses.  20:457-464. 2004
    2004 Linkage analysis of diabetes status among hypertensive families: The hypertension genetc epidemiology network studyDiabetes.  53:3307-3312. 2004
    2004 The status, quality, and expansion of the NIH full-length cDNA project: The Mammalian Gene Collection (MGC) 2004
    2003 Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1)Cell Death and Differentiation.  10:1329-1335. 2003
    2003 A genome-wide scan for loci affecting normal adult height in the Framingham Heart Study 2003
    2003 Linkage Analysis of a Composite Factor for the Multiple Metabolic Syndrome: The National Heart, Lung, and Blood Institute Family Heart StudyDiabetes.  52:2840-2847. 2003
    2003 Linkage and association with pulmonary function measures on chromosome 6q27 in the Framingham Heart StudyHuman Molecular Genetics.  12:2745-2751. 2003
    2003 A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS studyAmerican Journal of Human Genetics.  73:682-687. 2003
    2003 Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1) 2003
    2003 Identification of promoter regions in the human genome by using a retroviral plasmid library-based functional reporter gene assay 2003
    2003 Interaction of normal and expanded CAG repeat sizes influences age at onset of Huntington disease 2003
    2003 A Genome-Wide Scan of Pulmonary Function Measures in the National Heart, Lung, and Blood Institute Family Heart StudyAmerican Journal of Respiratory and Critical Care Medicine.  167:1528-1533. 2003
    2003 A genome scan for loci linked to quantitative insulin traits in persons without diabetes: The Framingham Offspring StudyDiabetologia.  46:579-587. 2003
    2003 Microarray technology: A review of new strategies to discover candidate vulnerability genes in psychiatric disordersAmerican Journal of Psychiatry.  160:657-666. 2003
    2003 Combined analysis of genomewide scans for adult height: Results from the NHLBI family blood pressure programEuropean Journal of Human Genetics.  11:271-274. 2003
    2003 Extensive linkage disequilibrium, a common 16.7-kilobase deletion, and evidence of balancing selection in the human protocadherin α clusterAmerican Journal of Human Genetics.  72:621-635. 2003
    2003 Genomewide linkage analysis to presbycusis in the Framingham Heart Study 2003
    2003 Identification and functional analysis of human transcriptional promoters 2003
    2003 Rabbit endogenous retrovirus-H encodes a functional proteaseJournal of General Virology.  84:215-225. 2003
    2002 Is DFNA5 a susceptibility gene for age-related hearing impairment?European Journal of Human Genetics.  10:883-886. 2002
    2002 Rapid mapping of zebrafish mutations with SNPs and oligonucleotide microarrays 2002
    2002 A genome-wide screen reveals evidence for a locus on chromosome 11 influencing variation in LDL cholesterol in the NHLBI Family Heart StudyHuman Genetics.  111:263-269. 2002
    2002 Evidence for a gene influencing heart rate on chromosome 4 among hypertensivesHuman Genetics.  111:207-213. 2002
    2002 Segregation analysis of Parkinson disease revealing evidence for a major causative gene 2002
    2002 Genome scan for quantity of hand osteoarthritis: The Framingham StudyArthritis and Rheumatism.  46:946-952. 2002
    2002 Genetic loci influencing lung function: A genomewide scan in the Framingham StudyAmerican Journal of Respiratory and Critical Care Medicine.  165:795-799. 2002
    2002 Behavioral phenotypic variation in autism multiplex families: Evidence for a continuous severity gradientAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  114:129-136. 2002
    2002 Lack of association between HoxA1 and HoxB1 gene variants and autism in 110 multiplex familiesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  114:24-30. 2002
    2002 A genome-wide scan for loci linked to plasma levels of glucose and HbA1c in a community-based sample of Caucasian pedigrees: The Framingham Offspring StudyDiabetes.  51:833-840. 2002
    2002 Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: The Framingham studyJournal of Bone and Mineral Research.  17:1718-1727. 2002
    2002 PARK3 influences age at onset in Parkinson disease: A genome scan in the GenePD studyAmerican Journal of Human Genetics.  70:1089-1095. 2002
    2002 Quantitative-trait loci influencing body-mass index reside on chromosomes 7 and 13: The National Heart, Lung, and Blood Institute Family Heart StudyAmerican Journal of Human Genetics.  70:72-82. 2002
    2001 Heritability of longitudinal change in lung function: The Framingham studyAmerican Journal of Respiratory and Critical Care Medicine.  164:1655-1659. 2001
    2001 Birth Order Effects on Nonverbal IQ Scores in Autism Multiplex FamiliesJournal of Autism and Developmental Disorders.  31:449-460. 2001
    2001 Cystatin B-deficient mice have increased expression of apoptosis and glial activation genesHuman Molecular Genetics.  10:1867-1871. 2001
    2001 A dose-ranging study to evaluate the antiretroviral activity and safety of amprenavir alone and in combination with abacavir in HIV-infected adults with limited antiretroviral experienceAntiviral Therapy.  6:89-96. 2001
    2001 Genetic and environmental contributions to platelet aggregation: The Framingham Heart StudyCirculation.  103:3051-3056. 2001
    2001 Comparative DNA sequence analysis of mouse and human protocadherin gene clusters [3] 2001
    2001 Association of plasma bilirubin with coronary heart disease and segregation of bilirubin as a major gene trait: The NHLBI family heart studyAtherosclerosis.  154:747-754. 2001
    2001 Genome scan for quantitative trait loci linked to high-density lipoprotein cholesterol: The NHLBI Family Heart Study 2001
    2001 Genome-wide linkage analysis of lipids in the hypertension genetic epidemiology network (HyperGEN) blood pressure study 2001
    2001 Interaction of α1-Na,K-ATPase and Na,K,2Cl-cotransporter genes in human essential hypertensionHypertension.  38:204-209. 2001
    2001 Quantitative neuropathological changes in presymptomatic Huntington's diseaseAnnals of Neurology.  49:29-34. 2001
    2000 Absence of linkage for bone mineral density to chromosome 12q12-14 in the region of the vitamin D receptor geneCalcified Tissue International.  67:434-439. 2000
    2000 HIV type 1 protease cleavage site mutations and viral fitness: Implications for drug susceptibility phenotyping assaysAIDS Research and Human Retroviruses.  16:1149-1156. 2000
    2000 Evidence for major genes influencing pulmonary function in the NHLBI Family Heart StudyGenetic Epidemiology.  19:81-94. 2000
    2000 Evidence for a gene influencing the TG/HDL-C ratio on chromosome 7q32.3-qter: A genome-wide scan in the Framingham StudyHuman Molecular Genetics.  9:1315-1320. 2000
    2000 Segregation analysis of serum uric acid in the NHLBI Family Heart StudyHuman Genetics.  106:355-359. 2000
    2000 Insulin and hypertension in the NHLBI family heart studyAmerican Journal of Hypertension.  13:240-250. 2000
    2000 Evidence for a gene influencing blood pressure on chromosome 17: Genome scan linkage results for longitudinal blood pressure phenotypes in subjects from the Framingham Heart StudyHypertension.  36:477-483. 2000
    2000 Replication of linkage of familial combined hyperlipidemia to chromosome 1q with additional heterogeneous effect of apolipoprotein A-I/C-III/A-IV locus: The NHLBI family heart study 2000
    2000 Resistance to the HIV protease inhibitor amprenavir in vitro and in clinical studies: A reviewClinical Drug Investigation.  20:267-285. 2000
    1999 Environmental, medical, and family history risk factors for Parkinson's disease: A new England-based case control studyAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  88:742-749. 1999
    1999 Parental age at child's birth and son's risk of prostate cancer. The Framingham StudyAmerican Journal of Epidemiology.  150:1208-1212. 1999
    1999 Effects of similarities in lifestyle habits on familial aggregation of high density lipoprotein and low density lipoprotein cholesterol: The NHLBI Family Heart StudyAmerican Journal of Epidemiology.  150:910-918. 1999
    1999 Absence of linkage and linkage disequilibrium to chromosome 15q11-q13 markers in 139 multiplex families with autismAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics.  88:551-556. 1999
    1999 A putative Drosophila homolog of the Huntington's disease geneHuman Molecular Genetics.  8:1807-1815. 1999
    1999 Evidence for a major gene accounting for mild elevation in LDL cholesterol: The NHLBI Family Heart StudyAnnals of Human Genetics.  63:401-412. 1999
    1999 Evaluation of biomarker modulation by fenretinide in prostate cancer patientsEuropean Urology.  35:429-438. 1999
    1999 Lewis blood group phenotype as an independent risk factor for coronary heart disease (the NHLBI Family Heart Study)American Journal of Cardiology.  83:345-348. 1999
    1999 A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in miceHuman Molecular Genetics.  8:763-774. 1999
    1999 A genomic screen of autism: Evidence for a multilocus etiologyAmerican Journal of Human Genetics.  65:493-507. 1999
    1999 Exclusion of linkage to the HLA region in ninety multiplex sibships with autismJournal of Autism and Developmental Disorders.  29:195-201. 1999
    1999 Impaired synaptic plasticity in mice carrying the Huntington's disease mutationHuman Molecular Genetics.  8:839-846. 1999
    1999 Increased platelet aggregability associated with platelet GPIIIa Pl(A2) polymorphism: The Framingham offspring study 1999
    1999 The molecular genetic bases of the progressive myoclonus epilepsies. 1999
    1998 Characterization of the Huntington's disease (HD) gene homolog in the zebrafish Danio rerioGene.  217:117-125. 1998
    1998 Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: The Framingham StudyArthritis and Rheumatism.  41:1064-1071. 1998
    1998 Evidence for association and genetic linkage of the angiotensin- converting enzyme locus with hypertension and blood pressure in men but not women in the Framingham Heart StudyCirculation.  97. 1998
    1998 Effects of age and ethnicity on the link between apoe ε4 and Alzheimer disease [2] (multiple letters) 1998
    1998 Angiotensinogen and angiotensin converting enzyme genotypes and carotid atherosclerosis: The atherosclerosis risk in communities and the NHLBI family heart studiesAtherosclerosis.  138:111-116. 1998
    1998 On the pathological progression of Huntington's disease [1] (multiple letters)Annals of Neurology.  44:148. 1998
    1998 Segregation analysis of pulmonary function among families in the framingham studyAmerican Journal of Respiratory and Critical Care Medicine.  157:1445-1451. 1998
    1997 Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: A meta-analysis 1997
    1997 Identification and characterization of the human homologue of SH3BP2, an SH3 binding domain protein within a common region of deletion at 4p16.3 Involved in bladder cancerGenomics.  44:163-170. 1997
    1997 The BsmI vitamin D receptor restriction fragment length polymorphism (bb) influences the effect of calcium intake on bone mineral densityJournal of Bone and Mineral Research.  12:1049-1057. 1997
    1997 Long-term impact of Huntington disease linkage testing 1997
    1997 CAG repeat number governs the development rate of pathology in huntington's diseaseAnnals of Neurology.  41:689-692. 1997
    1997 An STS-based radiation hybrid map of the human genome 1997
    1997 Heritability of left ventricular mass: The Framingham Heart StudyHypertension.  30:1025-1028. 1997
    1997 High-resolution physical and transcriptional mapping of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy locus on chromosome 21q22.3 by FISH 1997
    1997 Reduced penetrance of the Huntington's disease mutationHuman Molecular Genetics.  6:775-779. 1997
    1996 Human immunodeficiency virus: Mutations in the viral protease that confer resistance to saquinavir increase the dissociation rate constant of the protease-saquinavir complexJournal of Biological Chemistry.  271:33231-33235. 1996
    1996 Fluorescence in situ hybridization deletion mapping at 4p16.3 in bladder cancer cell lines refines the localisation of the critical interval to 30 kb 1996
    1996 Progressive myoclonus epilepsy EPM1 locus maps to a 175-kb interval in distal 21qAmerican Journal of Human Genetics.  58:1247-1253. 1996
    1996 Incomplete dominance of type III hyperlipoproteinemia is associated with the rare apolipoprotein E2 (Arg136 → Ser) variant in multigenerational pedigree studiesAtherosclerosis.  122:33-46. 1996
    1996 Construction of a 750-kb bacterial clone contig and restriction map in the region of human chromosome 21 containing the progressive myoclonus epilepsy gene 1996
    1996 Genomes and evolutionCurrent Opinion in Genetics and Development.  6:683-685. 1996
    1996 Isolation and characterization of the mouse cystatin B gene 1996
    1996 The end of the beginning: the race to begin human genome sequencing. 1996
    1995 Statement on use of apolipoprotein E testing for Alzheimer disease 1995
    1995 Evidence from antibody studies that the CAG repeat in the huntington disease gene is expressed in the proteinHuman Molecular Genetics.  4:465-469. 1995
    1995 Cross-resistance analysis of human immunodeficiency virus type 1 variants individually selected for resistance to five different protease inhibitorsAntimicrobial Agents and Chemotherapy.  39:1704-1710. 1995
    1994 Localization of the α2-Macroglobulin Receptor-Associated Protein 1 Gene (LRPAP1) and Other Gene Fragments to Human Chromosome 4p16.3 by Direct cDNA SelectionGenomics.  24:410-413. 1994
    1994 A high resolution physical map of 2.5 Mbp of the down syndrome region on chromosome 21Human Molecular Genetics.  3:1811-1817. 1994
    1994 A transcript map of the down syndrome critical region on chromosome 21Human Molecular Genetics.  3:1735-1742. 1994
    1994 Identification of genes within CpG-enriched DNA from human chromosome 4p16.3Human Molecular Genetics.  3:1611-1616. 1994
    1994 Isolation of yeast artificial chromosome clones from 54 polymorphic loci mapped with high odds on human chromosome 4Human Molecular Genetics.  3:243-246. 1994
    1994 Apolipoprotein E Alleles, Dyslipidemia, and Coronary Heart Disease: The Framingham Offspring Study 1994
    1994 Neocortical Dendritic Pathology in Human Partial Epilepsy: A Quantitative Golgi StudyEpilepsia.  35:728-736. 1994
    1994 Report of the third international workshop on human chromosome 4 mapping 1993 1994
    1993 The development of sequence-tagged sites for human chromosome 4Human Molecular Genetics.  2:1271-1288. 1993
    1993 Construction of cosmid contigs and high-resolution restriction mapping of the huntington disease region of human chromosome 4Human Molecular Genetics.  2:889-899. 1993
    1993 A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomesCell.  72:971-983. 1993
    1993 A radiation hybrid map of the distal short arm of human chromosome 11, containing the Beckwith-Weidemann and associated embryonal tumor disease lociAmerican Journal of Human Genetics.  52:915-921. 1993
    1993 Segregation analysis for high density lipoprotein in the berkeley dataGenetic Epidemiology.  10:629-634. 1993
    1993 The normal Huntington disease (HD) allele, or a closely linked gene, influences age at onset of HDAmerican Journal of Human Genetics.  53:125-130. 1993
    1992 Cloning of the huntington disease region in yeast artificial chromosomesHuman Molecular Genetics.  1:149-159. 1992
    1992 Genetic linkage analysis of bipolar affective disorder in an Old Order Amish pedigreeHuman Genetics.  88:562-568. 1992
    1992 A radiation hybrid map of the region on human chromosome 22 containing the neurofibromatosis type 2 locusGenomics.  14:574-584. 1992
    1992 A simple and efficient method for attachment of a 40-base pair, GC-rich sequence to PCR-amplified DNA 1992
    1992 Bridging the gapsCurrent Biology.  2:338-339. 1992
    1992 Does the omission of missing information bias the estimates of age-at- onset distributions? [5]American Journal of Human Genetics.  50:652-654. 1992
    1992 Evidence of presymptomatic cognitive decline in Huntington's diseaseJournal of Clinical and Experimental Neuropsychology.  14:961-975. 1992
    1992 Familial lipoprotein disorders in patients with premature coronary artery diseaseCirculation.  85:2025-2033. 1992
    1992 Family patterns of coronary heart disease mortality: The Framingham Longevity StudyJournal of Clinical Epidemiology.  45:169-174. 1992
    1992 Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprintingAmerican Journal of Human Genetics.  50:528-535. 1992
    1992 Recombination of 4p16 DNA markers in an unusual family with Huntington diseaseAmerican Journal of Human Genetics.  50:1218-1230. 1992
    1992 Segregation analysis in Alzheimer disease: No evidence for a major gene [2]American Journal of Human Genetics.  50:645-648. 1992
    1991 A radiation hybrid map of the proximal long arm of human chromosome 11 containing the multiple endocrine neoplasia type 1 (MEN-1) and bcl-1 disease lociAmerican Journal of Human Genetics.  49:1189-1196. 1991
    1991 Segregation analysis reveals evidence of a major gene for Alzheimer diseaseAmerican Journal of Human Genetics.  48:1026-1033. 1991
    1991 A map of the distal region of the long arm of human chromosome 21 constructed by radiation hybrid mapping and pulsed-field gel electrophoresisGenomics.  9:19-30. 1991
    1991 Cerebral amyloid angiopathy without and with cerebral hemorrhages: A comparative histological studyAnnals of Neurology.  30:637-649. 1991
    1991 Estimation of morbid risk and age at onset with missing informationAmerican Journal of Human Genetics.  49:76-87. 1991
    1991 Factors Associated With Slow Progression in Huntington's DiseaseArchives of Neurology.  48:800-804. 1991
    1991 Invited editorial: The end in sight for Huntington disease?American Journal of Human Genetics.  49:1-6. 1991
    1991 Physical mapping of yeast artificial chromosomes containing sequences from the human β-globin gene regionGenomics.  10:976-984. 1991
    1991 Understanding the decision to take the predictive test for Huntington disease 1991
    1990 Analysis of the site in CD4 that binds to the HIV envelope glycoproteinJournal of Immunology.  144:3078-3086. 1990
    1990 Estimation of familial risk in Alzheimer's diseaseAnnals of Neurology.  27:338-340. 1990
    1990 Parental history is an independent risk factor for coronary artery disease: The Framingham StudyAmerican Heart Journal.  120:963-969. 1990
    1990 ReplyAnnals of Neurology.  27:340-341. 1990
    1989 Coronary risk associated with age and sex of parental heart disease in the Framingham StudyAmerican Journal of Cardiology.  64:555-559. 1989
    1989 Methylation at the Huntington disease-linked D4S95 locus.American Journal of Human Genetics.  45:335-336. 1989
    1989 Assessment of genetic risk for alzheimer's disease among first‐degree relativesAnnals of Neurology.  25:485-493. 1989
    1989 Clustering of multiallele DNA markers near the Huntington's disease geneJournal of Clinical Investigation.  84:1013-1016. 1989
    1989 Estimation of fertility and fitness in Huntington disease in New England 1989
    1989 Homozygote for Huntington diseaseAmerican Journal of Human Genetics.  45:615-618. 1989
    1989 Huntington disease: No evidence for locus heterogeneityGenomics.  5:304-308. 1989
    1989 Isolation and field-inversion gel electrophoresis analysis of DNA markers located close to the Huntington disease geneGenomics.  4:408-418. 1989
    1989 Molecular Genetics of Familial Alzheimer's DiseaseCanadian Journal of Neurological Sciences.  16:465-467. 1989
    1989 Molecular genetics of familial alzheimer’s diseaseEuropean Neurology.  29:25-27. 1989
    1989 Segregation of the Huntington disease region of human chromosome 4 in a somatic cell hybridGenomics.  4:397-407. 1989
    1989 Using survival methods to estimate age-at-onset distributions for genetic diseases with an application to Huntington diseaseGenetic Epidemiology.  6:361-371. 1989
    1987 Attitudes toward presymptomatic testing in Huntington disease 1987
    1986 Change in attitudes toward presymptomatic testing in Huntington disease 1986
    1986 Recent advances in the development of methods for detecting single-base substitutions associated with human genetic diseases 1986
    1985 Maternal factors in onset of Huntington diseaseAmerican Journal of Human Genetics.  37:511-523. 1985
    1984 Potential impact of a predictive test on the gene frequency of Huntington disease 1984
    1982 Alzheimer's Disease, Down's Syndrome, and Aging: The Genetic ApproachAnnals of the New York Academy of Sciences.  396:3-13. 1982
    1982 Factors related to onset age of Huntington diseaseAmerican Journal of Human Genetics.  34:481-488. 1982
    1981 Does simian virus 40 T antigen unwind DNA?Journal of Biological Chemistry.  256:10156-10160. 1981
    1981 SV40 gene expression is modulated by the cooperative binding of T antigen to DNACell.  25:373-384. 1981
    1980 Characteristics of a Gibbon-Siamang hybrid apeInternational Journal of Primatology.  1:203-221. 1980
    1979 Quantification of muscle tremor of Huntington's disease patients and their offspring in an early detection studyBiological Psychiatry.  14:777-789. 1979


    Year Title Altmetric
    2016 Advancements in Next-Generation Sequencing.  Ed. 17.  2016


    Year Title Altmetric
    2020 Epitope tagging ChIP-seq of DNA binding proteins using CETCh-seq.  3-34. 2020
    2016 Huntington’s disease.  503-516. 2016
    2015 Mutation detection by PCR, GC-ciamps, and denaturing gradient gel electrophoresis.  71-88. 2015
    2008 The fibroblast growth factor family and mood disorders. 2008

    Education And Training

  • Doctor of Philosophy in Biochemistry, University of California System : Berkeley 1982
  • Bachelor of Science or Mathematics, University of Alabama 1977
  • Full Name

  • Richard Myers