Positions

Selected Publications

Academic Article

Year Title Altmetric
2018 Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells 2018
2018 IL-1R signaling promotes STAT3 and NF-B factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription 2018
2015 IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iT reg cell balance 2015
2014 Deletion of a Conserved cis-Element in the Ifng Locus Highlights the Role of Acute Histone Acetylation in Modulating Inducible Gene Transcription 2014
2013 Notch Simultaneously Orchestrates Multiple Helper T Cell Programs Independently of Cytokine Signals 2013
2013 The Th17 family: Flexibility follows function 2013
2012 Th22 Cells Are an Important Source of IL-22 for Host Protection against Enteropathogenic Bacteria 2012
2012 Reciprocal interactions of the intestinal microbiota and immune system 2012
2011 TGF-β in Th17 cell development: The truth is out there 2011
2010 Regulation of the Ifng locus in the context of T-lineage specification and plasticity 2010
2010 Modular utilization of distal cis-regulatory elements controls Ifng gene expression in T cells activated by distinct stimuli 2010
2010 Epigenetic instability of cytokine and transcription factor gene loci underlies plasticity of the T helper 17 cell lineage 2010
2009 Interplay between the TH 17 and TReg cell lineages: A (co-)evolutionary perspective 2009
2009 The AP-1 transcription factor Batf controls T H 17 differentiation 2009
2009 Developmental plasticity of Th17 and Treg cells 2009
2009 Contrasting roles for all-trans retinoic acid in TGF-β-mediated induction of Foxp3 and Il10 genes in developing regulatory T cells 2009
2009 Duality in the Th17-Treg developmental decision. 2009
2007 IL-17 family cytokines and the expanding diversity of effector T cell lineages 2007
2006 A Distal Conserved Sequence Element Controls Ifng Gene Expression by T Cells and NK Cells 2006
2006 Transforming growth factor-β induces development of the T H17 lineage 2006
2005 Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages 2005
2005 Generation of antigen-specific, Foxp3-expressing CD4+ regulatory T cells by inhibition of APC proteosome function 2005
2004 Regulatory T cell suppression and anergy are differentially regulated by proinflammatory cytokines produced by TLR-activated dendritic cells 2004
2003 T-bet or Not T-bet 2003
2002 Gene delivery into primary T cells: Overview and characterization of a transgenic model for efficient adenoviral transduction 2002
2002 Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model 2002
2002 Efficient adenovirus-mediated gene transfer into primary T cells and thymocytes in a new coxsackie/adenovirus receptor transgenic model. 2002
2001 Differential expression of Fas ligand in Th1 and Th2 cells is regulated by early growth response gene and NF-AT family members 2001

Investigator On

  • Specialization of Innate and Adaptive Immune Cells in Intestinal Barrier Function  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2017 - 2022
  • Mechanisms Controlling Regulatory T Cell Effector Function in IBD  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2017 - 2021
  • Private Grant  awarded by JT PHARMA INC. 2017 - 2020
  • Th17 Pathway Plasticity in the Pathogenesis of Inflammatory Bowel Disease  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2019
  • Molecular Regulation of MS Susceptibility Genes  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2013 - 2018
  • Factors Controlling Effector T Cell Maintenance in the Pathogenesis of Colitis  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2011 - 2017
  • Gene Regulatory Networks Controlling Effector and Regulatory T Cell Balance in IBD  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2015 - 2016
  • Innate and Adaptive Immunity in IBD  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2016
  • Innate and Adaptive Immunity in IBD - Project 3  awarded by National Institute of Diabetes and Digestive and Kidney Diseases/NIH/DHHS 2010 - 2016
  • Control of Chromatin Landscapes in Effector T Cell Lineage Specifications  awarded by National Institute of Allergy and Infectious Diseases/NIH/DHHS 2009 - 2014
  • Full Name

  • Robin Hatton