Androgen metabolism in somatic and germinal tissues of the sea star Asterias vulgaris

Academic Article

Abstract

  • 1. 1. Cell-free homogenates of male and female pyloric caeca, body wall, testis and ovary were incubated with radiolabeled 3H-androstenedione. 2. 2. Pyloric caeca had highest rates of androstenedione conversion. The predoimannt metabolites in the pyloric caeca were testosterone, 5α-andostane-3β,17β-diol and 5β-andostane-3β,17β-diol. 3. 3. In body wall, testicular and ovarian homogenates, androstenedione was converted primarily to testosterone and also to 5α-andostanedione and epiandrosterone. 4. 4. Qualitative and quantitative differences in androgen metabolism in somatic and germinal tissuesmay be related to tissue-specific regulation of cellular metabolism. © 1992.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Hines GA; Watts SA; Walker CW; Voogt PA
  • Start Page

  • 521
  • End Page

  • 526
  • Volume

  • 102
  • Issue

  • 3