Bypassing V1: A direct geniculate input to area MT

Academic Article

Abstract

  • Thalamic nuclei are thought to funnel sensory information to the brain's primary cortical areas, which in turn transmit signals afresh to higher cortical areas. Here we describe a direct projection in the macaque monkey from the lateral geniculate nucleus (LGN) to the motion-selective middle temporal area (MT or V5), a cortical area not previously considered 'primary'. The constituent neurons are mostly koniocellular, send virtually no collateral axons to primary visual cortex (V1) and equal about 10% of the V1 population innervating MT. This pathway could explain the persistence of motion sensitivity in subjects following injury to V1, suggesting more generally that residual perception after damage in a primary area may arise from sparse thalamic input to 'secondary' cortical areas.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Sincich LC; Park KF; Wohlgemuth MJ; Horton JC
  • Start Page

  • 1123
  • End Page

  • 1128
  • Volume

  • 7
  • Issue

  • 10