Concentration calibration of urine biomarkers for diagnosis improvement of ovarian cancer

Academic Article


  • This paper investigates the calibration effect of urine biomarkers by creatinine. The biomarkers were obtained from each urine sample of 256 patients (cancer: 137, benign: 119). The logistic regression of the combinations of 2 biomarkers calibrated by creatinine concentration was compared with that of the 3 biomarkers including creatinine. The average AUC over 1000 rounds of 5-fold cross validations was employed to evaluate the performance. The logistic regression of the calibrated biomarkers showed better performance than that without calibration for the top- ranked combinations. © 2014 SERSC.
  • Digital Object Identifier (doi)

    Author List

  • Yang ES; Kim YS; Park CY; Song HJ; Kim JD
  • Start Page

  • 65
  • End Page

  • 72
  • Volume

  • 6
  • Issue

  • 1