Complete heart block in association with graft-versus-host disease

Academic Article


  • An infant who received haploidentical BM for severe combined immunodeficiency (SCID) developed acute, reversible complete heart block in association with an exacerbation of GVHD. Respiratory distress and myocardial dysfunction were also seen with this and previous GVHD exacerbations. The patient had not received chemotherapy or radiation prior to BMT. The complete heart block resolved after 1 week of intensive immunosuppression. The association of complete heart block with GVHD is important because the heart block is potentially reversible with prompt, aggressive control of the GVHD.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Gilman AL; Kooy NW; Atkins DL; Ballas Z; Rumelhart S; Holida M; Lee N; Goldman F
  • Start Page

  • 85
  • End Page

  • 88
  • Volume

  • 21
  • Issue

  • 1