This study's purpose was to determine whether albuterol administration changed time course adaptations to strength gain in persons undergoing resistance exercise. Study treatments were randomized and double blinded. Subjects performed 3 maximal sets of 10 repetitions of isokinetic knee extensions with coupled concentric-eccentric contractions at 45° · sec-1 twice a week for 9 weeks. Full placebo (n = 9) and albuterol (n = 13) (16 mg a day) administration began at Week 3. Repeated measures 2 × 9 MANOVA and a priori planned comparisons revealed statistical significance for 10 strength variables. Four variables showed a time effect. Interactions were noted for 6 variables, with subjects given albuterol displaying superior values. Results indicate that training with albuterol hastened time course changes in strength gain compared to training with a placebo. Albuterol and isokinetic exercise may hasten the reacquisition of strength in persons who have been ill or injured. © 1997 National Strength & Conditioning Association.