Cancer gene therapy

Chapter

Abstract

  • Cancer is the product of a multi-step process involving an accumulation of genetic alterations in somatic cells [203]. Advances in the understanding of the molecular basis of neoplasia and host-tumor relationships have resulted in new cancer therapy strategies with translation into clinical trials. Gene therapy has emerged as a treatment strategy which relies on the introduction of genetic material to cure, slow the progression, or possibly even prevent a variety of diseases including genetic, infectious (HIV in particular), cardiovascular, and arthritic diseases [11, 66]. Gene therapy has shown potential for the treatment of cancer. A number of cancer gene therapy approaches have been developed based on direct correction of genetic lesions. © Springer Science+Business Media B.V. 2009.
  • Digital Object Identifier (doi)

    International Standard Book Number (isbn) 13

  • 9789048122776
  • Start Page

  • 589
  • End Page

  • 612