© 2014, © The Author(s) 2014. Purpose: This study evaluated a culturally relevant, social cognitive theory–based, Internet-enhanced physical activity (PA) pilot intervention developed for overweight/obese African American (AA) female college students. Design: Using a 3-month, single group, pretest–posttest design, participants accessed a culturally relevant PA promotion website and engaged in four moderate-intensity PA sessions each week. Results: Study completers (n = 25, mean age = 21.9 years) reported a decrease in sedentary screen time (p <.0001); however, no changes in moderate-to-vigorous PA were reported (p =.150). A significant increase in self-regulation for PA (p <.0001) and marginally significant increases in social support (p =.052) and outcome expectations (p =.057) for PA were observed. No changes in body mass index (p =.162), PA enjoyment (p =.151), or exercise self-efficacy (p =.086) were reported. Conclusions: Findings of this exploratory study show some preliminary support for Internet-enhanced approaches to promote PA among overweight/obese AA women. Implications for Practice: Future studies with larger samples are needed to further explore culturally relevant Internet-enhanced PA programs in this underserved population.