Retinoids and epigenetic silencing in cancer

Academic Article

Abstract

  • An epigenetic event alters the activity of genes without changing their structure. Methylation reactions are important mediators of epigenetic events in cells. Two recent studies have established a mechanistic link between a vitamin A metabolite and epigenetic alterations of its target promoter that could provide insights about the role of vitamin A in cancer prevention. © 2003 International Life Sciences Institute.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 14985196
  • Author List

  • Johanning GL; Piyathilake CJ
  • Start Page

  • 284
  • End Page

  • 289
  • Volume

  • 61
  • Issue

  • 8