Ivy/neurogliaform interneurons coordinate activity in the neurogenic niche

Academic Article

Abstract

  • Depolarization by the neurotransmitter GABA regulates adult neurogenesis. We found interneurons of the neurogliaform cell family to be a primary source of GABA for newborn neurons in mouse dentate gyrus. GABAergic depolarization occurred in concert with reduced synaptic inhibition of mature neurons, suggesting that the local circuitry coordinates the activation of new and pre-existing cells. © 2011 Nature America, Inc. All rights reserved.
  • Published In

  • jrnl6234  Journal
  • Digital Object Identifier (doi)

    Start Page

  • 1407
  • End Page

  • 1409
  • Volume

  • 14