Models of astrocytic Ca2+ dynamics and epilepsy

Academic Article


  • Neurons have been the focus of neuroscience research. Only recently, however, astrocytes, a subset of glial cells, have been on the neurobiology 'radar' owing to their Ca2+ excitability, which allows them to signal to other astrocytes and neurons. This review summarizes the models for studying astrocytic Ca2+ dynamics and the consequential Ca2+-dependent glutamate release, which plays a role in astrocytic-neuronal signaling and have been implicated in epilepsy. © 2008 Elsevier Ltd. All rights reserved.
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    Digital Object Identifier (doi)

    Author List

  • Reyes RC; Parpura V
  • Start Page

  • 13
  • End Page

  • 18
  • Volume

  • 5
  • Issue

  • 1