Water soluble single-walled carbon nanotubes inhibit stimulated endocytosis in neurons

Academic Article

Abstract

  • We report the use of chemically functionalized water soluble single-walled carbon nanotube (SWNT) graft copolymers to inhibit endocytosis. The graft copolymers were prepared by the functionalization of SWNTs with polyethylene glycol. When added to the culturing medium, these functionalized water soluble SWNTs were able to increase the length of various neuronal processes, neurites, as previously reported. Here we have determined that SWNTs are able to block stimulated membrane endocytosis in neurons, which could then explain the previously noted extended neurite length. © 2008 American Chemical Society.
  • Published In

  • Nano Letters  Journal
  • Digital Object Identifier (doi)

    Author List

  • Malarkey EB; Reyes RC; Zhao B; Haddon RC; Parpura V
  • Start Page

  • 3538
  • End Page

  • 3542
  • Volume

  • 8
  • Issue

  • 10