Chemically functionalized water-soluble single-walled carbon nanotubes modulate morpho-functional characteristics of astrocytes

Academic Article

Abstract

  • We report the use of chemically functionalized water-soluble single-walled carbon nanotubes (ws-SWCNTs) for the modulation of morpho-functional characteristics of astrocytes. When added to the culturing medium, ws-SWCNTs were able to make astrocytes larger and stellate/mature, changes associated with the increase in glial fibrillary acidic protein immunoreactivity. Thus, ws-SWCNTs could have more beneficial effects at the injury site than previously thought; by affecting astrocytes, they could provide for a more comprehensive re-establishment of the brain computational power. © 2012 American Chemical Society.
  • Published In

  • Nano Letters  Journal
  • Digital Object Identifier (doi)

    Author List

  • Gottipati MK; Kalinina I; Bekyarova E; Haddon RC; Parpura V
  • Start Page

  • 4742
  • End Page

  • 4747
  • Volume

  • 12
  • Issue

  • 9