Chemically functionalized single-walled carbon nanotube films modulate the morpho-functional and proliferative characteristics of astrocytes

Academic Article

Abstract

  • We used single-walled carbon nanotube (CNT) films to modulate the morpho-functional and proliferative characteristics of astrocytes. When plated on the CNT films of various thicknesses, astrocytes grow bigger and rounder in shape with a decrease in the immunoreactivity of glial fibrillary acidic protein along with an increase in their proliferation, changes associated with the dedifferentiation of astrocytes in culture. Thus, CNT films, as a coating material for electrodes used in brain machine interface, could reduce astrogliosis around the site of implantation. © 2013 American Chemical Society.
  • Published In

  • Nano Letters  Journal
  • Digital Object Identifier (doi)

    Author List

  • Gottipati MK; Samuelson JJ; Kalinina I; Bekyarova E; Haddon RC; Parpura V
  • Start Page

  • 4387
  • End Page

  • 4392
  • Volume

  • 13
  • Issue

  • 9