Hypothalamic catecholamine changes under acute stress occur independently of nicotinic stimulation

Academic Article


  • Nicotine and acute stress both decrease hypothalamic epinephrine and norepinephrine concentrations and increase the concentration of the dopamine metabolite dihydroxyphenylacetic acid. The nicotinic antagonist mecamylamine blocks the effects of nicotine on hypothalamic catecholamines, yet fails to alter the stress induced changes in hypothalamic catecholamines. These results suggest that the stress-induced changes in hypothalamic catecholamines occur independently of nicotinic receptor activation. © 1982.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Roth KA; McIntire SL; Lorenz RG; Barchas JD
  • Start Page

  • 47
  • End Page

  • 50
  • Volume

  • 28
  • Issue

  • 1