Protracted pneumonitis in young infants associated with perinatally acquired cytomegaloviral infection

Academic Article


  • Two infants developed a protracted pneumonitis with lower respiratory obstruction beginning at one month of age. Lung biopsy in one suggested a viral etiology whith prompted an extensive investigation of each infant for specific etiology. Virologic, serologic, immunologic, and electronmicroscopic studies indicated that cytomegalovirus was a major causative factor. The infections were apparently acquired at birth from infected maternal genital tracts and have persisted for prolonged periods of time. Evidence for gross immunologic defect as a precipitating cause was lacking. These infants serve to emphasize the possible pathologic potential of CMV when acquired in early life even in the absence of iatrogenic immunosuppression. © 1976 The C. V. Mosby Company.
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    Digital Object Identifier (doi)

    Author List

  • Whitley RJ; Brasfield D; Reynolds DW; Stagno S; Tiller RE; Alford CA
  • Start Page

  • 16
  • End Page

  • 22
  • Volume

  • 89
  • Issue

  • 1