Mind the gap: How some viruses infect their hosts

Academic Article


  • Cryo-electron microscopy (Cryo-EM) and cryo-electron tomography (Cryo-ET) provide structural insights into complex biological processes. The podoviridae are dsDNA containing phage with short, non-contractile tails which nevertheless translocate their DNA into the cytoplasm of their host cells. Liu et al. [1] used a combination of cryo-EM and cryo-ET to study the structural changes accompanying infection of P. marinus by the phage P-SSP7 and thereby provide unique molecular insight into the process by which the DNA transits from phage to host during infection.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 21196788
  • Author List

  • Prevelige PE
  • Start Page

  • 2536
  • End Page

  • 2540
  • Volume

  • 2
  • Issue

  • 11