Airway obstruction is increased in Pneumocystis-colonized human immunodeficiency virus-infected outpatients

Academic Article

Abstract

  • We investigated the relationship of Pneumocystis colonization, matrix metalloprotease levels in sputum, and airway obstruction in a cohort of human immunodeficiency virus (HIV)-infected outpatients. Pneumocystis-colonized subjects had worse obstruction of airways and higher levels of matrix metalloprotease-12 in sputa, suggesting that Pneumocystis colonization may be important in HIV-associated chronic obstructive pulmonary disease. Copyright © 2009, American Society for Microbiology. All Rights Reserved.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Morris A; Alexander T; Radhi S; Lucht L; Sciurba FC; Kolls JK; Srivastava R; Steele C; Norris KA
  • Start Page

  • 3773
  • End Page

  • 3776
  • Volume

  • 47
  • Issue

  • 11