To the Editor: Galve et al. (Sept. 29 issue)1 reported on their experience with cardiac valvular involvement in 74 patients with systemic lupus erythematosus. They studied their patients with echocardiography and reported an 18 percent prevalence of valvular involvement, including lesions suggestive of Libman-Sacks endocarditis, and valvular thickening with both stenosis and regurgitation, especially of the mitral valve. We have also prospectively looked for cardiac valvular lesions in Chinese patients with systemic lupus erythematosus. We studied 50 female patients with lupus and 43 matched normal controls with echocardiography and continuous-wave Doppler analysis with simultaneous imaging. All the patients studied met. © 1989, Massachusetts Medical Society. All rights reserved.