The modern Fontan operation shows no increase in mortality out to 20 years: A new paradigm

Academic Article

Abstract

  • Results At 1, 10, and 20 years, survival for the entire cohort was 95%, 88%, and 76%, respectively, with no deaths in the last 6 years of the study. Hazard modeling showed a 1.3% risk of death per year 24 years after the Fontan procedure, with no late increasing hazard phase. Freedom from reoperations was greater than 90% at 20 years and freedom from thrombotic complications was 98% at 20 years (with greater than 80% of patients on aspirin alone). Survival curves were superimposable for 16- to 20-mm conduits, and the freedom from any reoperation including transplantation was greater than 90% after 20 years. Multivariable risk factor analysis identified only earlier date of operation as a predictor of early and late mortality. By era of surgery, the 10-year predicated survival is 89% for patients undergoing surgery in 2000 and 94% for patients in 2010.
  • Digital Object Identifier (doi)

    Author List

  • Dabal RJ; Kirklin JK; Kukreja M; Brown RN; Cleveland DC; Eddins MC; Lau Y
  • Start Page

  • 2517
  • End Page

  • 2524.e1
  • Volume

  • 148
  • Issue

  • 6