Apolipoprotein E genotype does not affect the age of onset of dementia in families with defined tau mutations

Academic Article


  • We have assessed whether apolipoprotein E (ApoE) genotype influences the age of onset of dementia in a series of families with frontal temporal dementia with defined mutations in the tau gene. In contrast to the situation in Alzheimer's disease (AD), we could find no evidence that the age of onset of disease was influenced by the ApoE genotype.
  • Authors

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    Digital Object Identifier (doi)

    Author List

  • Houlden H; Rizzu P; Stevens M; De Knijff P; Van Duijn CM; Van Swieten JC; Heutink P; Perez-Tur J; Thomas V; Baker M
  • Start Page

  • 193
  • End Page

  • 195
  • Volume

  • 260
  • Issue

  • 3