Screening for cardiac dysfunction in anthracycline-exposed childhood cancer survivors

Academic Article

Abstract

  • Experimental Design: Using a cross-sectional design, anthracycline-exposed childhood cancer survivors with preserved ejection fraction (EF; -≥50%) were evaluated using early echocardiographic indices and blood biomarkers of LV dysfunction. Survivors treated with -≥300 mg/m2 anthracyclines [high risk (HR): n = 100] were compared with those treated with <300 mg/m2 anthracyclines [low risk (LR): n = 50] and matched healthy controls (HC: n = 50). All echocardiograms were interpreted by an institutional cardiologist and a study cardiologist blinded to risk status.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Armenian SH; Gelehrter SK; Vase T; Venkatramani R; Lier W; Wilson KD; Herrera C; Reichman L; Menteer JD; Mascarenhas L
  • Start Page

  • 6314
  • End Page

  • 6323
  • Volume

  • 20
  • Issue

  • 24